Irena Žižović - Academia.edu (original) (raw)

Papers by Irena Žižović

Experiments in this study were aimed to investigate a potential of the most abundant red grape va... more Experiments in this study were aimed to investigate a potential of the most abundant red grape varieties from the central part of Serbia (the region of three Morava rivers) for grape oil manufacturing, using a Supercritical CO2 extraction. Special significance of the experiments was characterization of the main constituents of the grape seed oils from the indigenous variety Prokupac and comparison with selected the most commonly grown international varieties ( Cabernet Sauvignon, Pinot Noir, Merlot and Gamay). Faty acids prophyl, content of the biologically active copmounds (total phenolic compounds and α-tocopherol) were determined. Based on DSC method, by oxidation onset temperature determination, oxidative stability of the oils were estimated. Fatty acids composition was in accordance with data in the literature. In terms of the α-tocopherol content, low quantity was determined in oils from all grape seed varieties. At used extraction parameters limited extraction of the α-tocoph...

Nova Science Publishers, Inc. eBooks, 2017

The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provi... more The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provides flexibility, controlled adherence to the surrounding tissue, gas permeability, durability and absorbance of fluids exuded from the wound but doesn't provide therapeutic treatment. Therapeutic effect can be provided by incorporation of an active ingredient into gauze. In this chapter, supercritical solvent impregnation of cotton gauze with carvacrol is proposed with an aim to impart antibacterial properties to cotton fibres. State of the art in fabrication of textiles with natural bioactive substances, antibacterial activity of carvacrol loaded materials as well as in the use of supercritical fluids in textile material impregnation is presented. The importance of the application of natural substances with strong antibacterial properties in modern age when the world is facing problem of bacterial resistance to antibiotics is stressed and the future application of cotton as a wound dressing is discussed

Polymer Engineering & Science, 2018

Supercritical carbon dioxide (scCO 2) technology was used for preparation of functional pH sensit... more Supercritical carbon dioxide (scCO 2) technology was used for preparation of functional pH sensitive chitosan-based aerogels characterized with micron size pores and their impregnation with thymol as a natural bioactive substance. Hydrogels based on chitosan, itaconic and methacrylic acids were transformed to alcogels and dried in the air or with scCO 2 to obtain xero-and aerogels, respectively. Applying 10 min of static and 120 min of dynamic scCO 2 drying at 11 MPa and 458C followed with the decompression at a rate of 1 MPa/min yielded an advantageous aerogel with favorable swelling kinetics and elasticity, compared to the xerogel and aerogels obtained at other decompression rates and drying times. This aerogel was successfully loaded with thymol (up to 4.6 wt.%) using supercritical scCO 2 at 10 MPa and 358C. In vitro studies of swelling in PBS at 378C indicated a great potential of the obtained stimuli-responsive chitosan gels for topical administration of thymol known for antimicrobial, antioxidant and anti-inflammatory activities. POLYM. ENG.

Open Chemistry, 2015

Extracts obtained from hops (Humulus lupulus L., Cannabaceae) by supercritical fluid extraction (... more Extracts obtained from hops (Humulus lupulus L., Cannabaceae) by supercritical fluid extraction (SFE), SFE followed by isomerization, as well as by conventional technique, were investigated for their chemical composition and antibacterial activity against selected foodborne pathogens and microorganisms capable to cause the food spoilage. The antibacterial activity of the extracts was compared with the antibacterial activity of xanthohumol, compound known for its broad pharmacological properties, isolated from the raw material remained after the SFE. Xanthohumol (XH, 96%) proved to posses the most prominent activity against all the tested strains, with the MIC values ranged between 2.5 and 20 μg mL-1. Supercritical hops extract and potassium isomerized supercritical hops extract showed strong antibacterial activity against the tested strains as well. Escherichia coli was not affected by the extracts, meaning that their oral admission would not cause the same problem as antibiotic app...

International Journal of Polymer Science, 2017

Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose aceta... more Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50°C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6–60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0–33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled...

Experiments in this study were aimed to investigate a potential of the most abundant red grape va... more Experiments in this study were aimed to investigate a potential of the most abundant red grape varieties from the central part of Serbia (the region of three Morava rivers) for grape oil manufacturing, using a Supercritical CO2 extraction. Special significance of the experiments was characterization of the main constituents of the grape seed oils from the indigenous variety Prokupac and comparison with selected the most commonly grown international varieties ( Cabernet Sauvignon, Pinot Noir, Merlot and Gamay). Faty acids prophyl, content of the biologically active copmounds (total phenolic compounds and α-tocopherol) were determined. Based on DSC method, by oxidation onset temperature determination, oxidative stability of the oils were estimated. Fatty acids composition was in accordance with data in the literature. In terms of the α-tocopherol content, low quantity was determined in oils from all grape seed varieties. At used extraction parameters limited extraction of the α-tocoph...

Nova Science Publishers, Inc. eBooks, 2017

The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provi... more The use of cotton in wound dressing applications is discussed in this chapter. Cotton gauze provides flexibility, controlled adherence to the surrounding tissue, gas permeability, durability and absorbance of fluids exuded from the wound but doesn't provide therapeutic treatment. Therapeutic effect can be provided by incorporation of an active ingredient into gauze. In this chapter, supercritical solvent impregnation of cotton gauze with carvacrol is proposed with an aim to impart antibacterial properties to cotton fibres. State of the art in fabrication of textiles with natural bioactive substances, antibacterial activity of carvacrol loaded materials as well as in the use of supercritical fluids in textile material impregnation is presented. The importance of the application of natural substances with strong antibacterial properties in modern age when the world is facing problem of bacterial resistance to antibiotics is stressed and the future application of cotton as a wound dressing is discussed

Polymer Engineering & Science, 2018

Supercritical carbon dioxide (scCO 2) technology was used for preparation of functional pH sensit... more Supercritical carbon dioxide (scCO 2) technology was used for preparation of functional pH sensitive chitosan-based aerogels characterized with micron size pores and their impregnation with thymol as a natural bioactive substance. Hydrogels based on chitosan, itaconic and methacrylic acids were transformed to alcogels and dried in the air or with scCO 2 to obtain xero-and aerogels, respectively. Applying 10 min of static and 120 min of dynamic scCO 2 drying at 11 MPa and 458C followed with the decompression at a rate of 1 MPa/min yielded an advantageous aerogel with favorable swelling kinetics and elasticity, compared to the xerogel and aerogels obtained at other decompression rates and drying times. This aerogel was successfully loaded with thymol (up to 4.6 wt.%) using supercritical scCO 2 at 10 MPa and 358C. In vitro studies of swelling in PBS at 378C indicated a great potential of the obtained stimuli-responsive chitosan gels for topical administration of thymol known for antimicrobial, antioxidant and anti-inflammatory activities. POLYM. ENG.

Open Chemistry, 2015

Extracts obtained from hops (Humulus lupulus L., Cannabaceae) by supercritical fluid extraction (... more Extracts obtained from hops (Humulus lupulus L., Cannabaceae) by supercritical fluid extraction (SFE), SFE followed by isomerization, as well as by conventional technique, were investigated for their chemical composition and antibacterial activity against selected foodborne pathogens and microorganisms capable to cause the food spoilage. The antibacterial activity of the extracts was compared with the antibacterial activity of xanthohumol, compound known for its broad pharmacological properties, isolated from the raw material remained after the SFE. Xanthohumol (XH, 96%) proved to posses the most prominent activity against all the tested strains, with the MIC values ranged between 2.5 and 20 μg mL-1. Supercritical hops extract and potassium isomerized supercritical hops extract showed strong antibacterial activity against the tested strains as well. Escherichia coli was not affected by the extracts, meaning that their oral admission would not cause the same problem as antibiotic app...

International Journal of Polymer Science, 2017

Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose aceta... more Supercritical CO2 was used as a green solvent and impregnation medium for loading cellulose acetate beads with carvacrol in order to obtain a biomaterial with antibacterial properties. Supercritical solvent impregnation was performed in a high-pressure view cell at temperature of 50°C and pressures of 10, 21, and 30 MPa with the processing time ranging from 2 to 18 h. The rate of impregnation increased with the pressure increase. However, maximum impregnation yield (round 60%) was not affected by the pressure applied. Selected samples of the impregnated cellulose acetate containing 6–60% of carvacrol were proven to have considerable antibacterial effect against Gram-positive and Gram-negative bacterial strains including methicillin-resistant Staphylococcus aureus which causes severe infections in humans and animals. In addition, cellulose acetate beads containing 6.0–33.6% of carvacrol were shown to have a porous structure with submicron pores which is of interest for the controlled...