Jacqueline Mugnier - Academia.edu (original) (raw)
Papers by Jacqueline Mugnier
Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 358474. ...
The American Journal of Gastroenterology, Oct 1, 2018
Histopathology, Jul 5, 2018
Introduction: Lung transplant monitoring is usually assessed by forceps transbronchial biopsies. ... more Introduction: Lung transplant monitoring is usually assessed by forceps transbronchial biopsies. These types of biopsies show limited reliability and high degree of variability due to insufficient material and compression artefact, which lead to misinterpretation and eventually mistreatment of the transplanted patients. The following study was undertaken to assess the diagnostic yield, histological quality and safety of cryobiopsy in comparison with conventional forceps biopsy for sampling lung tissue in transplant recipients. Materials and Methods: From January to December 2011, 81 consecutive transbronchial biopsies (41 forceps and 40 cryoprobe) were indicated in single or bilateral lung transplantation recipients with clinical acute or chronic lung injury.
Case reports in hepatology, Dec 9, 2018
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant ... more Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver disease. The clinical presentation is unspecific, with symptoms ranging from abdominal pain, malaise, and weight loss to atypical manifestation which include hyperammonemic encephalopathy. We present the case of a 33-year-old woman with no prior medical history who presented with a coma and a diagnosis of inoperable fibrolamellar hepatocarcinoma requiring a cadaver donor transplant. While she was on the waiting list, she received hemofiltration and ammonium benzoate treatment, with progressive improvement in her state of consciousness.
Revista colombiana de neumologia, Apr 4, 2014
La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosu... more La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosupresión que presentan compromiso del sistema nervioso central. Sin embargo, este germen tiene la capacidad de infectar también hospederos inmunocompetentes. En este artículo se describe el caso de una paciente sin antecedentes patológicos que desarrolló criptococosis pulmonar, y se realiza una breve revisión de la epidemiología, presentación clínica, hallazgos radiológicos, diagnóstico y tratamiento de esta patología que es infrecuente o quizás, subdiagnosticada.
Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica, 2019
INTRODUCTION Calcifying fibrous pseudotumor is a rare benign lesion with few peritoneal and mesen... more INTRODUCTION Calcifying fibrous pseudotumor is a rare benign lesion with few peritoneal and mesenteric cases in pediatric population described. Its course is mainly asymptomatic, which is why diagnosis corresponds mostly to incidental findings. CLINICAL CASE Authors present the case of a 9-year-old patient with abdominal pain, and intra-abdominal mass finding in abdominal tomography. The histopathological study realized established diagnosis of calcifying fibrous pseudotumor, which is why programmed resection of the mass was performed by laparotomy. Follow-up was performed during one year, without evidence of recurrences through ecography. COMMENTS Authors discuss the diagnostic and therapeutic approach in this patient compared to that described in the literature.
ASAIO Journal, 2009
Use of occluder devices for a patent ductus arteriosus (PDA) closure is restricted to small diame... more Use of occluder devices for a patent ductus arteriosus (PDA) closure is restricted to small diameter PDAs and involves high device costs. The objective of this study was to develop a new nitinol implant for the closure of a PDA and to evaluate its safety and efficacy in an animal model. The design consists of a device that promotes thrombus formation in the PDA. The device has a double-cone shape with their vertices joined. The cones are made of a nitinol wire helix with dacron fibers attached. The proximal end of the helix can be screwed to a conventional catheter release wire. In vitro testing was performed to verify the effectiveness of the implantation of the device and its releasing system; all trials (n ؍ 30) were successful, showing accurate placement and release of the device. Complete and successful implantation of the device was achieved in all in vivo experiments (n ؍ 5). There was one case of embolization due to premature detachment; a second device was successfully implanted. Histological evaluation after 42.3 ؎ 3.1 days demonstrated complete PDA occlusion. The retrieved PDA showed total closure of the defect, endothelization of the PDA outlets and proper lodging of the device.
Acta neurol. …, 2003
Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 358474. ...
Revista Colombiana de Neumología, May 10, 2018
Artículo de revisión radiológica Resumen La sarcoidosis es una enfermedad crónica y multisistémic... more Artículo de revisión radiológica Resumen La sarcoidosis es una enfermedad crónica y multisistémica de causa poco conocida, con un pico de incidencia entre los 20 y 29 años, con mayor prevalencia en el género femenino y en la raza negra. El órgano más frecuentemente afectado es el pulmón (90%), que es sintomático solamente en el 50%. El diagnóstico requiere confirmación histopatológica, excepto en pacientes con la triada de Löfgren. El hallazgo histológico característico es la presencia de granulomas no caseificantes, con células gigantes multinucleadas. Las manifestaciones radiológicas de la enfermedad pulmonar por sarcoidosis son amplias e incluyen manifestaciones típicas de compromiso ganglionar (adenomegalias hiliares bilaterales y paratraqueales derechas) y parenquimatoso (nódulos perilinfáticos, opacidades parahiliares bilaterales y cambios por fibrosis) y manifestaciones atípicas de compromiso ganglionar (adenomegalias unilaterales, asimétricas), parenquimatoso (sarcoidosis alveolar y masas pulmonares), enfermedad de vía aérea, pleural y otras (micetomas). El 30% de los pacientes tiene compromiso extrapulmonar, más frecuentemente hepático (40%-60%). El pronóstico de esta entidad es bueno, con una remisión en el 66% de los pacientes, y se basa en la clasificación de Scadding para la radiografía de tórax, aunque estudios en escanografía han demostrado que hallazgos como los nódulos centrilobulillares, la consolidación, el vidrio esmerilado y el engrosamiento de septos interlobulillares se correlacionan con reversibilidad de las alteraciones en imágenes.
Revista Colombiana de Neumología, 2014
La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosu... more La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosupresión que presentan compromiso del sistema nervioso central. Sin embargo, este germen tiene la capacidad de infectar también hospederos inmunocompetentes. En este artículo se describe el caso de una paciente sin antecedentes patológicos que desarrolló criptococosis pulmonar, y se realiza una breve revisión de la epidemiología, presentación clínica, hallazgos radiológicos, diagnóstico y tratamiento de esta patología que es infrecuente o quizás, subdiagnosticada.
Acta Médica Colombiana, 2019
Femenina de 65 años con leucemia linfoide crónica que presentó lesiones tipo vesículas, pústulas ... more Femenina de 65 años con leucemia linfoide crónica que presentó lesiones tipo vesículas, pústulas y costras con extensión a dorso, cara, tórax y abdomen (Figura 1 y 2), considerando pustulosis exantemática aguda generalizada vs varicela zoster iniciando manejo con aciclovir y estudio con PCR para varicela zoster, por demora de PCR y el riesgo de exposición a aciclovir se solicito Test de Tzank confirmando infección por herpes virus (Figura 3), atribuido a varicela zoster completando esquema de aciclovir, finalmente se recibe reporte de PCR positivo para este. El Test de Tzank un test rápido, simple y no costoso para examinar las lesiones vesiculares y confirmar infección por herpes virus con la limitación de no diferenciar infección por herpes simplex virus 1,2 o 3, es en un test con buen rendimiento operativo (sensibilidad de 40-80% y especificidad hasta del 100%) ante la duda diagnostica de infección por herpes virus.
Histopathology, Jan 19, 2018
Lung transplant monitoring is usually performed with forceps transbronchial biopsies. These types... more Lung transplant monitoring is usually performed with forceps transbronchial biopsies. These types of biopsy show limited reliability and a high degree of variability, owing to insufficient material and compression artefact, which lead to misinterpretation and, eventually, inappropriate treatment of the transplanted patients. The following study was undertaken to assess the diagnostic yield, histological quality and safety of cryobiopsy (CB) in comparison with conventional forceps biopsy (FB) for sampling lung tissue in transplant recipients. From January to December 2011, 81 consecutive transbronchial biopsies (41 FBs and 40 CBs) were indicated in single or bilateral lung transplantation recipients with clinical acute or chronic lung injury. Lung samples obtained by CB were larger (8.5 ± 6.5 mm in the FB group versus 22.1 ± 12.5 mm in the CB group; P < 0.0001) and had no crush artefacts (P = 0.002), allowing us to increase the diagnostic yield of acute (P = 0.0657) and chronic (P...
Amc Acta Medica Colombiana, Jun 1, 1990
Se presenta la historia clinica, los estudios imagenologicos y los hallazgos quirurgicos de un ho... more Se presenta la historia clinica, los estudios imagenologicos y los hallazgos quirurgicos de un hombre de 28 anos con confirmacion inmunohistologica de hiperplasia focal de celulas beta del pancreas (nesidioblastosis)
Acta Colombiana de Cuidado Intensivo, 2015
Resumen Presentamos el caso de un hombre de 58 anos con sindrome febril prolongado asociado a dif... more Resumen Presentamos el caso de un hombre de 58 anos con sindrome febril prolongado asociado a dificultad respiratoria, episodios de broncoespasmo, deterioro de la funcion renal y mononeuropatia multiple que evoluciona a disfuncion organica multiple. Despues de un amplio estudio microbiologico, imagenologico, broncoscopico y citologico se diagnostico vasculitis ANCA positivo compatible con sindrome de Churg-Strauss. Tras el inicio de terapia inmunosupresora y ciclo de plasmaferesis el paciente evoluciona satisfactoriamente, se retira el soporte ventilatorio, inicia rehabilitacion y finalmente egresa.
Revista de la Facultad de Medicina, 2019
Introduction: Adrenocortical carcinoma (ACC) is a malignancy with an annual incidence of 0.72 cas... more Introduction: Adrenocortical carcinoma (ACC) is a malignancy with an annual incidence of 0.72 cases per million people. It is a rare tumor that is associated with high mortality in late stages, as well as with a 5-year survival of 13% in stage IV patients, and 61% in stage II lesions. Nevertheless, tumor recurrence occurs in up to 54% at 23 months with predominance of locoregional involvement, being striking the late presentation of tumor recurrence with extensive involvement.Case presentation: This is the case of a 52-year-old male patient with a history of resection of an ACC of 6cm five years earlier, who was admitted for decompensated heart failure. A chest x-ray was taken suggesting metastasis. After conducting biochemical studies and CT scan of the abdomen, ACC with metastases to liver and lung was diagnosed. The patient decided not to receive palliative chemotherapy.Conclusion: This unfortunate outcome is related to the lack of follow-up after the initial procedure. Clinical,...
Revista Colombiana de Neumología, 2020
Discusión multidisciplinaria en el diagnóstico de fibrosis pulmonar idiopática.
1Gastroenterology Fellowship, Universidad del Rosario, School of Medicine and Health Sciences, Bo... more 1Gastroenterology Fellowship, Universidad del Rosario, School of Medicine and Health Sciences, Bogotá, Colombia 2Department of Medicine, Division of Internal Medicine, Universidad del Rosario, Bogotá D.C., Cundinamarca, Colombia 3Department of Medicine, Division of Gastroenterology and Hepatology, Fundación Cardio Infantil, Bogotá D.C., Cundinamarca, Colombia 4Department of Medicine, Division of Pathology, Fundación Cardio Infantil, Bogotá D.C., Cundinamarca, Colombia
American Journal of Gastroenterology, 2018
Case Reports in Hepatology, 2018
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant ... more Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver disease. The clinical presentation is unspecific, with symptoms ranging from abdominal pain, malaise, and weight loss to atypical manifestation which include hyperammonemic encephalopathy. We present the case of a 33-year-old woman with no prior medical history who presented with a coma and a diagnosis of inoperable fibrolamellar hepatocarcinoma requiring a cadaver donor transplant. While she was on the waiting list, she received hemofiltration and ammonium benzoate treatment, with progressive improvement in her state of consciousness.
Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 358474. ...
The American Journal of Gastroenterology, Oct 1, 2018
Histopathology, Jul 5, 2018
Introduction: Lung transplant monitoring is usually assessed by forceps transbronchial biopsies. ... more Introduction: Lung transplant monitoring is usually assessed by forceps transbronchial biopsies. These types of biopsies show limited reliability and high degree of variability due to insufficient material and compression artefact, which lead to misinterpretation and eventually mistreatment of the transplanted patients. The following study was undertaken to assess the diagnostic yield, histological quality and safety of cryobiopsy in comparison with conventional forceps biopsy for sampling lung tissue in transplant recipients. Materials and Methods: From January to December 2011, 81 consecutive transbronchial biopsies (41 forceps and 40 cryoprobe) were indicated in single or bilateral lung transplantation recipients with clinical acute or chronic lung injury.
Case reports in hepatology, Dec 9, 2018
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant ... more Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver disease. The clinical presentation is unspecific, with symptoms ranging from abdominal pain, malaise, and weight loss to atypical manifestation which include hyperammonemic encephalopathy. We present the case of a 33-year-old woman with no prior medical history who presented with a coma and a diagnosis of inoperable fibrolamellar hepatocarcinoma requiring a cadaver donor transplant. While she was on the waiting list, she received hemofiltration and ammonium benzoate treatment, with progressive improvement in her state of consciousness.
Revista colombiana de neumologia, Apr 4, 2014
La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosu... more La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosupresión que presentan compromiso del sistema nervioso central. Sin embargo, este germen tiene la capacidad de infectar también hospederos inmunocompetentes. En este artículo se describe el caso de una paciente sin antecedentes patológicos que desarrolló criptococosis pulmonar, y se realiza una breve revisión de la epidemiología, presentación clínica, hallazgos radiológicos, diagnóstico y tratamiento de esta patología que es infrecuente o quizás, subdiagnosticada.
Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica, 2019
INTRODUCTION Calcifying fibrous pseudotumor is a rare benign lesion with few peritoneal and mesen... more INTRODUCTION Calcifying fibrous pseudotumor is a rare benign lesion with few peritoneal and mesenteric cases in pediatric population described. Its course is mainly asymptomatic, which is why diagnosis corresponds mostly to incidental findings. CLINICAL CASE Authors present the case of a 9-year-old patient with abdominal pain, and intra-abdominal mass finding in abdominal tomography. The histopathological study realized established diagnosis of calcifying fibrous pseudotumor, which is why programmed resection of the mass was performed by laparotomy. Follow-up was performed during one year, without evidence of recurrences through ecography. COMMENTS Authors discuss the diagnostic and therapeutic approach in this patient compared to that described in the literature.
ASAIO Journal, 2009
Use of occluder devices for a patent ductus arteriosus (PDA) closure is restricted to small diame... more Use of occluder devices for a patent ductus arteriosus (PDA) closure is restricted to small diameter PDAs and involves high device costs. The objective of this study was to develop a new nitinol implant for the closure of a PDA and to evaluate its safety and efficacy in an animal model. The design consists of a device that promotes thrombus formation in the PDA. The device has a double-cone shape with their vertices joined. The cones are made of a nitinol wire helix with dacron fibers attached. The proximal end of the helix can be screwed to a conventional catheter release wire. In vitro testing was performed to verify the effectiveness of the implantation of the device and its releasing system; all trials (n ؍ 30) were successful, showing accurate placement and release of the device. Complete and successful implantation of the device was achieved in all in vivo experiments (n ؍ 5). There was one case of embolization due to premature detachment; a second device was successfully implanted. Histological evaluation after 42.3 ؎ 3.1 days demonstrated complete PDA occlusion. The retrieved PDA showed total closure of the defect, endothelization of the PDA outlets and proper lodging of the device.
Acta neurol. …, 2003
Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 358474 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 358474. ...
Revista Colombiana de Neumología, May 10, 2018
Artículo de revisión radiológica Resumen La sarcoidosis es una enfermedad crónica y multisistémic... more Artículo de revisión radiológica Resumen La sarcoidosis es una enfermedad crónica y multisistémica de causa poco conocida, con un pico de incidencia entre los 20 y 29 años, con mayor prevalencia en el género femenino y en la raza negra. El órgano más frecuentemente afectado es el pulmón (90%), que es sintomático solamente en el 50%. El diagnóstico requiere confirmación histopatológica, excepto en pacientes con la triada de Löfgren. El hallazgo histológico característico es la presencia de granulomas no caseificantes, con células gigantes multinucleadas. Las manifestaciones radiológicas de la enfermedad pulmonar por sarcoidosis son amplias e incluyen manifestaciones típicas de compromiso ganglionar (adenomegalias hiliares bilaterales y paratraqueales derechas) y parenquimatoso (nódulos perilinfáticos, opacidades parahiliares bilaterales y cambios por fibrosis) y manifestaciones atípicas de compromiso ganglionar (adenomegalias unilaterales, asimétricas), parenquimatoso (sarcoidosis alveolar y masas pulmonares), enfermedad de vía aérea, pleural y otras (micetomas). El 30% de los pacientes tiene compromiso extrapulmonar, más frecuentemente hepático (40%-60%). El pronóstico de esta entidad es bueno, con una remisión en el 66% de los pacientes, y se basa en la clasificación de Scadding para la radiografía de tórax, aunque estudios en escanografía han demostrado que hallazgos como los nódulos centrilobulillares, la consolidación, el vidrio esmerilado y el engrosamiento de septos interlobulillares se correlacionan con reversibilidad de las alteraciones en imágenes.
Revista Colombiana de Neumología, 2014
La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosu... more La infección por criptococo generalmente se diagnostica en individuos con algún grado de inmunosupresión que presentan compromiso del sistema nervioso central. Sin embargo, este germen tiene la capacidad de infectar también hospederos inmunocompetentes. En este artículo se describe el caso de una paciente sin antecedentes patológicos que desarrolló criptococosis pulmonar, y se realiza una breve revisión de la epidemiología, presentación clínica, hallazgos radiológicos, diagnóstico y tratamiento de esta patología que es infrecuente o quizás, subdiagnosticada.
Acta Médica Colombiana, 2019
Femenina de 65 años con leucemia linfoide crónica que presentó lesiones tipo vesículas, pústulas ... more Femenina de 65 años con leucemia linfoide crónica que presentó lesiones tipo vesículas, pústulas y costras con extensión a dorso, cara, tórax y abdomen (Figura 1 y 2), considerando pustulosis exantemática aguda generalizada vs varicela zoster iniciando manejo con aciclovir y estudio con PCR para varicela zoster, por demora de PCR y el riesgo de exposición a aciclovir se solicito Test de Tzank confirmando infección por herpes virus (Figura 3), atribuido a varicela zoster completando esquema de aciclovir, finalmente se recibe reporte de PCR positivo para este. El Test de Tzank un test rápido, simple y no costoso para examinar las lesiones vesiculares y confirmar infección por herpes virus con la limitación de no diferenciar infección por herpes simplex virus 1,2 o 3, es en un test con buen rendimiento operativo (sensibilidad de 40-80% y especificidad hasta del 100%) ante la duda diagnostica de infección por herpes virus.
Histopathology, Jan 19, 2018
Lung transplant monitoring is usually performed with forceps transbronchial biopsies. These types... more Lung transplant monitoring is usually performed with forceps transbronchial biopsies. These types of biopsy show limited reliability and a high degree of variability, owing to insufficient material and compression artefact, which lead to misinterpretation and, eventually, inappropriate treatment of the transplanted patients. The following study was undertaken to assess the diagnostic yield, histological quality and safety of cryobiopsy (CB) in comparison with conventional forceps biopsy (FB) for sampling lung tissue in transplant recipients. From January to December 2011, 81 consecutive transbronchial biopsies (41 FBs and 40 CBs) were indicated in single or bilateral lung transplantation recipients with clinical acute or chronic lung injury. Lung samples obtained by CB were larger (8.5 ± 6.5 mm in the FB group versus 22.1 ± 12.5 mm in the CB group; P < 0.0001) and had no crush artefacts (P = 0.002), allowing us to increase the diagnostic yield of acute (P = 0.0657) and chronic (P...
Amc Acta Medica Colombiana, Jun 1, 1990
Se presenta la historia clinica, los estudios imagenologicos y los hallazgos quirurgicos de un ho... more Se presenta la historia clinica, los estudios imagenologicos y los hallazgos quirurgicos de un hombre de 28 anos con confirmacion inmunohistologica de hiperplasia focal de celulas beta del pancreas (nesidioblastosis)
Acta Colombiana de Cuidado Intensivo, 2015
Resumen Presentamos el caso de un hombre de 58 anos con sindrome febril prolongado asociado a dif... more Resumen Presentamos el caso de un hombre de 58 anos con sindrome febril prolongado asociado a dificultad respiratoria, episodios de broncoespasmo, deterioro de la funcion renal y mononeuropatia multiple que evoluciona a disfuncion organica multiple. Despues de un amplio estudio microbiologico, imagenologico, broncoscopico y citologico se diagnostico vasculitis ANCA positivo compatible con sindrome de Churg-Strauss. Tras el inicio de terapia inmunosupresora y ciclo de plasmaferesis el paciente evoluciona satisfactoriamente, se retira el soporte ventilatorio, inicia rehabilitacion y finalmente egresa.
Revista de la Facultad de Medicina, 2019
Introduction: Adrenocortical carcinoma (ACC) is a malignancy with an annual incidence of 0.72 cas... more Introduction: Adrenocortical carcinoma (ACC) is a malignancy with an annual incidence of 0.72 cases per million people. It is a rare tumor that is associated with high mortality in late stages, as well as with a 5-year survival of 13% in stage IV patients, and 61% in stage II lesions. Nevertheless, tumor recurrence occurs in up to 54% at 23 months with predominance of locoregional involvement, being striking the late presentation of tumor recurrence with extensive involvement.Case presentation: This is the case of a 52-year-old male patient with a history of resection of an ACC of 6cm five years earlier, who was admitted for decompensated heart failure. A chest x-ray was taken suggesting metastasis. After conducting biochemical studies and CT scan of the abdomen, ACC with metastases to liver and lung was diagnosed. The patient decided not to receive palliative chemotherapy.Conclusion: This unfortunate outcome is related to the lack of follow-up after the initial procedure. Clinical,...
Revista Colombiana de Neumología, 2020
Discusión multidisciplinaria en el diagnóstico de fibrosis pulmonar idiopática.
1Gastroenterology Fellowship, Universidad del Rosario, School of Medicine and Health Sciences, Bo... more 1Gastroenterology Fellowship, Universidad del Rosario, School of Medicine and Health Sciences, Bogotá, Colombia 2Department of Medicine, Division of Internal Medicine, Universidad del Rosario, Bogotá D.C., Cundinamarca, Colombia 3Department of Medicine, Division of Gastroenterology and Hepatology, Fundación Cardio Infantil, Bogotá D.C., Cundinamarca, Colombia 4Department of Medicine, Division of Pathology, Fundación Cardio Infantil, Bogotá D.C., Cundinamarca, Colombia
American Journal of Gastroenterology, 2018
Case Reports in Hepatology, 2018
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant ... more Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver disease. The clinical presentation is unspecific, with symptoms ranging from abdominal pain, malaise, and weight loss to atypical manifestation which include hyperammonemic encephalopathy. We present the case of a 33-year-old woman with no prior medical history who presented with a coma and a diagnosis of inoperable fibrolamellar hepatocarcinoma requiring a cadaver donor transplant. While she was on the waiting list, she received hemofiltration and ammonium benzoate treatment, with progressive improvement in her state of consciousness.