Ivie Paula - Academia.edu (original) (raw)
Papers by Ivie Paula
Revista Da Sociedade Brasileira De Medicina Tropical, Sep 24, 2012
Journal of Breast Imaging, 2021
Objective To compare the intratumoral T2 signal intensity on MRI and histopathological and molecu... more Objective To compare the intratumoral T2 signal intensity on MRI and histopathological and molecular expression of biomarkers of aggressiveness (histological grade, hormonal status, HER2, and Ki-67). Methods This retrospective study included all women with invasive breast cancer undergoing MRI from January 2014 to October 2016. The intratumoral T2 signal as interpreted at consensus by two radiologists was compared to histopathological and molecular prognostic factors from the surgical specimen. Statistical analyses used Pearson χ 2 test with a confidence level of 95% (P ≤ 0.05). Results Fifty patients with 50 lesions met study criteria (mean age 65.8 ± 13.5 years). Mean lesion size was 28 mm ± 15.7 mm (range, 15 to 76 mm). Cancer types were invasive ductal (35/50, 70%), invasive lobular (10/50, 20%), and mixed (5/50, 10%). Most lesions were histological grade 1 or 2 (41/50, 82%) and luminal type (45/50, 90%). On T2 images, lesions were hypointense in 62% (31/50), isointense in 20% (...
Radiologia Brasileira, 2017
Nipple discharge is a common symptom in clinical practice, representing the third leading breast ... more Nipple discharge is a common symptom in clinical practice, representing the third leading breast complaint, after pain and lumps. It is usually limited and has a benign etiology. The risk of malignancy is higher when the discharge is uniductal, unilateral, spontaneous, persistent, bloody, or serous, as well as when it is accompanied by a breast mass. The most common causes of pathologic nipple discharge are papilloma and ductal ectasia. However, there is a 5% risk of malignancy, mainly ductal carcinoma in situ. The clinical examination is an essential part of the patient evaluation, allowing benign nipple discharge to be distinguished from suspicious nipple discharge, which calls for imaging. Mammography and ultrasound should be used together as first-line imaging methods. However, mammography has low sensitivity in cases of nipple discharge, because, typically, the lesions are small, are retroareolar, and contain no calcifications. Because the reported sensitivity and specificity o...
Revista da Associação Médica de Minas Gerais
Revista da Sociedade Brasileira de Medicina Tropical, 2012
INTRODUCTION: There is no study relating magnetic resonance imaging (MRI) to ultrasound (US) find... more INTRODUCTION: There is no study relating magnetic resonance imaging (MRI) to ultrasound (US) findings in patients with Schistosomiasis mansoni. Our aim was to describe MRI findings inpatients with schistosomal liver disease identified by US. METHODS: Fifty-four patients (mean age 41.6±13.5years) from an area endemic for Schistosomiasis mansoni were selected for this study.All had US indicating liver schistosomal fibrosis and were evaluated with MRI performed witha 1.5-T superconducting magnet unit (Sigma). RESULTS: Forty-seven (87%) of the 54 patientsshowing signs of periportal fibrosis identified through US investigation had confirmed diagnosesby MRI. In the seven discordant cases (13%), MRI revealed fat tissue filling in the hilar periportalspace where US indicated isolated thickening around the main portal vein at its point of entryto the liver. We named this the fatty hilum sign. One of the 47 patients with MRI evidence ofperiportal fibrosis had had his gallbladder removed previ...
Revista Médica de Minas Gerais, 2014
The diagnosis of paracoccidioidomycosis requires epidemiological data to be available and for the... more The diagnosis of paracoccidioidomycosis requires epidemiological data to be available and for the presence of some more typical clinical manifestations.It requires complementary investigation with interventional methods, differential diagnosis of pathologies of great importance such as tuberculosis and lymphomas, and cure control. This update discusses the advances in these various areas, which include complementary investigation, differential diagnosis and cure control, pointing to development prospects that may help better define the best approach to this disease.
Revista Médica de Minas Gerais, 2014
A paracoccidioidomicose possui clínica polimórfica, com manifestações localizadas em pele e mucos... more A paracoccidioidomicose possui clínica polimórfica, com manifestações localizadas em pele e mucosas até comprometimento de vários órgãos e sistemas, potencialmente capaz de provocar sequelas graves e morte. Deve ser incluída no diagnóstico diferencial das doenças granulomatosas, em áreas endêmicas, como ocorre no Brasil, para que seja reconhecida com precocidade, tratada convenientemente e evitada sua evolução para sequelas e morte prematura.
Mycopathologia, 2005
The lymphoabdominal involvement in the sub-acute form of paracoccidioidomycosis shows a wide vari... more The lymphoabdominal involvement in the sub-acute form of paracoccidioidomycosis shows a wide variety of clinical manifestations, ranging from fever and lymph node enlargement to infiltration of all abdominal organs, which can lead to a situation of abdominal surgical emergency. This case report presents paracoccidioidomycosis mimicking carcinoma of the biliary tract, The purpose of this paper is to call the general physician's attention for this important differential diagnosis of abdominal masses. Although paracoccidioidomycosis is rarely encountered in the United States and Europe, it should be considered in patients who are suspected of having a fungal infection and have had previous exposure in an endemic area for this disease.
Mycopathologia, 2005
Expression of capsule-associated genes of Cryptococcus neoformans – Ken Okabayashi, Rui Kano, Shi... more Expression of capsule-associated genes of Cryptococcus neoformans – Ken Okabayashi, Rui Kano, Shinichi Watanabe & Atsuhiko Hasegawa 1–7 DNA fingerprinting pattern and susceptibility to antifungal drugs in Cryptococcus neoformans variety grubii isolates from Barcelona city and rural environmental samples – Yolanda Morera-López, Josep Maria Torres-Rodrı́guez, Teresa Jiménez-Cabello, Teresa Baró-Tomás, Concepción Alı́a-Aponte & Marcia S. Lázera 9–14 Nocardia cyriacigeorgica is a significant pathogen responsible for nocardiosis in Japan and Thailand – Akiko Kageyama, Yasutaka Hoshino, Katsukiyo Yazawa, Natteewan Poonwan, Nobuyoshi Takeshita, Satoshi Maki & Yuzuru Mikami 15–19 A study of dermatophytosis in South West of Iran (Ahwaz) – Ali Zarei Mahmoudabadi 21–24 Lymphoabdominal paracoccidioidomycosis simulating primary neoplasia of the biliary tract – Fábio Luis Silva do Prado, Renata Prado, Cecı́lia Campos Valadares Gontijo, Ricardo Miguel Costa de Freitas, Maria Clara Nunes Pereira, Ivie Braga de Paula & Enio Roberto Pietra Pedroso 25–28
Gastrointestinal Radiology, 1990
... Carlo Fugazzola, 1 Carlo Procacci, 1 Ivo Andrea Bergamo Andreis, 1 Calogero Iacono, 2 Antonel... more ... Carlo Fugazzola, 1 Carlo Procacci, 1 Ivo Andrea Bergamo Andreis, 1 Calogero Iacono, 2 Antonella Portuese, ~ Giancarlo Mansueto, a Elena Residori ... In: Riz-zatto G, Solbiati L, Derchi L, Busilacehi P (eds): Imaging-US, A vanzamenti '88, Milano: Masson, 1989, pp 119-129 29. ...
Archives of Breast Cancer
Background: Autoimmune/inflammatory syndrome (ASIA) constitutes a set of related immune mediated ... more Background: Autoimmune/inflammatory syndrome (ASIA) constitutes a set of related immune mediated diseases that share a common clinical picture and a history of a previous exposure to an adjuvant agent. From a clinical standpoint, patients present with none specific manifestations such as myalgia, arthralgia, chronic fatigue and dry mouth as well as neurological manifestations such as cognitive disturbances, memory loss and neurologic disabilities. .Case presentation: A previously healthy 25-year-old patient who underwent breast augmentation 3 years ago, with an asymptomatic rupture of the silicone breast implant, presented with three major criteria of ASIA, and improved after bilateral implant removal. She also had pleuritis and pericarditis, rarely described in such disease. A literature review on complications related to breast implants, their questionable relationship to the onset of autoimmune pathologies, and basic aspects of the diagnosis and management of ASIA was carried out...
Radiologia Brasileira
OBJETIVO: Avaliar e discutir as indicações de ressonância magnética das mamas em um centro de ref... more OBJETIVO: Avaliar e discutir as indicações de ressonância magnética das mamas em um centro de referência oncológico. MATERIAIS E MÉTODOS: Estudo retrospectivo, aprovado pelo Comitê de Ética e Pesquisa da instituição, conduzido através da revisão de prontuários e laudos médicos. Foram incluídos todos os exames de ressonância magnética das mamas realizados no período de julho de 2008 a julho de 2009 (n = 529). RESULTADOS: A idade média das pacientes foi de 49 anos, variando de 17 a 86 anos. História familiar de câncer de mama e/ou ovário esteve presente em 162 pacientes (30,6%). As indicações mais comuns de ressonância magnética das mamas foram esclarecimento de achados inconclusivos na mamografia e/ou ultrassom (48,8%), avaliação de recorrência tumoral/cicatriz cirúrgica (15,1%), estadiamento/planejamento cirúrgico (11,7%) e rastreamento de pacientes de alto risco (8,5%). CONCLUSÃO: Apesar de achados inconclusivos nos exames convencionais serem a indicação mais comum de ressonância m...
Revista da Sociedade …, 2010
Introduction: The purpose of this study was to compare respiratory signs and symptoms between pat... more Introduction: The purpose of this study was to compare respiratory signs and symptoms between patients with and without chest X-ray abnormalities in order to establish the meaning of radiographic findings in pulmonary PCM diagnosis. Methods: The epidemiological, clinical and radiological lung findings of 44 patients with paracoccidiodomycosis (PCM) were evaluated. Patients were divided into two groups of 23 and 21 individuals according to the presence (group 1) or absence (group 2) of chest X-ray abnormalities, respectively, and their clinical data was analyzed with the aid of statistical tools. Results: As a general rule, patients were rural workers, young adult males and smokers-group 1 and 2, respectively: males (91.3% and 66.7%); mean age (44.4 and 27.9 year-old); smoking (34.7% and 71.4 %); acute/subacute presentation (38.1% and 21.7%); chronic presentation (61.9% and 78.3%). The most frequent respiratory manifestations were-group 1 and 2, respectively: cough (25% and 11.4%) and dyspnea (22.7% and 6.8%). No statistical difference was observed in pulmonary signs and symptoms between patients with or without radiographic abnormalities. The most frequent radiological finding was nodular (23.8%) or nodular-fibrous (19%), bilateral (90.5%) and diffuse infiltrates (85.7%). Conclusions: Absence of statistical difference in pulmonary signs and symptoms between these two groups of patients with PCM indicates clinical-radiological dissociation. A simplified classification of radiological lung PCM findings is suggested, based on correlation of these data and current literature review.
Revista Da Sociedade Brasileira De Medicina Tropical, Sep 24, 2012
Journal of Breast Imaging, 2021
Objective To compare the intratumoral T2 signal intensity on MRI and histopathological and molecu... more Objective To compare the intratumoral T2 signal intensity on MRI and histopathological and molecular expression of biomarkers of aggressiveness (histological grade, hormonal status, HER2, and Ki-67). Methods This retrospective study included all women with invasive breast cancer undergoing MRI from January 2014 to October 2016. The intratumoral T2 signal as interpreted at consensus by two radiologists was compared to histopathological and molecular prognostic factors from the surgical specimen. Statistical analyses used Pearson χ 2 test with a confidence level of 95% (P ≤ 0.05). Results Fifty patients with 50 lesions met study criteria (mean age 65.8 ± 13.5 years). Mean lesion size was 28 mm ± 15.7 mm (range, 15 to 76 mm). Cancer types were invasive ductal (35/50, 70%), invasive lobular (10/50, 20%), and mixed (5/50, 10%). Most lesions were histological grade 1 or 2 (41/50, 82%) and luminal type (45/50, 90%). On T2 images, lesions were hypointense in 62% (31/50), isointense in 20% (...
Radiologia Brasileira, 2017
Nipple discharge is a common symptom in clinical practice, representing the third leading breast ... more Nipple discharge is a common symptom in clinical practice, representing the third leading breast complaint, after pain and lumps. It is usually limited and has a benign etiology. The risk of malignancy is higher when the discharge is uniductal, unilateral, spontaneous, persistent, bloody, or serous, as well as when it is accompanied by a breast mass. The most common causes of pathologic nipple discharge are papilloma and ductal ectasia. However, there is a 5% risk of malignancy, mainly ductal carcinoma in situ. The clinical examination is an essential part of the patient evaluation, allowing benign nipple discharge to be distinguished from suspicious nipple discharge, which calls for imaging. Mammography and ultrasound should be used together as first-line imaging methods. However, mammography has low sensitivity in cases of nipple discharge, because, typically, the lesions are small, are retroareolar, and contain no calcifications. Because the reported sensitivity and specificity o...
Revista da Associação Médica de Minas Gerais
Revista da Sociedade Brasileira de Medicina Tropical, 2012
INTRODUCTION: There is no study relating magnetic resonance imaging (MRI) to ultrasound (US) find... more INTRODUCTION: There is no study relating magnetic resonance imaging (MRI) to ultrasound (US) findings in patients with Schistosomiasis mansoni. Our aim was to describe MRI findings inpatients with schistosomal liver disease identified by US. METHODS: Fifty-four patients (mean age 41.6±13.5years) from an area endemic for Schistosomiasis mansoni were selected for this study.All had US indicating liver schistosomal fibrosis and were evaluated with MRI performed witha 1.5-T superconducting magnet unit (Sigma). RESULTS: Forty-seven (87%) of the 54 patientsshowing signs of periportal fibrosis identified through US investigation had confirmed diagnosesby MRI. In the seven discordant cases (13%), MRI revealed fat tissue filling in the hilar periportalspace where US indicated isolated thickening around the main portal vein at its point of entryto the liver. We named this the fatty hilum sign. One of the 47 patients with MRI evidence ofperiportal fibrosis had had his gallbladder removed previ...
Revista Médica de Minas Gerais, 2014
The diagnosis of paracoccidioidomycosis requires epidemiological data to be available and for the... more The diagnosis of paracoccidioidomycosis requires epidemiological data to be available and for the presence of some more typical clinical manifestations.It requires complementary investigation with interventional methods, differential diagnosis of pathologies of great importance such as tuberculosis and lymphomas, and cure control. This update discusses the advances in these various areas, which include complementary investigation, differential diagnosis and cure control, pointing to development prospects that may help better define the best approach to this disease.
Revista Médica de Minas Gerais, 2014
A paracoccidioidomicose possui clínica polimórfica, com manifestações localizadas em pele e mucos... more A paracoccidioidomicose possui clínica polimórfica, com manifestações localizadas em pele e mucosas até comprometimento de vários órgãos e sistemas, potencialmente capaz de provocar sequelas graves e morte. Deve ser incluída no diagnóstico diferencial das doenças granulomatosas, em áreas endêmicas, como ocorre no Brasil, para que seja reconhecida com precocidade, tratada convenientemente e evitada sua evolução para sequelas e morte prematura.
Mycopathologia, 2005
The lymphoabdominal involvement in the sub-acute form of paracoccidioidomycosis shows a wide vari... more The lymphoabdominal involvement in the sub-acute form of paracoccidioidomycosis shows a wide variety of clinical manifestations, ranging from fever and lymph node enlargement to infiltration of all abdominal organs, which can lead to a situation of abdominal surgical emergency. This case report presents paracoccidioidomycosis mimicking carcinoma of the biliary tract, The purpose of this paper is to call the general physician's attention for this important differential diagnosis of abdominal masses. Although paracoccidioidomycosis is rarely encountered in the United States and Europe, it should be considered in patients who are suspected of having a fungal infection and have had previous exposure in an endemic area for this disease.
Mycopathologia, 2005
Expression of capsule-associated genes of Cryptococcus neoformans – Ken Okabayashi, Rui Kano, Shi... more Expression of capsule-associated genes of Cryptococcus neoformans – Ken Okabayashi, Rui Kano, Shinichi Watanabe & Atsuhiko Hasegawa 1–7 DNA fingerprinting pattern and susceptibility to antifungal drugs in Cryptococcus neoformans variety grubii isolates from Barcelona city and rural environmental samples – Yolanda Morera-López, Josep Maria Torres-Rodrı́guez, Teresa Jiménez-Cabello, Teresa Baró-Tomás, Concepción Alı́a-Aponte & Marcia S. Lázera 9–14 Nocardia cyriacigeorgica is a significant pathogen responsible for nocardiosis in Japan and Thailand – Akiko Kageyama, Yasutaka Hoshino, Katsukiyo Yazawa, Natteewan Poonwan, Nobuyoshi Takeshita, Satoshi Maki & Yuzuru Mikami 15–19 A study of dermatophytosis in South West of Iran (Ahwaz) – Ali Zarei Mahmoudabadi 21–24 Lymphoabdominal paracoccidioidomycosis simulating primary neoplasia of the biliary tract – Fábio Luis Silva do Prado, Renata Prado, Cecı́lia Campos Valadares Gontijo, Ricardo Miguel Costa de Freitas, Maria Clara Nunes Pereira, Ivie Braga de Paula & Enio Roberto Pietra Pedroso 25–28
Gastrointestinal Radiology, 1990
... Carlo Fugazzola, 1 Carlo Procacci, 1 Ivo Andrea Bergamo Andreis, 1 Calogero Iacono, 2 Antonel... more ... Carlo Fugazzola, 1 Carlo Procacci, 1 Ivo Andrea Bergamo Andreis, 1 Calogero Iacono, 2 Antonella Portuese, ~ Giancarlo Mansueto, a Elena Residori ... In: Riz-zatto G, Solbiati L, Derchi L, Busilacehi P (eds): Imaging-US, A vanzamenti '88, Milano: Masson, 1989, pp 119-129 29. ...
Archives of Breast Cancer
Background: Autoimmune/inflammatory syndrome (ASIA) constitutes a set of related immune mediated ... more Background: Autoimmune/inflammatory syndrome (ASIA) constitutes a set of related immune mediated diseases that share a common clinical picture and a history of a previous exposure to an adjuvant agent. From a clinical standpoint, patients present with none specific manifestations such as myalgia, arthralgia, chronic fatigue and dry mouth as well as neurological manifestations such as cognitive disturbances, memory loss and neurologic disabilities. .Case presentation: A previously healthy 25-year-old patient who underwent breast augmentation 3 years ago, with an asymptomatic rupture of the silicone breast implant, presented with three major criteria of ASIA, and improved after bilateral implant removal. She also had pleuritis and pericarditis, rarely described in such disease. A literature review on complications related to breast implants, their questionable relationship to the onset of autoimmune pathologies, and basic aspects of the diagnosis and management of ASIA was carried out...
Radiologia Brasileira
OBJETIVO: Avaliar e discutir as indicações de ressonância magnética das mamas em um centro de ref... more OBJETIVO: Avaliar e discutir as indicações de ressonância magnética das mamas em um centro de referência oncológico. MATERIAIS E MÉTODOS: Estudo retrospectivo, aprovado pelo Comitê de Ética e Pesquisa da instituição, conduzido através da revisão de prontuários e laudos médicos. Foram incluídos todos os exames de ressonância magnética das mamas realizados no período de julho de 2008 a julho de 2009 (n = 529). RESULTADOS: A idade média das pacientes foi de 49 anos, variando de 17 a 86 anos. História familiar de câncer de mama e/ou ovário esteve presente em 162 pacientes (30,6%). As indicações mais comuns de ressonância magnética das mamas foram esclarecimento de achados inconclusivos na mamografia e/ou ultrassom (48,8%), avaliação de recorrência tumoral/cicatriz cirúrgica (15,1%), estadiamento/planejamento cirúrgico (11,7%) e rastreamento de pacientes de alto risco (8,5%). CONCLUSÃO: Apesar de achados inconclusivos nos exames convencionais serem a indicação mais comum de ressonância m...
Revista da Sociedade …, 2010
Introduction: The purpose of this study was to compare respiratory signs and symptoms between pat... more Introduction: The purpose of this study was to compare respiratory signs and symptoms between patients with and without chest X-ray abnormalities in order to establish the meaning of radiographic findings in pulmonary PCM diagnosis. Methods: The epidemiological, clinical and radiological lung findings of 44 patients with paracoccidiodomycosis (PCM) were evaluated. Patients were divided into two groups of 23 and 21 individuals according to the presence (group 1) or absence (group 2) of chest X-ray abnormalities, respectively, and their clinical data was analyzed with the aid of statistical tools. Results: As a general rule, patients were rural workers, young adult males and smokers-group 1 and 2, respectively: males (91.3% and 66.7%); mean age (44.4 and 27.9 year-old); smoking (34.7% and 71.4 %); acute/subacute presentation (38.1% and 21.7%); chronic presentation (61.9% and 78.3%). The most frequent respiratory manifestations were-group 1 and 2, respectively: cough (25% and 11.4%) and dyspnea (22.7% and 6.8%). No statistical difference was observed in pulmonary signs and symptoms between patients with or without radiographic abnormalities. The most frequent radiological finding was nodular (23.8%) or nodular-fibrous (19%), bilateral (90.5%) and diffuse infiltrates (85.7%). Conclusions: Absence of statistical difference in pulmonary signs and symptoms between these two groups of patients with PCM indicates clinical-radiological dissociation. A simplified classification of radiological lung PCM findings is suggested, based on correlation of these data and current literature review.