Joseph Iberet - Academia.edu (original) (raw)
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Papers by Joseph Iberet
International journal of emerging trends in science and technology, 2014
Naphthoquinones are common compounds found in several species of Bignoniaceae and exhibit anti pl... more Naphthoquinones are common compounds found in several species of Bignoniaceae and exhibit anti plasmodial activity hence providing leads for discovery and development of anti theilerial drugs. This study has established the presence of naphthoquinones in the leaf, stem bark and root bark of S. kunthianum for both the hydrophilic and lipophilic extracts and established the anti theilerial activity of the lipophilic root bark extract. Sixteen unknown naphthoquinones in both the lipophilic and hydrophilic extracts of the leaf; stem bark and root bark of S. kunthianum were screened by Thin layer chromatographic technique. The lipophilic root bark extract of S.kunthianum caused death of macroschizonts of T.parva with 18 % mean percentage activity at a start experimental dose of 1 µg/L. The mean percentage activity against macroschizonts of T. parva increased with increase in the concentration of the lipophilic root bark extract of S. kunthianum . The in vitro Median Effective Concentrati...
Despite the limited availability of safety and efficacy information about a number of herbal medi... more Despite the limited availability of safety and efficacy information about a number of herbal medicinal preparations, dispensing and use of these products is one of the common health care practices in Uganda. Although it is widely perceived that "natural" products are safe, evidence suggests that herbal medicinal product use is not without risk. Without clear information on the labels of herbal medicinal products on the Ugandan market, some of the potentially toxic herbs known could be among the ingredients contained therein. This review highlights the use of herbal medicines as alternative or complimentary medicine, common herbal medicinal products on the Ugandan market, examples of potentially toxic herbs, adverse effects of common herbal medicinal products/ingredients on the Ugandan market, and recommendations on the use of herbal medicinal products in pregnancy. There is need to have more strict measures to control the use of these herbal medicinal products in Uganda otherwise the patients preferring herbal medicinal products are not safe. A toxicological study on the herbal medicinal products on the Ugandan market to ascertain their safety in preclinical as well as clinical settings is highly recommended.
International journal of emerging trends in science and technology, 2014
Naphthoquinones are common compounds found in several species of Bignoniaceae and exhibit anti pl... more Naphthoquinones are common compounds found in several species of Bignoniaceae and exhibit anti plasmodial activity hence providing leads for discovery and development of anti theilerial drugs. This study has established the presence of naphthoquinones in the leaf, stem bark and root bark of S. kunthianum for both the hydrophilic and lipophilic extracts and established the anti theilerial activity of the lipophilic root bark extract. Sixteen unknown naphthoquinones in both the lipophilic and hydrophilic extracts of the leaf; stem bark and root bark of S. kunthianum were screened by Thin layer chromatographic technique. The lipophilic root bark extract of S.kunthianum caused death of macroschizonts of T.parva with 18 % mean percentage activity at a start experimental dose of 1 µg/L. The mean percentage activity against macroschizonts of T. parva increased with increase in the concentration of the lipophilic root bark extract of S. kunthianum . The in vitro Median Effective Concentrati...
Despite the limited availability of safety and efficacy information about a number of herbal medi... more Despite the limited availability of safety and efficacy information about a number of herbal medicinal preparations, dispensing and use of these products is one of the common health care practices in Uganda. Although it is widely perceived that "natural" products are safe, evidence suggests that herbal medicinal product use is not without risk. Without clear information on the labels of herbal medicinal products on the Ugandan market, some of the potentially toxic herbs known could be among the ingredients contained therein. This review highlights the use of herbal medicines as alternative or complimentary medicine, common herbal medicinal products on the Ugandan market, examples of potentially toxic herbs, adverse effects of common herbal medicinal products/ingredients on the Ugandan market, and recommendations on the use of herbal medicinal products in pregnancy. There is need to have more strict measures to control the use of these herbal medicinal products in Uganda otherwise the patients preferring herbal medicinal products are not safe. A toxicological study on the herbal medicinal products on the Ugandan market to ascertain their safety in preclinical as well as clinical settings is highly recommended.