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Jaroslav Flegr

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Papers by Jaroslav Flegr

Research paper thumbnail of Parasitism as the main factor shaping peptide vocabularies in current organisms

Parasitology, Feb 28, 2017

Research paper thumbnail of Stability-based sorting: The forgotten process behind (not only) biological evolution

Research paper thumbnail of General environmental heterogeneity as the explanation of sexuality? Comparative study shows that ancient asexual taxa are associated with both biotically and abiotically homogeneous environments

Research paper thumbnail of New approach and new permutation tests with R programs for analyses of false negatives-contaminated data in medicine and biology

Research paper thumbnail of A Rapid Method for Isolation of Double Stranded RNA

Preparative biochemistry, Dec 1, 1987

Research paper thumbnail of Effect of Partnership Status on Preferences for Facial Self-Resemblance

Frontiers in Psychology, Jun 14, 2016

Research paper thumbnail of Multiple populations of double-stranded RNA in two virus-harbouring strains ofTrichomonas vaginalis

Folia Microbiologica, Dec 1, 1988

The existence of six dsRNA segments of Trichomonas vaginalis virus was confirmed and the molar ma... more The existence of six dsRNA segments of Trichomonas vaginalis virus was confirmed and the molar mass and relative abundance of these segments were determined by agarose gel electrophoresis with reovirus dsRNA serving as a standard. The M's were 3.5, 3.4, 3.2, 2.5, 1.4 and 0.34 Mg/mol for the two strains studied, the relative abundances, however, were 1.0, 1.4, 3.0, 0.3, 2.7, 4.2 and 1.0, 0.6, 1.7, 0.5, 3.4 1.0 for these strains, respectively. Cell homogenate fractionation showed that all dsRNA segments were associated with viral particles. The data appeared to support the hypothesis of a relationship between viruses of the protozoan T. vaginalis and of the yeast Saccharomyces cerevisiae.

Research paper thumbnail of <p class="HeadingRunIn"><strong>Why <em>Drosophila</em> is not <em>Drosophila</em> any more, why it will be worse and what can be done about it?</strong></p>

Research paper thumbnail of The evolutionary history of testicular externalization and the origin of the scrotum

Journal of Biosciences, Feb 5, 2010

Research paper thumbnail of Toxoplasmosis – A Global Threat. Correlation of Latent Toxoplasmosis with Specific Disease Burden in a Set of 88 Countries

Research paper thumbnail of Exposing and exploiting host–parasite arms race clues in SARS-CoV-2: a principally new method for improved T cell immunogenicity prediction

Biology Methods and Protocols, 2023

Research paper thumbnail of Evolution by Non-individual Selection Pressures

Research paper thumbnail of Host Manipulation by Toxoplasma gondii

Research paper thumbnail of Toxoplasmosis: An important risk factor for acquiring SARS-CoV-2 infection and a severe course of Covid-19 disease, a cross-sectional study

Research Square (Research Square), May 28, 2021

Research paper thumbnail of Macroevolutionary Freezing and the Janusian Nature of Evolvability: Is the Evolution Going to End?

Research paper thumbnail of RRR - Rand - Novakova

Research paper thumbnail of Zamrzlá evoluce aneb je to jinak, pane Darwin

Research paper thumbnail of Effects of multiple gene control on the spread of altruism by group selection

arXiv (Cornell University), Feb 22, 2010

Research paper thumbnail of The effects of 105 biological, socioeconomic, behavioral, and environmental factors on the risk of SARS-CoV-2 infection and a severe course of COVID-19: a prospective, explorative cohort study

Biology Methods and Protocols, 2022

The confirmed number of SARS-CoV-2 infections up to 18 October 2022 is 626 million worldwide, bu... more The confirmed number of SARS-CoV-2 infections up to 18 October 2022 is 626 million worldwide, but information about factors affecting the probability of infection or a severe course of COVID-19 remains insufficient and often speculative. Only a small number of factors have been rigorously examined, mostly by retrospective or cross-sectional studies. We ran a preregistered study on 5164 Internet users who shared information with us about their exposure to 105 risk factors and reported being COVID-19 negative before the beginning of the fourth wave of COVID-19 in the Czech Republic. After the fourth wave, in which 709 (13.7%) of participants were infected, we used a partial Kendall test controlled for sex, age, and urbanization to compare the risk of infection and a severe course of the disease in subjects who initially did and did not report exposure to particular risk factors. After the correction for multiple tests, we identified 13 factors – including male sex, lower age, blood group B, and larger household size – that increased the risk of infection and 16 factors – including mask-wearing, borreliosis in the past, use of vitamin D supplements, or rooibos drinking – that decreased it. We also identified 23 factors that increased the risk of a severe course of COVID-19 and 12 factors that decreased the risk. This preregistered longitudinal study is of explorative nature. Therefore, although the observed effects were strong and remained highly significant even after correction for multiple tests, it will be necessary to confirm their existence in future independent studies.

Research paper thumbnail of Physical and Mental Health Status in Toxoplasma-Infected Women before and 3 Years after They Learn about Their Infection: Manipulation or Side-Effects of Impaired Health?

Frontiers in Ecology and Evolution, Nov 21, 2017

Research paper thumbnail of Parasitism as the main factor shaping peptide vocabularies in current organisms

Parasitology, Feb 28, 2017

Research paper thumbnail of Stability-based sorting: The forgotten process behind (not only) biological evolution

Research paper thumbnail of General environmental heterogeneity as the explanation of sexuality? Comparative study shows that ancient asexual taxa are associated with both biotically and abiotically homogeneous environments

Research paper thumbnail of New approach and new permutation tests with R programs for analyses of false negatives-contaminated data in medicine and biology

Research paper thumbnail of A Rapid Method for Isolation of Double Stranded RNA

Preparative biochemistry, Dec 1, 1987

Research paper thumbnail of Effect of Partnership Status on Preferences for Facial Self-Resemblance

Frontiers in Psychology, Jun 14, 2016

Research paper thumbnail of Multiple populations of double-stranded RNA in two virus-harbouring strains ofTrichomonas vaginalis

Folia Microbiologica, Dec 1, 1988

The existence of six dsRNA segments of Trichomonas vaginalis virus was confirmed and the molar ma... more The existence of six dsRNA segments of Trichomonas vaginalis virus was confirmed and the molar mass and relative abundance of these segments were determined by agarose gel electrophoresis with reovirus dsRNA serving as a standard. The M&amp;amp;#39;s were 3.5, 3.4, 3.2, 2.5, 1.4 and 0.34 Mg/mol for the two strains studied, the relative abundances, however, were 1.0, 1.4, 3.0, 0.3, 2.7, 4.2 and 1.0, 0.6, 1.7, 0.5, 3.4 1.0 for these strains, respectively. Cell homogenate fractionation showed that all dsRNA segments were associated with viral particles. The data appeared to support the hypothesis of a relationship between viruses of the protozoan T. vaginalis and of the yeast Saccharomyces cerevisiae.

Research paper thumbnail of <p class="HeadingRunIn"><strong>Why <em>Drosophila</em> is not <em>Drosophila</em> any more, why it will be worse and what can be done about it?</strong></p>

Research paper thumbnail of The evolutionary history of testicular externalization and the origin of the scrotum

Journal of Biosciences, Feb 5, 2010

Research paper thumbnail of Toxoplasmosis – A Global Threat. Correlation of Latent Toxoplasmosis with Specific Disease Burden in a Set of 88 Countries

Research paper thumbnail of Exposing and exploiting host–parasite arms race clues in SARS-CoV-2: a principally new method for improved T cell immunogenicity prediction

Biology Methods and Protocols, 2023

Research paper thumbnail of Evolution by Non-individual Selection Pressures

Research paper thumbnail of Host Manipulation by Toxoplasma gondii

Research paper thumbnail of Toxoplasmosis: An important risk factor for acquiring SARS-CoV-2 infection and a severe course of Covid-19 disease, a cross-sectional study

Research Square (Research Square), May 28, 2021

Research paper thumbnail of Macroevolutionary Freezing and the Janusian Nature of Evolvability: Is the Evolution Going to End?

Research paper thumbnail of RRR - Rand - Novakova

Research paper thumbnail of Zamrzlá evoluce aneb je to jinak, pane Darwin

Research paper thumbnail of Effects of multiple gene control on the spread of altruism by group selection

arXiv (Cornell University), Feb 22, 2010

Research paper thumbnail of The effects of 105 biological, socioeconomic, behavioral, and environmental factors on the risk of SARS-CoV-2 infection and a severe course of COVID-19: a prospective, explorative cohort study

Biology Methods and Protocols, 2022

The confirmed number of SARS-CoV-2 infections up to 18 October 2022 is 626 million worldwide, bu... more The confirmed number of SARS-CoV-2 infections up to 18 October 2022 is 626 million worldwide, but information about factors affecting the probability of infection or a severe course of COVID-19 remains insufficient and often speculative. Only a small number of factors have been rigorously examined, mostly by retrospective or cross-sectional studies. We ran a preregistered study on 5164 Internet users who shared information with us about their exposure to 105 risk factors and reported being COVID-19 negative before the beginning of the fourth wave of COVID-19 in the Czech Republic. After the fourth wave, in which 709 (13.7%) of participants were infected, we used a partial Kendall test controlled for sex, age, and urbanization to compare the risk of infection and a severe course of the disease in subjects who initially did and did not report exposure to particular risk factors. After the correction for multiple tests, we identified 13 factors – including male sex, lower age, blood group B, and larger household size – that increased the risk of infection and 16 factors – including mask-wearing, borreliosis in the past, use of vitamin D supplements, or rooibos drinking – that decreased it. We also identified 23 factors that increased the risk of a severe course of COVID-19 and 12 factors that decreased the risk. This preregistered longitudinal study is of explorative nature. Therefore, although the observed effects were strong and remained highly significant even after correction for multiple tests, it will be necessary to confirm their existence in future independent studies.

Research paper thumbnail of Physical and Mental Health Status in Toxoplasma-Infected Women before and 3 Years after They Learn about Their Infection: Manipulation or Side-Effects of Impaired Health?

Frontiers in Ecology and Evolution, Nov 21, 2017

Research paper thumbnail of Jaroslav Flegr: Frozen Evolution, or that is not the way it is, Mr. Darwin

Jaroslav Flegr: Frozen Evolution, or that is not the way it is, Mr. Darwin

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