Ismail Sadek - Academia.edu (original) (raw)

Papers by Ismail Sadek

Research paper thumbnail of Study of stigma among depressed and COVID-19 infected patients

Al-Azhar International Medical Journal, 2021

Abstract: Background: Stigma is a phenomenon of underlying difficulties. It is one of the major c... more Abstract: Background: Stigma is a phenomenon of underlying difficulties. It is one of the major challenges interfering with health care services especially in the need of rapid efficient dealing like what we have in covid 19 pandemic and mental health. In our study we assessed the presence of stigma in covid 19 infected patients and depressed patients and assessed certain factors that might associated with stigmatization. Methods: The study was conducted among 70 patients; 35 patients with depression and 35 patients post COVID-19 using the Explanatory Model Interview Catalogue (EMIC) Stigma scale from outpatient psychiatric and chest clinics after verification of diagnoses. Results: The EMIC score of the studied groups showed that the mean score of depressed group is significantly higher than the mean score of covid group (28.2 ± 9.8 vs 21.7 ± 9.4, respectively). There was a non-significant negative correlation between age and stigma. Association between sex and EMIC score among t...

Research paper thumbnail of Coronary Artery Disease among Elderly Egyptian Patients: I. Socio-Demographic, Lifestyle, Psychosocial, Medical, and Biochemical Risk Factors

Background: Coronary Artery Disease (CAD) is a worldwide public health problem. Its prevalence ra... more Background: Coronary Artery Disease (CAD) is a worldwide public health problem. Its prevalence rate is increasing all over the world including Egypt. Aims: To determine the socio-demographic, lifestyle, medical and psychosocial risk factors of CAD among elderly Egyptian patients, and to determine patients’ candidates to cardiac surgery. Patients and Methods: A case-control, hospital-based study design was chosen to conduct this research. The study was conducted on 120 patients with CAD and an equal number of controls. The patients and controls were subjected to an interview, and clinical and laboratory examinations. Results: The important significant risk factors for CAD were male gender, widow/widower, high education, profession occupations, high social class, smokers, physically inactive, high fat and salt intake, hypertension, diabetes, metabolic syndrome, chronic kidney disease, obesity, abdominal obesity, family history of CAD, stress especially general stress, depression, anxi...

Research paper thumbnail of Suicidalilty in a Sample of Egyptian Adolescents with Substance Use Disorder

Al-Azhar Medical Journal, 2019

Background: Suicide is classified as the highest cause of death among young people compared to ot... more Background: Suicide is classified as the highest cause of death among young people compared to other age groups and is the second leading cause of death during childhood and adolescence. many people who have attempted suicide in their lives during their youth, the beginning of thinking about suicide and attempted suicide usually occurs before the mid-twenties. Substance use disorder and suicide usually occur among adolescents. In young people receiving treatment for substance use, 18% to 36% report a history of patients with suicidal behavior. Furthermore, adolescents diagnosed with substance use disorder were 5 to 13 times more likely to die from suicide than adolescents without this diagnosis. Objective: To find the association of suicidality among adolescents and substance use disorder. Patients and Methods: The sample consisted of 50 adolescent diagnosed with substance use disorder and 50 adolescent diagnosed with other psychiatric disorder not included substance use disorder and their age were range from 12 to 18 years old. After diagnosed clinically, according to DSM-5 through a designed semi structured interview and through application of Mini International Neuropsychiatric Interview for children and adolescents, suicidal probability scale, teen addiction severity index, and Questionnaire of parental attitudes. Results: there was a direct relationship between of addiction and susceptibility to suicide. It was found that there were statistically significant differences between the control and sample groups in terms of family history of addiction. It was found that 68% of the sample cases have a family history of addiction compared to 26% of the control and found that 32% of the sample cases have no family history of addiction compared to 74% of control. There were statistically significant differences in the sample for a major depressive episode, dysthymia, post-traumatic stress disorder, attention deficit hyperactivity disorder and generalized anxiety disorder. For the control, there were statistically significant differences for a particular phobia. There was a relationship between substance used disorder and comorbidity of psychiatric disorder. Conclusion: The results of the study showed that there was a relationship between the severity of addiction and susceptibility to suicide and that there were many psychiatric disorders associated with substance use disorder.

Research paper thumbnail of Study of Cognitive Impairment in Euthymic Bipolar Disorder Patients

The Egyptian Journal of Hospital Medicine, 2019

Background: researchers came to agreement on that bipolar disorder is commonly linked to impairme... more Background: researchers came to agreement on that bipolar disorder is commonly linked to impairment in cognitive functions by a remarkable degree. More and more evidence continue to support that the cognitive impairment remains persistent even within euthymic periods which in turn points to cognitive impairment as a possible characteristic of the disorder. Aim of the Work: objective assessment of bipolar patients' cognitive deficits present during remission and holding a Comparison of these deficits with control subjects who are completely healthy. Patients and Methods: assessing cognitive functions including executive functions, attention and memory in euthymic bipolar patients by using relevant scales, then using SPSS for comparing the results with those of a control group. Results: when compared to healthy control subjects, euthymic bipolar patients were found to exhibit a markedly noticeable impairment in attention, executive functions and total memory score. It was also noteworthy that the association between the duration of illness demonstrated through the number of episodes and the extent of impairment in cognitive functions. Conclusion: there is an apparent association of bipolar disorder with cognitive impairment even when patients are in euthymic state and consequently, the number of episodes increases the impairment degree.

Research paper thumbnail of Study of Depression in Attention Deficit Hyperactive Disorder Subtypes in sample of children patients

Al-Azhar International Medical Journal

Background: Attention deficit hyperactivity disorder (ADHD) has three subtypes : hyperactive, ina... more Background: Attention deficit hyperactivity disorder (ADHD) has three subtypes : hyperactive, inattentive and mixed types each of them has role in development and presence of depression. Aim of work: To detect the association between each subtype and presences of depressive disorder. Patient and Methods: This study comparative study done on ADHD patients took place at the outpatient child and adolescent psychiatric clinic at Al-Hussien University Hospital in Cairo, were recruited from January to June 2017. The children was assessed at first by Psychiatric semi-structured clinical interview then Complete medical and neurological examination, The Arabic version of MINI Kid were applied on children with ADHD. Results: The total sample size at time of study was 96 child only 64 child which fit the inclusion criteria then they divided into three groups depending on the type of ADHD according to mini kid scale. Group 1 hyperactive type was 18.7%, Group 2 inattentive type was 56.3% and Group 3 mixed type was 25%. Male sex was more predominant, depression was more prevalent in inattentive type of ADHD in all the sample while inside each group depressed patients present in hyperactive group more than non-depressed patients. There was positive correlation between age and presence of depression in hyperactive type, while there was a negative correlation with the other two groups. Conclusion: ADHD subtypes affect development of depression as found that The inattentive participants more susceptible for depression. Moreover, Age may be risk factor for depression in hyperactive type.

Research paper thumbnail of Study of EEG Changes Among Sample Of Egyptian Children With Attention Deficit Hyperactivity Disorder

Al-Azhar International Medical Journal

Background: Attention Deficit Hyperactivity Disorder(ADHD) is a mental Neuro-developmental type, ... more Background: Attention Deficit Hyperactivity Disorder(ADHD) is a mental Neuro-developmental type, Up to 5% of primary school-age children have ADHD, characterized by Inattention, Hyperactivity ,and Impulsivity, Relation between Encephalography (EEG) and (ADHD) is ambiguous, Guidelines recommend that (EEG) indicated only in the clinical suggestions of seizure disorder or a presence of focal signs. Aim of The Work: To Study the prevalence of presence of changes in EEG recording of children diagnosed with different type of ADHD between (ADHD) children and their (EEG) changes, Further study of the Efficacy of Atomoxetine\Antipsychotic and Antiepileptic on ADHD children. Patient and Methods: 60 Egyptian child (age 6-18) diagnosed with ADHD with No previous history of seizures. They have been attending to Police Academy Hospital, Neuropsychiatry clinic for treatment and fulfilling the criteria for (ADHD) according to (DSM-IV), All patient was assessed with Conner's scale for (ADHD) and (EEG) was applied for 60 children. Follow up study was conducted from September 2018 to January 2021, included, Follow up assessment for 18 months from January 2019 to June 2020 of all children with their treatment of all types of (ADHD) using Atomoxetine, Atomoxetine/Antipsychotic combination ,and Antiepileptic. Results: Out of 60(ADHD) children, only 6 children (10%) (1 patient with Hyperactivity type, 2 patients with inattention type and 3 patients with combined type) showed (EEG) Abnormalities, Antiepileptic was given for all the (6) patient regardless their ADHD type, weak improvement on (1 out of 6) with only (16.7% .) Atomoxetine only was given to (27) child and showed a modest efficacy on (12 out of 27) patient with (44.4%) for all ADHD children regardless their type, While it showed a noticeable improvement on ADHD inattention type on (4 out of 4) with (100% .) Atomoxetine\Antipsychotic combination was given to (27) child and showed a superior efficacy on (24 out of 27) patient with (88.9%) for all ADHD children regardless their type, While it showed a noticeable improvement on ADHD hyperactivity type on (9 out of 9) with (100%). Conclusion: There was a weak correlation of EEG changes and diagnosis of ADHD in children, beside that there was a weak role of Antiepileptic compared to other drugs.

Research paper thumbnail of Study of stigma among depressed and COVID-19 infected patients

Al-Azhar International Medical Journal, 2021

Abstract: Background: Stigma is a phenomenon of underlying difficulties. It is one of the major c... more Abstract: Background: Stigma is a phenomenon of underlying difficulties. It is one of the major challenges interfering with health care services especially in the need of rapid efficient dealing like what we have in covid 19 pandemic and mental health. In our study we assessed the presence of stigma in covid 19 infected patients and depressed patients and assessed certain factors that might associated with stigmatization. Methods: The study was conducted among 70 patients; 35 patients with depression and 35 patients post COVID-19 using the Explanatory Model Interview Catalogue (EMIC) Stigma scale from outpatient psychiatric and chest clinics after verification of diagnoses. Results: The EMIC score of the studied groups showed that the mean score of depressed group is significantly higher than the mean score of covid group (28.2 ± 9.8 vs 21.7 ± 9.4, respectively). There was a non-significant negative correlation between age and stigma. Association between sex and EMIC score among t...

Research paper thumbnail of Coronary Artery Disease among Elderly Egyptian Patients: I. Socio-Demographic, Lifestyle, Psychosocial, Medical, and Biochemical Risk Factors

Background: Coronary Artery Disease (CAD) is a worldwide public health problem. Its prevalence ra... more Background: Coronary Artery Disease (CAD) is a worldwide public health problem. Its prevalence rate is increasing all over the world including Egypt. Aims: To determine the socio-demographic, lifestyle, medical and psychosocial risk factors of CAD among elderly Egyptian patients, and to determine patients’ candidates to cardiac surgery. Patients and Methods: A case-control, hospital-based study design was chosen to conduct this research. The study was conducted on 120 patients with CAD and an equal number of controls. The patients and controls were subjected to an interview, and clinical and laboratory examinations. Results: The important significant risk factors for CAD were male gender, widow/widower, high education, profession occupations, high social class, smokers, physically inactive, high fat and salt intake, hypertension, diabetes, metabolic syndrome, chronic kidney disease, obesity, abdominal obesity, family history of CAD, stress especially general stress, depression, anxi...

Research paper thumbnail of Suicidalilty in a Sample of Egyptian Adolescents with Substance Use Disorder

Al-Azhar Medical Journal, 2019

Background: Suicide is classified as the highest cause of death among young people compared to ot... more Background: Suicide is classified as the highest cause of death among young people compared to other age groups and is the second leading cause of death during childhood and adolescence. many people who have attempted suicide in their lives during their youth, the beginning of thinking about suicide and attempted suicide usually occurs before the mid-twenties. Substance use disorder and suicide usually occur among adolescents. In young people receiving treatment for substance use, 18% to 36% report a history of patients with suicidal behavior. Furthermore, adolescents diagnosed with substance use disorder were 5 to 13 times more likely to die from suicide than adolescents without this diagnosis. Objective: To find the association of suicidality among adolescents and substance use disorder. Patients and Methods: The sample consisted of 50 adolescent diagnosed with substance use disorder and 50 adolescent diagnosed with other psychiatric disorder not included substance use disorder and their age were range from 12 to 18 years old. After diagnosed clinically, according to DSM-5 through a designed semi structured interview and through application of Mini International Neuropsychiatric Interview for children and adolescents, suicidal probability scale, teen addiction severity index, and Questionnaire of parental attitudes. Results: there was a direct relationship between of addiction and susceptibility to suicide. It was found that there were statistically significant differences between the control and sample groups in terms of family history of addiction. It was found that 68% of the sample cases have a family history of addiction compared to 26% of the control and found that 32% of the sample cases have no family history of addiction compared to 74% of control. There were statistically significant differences in the sample for a major depressive episode, dysthymia, post-traumatic stress disorder, attention deficit hyperactivity disorder and generalized anxiety disorder. For the control, there were statistically significant differences for a particular phobia. There was a relationship between substance used disorder and comorbidity of psychiatric disorder. Conclusion: The results of the study showed that there was a relationship between the severity of addiction and susceptibility to suicide and that there were many psychiatric disorders associated with substance use disorder.

Research paper thumbnail of Study of Cognitive Impairment in Euthymic Bipolar Disorder Patients

The Egyptian Journal of Hospital Medicine, 2019

Background: researchers came to agreement on that bipolar disorder is commonly linked to impairme... more Background: researchers came to agreement on that bipolar disorder is commonly linked to impairment in cognitive functions by a remarkable degree. More and more evidence continue to support that the cognitive impairment remains persistent even within euthymic periods which in turn points to cognitive impairment as a possible characteristic of the disorder. Aim of the Work: objective assessment of bipolar patients' cognitive deficits present during remission and holding a Comparison of these deficits with control subjects who are completely healthy. Patients and Methods: assessing cognitive functions including executive functions, attention and memory in euthymic bipolar patients by using relevant scales, then using SPSS for comparing the results with those of a control group. Results: when compared to healthy control subjects, euthymic bipolar patients were found to exhibit a markedly noticeable impairment in attention, executive functions and total memory score. It was also noteworthy that the association between the duration of illness demonstrated through the number of episodes and the extent of impairment in cognitive functions. Conclusion: there is an apparent association of bipolar disorder with cognitive impairment even when patients are in euthymic state and consequently, the number of episodes increases the impairment degree.

Research paper thumbnail of Study of Depression in Attention Deficit Hyperactive Disorder Subtypes in sample of children patients

Al-Azhar International Medical Journal

Background: Attention deficit hyperactivity disorder (ADHD) has three subtypes : hyperactive, ina... more Background: Attention deficit hyperactivity disorder (ADHD) has three subtypes : hyperactive, inattentive and mixed types each of them has role in development and presence of depression. Aim of work: To detect the association between each subtype and presences of depressive disorder. Patient and Methods: This study comparative study done on ADHD patients took place at the outpatient child and adolescent psychiatric clinic at Al-Hussien University Hospital in Cairo, were recruited from January to June 2017. The children was assessed at first by Psychiatric semi-structured clinical interview then Complete medical and neurological examination, The Arabic version of MINI Kid were applied on children with ADHD. Results: The total sample size at time of study was 96 child only 64 child which fit the inclusion criteria then they divided into three groups depending on the type of ADHD according to mini kid scale. Group 1 hyperactive type was 18.7%, Group 2 inattentive type was 56.3% and Group 3 mixed type was 25%. Male sex was more predominant, depression was more prevalent in inattentive type of ADHD in all the sample while inside each group depressed patients present in hyperactive group more than non-depressed patients. There was positive correlation between age and presence of depression in hyperactive type, while there was a negative correlation with the other two groups. Conclusion: ADHD subtypes affect development of depression as found that The inattentive participants more susceptible for depression. Moreover, Age may be risk factor for depression in hyperactive type.

Research paper thumbnail of Study of EEG Changes Among Sample Of Egyptian Children With Attention Deficit Hyperactivity Disorder

Al-Azhar International Medical Journal

Background: Attention Deficit Hyperactivity Disorder(ADHD) is a mental Neuro-developmental type, ... more Background: Attention Deficit Hyperactivity Disorder(ADHD) is a mental Neuro-developmental type, Up to 5% of primary school-age children have ADHD, characterized by Inattention, Hyperactivity ,and Impulsivity, Relation between Encephalography (EEG) and (ADHD) is ambiguous, Guidelines recommend that (EEG) indicated only in the clinical suggestions of seizure disorder or a presence of focal signs. Aim of The Work: To Study the prevalence of presence of changes in EEG recording of children diagnosed with different type of ADHD between (ADHD) children and their (EEG) changes, Further study of the Efficacy of Atomoxetine\Antipsychotic and Antiepileptic on ADHD children. Patient and Methods: 60 Egyptian child (age 6-18) diagnosed with ADHD with No previous history of seizures. They have been attending to Police Academy Hospital, Neuropsychiatry clinic for treatment and fulfilling the criteria for (ADHD) according to (DSM-IV), All patient was assessed with Conner's scale for (ADHD) and (EEG) was applied for 60 children. Follow up study was conducted from September 2018 to January 2021, included, Follow up assessment for 18 months from January 2019 to June 2020 of all children with their treatment of all types of (ADHD) using Atomoxetine, Atomoxetine/Antipsychotic combination ,and Antiepileptic. Results: Out of 60(ADHD) children, only 6 children (10%) (1 patient with Hyperactivity type, 2 patients with inattention type and 3 patients with combined type) showed (EEG) Abnormalities, Antiepileptic was given for all the (6) patient regardless their ADHD type, weak improvement on (1 out of 6) with only (16.7% .) Atomoxetine only was given to (27) child and showed a modest efficacy on (12 out of 27) patient with (44.4%) for all ADHD children regardless their type, While it showed a noticeable improvement on ADHD inattention type on (4 out of 4) with (100% .) Atomoxetine\Antipsychotic combination was given to (27) child and showed a superior efficacy on (24 out of 27) patient with (88.9%) for all ADHD children regardless their type, While it showed a noticeable improvement on ADHD hyperactivity type on (9 out of 9) with (100%). Conclusion: There was a weak correlation of EEG changes and diagnosis of ADHD in children, beside that there was a weak role of Antiepileptic compared to other drugs.