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Papers by Irena Komendova

Souvislost mezi neurovývojovými poruchami a poruchami funkce stitne žlazy po narozeni je znama vi... more Souvislost mezi neurovývojovými poruchami a poruchami funkce stitne žlazy po narozeni je znama vice jak stoleti. Avsak důležitost hormonů stitne žlazy pro plod během těhotenstvi byla potvrzena až na konci 20. stoleti. Trvalo vsak jestě dalsich deset let, než doslo k obecne shodě o důležitosti tyreoidalnich hormonů matky pro vývoj plodu ve druhem a třetim trimestru. Stale je vsak nejiste zda ma tyreopatie matky vliv na vývoj plodu už v prvnim trimestru těhotenstvi, kdy je plod zcela zavislý na hormonech stitne žlazy matky. V letech 2004-2006 byly shromažděny výsledky vysetřeni funkce stitne žlazy u 1649 těhotných žen v oblasti Havlickobrodska. Osm let po zacatku screeningu jsme provedli vysetřeni intelektu 267 děti, ktere se těmto ženam narodily. Nasledným výběrem byla vytvořena výzkumna skupina 74 děti matek s nelecenou tyreopatii v prvnim trimestru těhotenstvi (TSH větsi ci rovno 3,5 a/nebo TPO-Ab větsi ci rovno 20), jejiž výkon v inteligencnim testu byl srovnan s kontrolni skupinou 132 děti, jejichž matky v době těhotenstvi nevykazovaly poruchu funkce stitne žlazy. Nebyl nalezen statisticky významný rozdil ve výkonu děti ve výzkumne a kontrolni skupině. V obou skupinach děti celkově podaly průměrný výkon, což odpovida normalnimu populacnimu rozloženi.

ACM Symposium on Eye Tracking Research and Applications, Jun 2, 2020

Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether peopl... more Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether people with this disease do avoid eye-contact and the view on human faces remains uncertain. An extensive body of eye-tracking research tries to answer this question, but results are inconsistent probably due to different approaches and other methodological specifics. This is the reason for my focus on the topic, where I try to determine factors contributing to this uncertainity and to come closer to the answer. Currently, I am working on a meta-analysis and preparing quasi-experiment, where I compare children with asd and children of the same age with neurotypical development, using eye-tracking technology and pictures with social context, specifically human faces.

Introduction: The focus of the present study was the importance of the mother's thyroid function ... more Introduction: The focus of the present study was the importance of the mother's thyroid function for foetal development in the first trimester, when the baby is totally dependent on the mother for thyroid hormones. Materials and methods: The study consisted of testing the intellectual performance of children with both euthyroid and thyroid-dysfunction mothers. The experimental group comprised 60 children of mothers with an untreated thyroid disorder in the first trimester of pregnancy (TSH ≥ 3.5 mlU/L [standard 0.15-3.5] and/or TPO-Ab ≥ 20 lU/L [standard < 20]). The control group contained 132 children whose mothers showed no symptoms of a thyroid disorder either before or during pregnancy/postpartum. Both groups of children were administered the Wechsler Intelligence Scale for Children-Third Edition (WISC-III), whereby the intellectual performance of the experimental-group children was compared with that of the control-group children. The comparison included the percentage of children with IQ ≤ 85 and SLD and/or ADD risks. Our research is a follow-up to a blanket thyroid screening of 1649 pregnant women conducted during 2004-2006 in the region around Havlíčkův Brod. Results: The research found no significant difference between the two groups of children with respect to their intellectual abilities, either regarding their overall IQ (p = 0.67), verbal IQ (p = 0.81), performance IQ (p = 0.41), or the individual scores (VCI: p = 0.85; POI: p = 0.54, FDI: p = 0.57; PSI: p = 0.13), nor did the experimental group show a significantly higher occurrence of children with IQ ≤ 85 than the control group (p = 0.66). However, the experimental group did exhibit a statistically significant increase in the percentage of children with a suspected SLD or clinically significant attention issues (p = 0.05). Conclusion: Untreated thyroid disorders in the first trimester of pregnancy can increase the risk of the child developing attention or learning issues.

Teměř 10 % populace trpi nějakou formou poruchy osobnosti (PO). S PO se poji jak psychicke tak so... more Teměř 10 % populace trpi nějakou formou poruchy osobnosti (PO). S PO se poji jak psychicke tak somaticke potiže, přicemž pece o tyto pacientky je narocna nejen financně, ale i psychicky pro vsechny zucastněne. Porucha osobnosti neni nemoc v pravem slova smyslu a jeji lecba je svizelna, přicemž psychofarmakologicka lecba může zlepsit doprovodnou symptomatologii, avsak nedokaže vyřesit osobnostni deficity. Psychoterapie pak může pacientovi pomoci dozrat v některých aspektech jeho osobnosti, ale uplne vyleceni poruchy osobnosti je nemožne. Přesto se tito pacienti setkavaji s nepochopenim. Lepsimu porozuměni teto diagnozy na straně zdravotniky somatických oborů mediciny může napomoci lepsimu pochopeni pacientů s PO, vyhnout se jeho stigmatizaci a docilit lepsi spoluprace.

Phantom pain results in up to 85 % of amputees. It is very difficult to treat and remains puzzlin... more Phantom pain results in up to 85 % of amputees. It is very difficult to treat and remains puzzling phenomenon. This article focuses on practical application of hypnosis in treating phantom limb pain as a promising approach to phantom pain management. Review of studies using hypnotherapy is introduced as an opportunity for practicing hypnotherapist to familiarize themselves with possible proceedings. The outcome reports for hypnotherapy have been mainly positive and show a reduction in phantom limb pain as can be also seen in four author´s case studies included. However, firm conclusion cannot be made as we lack well controlled and randomized trials of effectiveness of hypnotherapy in the treatment of phantom limb pain.

Fantomova bolest se vyskytuje nejen po chirurgickem ci traumatickem odstraněni koncetiny, ale i j... more Fantomova bolest se vyskytuje nejen po chirurgickem ci traumatickem odstraněni koncetiny, ale i jiných casti těla, při poraněni pateře, odtrženi brachialniho plexu a taktež u děti s kongenitalni aplazii koncetiny. Rozviji se až u 85 % pacientů a zůstava stale matoucim fenomenem. Důležitou soucasti pece o pacienta s fantomovou bolesti je i psychologicka lecba, přicemž jako velmi ucinna se jevi hypnoterapie. Tento clanek se zaměřuje na možnosti hypnoterapie u pacientů s fantomovou bolesti koncetiny, vcetně přehledu dosud publikovaných studii na dane tema.

Annales de Dermatologie et de Vénéréologie, 2010

Through its visible clinical aspect, acne induces a significantly impaired body image which is no... more Through its visible clinical aspect, acne induces a significantly impaired body image which is not correlated to clinical severity. This diminished body image and the resulting psychosocial behaviour must be considered to optimize the treatment. In addition, depressive disorders related to bodily concern are frequently observed during adolescence period and faced with these bodily transformations, acne can be a source of anxiety. It is therefore important to spot the symptoms of depression and indeed treat them if they are persistent, because they impair &quot;self-image&quot; and have an influence on the wish to &quot;take care of oneself&quot;.

The link between impaired neurodevelopment and thyroid dysfunction after birth has been well-know... more The link between impaired neurodevelopment and thyroid dysfunction after birth has been well-known for more than 100 years. The general agreement about the importance of thyroid hormones for the development of CNS of a fetus in the second and third trimester of pregnancy has been reached only 15 years ago. Whether maternal thyroid dysfunction has negative impact on the fetus development in the first trimester of pregnancy, when the fetus is utterly dependent on maternal thyroid hormones, is unknown. Between 2004 and 2006, thyroid function tests were gathered in 1649 pregnant women of the Havlíčkův Brod area. Eight years after this screening begun, we assessed intellectual performance in 267 children of women from the screening. Consequent selection provided a screening group A of 74 children of women with untreated thyroid dysfunction in the first trimester of pregnancy (TSH≥3,5 and/or TPO-Ab≥20). Intellectual performance of these children in WISC-III was compared with control group...

ACM Symposium on Eye Tracking Research and Applications, 2020

Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether peopl... more Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether people with this disease do avoid eye-contact and the view on human faces remains uncertain. An extensive body of eye-tracking research tries to answer this question, but results are inconsistent probably due to different approaches and other methodological specifics. This is the reason for my focus on the topic, where I try to determine factors contributing to this uncertainity and to come closer to the answer. Currently, I am working on a meta-analysis and preparing quasi-experiment, where I compare children with asd and children of the same age with neurotypical development, using eye-tracking technology and pictures with social context, specifically human faces.

Souvislost mezi neurovývojovými poruchami a poruchami funkce stitne žlazy po narozeni je znama vi... more Souvislost mezi neurovývojovými poruchami a poruchami funkce stitne žlazy po narozeni je znama vice jak stoleti. Avsak důležitost hormonů stitne žlazy pro plod během těhotenstvi byla potvrzena až na konci 20. stoleti. Trvalo vsak jestě dalsich deset let, než doslo k obecne shodě o důležitosti tyreoidalnich hormonů matky pro vývoj plodu ve druhem a třetim trimestru. Stale je vsak nejiste zda ma tyreopatie matky vliv na vývoj plodu už v prvnim trimestru těhotenstvi, kdy je plod zcela zavislý na hormonech stitne žlazy matky. V letech 2004-2006 byly shromažděny výsledky vysetřeni funkce stitne žlazy u 1649 těhotných žen v oblasti Havlickobrodska. Osm let po zacatku screeningu jsme provedli vysetřeni intelektu 267 děti, ktere se těmto ženam narodily. Nasledným výběrem byla vytvořena výzkumna skupina 74 děti matek s nelecenou tyreopatii v prvnim trimestru těhotenstvi (TSH větsi ci rovno 3,5 a/nebo TPO-Ab větsi ci rovno 20), jejiž výkon v inteligencnim testu byl srovnan s kontrolni skupinou 132 děti, jejichž matky v době těhotenstvi nevykazovaly poruchu funkce stitne žlazy. Nebyl nalezen statisticky významný rozdil ve výkonu děti ve výzkumne a kontrolni skupině. V obou skupinach děti celkově podaly průměrný výkon, což odpovida normalnimu populacnimu rozloženi.

ACM Symposium on Eye Tracking Research and Applications, Jun 2, 2020

Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether peopl... more Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether people with this disease do avoid eye-contact and the view on human faces remains uncertain. An extensive body of eye-tracking research tries to answer this question, but results are inconsistent probably due to different approaches and other methodological specifics. This is the reason for my focus on the topic, where I try to determine factors contributing to this uncertainity and to come closer to the answer. Currently, I am working on a meta-analysis and preparing quasi-experiment, where I compare children with asd and children of the same age with neurotypical development, using eye-tracking technology and pictures with social context, specifically human faces.

Introduction: The focus of the present study was the importance of the mother's thyroid function ... more Introduction: The focus of the present study was the importance of the mother's thyroid function for foetal development in the first trimester, when the baby is totally dependent on the mother for thyroid hormones. Materials and methods: The study consisted of testing the intellectual performance of children with both euthyroid and thyroid-dysfunction mothers. The experimental group comprised 60 children of mothers with an untreated thyroid disorder in the first trimester of pregnancy (TSH ≥ 3.5 mlU/L [standard 0.15-3.5] and/or TPO-Ab ≥ 20 lU/L [standard < 20]). The control group contained 132 children whose mothers showed no symptoms of a thyroid disorder either before or during pregnancy/postpartum. Both groups of children were administered the Wechsler Intelligence Scale for Children-Third Edition (WISC-III), whereby the intellectual performance of the experimental-group children was compared with that of the control-group children. The comparison included the percentage of children with IQ ≤ 85 and SLD and/or ADD risks. Our research is a follow-up to a blanket thyroid screening of 1649 pregnant women conducted during 2004-2006 in the region around Havlíčkův Brod. Results: The research found no significant difference between the two groups of children with respect to their intellectual abilities, either regarding their overall IQ (p = 0.67), verbal IQ (p = 0.81), performance IQ (p = 0.41), or the individual scores (VCI: p = 0.85; POI: p = 0.54, FDI: p = 0.57; PSI: p = 0.13), nor did the experimental group show a significantly higher occurrence of children with IQ ≤ 85 than the control group (p = 0.66). However, the experimental group did exhibit a statistically significant increase in the percentage of children with a suspected SLD or clinically significant attention issues (p = 0.05). Conclusion: Untreated thyroid disorders in the first trimester of pregnancy can increase the risk of the child developing attention or learning issues.

Teměř 10 % populace trpi nějakou formou poruchy osobnosti (PO). S PO se poji jak psychicke tak so... more Teměř 10 % populace trpi nějakou formou poruchy osobnosti (PO). S PO se poji jak psychicke tak somaticke potiže, přicemž pece o tyto pacientky je narocna nejen financně, ale i psychicky pro vsechny zucastněne. Porucha osobnosti neni nemoc v pravem slova smyslu a jeji lecba je svizelna, přicemž psychofarmakologicka lecba může zlepsit doprovodnou symptomatologii, avsak nedokaže vyřesit osobnostni deficity. Psychoterapie pak může pacientovi pomoci dozrat v některých aspektech jeho osobnosti, ale uplne vyleceni poruchy osobnosti je nemožne. Přesto se tito pacienti setkavaji s nepochopenim. Lepsimu porozuměni teto diagnozy na straně zdravotniky somatických oborů mediciny může napomoci lepsimu pochopeni pacientů s PO, vyhnout se jeho stigmatizaci a docilit lepsi spoluprace.

Phantom pain results in up to 85 % of amputees. It is very difficult to treat and remains puzzlin... more Phantom pain results in up to 85 % of amputees. It is very difficult to treat and remains puzzling phenomenon. This article focuses on practical application of hypnosis in treating phantom limb pain as a promising approach to phantom pain management. Review of studies using hypnotherapy is introduced as an opportunity for practicing hypnotherapist to familiarize themselves with possible proceedings. The outcome reports for hypnotherapy have been mainly positive and show a reduction in phantom limb pain as can be also seen in four author´s case studies included. However, firm conclusion cannot be made as we lack well controlled and randomized trials of effectiveness of hypnotherapy in the treatment of phantom limb pain.

Fantomova bolest se vyskytuje nejen po chirurgickem ci traumatickem odstraněni koncetiny, ale i j... more Fantomova bolest se vyskytuje nejen po chirurgickem ci traumatickem odstraněni koncetiny, ale i jiných casti těla, při poraněni pateře, odtrženi brachialniho plexu a taktež u děti s kongenitalni aplazii koncetiny. Rozviji se až u 85 % pacientů a zůstava stale matoucim fenomenem. Důležitou soucasti pece o pacienta s fantomovou bolesti je i psychologicka lecba, přicemž jako velmi ucinna se jevi hypnoterapie. Tento clanek se zaměřuje na možnosti hypnoterapie u pacientů s fantomovou bolesti koncetiny, vcetně přehledu dosud publikovaných studii na dane tema.

Annales de Dermatologie et de Vénéréologie, 2010

Through its visible clinical aspect, acne induces a significantly impaired body image which is no... more Through its visible clinical aspect, acne induces a significantly impaired body image which is not correlated to clinical severity. This diminished body image and the resulting psychosocial behaviour must be considered to optimize the treatment. In addition, depressive disorders related to bodily concern are frequently observed during adolescence period and faced with these bodily transformations, acne can be a source of anxiety. It is therefore important to spot the symptoms of depression and indeed treat them if they are persistent, because they impair &quot;self-image&quot; and have an influence on the wish to &quot;take care of oneself&quot;.

The link between impaired neurodevelopment and thyroid dysfunction after birth has been well-know... more The link between impaired neurodevelopment and thyroid dysfunction after birth has been well-known for more than 100 years. The general agreement about the importance of thyroid hormones for the development of CNS of a fetus in the second and third trimester of pregnancy has been reached only 15 years ago. Whether maternal thyroid dysfunction has negative impact on the fetus development in the first trimester of pregnancy, when the fetus is utterly dependent on maternal thyroid hormones, is unknown. Between 2004 and 2006, thyroid function tests were gathered in 1649 pregnant women of the Havlíčkův Brod area. Eight years after this screening begun, we assessed intellectual performance in 267 children of women from the screening. Consequent selection provided a screening group A of 74 children of women with untreated thyroid dysfunction in the first trimester of pregnancy (TSH≥3,5 and/or TPO-Ab≥20). Intellectual performance of these children in WISC-III was compared with control group...

ACM Symposium on Eye Tracking Research and Applications, 2020

Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether peopl... more Despite being a part of the official diagnostics of autism spectrum disorder (asd), whether people with this disease do avoid eye-contact and the view on human faces remains uncertain. An extensive body of eye-tracking research tries to answer this question, but results are inconsistent probably due to different approaches and other methodological specifics. This is the reason for my focus on the topic, where I try to determine factors contributing to this uncertainity and to come closer to the answer. Currently, I am working on a meta-analysis and preparing quasi-experiment, where I compare children with asd and children of the same age with neurotypical development, using eye-tracking technology and pictures with social context, specifically human faces.