Jérémie Bon Betemps - Academia.edu (original) (raw)

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Papers by Jérémie Bon Betemps

Research paper thumbnail of doi:10.1016/S1359-6349(06)70486-4

Research paper thumbnail of Body Shaping and Volume Restoration: The Role of Hyaluronic Acid

Driven by the rising popularity of minimally invasive techniques, the demand for cosmetic procedu... more Driven by the rising popularity of minimally invasive techniques, the demand for cosmetic procedures is increasing. Cosmetic body-shaping procedures can be categorized into those that remove tissue and those that add volume. This review focuses on the latter of these categories, particularly on the use of resorbable hyaluronic acid gels specifically developed for minimally invasive volume enhancement. Pilot studies of hyaluronic acid involving its injection to contour various body deformities and its recent use in female breast augmentation are discussed. Injectable hyaluronic acid is effective and well tolerated. It represents an attractive treatment option for volume restoration or augmentation by providing predictable long-lasting results after minimally invasive administration. Alternative treatment options for volume enhancement also are summarized including fat transfer, silicone implants, and the use of injectable nonresorbable products such as silicone, polyalkylimide, and polyacrylamide gels. As patients continue to opt for nonsurgical procedures that offer predictable results, the development of minimally invasive products such as hyaluronic acid is increasingly important.

Research paper thumbnail of Pain Reduction in Local Anesthetic Administration Through pH Buffering

The effects of pH buffering on the pare of administration and efficacy of three local anesthetics... more The effects of pH buffering on the pare of administration and efficacy of three local anesthetics (1% lidocaine, 1% lidocaine with 1:100,000 epinephrine, and 1% mepivacaine) were investigated in a randomized, prospective, double-blind study of 25 adult volunteers. Plain and buffered solutions of the three local anesthetics were prepared, and a 0.5 intradermal injection of each was administered. Pain of anesthetic infiltration was rated from zero to ten. The area of anesthetized skin surrounding each injection site was measured at time intervals following each injection. Buffering the local anesthetics significantly reduced the mean quantitative pain estimates compared to the nonbuffered controls: I) 1% lidocaine compared with buffered 1% lidocaine, 4.9 +_ 0.4 versus 1.1 +_ 0.2 (P < 10 6); 2) 1% lidocaine with epinephrine compared with buffered 1% lidocaine with epinephrine, 5.1 +_ 0.4 versus 1.8 +-0.4 (P < 10 6); and 3) 1% mepivacaine compared with buffered 1% mepivacaine, 5.1 +_ 0.4 versus 0.9 +_ 0.2 (P < 10-6). Onset, extent, and duration of skin anesthesia were not statistically altered by pH buffering.

Research paper thumbnail of doi:10.1016/S1359-6349(06)70486-4

Research paper thumbnail of Body Shaping and Volume Restoration: The Role of Hyaluronic Acid

Driven by the rising popularity of minimally invasive techniques, the demand for cosmetic procedu... more Driven by the rising popularity of minimally invasive techniques, the demand for cosmetic procedures is increasing. Cosmetic body-shaping procedures can be categorized into those that remove tissue and those that add volume. This review focuses on the latter of these categories, particularly on the use of resorbable hyaluronic acid gels specifically developed for minimally invasive volume enhancement. Pilot studies of hyaluronic acid involving its injection to contour various body deformities and its recent use in female breast augmentation are discussed. Injectable hyaluronic acid is effective and well tolerated. It represents an attractive treatment option for volume restoration or augmentation by providing predictable long-lasting results after minimally invasive administration. Alternative treatment options for volume enhancement also are summarized including fat transfer, silicone implants, and the use of injectable nonresorbable products such as silicone, polyalkylimide, and polyacrylamide gels. As patients continue to opt for nonsurgical procedures that offer predictable results, the development of minimally invasive products such as hyaluronic acid is increasingly important.

Research paper thumbnail of Pain Reduction in Local Anesthetic Administration Through pH Buffering

The effects of pH buffering on the pare of administration and efficacy of three local anesthetics... more The effects of pH buffering on the pare of administration and efficacy of three local anesthetics (1% lidocaine, 1% lidocaine with 1:100,000 epinephrine, and 1% mepivacaine) were investigated in a randomized, prospective, double-blind study of 25 adult volunteers. Plain and buffered solutions of the three local anesthetics were prepared, and a 0.5 intradermal injection of each was administered. Pain of anesthetic infiltration was rated from zero to ten. The area of anesthetized skin surrounding each injection site was measured at time intervals following each injection. Buffering the local anesthetics significantly reduced the mean quantitative pain estimates compared to the nonbuffered controls: I) 1% lidocaine compared with buffered 1% lidocaine, 4.9 +_ 0.4 versus 1.1 +_ 0.2 (P < 10 6); 2) 1% lidocaine with epinephrine compared with buffered 1% lidocaine with epinephrine, 5.1 +_ 0.4 versus 1.8 +-0.4 (P < 10 6); and 3) 1% mepivacaine compared with buffered 1% mepivacaine, 5.1 +_ 0.4 versus 0.9 +_ 0.2 (P < 10-6). Onset, extent, and duration of skin anesthesia were not statistically altered by pH buffering.

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