Joško Bezić - Academia.edu (original) (raw)
Papers by Joško Bezić
Drugi kongres Hrvatskog senološkog društva : knjiga sažetaka, 2003
Acta Clinica Croatica, 2002
MELINK HK. The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration i... more MELINK HK. The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT) type. Cancer Res 1997;57:3944-8. 11. WOTHERSPOON AC, FINN TM, ISAACSON PG. Trisomy 3 in low-grade B-cell lymphomas of mucosa-associated lymphoid tissue.
Breast Disease, 2016
We herein report a case of the breast fibroadenoma with foci of so-called immature variant of the... more We herein report a case of the breast fibroadenoma with foci of so-called immature variant of the conventional ductal hyperplasia. This type of usual ductal hyperplasia is histologically characterised by encircling intraductal proliferation of large cells with pale to amphophilic cytoplasm and large nuclei which vary in shape and in staining quality of the chromatin. We showed here, using the cytokeratin immunohistochemistry, that the proliferating cells were not of immature but rather mature immunohistochemical phenotype. Because of the presented discordance between immature histology and mature immunohistological profile we suggest that this rare type of usual ductal hyperplasia should be called "immature-like".
Parasite (Paris, France), 2003
Human infections with filarial worms were for the first time diagnosed and described in Croatia.
Lijec̆nic̆ki vjesnik
As a result of the use of screening mammography and the introduction of programs for early detect... more As a result of the use of screening mammography and the introduction of programs for early detection of breast cancers, many breast biopsies are now performed for small, non-palpable, mammographically detected abnormalities. In contrast to breast biopsies in the premammographic era, breast biopsies for mammographic abnormalities contain a greater number of minimal invasive breast cancers (T1a,b), non-invasive-in situ cancers (Tis), and histological types of breast cancers with excellent prognosis. The aim of this study was to estimate the basic histopathologic features of breast cancers in Split region, with emphasis on in situ and minimal invasive cancers. The results of this study are achieved by analysis of pathohistologic characteristics of 937 breast cancers surgically removed in Split Clinical Hospital in the five year period (1997-2001), detected in population without early breast cancer detection programs. The proportion of minimal invasive cancers (T1a,b) and in situ cancer...
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2005
We report a case of cutaneous angiosarcoma in a 77-year-old female patient with systemic sclerosi... more We report a case of cutaneous angiosarcoma in a 77-year-old female patient with systemic sclerosis. The tumor developed around a large telangiectasia in the left temporal region. Later on, extensive asymptomatic redness and edema with several nodules over the whole left side of the face developed. Since the conservative therapy failed to produce any improvement, a diagnostic skin biopsy was performed. The pathohistological diagnosis was moderately differentiated angiosarcoma. The patient was treated with a combination of chemotherapy and electron beam irradiation. Despite a notable cutaneous improvement, the control check-up revealed the presence of metastases of the lung and liver. This is the first report of cutaneous angiosarcoma occurring in sclerodermatous skin. The possible pathogenesis of this rare tumorogenic transformation of soft tissues is discussed.
Seminari iz kliničke radiologije, 2005
Ovo poglavlje u knjizi bavi se radioloskom dijagnostikom bolesti gastrointestinalnog i hepatobili... more Ovo poglavlje u knjizi bavi se radioloskom dijagnostikom bolesti gastrointestinalnog i hepatobilijarnog sustava.
International Journal of Surgical Pathology
Proliferativne lezije specijalizirane strome prostate su rijetke, s tek izoliranim prikazima bole... more Proliferativne lezije specijalizirane strome prostate su rijetke, s tek izoliranim prikazima bolesnika u literaturi. Ove su promjene karakterizirane naznačenom proliferacijom strome prostate u kojoj se nalaze žlijezde obložene nepromijenjnim ili hiperplastičnim epitelom. U novije je vrijeme ova grupa tumora označena kao prostatična stromalna proliferacija nesigurnoga malignog potencijala. Ponašanje se ovakvih promjena ne može procijeniti na temelju njihovog histološkoga izgleda. U ovom smo radu prikazali muškarca u dobi od 71 godine kojemu je napravljena adenomektomija transvezikalnim pristupom zbog smetnji pri mokrenju. Na temelju histološke slike i munohistokemijske analize, postavljena je dijagnoza prostatične stromalne proliferacije nesigurnoga malignoga potencijala. Nakon petogodišnjeg razdoblja praćenja kod bolesnika nije došlo do razvoja recidiva niti transformacije u prostatični stromalni sarkom. U diferencijalnoj dijagnozi treba razmotiriti stromalni sarkom prostate, leiomi...
ABSTRACTAimTo examine ABO and Rh blood group distribution in COVID-19 related deaths considering ... more ABSTRACTAimTo examine ABO and Rh blood group distribution in COVID-19 related deaths considering demographics and pathological conditions.Materials and MethodsWe conducted a retrospective study at the University Hospital Centre Split, Croatia, that included 245 COVID-positive individuals that died from April 8, 2020, to January 25, 2021. From the hospital database, we extracted data on their blood groups, demographics, and pre-existing comorbidities. To compare findings with the general population, we used information from collected blood group donations (n = 101357) and statistical reports of non-COVID deaths from 2019 (n = 4968).ResultsThe proportion of males was significantly higher in analyzed subjects than in non- COVID deaths from 2019 (63.7% vs. 48.9%, P < 0.001), while the proportion of older individuals did not differ (P = 0.8). The most common pre-existing diseases were hypertension (59.6%), diabetes (37.1%), heart failure (28.8%), digestive disorder (26.5%), and solid ...
Onkologija je integralna disciplina u kojoj su sadržana mnoga znanja, disciplina koja zahtijeva r... more Onkologija je integralna disciplina u kojoj su sadržana mnoga znanja, disciplina koja zahtijeva razumijevanje, posvecenost, ljubav i zajednistvo. Osnove onkologije su preduvjet međusobnog razumijevanja i zajednistva, uspjesnosti onkoloskog lijecenja, a te osnove donosi ovaj udžbenik. Danas svjedocimo onkoloskoj revoluciji, promjeni neizljecivoga statusa raka do bolesti s relativno, ili u nekim sijelima apsolutno dobrim izgledima za izljecenje. Svjedocimo promjeni akutnoga u kronicno stanje raka. Danas bolesnici s metastatskim rakom imaju znacajno bolje sanse za dugotrajna preživljenja, a sve zahvaljujuci multidisciplinarnom pristupu u lijecenju i novim ciljanim terapijskim mogucnostima. Eticki zahtjevi koji se postavljaju pred lijecnika vrlo su specificni za ovo podrucje medicine, a najteže je donositi odluke u situacijama za koje ne postoje jasna pravila i utvrđena stajalista. Lijecnik mora istodobno zadržati otvorenost i kriticnost prema razlicitim pristupima i ne smije, bez jasni...
Pathologica, 2002
Collagenous spherulosis of the breast is distinctive breast histological finding characterised by... more Collagenous spherulosis of the breast is distinctive breast histological finding characterised by the accumulation of basement membrane material in form of eosinophilic or rarely basophilic spherules that exhibit concentric and radiating fibrillar patterns. It is usually an incidental microscopic uni- or multifocal finding that occurs adjacent to benign proliferative lesions, but it can be also coexistent with malignant breast processes. Its occurrence within a malignant process is exceptional. We present a case of collagenous spherulosis of the breast associated with poorly differentiated carcinoma in situ in a 54-year-old woman. This rare change can be misinterpreted as adenoid cystic carcinoma.
Drugi kongres Hrvatskog senološkog društva : knjiga sažetaka, 2003
Acta Clinica Croatica, 2002
MELINK HK. The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration i... more MELINK HK. The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT) type. Cancer Res 1997;57:3944-8. 11. WOTHERSPOON AC, FINN TM, ISAACSON PG. Trisomy 3 in low-grade B-cell lymphomas of mucosa-associated lymphoid tissue.
Breast Disease, 2016
We herein report a case of the breast fibroadenoma with foci of so-called immature variant of the... more We herein report a case of the breast fibroadenoma with foci of so-called immature variant of the conventional ductal hyperplasia. This type of usual ductal hyperplasia is histologically characterised by encircling intraductal proliferation of large cells with pale to amphophilic cytoplasm and large nuclei which vary in shape and in staining quality of the chromatin. We showed here, using the cytokeratin immunohistochemistry, that the proliferating cells were not of immature but rather mature immunohistochemical phenotype. Because of the presented discordance between immature histology and mature immunohistological profile we suggest that this rare type of usual ductal hyperplasia should be called "immature-like".
Parasite (Paris, France), 2003
Human infections with filarial worms were for the first time diagnosed and described in Croatia.
Lijec̆nic̆ki vjesnik
As a result of the use of screening mammography and the introduction of programs for early detect... more As a result of the use of screening mammography and the introduction of programs for early detection of breast cancers, many breast biopsies are now performed for small, non-palpable, mammographically detected abnormalities. In contrast to breast biopsies in the premammographic era, breast biopsies for mammographic abnormalities contain a greater number of minimal invasive breast cancers (T1a,b), non-invasive-in situ cancers (Tis), and histological types of breast cancers with excellent prognosis. The aim of this study was to estimate the basic histopathologic features of breast cancers in Split region, with emphasis on in situ and minimal invasive cancers. The results of this study are achieved by analysis of pathohistologic characteristics of 937 breast cancers surgically removed in Split Clinical Hospital in the five year period (1997-2001), detected in population without early breast cancer detection programs. The proportion of minimal invasive cancers (T1a,b) and in situ cancer...
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2005
We report a case of cutaneous angiosarcoma in a 77-year-old female patient with systemic sclerosi... more We report a case of cutaneous angiosarcoma in a 77-year-old female patient with systemic sclerosis. The tumor developed around a large telangiectasia in the left temporal region. Later on, extensive asymptomatic redness and edema with several nodules over the whole left side of the face developed. Since the conservative therapy failed to produce any improvement, a diagnostic skin biopsy was performed. The pathohistological diagnosis was moderately differentiated angiosarcoma. The patient was treated with a combination of chemotherapy and electron beam irradiation. Despite a notable cutaneous improvement, the control check-up revealed the presence of metastases of the lung and liver. This is the first report of cutaneous angiosarcoma occurring in sclerodermatous skin. The possible pathogenesis of this rare tumorogenic transformation of soft tissues is discussed.
Seminari iz kliničke radiologije, 2005
Ovo poglavlje u knjizi bavi se radioloskom dijagnostikom bolesti gastrointestinalnog i hepatobili... more Ovo poglavlje u knjizi bavi se radioloskom dijagnostikom bolesti gastrointestinalnog i hepatobilijarnog sustava.
International Journal of Surgical Pathology
Proliferativne lezije specijalizirane strome prostate su rijetke, s tek izoliranim prikazima bole... more Proliferativne lezije specijalizirane strome prostate su rijetke, s tek izoliranim prikazima bolesnika u literaturi. Ove su promjene karakterizirane naznačenom proliferacijom strome prostate u kojoj se nalaze žlijezde obložene nepromijenjnim ili hiperplastičnim epitelom. U novije je vrijeme ova grupa tumora označena kao prostatična stromalna proliferacija nesigurnoga malignog potencijala. Ponašanje se ovakvih promjena ne može procijeniti na temelju njihovog histološkoga izgleda. U ovom smo radu prikazali muškarca u dobi od 71 godine kojemu je napravljena adenomektomija transvezikalnim pristupom zbog smetnji pri mokrenju. Na temelju histološke slike i munohistokemijske analize, postavljena je dijagnoza prostatične stromalne proliferacije nesigurnoga malignoga potencijala. Nakon petogodišnjeg razdoblja praćenja kod bolesnika nije došlo do razvoja recidiva niti transformacije u prostatični stromalni sarkom. U diferencijalnoj dijagnozi treba razmotiriti stromalni sarkom prostate, leiomi...
ABSTRACTAimTo examine ABO and Rh blood group distribution in COVID-19 related deaths considering ... more ABSTRACTAimTo examine ABO and Rh blood group distribution in COVID-19 related deaths considering demographics and pathological conditions.Materials and MethodsWe conducted a retrospective study at the University Hospital Centre Split, Croatia, that included 245 COVID-positive individuals that died from April 8, 2020, to January 25, 2021. From the hospital database, we extracted data on their blood groups, demographics, and pre-existing comorbidities. To compare findings with the general population, we used information from collected blood group donations (n = 101357) and statistical reports of non-COVID deaths from 2019 (n = 4968).ResultsThe proportion of males was significantly higher in analyzed subjects than in non- COVID deaths from 2019 (63.7% vs. 48.9%, P < 0.001), while the proportion of older individuals did not differ (P = 0.8). The most common pre-existing diseases were hypertension (59.6%), diabetes (37.1%), heart failure (28.8%), digestive disorder (26.5%), and solid ...
Onkologija je integralna disciplina u kojoj su sadržana mnoga znanja, disciplina koja zahtijeva r... more Onkologija je integralna disciplina u kojoj su sadržana mnoga znanja, disciplina koja zahtijeva razumijevanje, posvecenost, ljubav i zajednistvo. Osnove onkologije su preduvjet međusobnog razumijevanja i zajednistva, uspjesnosti onkoloskog lijecenja, a te osnove donosi ovaj udžbenik. Danas svjedocimo onkoloskoj revoluciji, promjeni neizljecivoga statusa raka do bolesti s relativno, ili u nekim sijelima apsolutno dobrim izgledima za izljecenje. Svjedocimo promjeni akutnoga u kronicno stanje raka. Danas bolesnici s metastatskim rakom imaju znacajno bolje sanse za dugotrajna preživljenja, a sve zahvaljujuci multidisciplinarnom pristupu u lijecenju i novim ciljanim terapijskim mogucnostima. Eticki zahtjevi koji se postavljaju pred lijecnika vrlo su specificni za ovo podrucje medicine, a najteže je donositi odluke u situacijama za koje ne postoje jasna pravila i utvrđena stajalista. Lijecnik mora istodobno zadržati otvorenost i kriticnost prema razlicitim pristupima i ne smije, bez jasni...
Pathologica, 2002
Collagenous spherulosis of the breast is distinctive breast histological finding characterised by... more Collagenous spherulosis of the breast is distinctive breast histological finding characterised by the accumulation of basement membrane material in form of eosinophilic or rarely basophilic spherules that exhibit concentric and radiating fibrillar patterns. It is usually an incidental microscopic uni- or multifocal finding that occurs adjacent to benign proliferative lesions, but it can be also coexistent with malignant breast processes. Its occurrence within a malignant process is exceptional. We present a case of collagenous spherulosis of the breast associated with poorly differentiated carcinoma in situ in a 54-year-old woman. This rare change can be misinterpreted as adenoid cystic carcinoma.