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Iro Savvidou

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Research paper thumbnail of Interplay between Gut Microbiome and Obesity: Insights from the Metabolic Syndrome, A Mini Review

Biomedical Journal of Scientific and Technical Research, Mar 4, 2020

Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of... more Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of the phyla firmicutes as opposed to Bacteroidetes. Which are respectfully categorized as gram-positive bacteria (GPB) and gram-negative bacteria (GNB). Their gut microbiome facilitates metabolism of substances which are otherwise indigestible to humans. Relevant literature reiterates their vital role to our daily life. Amongst individuals with metabolic disease syndrome (MetS) or/and obesity have shown to have disproportionate microbiome compared to healthy individuals. Giving rise to therapeutic options such as, prebiotics, probiotics and synbiotics as well as an educated diet. GPB, which have been shown to be a protective factor against lipopolysaccharide (LPS) induced gut-barrier dysfunctions and gut inflammation that are considered to be risk factors against MetS and obesity. In turn, the amount of GNB have a positive correlation with LPS. Relevant research supports dietary effects on microbiome and by extension on MetS and obesity. The authors acknowledge the need for more research and increased education to the general population, as well as to specialists about these implications.

Research paper thumbnail of Interplay between Gut Microbiome and Obesity: Insights from the Metabolic Syndrome, A Mini Review

Biomedical Journal of Scientific & Technical Research, 2020

Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of... more Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of the phyla firmicutes as opposed to Bacteroidetes. Which are respectfully categorized as gram-positive bacteria (GPB) and gram-negative bacteria (GNB). Their gut microbiome facilitates metabolism of substances which are otherwise indigestible to humans. Relevant literature reiterates their vital role to our daily life. Amongst individuals with metabolic disease syndrome (MetS) or/and obesity have shown to have disproportionate microbiome compared to healthy individuals. Giving rise to therapeutic options such as, prebiotics, probiotics and synbiotics as well as an educated diet. GPB, which have been shown to be a protective factor against lipopolysaccharide (LPS) induced gut-barrier dysfunctions and gut inflammation that are considered to be risk factors against MetS and obesity. In turn, the amount of GNB have a positive correlation with LPS. Relevant research supports dietary effects on microbiome and by extension on MetS and obesity. The authors acknowledge the need for more research and increased education to the general population, as well as to specialists about these implications.

Research paper thumbnail of Interplay between Gut Microbiome and Obesity: Insights from the Metabolic Syndrome, A Mini Review

Biomedical Journal of Scientific and Technical Research, Mar 4, 2020

Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of... more Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of the phyla firmicutes as opposed to Bacteroidetes. Which are respectfully categorized as gram-positive bacteria (GPB) and gram-negative bacteria (GNB). Their gut microbiome facilitates metabolism of substances which are otherwise indigestible to humans. Relevant literature reiterates their vital role to our daily life. Amongst individuals with metabolic disease syndrome (MetS) or/and obesity have shown to have disproportionate microbiome compared to healthy individuals. Giving rise to therapeutic options such as, prebiotics, probiotics and synbiotics as well as an educated diet. GPB, which have been shown to be a protective factor against lipopolysaccharide (LPS) induced gut-barrier dysfunctions and gut inflammation that are considered to be risk factors against MetS and obesity. In turn, the amount of GNB have a positive correlation with LPS. Relevant research supports dietary effects on microbiome and by extension on MetS and obesity. The authors acknowledge the need for more research and increased education to the general population, as well as to specialists about these implications.

Research paper thumbnail of Interplay between Gut Microbiome and Obesity: Insights from the Metabolic Syndrome, A Mini Review

Biomedical Journal of Scientific & Technical Research, 2020

Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of... more Humans have a symbiotic relationship with gut microbiota, normally comprised of greater amount of the phyla firmicutes as opposed to Bacteroidetes. Which are respectfully categorized as gram-positive bacteria (GPB) and gram-negative bacteria (GNB). Their gut microbiome facilitates metabolism of substances which are otherwise indigestible to humans. Relevant literature reiterates their vital role to our daily life. Amongst individuals with metabolic disease syndrome (MetS) or/and obesity have shown to have disproportionate microbiome compared to healthy individuals. Giving rise to therapeutic options such as, prebiotics, probiotics and synbiotics as well as an educated diet. GPB, which have been shown to be a protective factor against lipopolysaccharide (LPS) induced gut-barrier dysfunctions and gut inflammation that are considered to be risk factors against MetS and obesity. In turn, the amount of GNB have a positive correlation with LPS. Relevant research supports dietary effects on microbiome and by extension on MetS and obesity. The authors acknowledge the need for more research and increased education to the general population, as well as to specialists about these implications.

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