Irfan Celebi - Academia.edu (original) (raw)

Papers by Irfan Celebi

CRC Press eBooks, Oct 21, 2013

Poster: "ESSR 2016 / P-0066 / Magnetic resonance imaging assesment of Lateral Meniscus anter... more Poster: "ESSR 2016 / P-0066 / Magnetic resonance imaging assesment of Lateral Meniscus anterior horn tear with parameniscal cyst in Hoffa ‘s fat Pad;Unusual combination of pathology in young population" by: "M. Bankaoglu, A. S. Mahmutoglu, U. Erdem, I. Celebi, S. M. Erturk; Istanbul/TR"

Auris Nasus Larynx, Jun 1, 2018

Treatments for cancers of the larynx include various options, such as chemo-and/or radiotherapy, ... more Treatments for cancers of the larynx include various options, such as chemo-and/or radiotherapy, transoral laser microsurgery (TLM), open partial laryngectomy, and total laryngectomy [1]. The purpose of these treatments is to provide disease control with minimal morbidity. Appropriate treatment is determined by clinical findings, including the general health status of the patient, tumor spread as detected by endoscopic/ laryngoscopic examinations, and pathological and radiological characteristics of the tumor. The preepiglottic space (PES), with its fatty and lymphaticrich structure, is one of the pathways for submucosal tumor spread in laryngeal cancers (Fig. 1) [2]. PES involvement is encountered frequently in advanced-stage carcinomas of the supraglottis and Auris Nasus Larynx xxx (2017) xxx-xxx

American Journal of Rhinology & Allergy, Nov 1, 2015

Objective To evaluate the amount and type of osteitis observed in chronic rhinosinusitis with nas... more Objective To evaluate the amount and type of osteitis observed in chronic rhinosinusitis with nasal polyposis (CRSwNP) and compare it with that of chronic rhinosinusitis without nasal polyposis (CRSnNP). Setting Sisli Etfal Research and Education Hospital, Istanbul, Turkey. Study Design Prospective, single-blind, cohort study. Methods Three different patient groups, designated as the CRSwNP, CRSnNP, and control groups, were included in the study. Forty patients who had CRSnNP and/or CRSwNP confirmed with a paranasal sinus computerized tomography (CT) study were included for the study group, and 20 individuals were included in the control group. Paranasal sinus CTs were evaluated and compared for osteitis. Results Hounsfield units obtained from the right and left agger nasi walls and the medial maxillary sinus wall in the control group were significantly different from the entire group. Similarly, values for the anterior ethmoid wall were statistically significant for the CRSwNP group compared with all the subjects. When the groups were compared to one another, there were significant differences in both the right and left agger nasi walls and the frontal sinus wall. Conclusion Differentiating and acknowledging osteitis induced by CRSwNP rather than CRSnNP may aid in preoperative planning and indicate where to be more aggressive when excising bony structures. This may help in reducing recurrence and in increasing quality of life.

Istanbul Medical Journal, Dec 14, 2017

Tinnitus is described as an auditory sensation felt in the absence of an external stimulus (1). I... more Tinnitus is described as an auditory sensation felt in the absence of an external stimulus (1). It affects approximately 12% of the population in Western countries (2, 3). Although audiometric evaluation can be useful to reveal the source of tinnitus (Meniere's disease, otosclerosis, or noise-induced hearing loss), the existence of disabling symptoms causes radiological evaluation to be unavoidable (4, 5). Tinnitus is characterized as objective or subjective and pulsatile or nonpulsatile. Pulsatile tinnitus (PT) harmonizes with the heartbeat of the patient, whereas nonpulsatile tinnitus does not. Tinnitus can be subjective (perceived only by the patient) or objective (can be perceived by others). Subjective tinnitus is more common than objective tinnitus. PT may be either subjective or objective. As for nonpulsatile tinnitus, it is subjective in most of the cases. Subjective nonpulsatile tinnitus is the most frequently observed type of tinnitus, and most probably the cause is least likely to be treatable (6, 7). Radiologic studies should follow a full clinical evaluation including neuro-otologic examination with otoscopy and audiologic assessment. The most appropriate imaging technique can be determined after characterization of the tinnitus and detailed clinical evaluation (8-10). The cause of PT is most probably going to be a vascular abnormality or vascular tumor. By virtue of the fact that these vascular lesions often involve the middle ear and otic capsule where MR is less sensitive, computed tomography (CT) becomes more valuable and intravenous contrast administration also facilitates the imaging of vascular structures (11-13). Methods The temporal bone CT images of 35 patients with subjective PT (SPT), who were admitted to our hospital between October 2013 and May 2014, were evaluated. The study group consisted of pa-Can The Configuration of Petrous Bone Pneumatization be a Predictor of Tinnitus? Introduction: In this study, we tried to evaluate a possible relationship between petrous bone pneumatization and subjective pulsatile tinnitus (SPT). Methods: The temporal bone computed tomographic (CT) images of 35 patients with SPT admitted to our hospital between October 2013 and May 2014 were evaluated. We formed the control group by a retrospective evaluation of the reconstructed images of the petrous bones derived from the paranasal CT scans of 35 patients free of SPT complaints performed because of chronic sinusitis. Results: Overall, 46 ears of patients with SPT were evaluated. Of these, 13 (28.26%) had petrous bone pneumatization. Of these, 11 of them had increased pneumatization formed of small aircells, whereas two had predominant large aircells between internal carotid artery (ICA) and cochlea. In the control group, 15 (21.42%) of 70 ears had petrous bone pneumatization formed of small air cells. On comparing study and control groups, no significant relationship was found between petrous pneumatization and tinnitus (p>0.05). Conclusion: In our study, we did not find any significant relationship between pneumatization and tinnitus, but we detected two patients with bilateral pneumatization, who had SPT at the side of pneumatization, which mainly consisted of a unibody large air cell; however, the opposite sides, which consisted of multiple small aircells, were free of tinnitus. For these cases, a question arises whether a combination of thin bony lamellas and tiny air cells together causing multiple interfaces resulting in dispersion and reflection, thus reducing the energy of the sound and existence of a unibody large aircell conducting the sound with relatively less distortion, eventually resulting in not amplification but less interference on the sound can be perceived by cochlea as relatively increased conduction of the blood flow and result in SPT. To prove this theory, a study with a large number of cases in resemblance has to be conducted..

Journal of International Advanced Otology, Jan 21, 2019

PubMed, Dec 1, 2006

Glomus tumors, especially with some definitive MR imaging features, are diagnosed easily. However... more Glomus tumors, especially with some definitive MR imaging features, are diagnosed easily. However, when two glomus tumors are suspected in one single mass, careful evaluation is necessary. We report one patient with two synchronous glomus tumors, ipsilateral glomus tumor of the carotid body and glomus vagale on the right neck, simulating a single mass.

Journal of the European Academy of Dermatology and Venereology, 2020

International Journal of Infectious Diseases, 2020

This study aimed to describe the effectiveness and optimum use of tocilizumab (TCZ) treatment by ... more This study aimed to describe the effectiveness and optimum use of tocilizumab (TCZ) treatment by the support of clinical, laboratory and radiologic observations. Methods: All patients were followed up in the hospital with daily interleukin-6 (IL-6), C-reactive protein (CRP), ferritin, D-dimer, full blood count, and procalcitonin. Thoracic computed tomography (CT) was performed on admission, when oxygen support was necessary, and seven days after TCZ started. Disease course of the patients was grouped as severe or critical, according to their clinical, laboratory and radiologic evaluations. Results: Forty-three patients were included: 70% were male; the median age was 64 years (minimummaximum: 27-94); and six (14%) patients died. The median duration of oxygen support before the onset of TCZ was shorter among the severe patient group than the critical patient group (1 vs. 4 days, p < 0.001). Three cases of 21 (14%) who received TCZ in the ward were transferred to ICU, and none of them died. The levels of IL-6, CRP, ferritin, D-dimer, and procalcitonin were significantly lower in the severe cases group than the critical cases group (p = 0.025, p = 0.002, p = 0.008, p = 0.002, and p = 0.001, respectively). Radiological improvement was observed in severe cases on the seventh day of TCZ. Secondary bacterial infection was detected in 41% of critical cases, but none of the severe ones. Conclusion: Earlier use of TCZ in COVID-19 infection was beneficial for survival, length of hospitalization and duration of oxygen support. The recommendation for administration of TCZ was based on an increase in requirement of oxygen support, progression in thoracic CT, and elevation of inflammation markers, including IL-6, CRP, ferritin, and D-dimer, and decrease in % lymphocytes.

SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital, 2018

N asal polyps (NP) are benign and are characterised by mucosal inflammation and expansion into th... more N asal polyps (NP) are benign and are characterised by mucosal inflammation and expansion into the lumen of the nasal cavity. They are typically pale grey protrusions and are induced by multifactorial causes. The prevalence in the general population ranges between 1 and 4%, and they mostly affect adult individuals. [1] These polyps have been known since ancient times, and yet the pathogenesis and treatment of NP remain to be fully elucidated. In recent years, NP has been considered to represent a subgroup of chronic sinusitis. [2] The most important factors in the development of nasal polyps are viewed as chronic inflammation and mucosal oedema. Other factors that may play a Objectives: In this study, our aim was to compare oral steroid therapy with macrolide therapy and with oral steroid + macrolide (combine) therapy in patients with nasal polyposis (NP). Methods: All patients were treated with nasal steroid therapy for eight weeks and divided randomly into three groups as follows: Oral steroid group, oral macrolide group and combine group. All patients underwent endoscopic staging, radiological grading, odour testing and completed the sino-nasal outcome test-22 (SNOT-22) questionnaire before and after treatment. Results: Significant improvement was observed in all parameters after treatment in all three groups. All parameters were significantly better in the combined group than in the macrolide group. Comparison of the oral steroid group and macrolide group revealed significantly better radiological grading and odour test changes for the oral steroid group, but no statistically significant differences existed according to endoscopic staging and SNOT-22. The post-treatment SNOT-22 score was significantly better in the combined group than in the steroid group. A comparison of the combined and steroid groups showed better results for the combined group for all parameters, but the differences were not significant. Conclusion: All treatment protocols were effective and the successful use of macrolide indicates its potential as an alternative in patients with contraindications to oral steroid treatment. The combined treatment may demonstrate significantly better results than steroid treatment alone if larger studies with more patients are performed.

SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital, 2013

Boyun ağrısında gizli tehlike: Karotidini Karotidini, karotis bifurkasyon bölgesinin palpasyon sı... more Boyun ağrısında gizli tehlike: Karotidini Karotidini, karotis bifurkasyon bölgesinin palpasyon sırasında tek taraflı hassasiyetiyle karakterize bir boyun ağrısı sendromudur. Bu sendromun doğru teşhisi için ayırıcı tanının oldukça dikkatli yapılması gerekir. Karotidini için ayırıcı tanıda, Takayasu ve temporal arteriti gibi büyük damar vaskülitleri, arterioskleroz, tromboz, fibromuskular displazi, diseksiyon ve anevrizmanın yanı sıra non-vasküler hastalıklar; lenfödem, siyaloadenit, tiroidit, peritonsiller abse veya boyun neoplazileri sayılabilir. Takayasu arteriti, etiyolojisi bilinmeyen aort ve ana dallarını tutan, nadir görülen kronik sistemik granülomatöz inflamatuar bir hastalıktır. Karotidini, Takayasu arteriti ve diğer büyük damar vaskülitlerinin klinik bir işareti olabilir. Bu çalışmada, idiopatik ve Takayasu arteritli olmak üzere iki karotidini olgusunun ultrasonografik ve manyetik rezonans bulgularını sunduk.

Ear, nose, & throat journal, 2018

The standard diagnostic tool for laryngeal paraganglioma is generally accepted to be magnetic res... more The standard diagnostic tool for laryngeal paraganglioma is generally accepted to be magnetic resonance imaging. However, the role of other imaging modalities has not been evaluated extensively. We describe the case of a 38-year-old man who had a history of voice distortion for several years. A hypervascular submucosal lesion was detected on maneuvered three-phase contrast-enhanced computed tomography (CT). The CT showed intense contrast enhancement in the first arterial phase (inspiration), a peak level in the second phase (Valsalva), and washing out in the final phase (phonation). This pattern of contrast enhancement suggested the presence of a hypervascular lesion, such as a hemangioma, paraganglioma, or vascular malformation of the larynx. We conclude that maneuvered three-phase contrast-enhanced CT may be useful for the diagnosis of paraganglioma of the larynx.

PubMed, Mar 1, 2004

The lacrimal drainage system (LDS) is vulnerable to surgical trauma during rhinoplasty. We aimed ... more The lacrimal drainage system (LDS) is vulnerable to surgical trauma during rhinoplasty. We aimed to investigate the possible effects of the low lateral osteotomies on the LDS during rhinoplasty using active transport dacryocystography (ATD) at the late postoperative stage. Twenty patients who underwent open rhinoplasty were evaluated by ATD between the sixth and seventh postoperative months. Presence of the LDS dehiscence and the absence of the passage of the contrast material into the inferior meatus were noted as signs of injury to the LDS in ATD. The proximity of the osteotomy site to the LDS was measured using three different measurements in ATD. The distance from the lacrimal fossa to the lateral osteotomy site, the distance from the inferior meatus to the lateral osteotomy site and the distance from the middle point of the lacrimal fossa and inferior meatus to the lateral osteotomy site were measured. The anatomic integrity of the bone structure around the LDS was preserved in all patients and free drainage of contrast media from the fossa lacrimalis to inferior meatus was observed in ATD evaluation of all patients. The average distance from the LDS to the lateral osteotomy site was found to be between 7-8.8 mm. In conclusion, the low lateral osteotomy is a safe method in order to avoid trauma to the LDS, and ATD seems an appropriate diagnostic technique in evaluation of the LDS after rhinoplasty.

Otology & Neurotology, Jul 1, 2012

Middle ear tumors and tumorlike structures include hemangioma, meningioma, cholesterol granuloma,... more Middle ear tumors and tumorlike structures include hemangioma, meningioma, cholesterol granuloma, primary cholesteatoma, adenomatous tumor, choristoma, and neurogenic tumors (1,2). Schwannomas are benign neurogenic tumors arising from schwann cells, which produce the myelin sheaths of peripheral nerve axons. These tumors may be seen in different locations throughout the body; when in the middle ear, they either stem from nerves of the middle ear or from neighboring tissues such as vestibular schwannomas or hypoglossal schwannomas that expand into the middle ear (3,4). Middle ear schwannomas may originate from the facial nerve, chorda tympani, auricular branch of the vagus nerve, or tympanic branch of the glossopharyngeal nerve (Jacobson’s nerve) (1,3). The most common neurogenic tumor is facial nerve schwannoma (4). In this case report, we present a middle ear mass originating from Jacobson’s nerve in a 47-year-old man; it was incidentally found during tympanomastoidectomy and was diagnosed as schwannoma.

Academic Radiology, Feb 1, 2012

Rationale and Objectives: The goal of this study is to emphasize the value of lesion-focused appr... more Rationale and Objectives: The goal of this study is to emphasize the value of lesion-focused approach in ultrasonography (US)-guided solid liver lesion biopsies performed under our guidance. Materials and Methods: In our retrospective study, after the standard preparation for US-guidance solid liver lesion biopsy was accomplished, we performed standard intercostal approach and the biopsy procedure though one of our patients experienced a major complication (pneumothorax). After this undesirable case, we reviewed our biopsy procedure and performed a lesion-focused approach technique as described in this article. A Tru-cut biopsy gun (18 gauge) was used in this trial. The liver biopsies were divided into two groups according to the biopsy technique and all results were compared with each other. Results: A total of 202 solid liver lesion biopsies were was performed under the guidance of US between October 2007 and July 2010. One major complication occurred in first group. All of the minor complications occurred in the first group. In group 2, there were no complications. For this reason, all patients in group 2 were discharged home after a few hours. Patients with minor complications in the first group were observed an average of 6 hours. Adequate tissue for pathological diagnosis was similar in both groups. Conclusion: The lesion-focused approach technique has the potential to reduce both complication rates and patient incompliance. Percutaneous liver biopsies performed with this technique using real-time US guidance are convincing and clinically beneficial.

Current Problems in Diagnostic Radiology, Jul 1, 2003

... Sinan Cakirer MD a , Corresponding Author Contact Information , E-mail The Corresponding Auth... more ... Sinan Cakirer MD a , Corresponding Author Contact Information , E-mail The Corresponding Author , Muzaffer Basak MD a , Irfan Celebi MD a , Fevziye ... Spin-echo (SE) T1-weighted images (repetition time ms/echo time ms, 430/15), fast spin echo (FSE), proton-density (PD ...

Radiologia Medica, Apr 28, 2017

Journal of Craniofacial Surgery, Mar 1, 2013

Our objective was to evaluate the relationship between subjective pulsatile tinnitus and petrous ... more Our objective was to evaluate the relationship between subjective pulsatile tinnitus and petrous bone pneumatization. Twenty-five patients admitted between January 2012 and March 2012 were assessed. The control group data were obtained by assessment of petrous bone images of 25 cases in which paranasal sinus computed tomography (CT) was performed because of chronic sinusitis and in which no ear pathology was present. Temporal bone CT images of patients with subjective pulsatile tinnitus were compared with those of patients with no ear complaints. The presence of petrous bone pneumatization was evaluated by CT. Subjective pulsatile tinnitus complaints were present for 32 of 50 ears. Pneumatization was detected in the petrous bone of 22 (68.8%) of 32 ears with subjective pulsatile tinnitus. In the control group, 25 patients (50 ears) with no ear complaints were assessed. Petrous bone pneumatization was detected in 12 (24%) of 50 ears comprising the control group. There was a statistically significant difference between the 2 groups (P = 0.000 &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001). Petrous bone pneumatization might be the cause of the subjective pulsatile tinnitus.