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Papers by Ivete Mendonca

Research paper thumbnail of Easy test for visceral Leishmaniasis and post-Kala-azar Dermal Leishmaniasis

Emerging infectious diseases, 2011

Samiran Saha, 1 Ramaprasad Goswami, Netai Pramanik, Subhasis K. Guha, Bibhuti Saha, Mehebubar Rah... more Samiran Saha, 1 Ramaprasad Goswami, Netai Pramanik, Subhasis K. Guha, Bibhuti Saha, Mehebubar Rahman, Sudeshna Mallick, Dolanchampa Modak, Fernando O. Silva, Ivete L. Mendonca, Dorcas L. Costa, Carlos HN Costa, and Nahid Ali Comments to Author

Research paper thumbnail of Infecção natural de Lutzomyia longipalpis por Leishmania sp. em Teresina, Piauí, Brasil

Cadernos de Saúde Pública, 2007

Research paper thumbnail of Recombinant Cysteine Proteinase from Leishmania (Leishmania) chagasi Implicated in Human and Dog T-Cell Responses

Infection and Immunity, 2005

Received 20 October 2004/Returned for modification 8 December 2004/Accepted 20 January 2005 High ... more Received 20 October 2004/Returned for modification 8 December 2004/Accepted 20 January 2005 High in vitro lymphoproliferative responses were induced in humans and dogs by a recombinant Leishmania (Leishmania) chagasi cysteine proteinase, with secretion of IFN- in asymptomatic subjects or of IFN-, interleukin 4 (IL-4), and IL-10 in oligosymptomatic subjects. In contrast, responses of symptomatic patients and dogs were lower, with

Research paper thumbnail of Recombinant Cysteine Proteinase from Leishmania (Leishmania) chagasi Implicated in Human and Dog T-Cell Responses

Infection and Immunity, 2005

FIG. 2. NO production. PBMC isolated from human (A) and dog (B) blood were cultured for 72 h in t... more FIG. 2. NO production. PBMC isolated from human (A) and dog (B) blood were cultured for 72 h in the presence of 2.5 g/ml rLdccys1, and NO was assayed in the cellular supernatants as described previously. Results are shown as the means Ϯ standard deviations and are representative of three experiments.

Research paper thumbnail of Transmission potential, skin inflammatory response, and parasitism of symptomatic and asymptomatic dogs with visceral leishmaniasis

BMC Veterinary Research, 2008

Background: Visceral leishmaniasis in Brazil is caused by the protozoan Leishmania (Leishmania) c... more Background: Visceral leishmaniasis in Brazil is caused by the protozoan Leishmania (Leishmania) chagasi and it is transmitted by sandfly of the genus Lutzomyia. Dogs are an important domestic reservoir, and control of the transmission of visceral leishmaniasis (VL) to humans includes the elimination of infected dogs. However, though dogs are considered to be an important element in the transmission cycle of Leishmania, the identification of infected dogs representing an immediate risk for transmission has not been properly evaluated. Since it is not possible to treat infected dogs, they are sacrificed when a diagnosis of VL is established, a measure that is difficult to accomplish in highly endemic areas. In such areas, parameters that allow for easy identification of reservoirs that represents an immediate risk for transmission is of great importance for the control of VL transmission. In this study we aimed to identify clinical parameters, reinforced by pathological parameters that characterize dogs with potential to transmit the parasite to the vector.

Research paper thumbnail of Discovery of Markers of Exposure Specific to Bites of Lutzomyia longipalpis, the Vector of Leishmania infantum chagasi in Latin America

PLoS Neglected Tropical Diseases, 2010

Background: Sand flies deliver Leishmania parasites to a host alongside salivary molecules that a... more Background: Sand flies deliver Leishmania parasites to a host alongside salivary molecules that affect infection outcomes. Though some proteins are immunogenic and have potential as markers of vector exposure, their identity and vector specificity remain elusive.

Research paper thumbnail of Easy test for visceral Leishmaniasis and post-Kala-azar Dermal Leishmaniasis

Emerging infectious diseases, 2011

Samiran Saha, 1 Ramaprasad Goswami, Netai Pramanik, Subhasis K. Guha, Bibhuti Saha, Mehebubar Rah... more Samiran Saha, 1 Ramaprasad Goswami, Netai Pramanik, Subhasis K. Guha, Bibhuti Saha, Mehebubar Rahman, Sudeshna Mallick, Dolanchampa Modak, Fernando O. Silva, Ivete L. Mendonca, Dorcas L. Costa, Carlos HN Costa, and Nahid Ali Comments to Author

Research paper thumbnail of Infecção natural de Lutzomyia longipalpis por Leishmania sp. em Teresina, Piauí, Brasil

Cadernos de Saúde Pública, 2007

Research paper thumbnail of Recombinant Cysteine Proteinase from Leishmania (Leishmania) chagasi Implicated in Human and Dog T-Cell Responses

Infection and Immunity, 2005

Received 20 October 2004/Returned for modification 8 December 2004/Accepted 20 January 2005 High ... more Received 20 October 2004/Returned for modification 8 December 2004/Accepted 20 January 2005 High in vitro lymphoproliferative responses were induced in humans and dogs by a recombinant Leishmania (Leishmania) chagasi cysteine proteinase, with secretion of IFN- in asymptomatic subjects or of IFN-, interleukin 4 (IL-4), and IL-10 in oligosymptomatic subjects. In contrast, responses of symptomatic patients and dogs were lower, with

Research paper thumbnail of Recombinant Cysteine Proteinase from Leishmania (Leishmania) chagasi Implicated in Human and Dog T-Cell Responses

Infection and Immunity, 2005

FIG. 2. NO production. PBMC isolated from human (A) and dog (B) blood were cultured for 72 h in t... more FIG. 2. NO production. PBMC isolated from human (A) and dog (B) blood were cultured for 72 h in the presence of 2.5 g/ml rLdccys1, and NO was assayed in the cellular supernatants as described previously. Results are shown as the means Ϯ standard deviations and are representative of three experiments.

Research paper thumbnail of Transmission potential, skin inflammatory response, and parasitism of symptomatic and asymptomatic dogs with visceral leishmaniasis

BMC Veterinary Research, 2008

Background: Visceral leishmaniasis in Brazil is caused by the protozoan Leishmania (Leishmania) c... more Background: Visceral leishmaniasis in Brazil is caused by the protozoan Leishmania (Leishmania) chagasi and it is transmitted by sandfly of the genus Lutzomyia. Dogs are an important domestic reservoir, and control of the transmission of visceral leishmaniasis (VL) to humans includes the elimination of infected dogs. However, though dogs are considered to be an important element in the transmission cycle of Leishmania, the identification of infected dogs representing an immediate risk for transmission has not been properly evaluated. Since it is not possible to treat infected dogs, they are sacrificed when a diagnosis of VL is established, a measure that is difficult to accomplish in highly endemic areas. In such areas, parameters that allow for easy identification of reservoirs that represents an immediate risk for transmission is of great importance for the control of VL transmission. In this study we aimed to identify clinical parameters, reinforced by pathological parameters that characterize dogs with potential to transmit the parasite to the vector.

Research paper thumbnail of Discovery of Markers of Exposure Specific to Bites of Lutzomyia longipalpis, the Vector of Leishmania infantum chagasi in Latin America

PLoS Neglected Tropical Diseases, 2010

Background: Sand flies deliver Leishmania parasites to a host alongside salivary molecules that a... more Background: Sand flies deliver Leishmania parasites to a host alongside salivary molecules that affect infection outcomes. Though some proteins are immunogenic and have potential as markers of vector exposure, their identity and vector specificity remain elusive.

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