James B. Lewis - Academia.edu (original) (raw)

Papers by James B. Lewis

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of Primary Gluteal Abscess Due to Salmonella typhimurium: A Case Report and Review of the Literature

American Journal of The Medical Sciences, 2007

Infections due to nontyphoidal salmonellae are common, and their incidence has been increasing in... more Infections due to nontyphoidal salmonellae are common, and their incidence has been increasing in the last few years. In this case report, we document the unusual finding of a gluteal abscess caused by Salmonella typhimurium in the absence of detectable bacteremia. Fluoroquinolones remain an important treatment option for salmonellosis, and to avoid potential treatment failures, we underscore the importance of routine screening for nalidixic acid susceptibility with all extraintestinal Salmonella isolates. To our knowledge, this is the first published case of S typhimurium gluteal abscess in the absence of bacteremia and risk factors for salmonellosis.

Research paper thumbnail of Abnormal expression of a late gene family L1 protein in monkey cells abortively infected with adenovirus type 2

Virus Genes, 1988

The drastically reduced virus yields obtained from monkey cells abortively infected with adenovir... more The drastically reduced virus yields obtained from monkey cells abortively infected with adenovirus 2 (Ad2) have been attributed primarily to a severe decrease in the accumulation of the virion protein fiber (IV), a product of the most pomoter distal late gene family, L5. Here we report that the accumulation of virion protein IIIa, a product of the proximal late gene family, L1, is also severely depressed. In contrast, the i-leader protein LO-13.6K and L1 protein(s) 52K/55K are expressed with the same time course and in equal amounts in monkey cells abortively infected by Ad2 or productively infected by the Ad2-simian virus 40 (SV40) hybrid Ad2+ND1 or by the host range mutant Ad2+ND3 hr602. L1-52K/55K is phosphorylated in abortively infected CV-1 or CV-C monkey cells as well as in productively infected human and monkey cells. As with fiber expression, the failure to produce IIIa appears to be due partly to reduced or delayed IIIa mRNA accumulation. The small amount of IIIa protein that is synthesized in monkey cells is stable. Since the accumulation of both IIIa and fiber protein is deficient, the mechanism of abortive infection cannot be attributed solely to the absence of the auxiliary fiber leader sequences (1).

Research paper thumbnail of Conditional Lethal Mutants ofAdenovirus Type2Simian Virus 40Hybrids II.Ad2+ND1Host-Range Mutants ThatSynthesize Fragments ofthe Ad2+ND130KProtein

Adenovirus type 2 (Ad2) grows 1,000 times less well in monkey cells than in human cells. This def... more Adenovirus type 2 (Ad2) grows 1,000 times less well in monkey cells than in human cells. This defect can be overcome, not only upon co-infection of cells with simian virus 40 (SV40), but also when the relevant part of the SV40 genome is integrated into the adenovirus genome to form an adenovirus-SV40 hybrid virus. We have used the nondefective Ad2-SV40

Research paper thumbnail of Analysis of Internet-Based Health Assessments

Health Promotion Practice, 2002

... attributes or factors in an individual's life (eg, self-esteem, purpose in life, lif... more ... attributes or factors in an individual's life (eg, self-esteem, purpose in life, life satisfaction). ... and that managing avid health-seeking patients within the confines of 15-minute appointments will be ... Simple “yes,” “no,” “not applicable/don't know” re-sponses were used in the survey. ...

Research paper thumbnail of Understanding School-Age Obesity: THROUGH PARTICIPATORY ACTION RESEARCH

Mcn-the American Journal of Maternal-child Nursing, 2008

This study aimed to assess current levels of overweight (obesity) and fitness among school studen... more This study aimed to assess current levels of overweight (obesity) and fitness among school students using objective data. School-based action research teams were recruited statewide by the New Hampshire Healthy Schools Coalition, the state team of the National Action for Healthy Kids Coalition. Action teams consisted of a physical education teacher, a school nurse, and a school administrator. Data were collected from 6,511 student participants aged 6 to 14 years, which was a representative cross-section from New Hampshire school districts. Key variables of interest in the study were body mass index, and ability to pass five fitness tests using FITNESSGRAM. Pearson's correlation was used to assess the relationships among body mass index, age, gender, and the percent of students that passed FITNESSGRAM tests. The ability of participants to pass the FITNESSGRAM tests declined markedly with age and differed between boys and girls, although the healthy fitness zones for any particular test was lower for girls. Body mass index was significantly negatively correlated with performance on all tests. Age was also statistically negatively correlated with performance on all tests; the relationship between gender and performance on the tests was less striking. Results reflected an increase in the prevalence of overweight school children, even in New Hampshire, which is purported to be one of the healthiest states in the nation. Results offered evidence that body mass index is a valid proxy measure for fitness levels and that fitness programs are necessary to effectively combat the obesity epidemic. Evidence-based changes need to be implemented to address obesity-related factors in schools, because children spend many of their waking hours in that setting. Physical activity during recess and physical education classes could help to increase energy expenditure and develop sound minds and bodies. Schools should consider the development of school-based wellness teams to advise and advocate improved school-based wellness policies. School nurses can take an active part in these initiatives.

Research paper thumbnail of DIAGNOSIS AND MANAGEMENT OF HEADACHE

Obstetrics and Gynecology Clinics of North America, 2001

Migraine and tension headaches are among the most common diagnoses in women's health. Sec... more Migraine and tension headaches are among the most common diagnoses in women's health. Secondary causes of headache such as brain tumor, subarachnoid hemorrhage, and meningitis are uncommon but must not be missed. A careful history and physical examination, use of diagnostic criteria, and certain facts about the serious causes of headache are the keys to diagnosis and treatment. Neuroimaging should be limited to patients displaying signs or symptoms of a secondary headache cause. Menstrual migraine can be managed similarly to nonmenstrual migraine.

Research paper thumbnail of Amino-terminal sequence of adenovirus type 2 proteins: hexon, fiber, component IX, and early protein 1B15K

Virology, 1980

The partial amino-terminal amino acid sequence was determined for four adenovirus 2 proteins: hex... more The partial amino-terminal amino acid sequence was determined for four adenovirus 2 proteins: hexon, fiber, component IX, and early protein E1B-15K. A comparison of these sequences with the nucleotide sequences of the region of the genome encoding each of these proteins has identified the initiation sites for protein synthesis. Each protein is initiated at the AUG codon nearest the 5'

Research paper thumbnail of Citrobacter freundii Empyema in a Patient with Occult Pulmonary Histoplasmosis

American Journal of The Medical Sciences, 1998

The genus Citrobacter includes three species of organisms that are uncommonly associated with hum... more The genus Citrobacter includes three species of organisms that are uncommonly associated with human infection. When they are pathogenic, there are usually one or more associated respiratory, urinary, skin-soft tissue, and central nervous system infections and neonatal sepsis. These infections occur in the wake of significant systemic illness or complicate antibiotic usage. Rarely, infection has been associated with active tuberculosis. The authors report a case of Citrobacter freundii empyema in a patient with occult pulmonary histoplasmosis.

Research paper thumbnail of Derivation of the Secondary Structure of 5S RNA from its Binding of Complementary Oligonucleotides

Research paper thumbnail of Impending Paradoxical Embolism

The advent of echocardiography has led to the more frequent discovery of impending paradoxical em... more The advent of echocardiography has led to the more frequent discovery of impending paradoxical embolism. Paradoxical embolism should be considered whenever there is an arterial embolism from an unidentified source in the presence of a concomitant venous thromboembolic phenomenon. Patients with paradoxical embolism present with neurological abnormalities or features suggesting arterial embolism. Annually, paradoxical embolism may account for up to 47,000 strokes in the United States, and a patent foramen ovale has been reported in up to 35% of the normal population. Events that give rise to pulmonary hypertension may result in a right-to-left shunt through a patent foramen ovale allowing a venous thromboembolism access to the arterial circulation. Herein we report a case of impending paradoxical embolism and review the pertinent literature.

Research paper thumbnail of Viral messenger RNAs in six lines of adenovirus-transformed cells

Research paper thumbnail of Academic achievement and primary care specialty selection of volunteers at a student-run free clinic

Teaching and learning in medicine, 2014

Previous studies have reached conflicting conclusions about the associations between service and ... more Previous studies have reached conflicting conclusions about the associations between service and academic achievement and service and primary care specialty choice. This study examines the associations between service at a student-run clinic and academic achievement and primary care specialty choice. Retrospective review of medical student service and statistical analysis of grade point average (GPA), Step 1 and Step 2 Clinical Knowledge (CK) scores, and specialty choice were conducted, as approved by our Institutional Review Board. Volunteers, compared to nonvolunteers, had higher GPA (3.59 ± 0.33 vs. 3.40 ± 0.39, p < .001), Step 1 (229 ± 19 vs. 220 ± 21, p < .001), and Step 2 CK (240 ± 18 vs. 230 ± 21, p < .001) scores, but did not pursue primary care specialties at a significantly higher percentage (52% vs. 51%, χ² = .051, p = .82). Further exploration of the associations between service and academic achievement and primary care specialty choice is warranted.

Research paper thumbnail of Stability or Decline? Demand or Supply?

Journal of Economic History - J ECON HIST, 2009

Research paper thumbnail of Using a General Internal Medicine Consult Service to Teach Residents and Care for Patients

American Journal of The Medical Sciences - AMER J MED SCI, 2003

... each resident and attending physician is referred to an up-to-date, online, 20-article syllab... more ... each resident and attending physician is referred to an up-to-date, online, 20-article syllabus and given ... UpToDate online requires a subscription and password for use ... undergo an operative procedure or who have been referred by a non-internal medicine service for evaluation. ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of A Concise History of Korea: From the Neolithic Period through the Nineteenth Century, and: Everlasting Flower: A History of Korea (review)

Journal of Korean Studies, 2008

Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment ... more Page 1. 84 kOREAN STUDIES, VOL. 3i Economic and institutional histories are given less treatment than one might ex-pect in a survey history. He also devotes less space to topics of interest to so-cial historians such as the ...

Research paper thumbnail of Primary Gluteal Abscess Due to Salmonella typhimurium: A Case Report and Review of the Literature

American Journal of The Medical Sciences, 2007

Infections due to nontyphoidal salmonellae are common, and their incidence has been increasing in... more Infections due to nontyphoidal salmonellae are common, and their incidence has been increasing in the last few years. In this case report, we document the unusual finding of a gluteal abscess caused by Salmonella typhimurium in the absence of detectable bacteremia. Fluoroquinolones remain an important treatment option for salmonellosis, and to avoid potential treatment failures, we underscore the importance of routine screening for nalidixic acid susceptibility with all extraintestinal Salmonella isolates. To our knowledge, this is the first published case of S typhimurium gluteal abscess in the absence of bacteremia and risk factors for salmonellosis.

Research paper thumbnail of Abnormal expression of a late gene family L1 protein in monkey cells abortively infected with adenovirus type 2

Virus Genes, 1988

The drastically reduced virus yields obtained from monkey cells abortively infected with adenovir... more The drastically reduced virus yields obtained from monkey cells abortively infected with adenovirus 2 (Ad2) have been attributed primarily to a severe decrease in the accumulation of the virion protein fiber (IV), a product of the most pomoter distal late gene family, L5. Here we report that the accumulation of virion protein IIIa, a product of the proximal late gene family, L1, is also severely depressed. In contrast, the i-leader protein LO-13.6K and L1 protein(s) 52K/55K are expressed with the same time course and in equal amounts in monkey cells abortively infected by Ad2 or productively infected by the Ad2-simian virus 40 (SV40) hybrid Ad2+ND1 or by the host range mutant Ad2+ND3 hr602. L1-52K/55K is phosphorylated in abortively infected CV-1 or CV-C monkey cells as well as in productively infected human and monkey cells. As with fiber expression, the failure to produce IIIa appears to be due partly to reduced or delayed IIIa mRNA accumulation. The small amount of IIIa protein that is synthesized in monkey cells is stable. Since the accumulation of both IIIa and fiber protein is deficient, the mechanism of abortive infection cannot be attributed solely to the absence of the auxiliary fiber leader sequences (1).

Research paper thumbnail of Conditional Lethal Mutants ofAdenovirus Type2Simian Virus 40Hybrids II.Ad2+ND1Host-Range Mutants ThatSynthesize Fragments ofthe Ad2+ND130KProtein

Adenovirus type 2 (Ad2) grows 1,000 times less well in monkey cells than in human cells. This def... more Adenovirus type 2 (Ad2) grows 1,000 times less well in monkey cells than in human cells. This defect can be overcome, not only upon co-infection of cells with simian virus 40 (SV40), but also when the relevant part of the SV40 genome is integrated into the adenovirus genome to form an adenovirus-SV40 hybrid virus. We have used the nondefective Ad2-SV40

Research paper thumbnail of Analysis of Internet-Based Health Assessments

Health Promotion Practice, 2002

... attributes or factors in an individual's life (eg, self-esteem, purpose in life, lif... more ... attributes or factors in an individual's life (eg, self-esteem, purpose in life, life satisfaction). ... and that managing avid health-seeking patients within the confines of 15-minute appointments will be ... Simple “yes,” “no,” “not applicable/don't know” re-sponses were used in the survey. ...

Research paper thumbnail of Understanding School-Age Obesity: THROUGH PARTICIPATORY ACTION RESEARCH

Mcn-the American Journal of Maternal-child Nursing, 2008

This study aimed to assess current levels of overweight (obesity) and fitness among school studen... more This study aimed to assess current levels of overweight (obesity) and fitness among school students using objective data. School-based action research teams were recruited statewide by the New Hampshire Healthy Schools Coalition, the state team of the National Action for Healthy Kids Coalition. Action teams consisted of a physical education teacher, a school nurse, and a school administrator. Data were collected from 6,511 student participants aged 6 to 14 years, which was a representative cross-section from New Hampshire school districts. Key variables of interest in the study were body mass index, and ability to pass five fitness tests using FITNESSGRAM. Pearson's correlation was used to assess the relationships among body mass index, age, gender, and the percent of students that passed FITNESSGRAM tests. The ability of participants to pass the FITNESSGRAM tests declined markedly with age and differed between boys and girls, although the healthy fitness zones for any particular test was lower for girls. Body mass index was significantly negatively correlated with performance on all tests. Age was also statistically negatively correlated with performance on all tests; the relationship between gender and performance on the tests was less striking. Results reflected an increase in the prevalence of overweight school children, even in New Hampshire, which is purported to be one of the healthiest states in the nation. Results offered evidence that body mass index is a valid proxy measure for fitness levels and that fitness programs are necessary to effectively combat the obesity epidemic. Evidence-based changes need to be implemented to address obesity-related factors in schools, because children spend many of their waking hours in that setting. Physical activity during recess and physical education classes could help to increase energy expenditure and develop sound minds and bodies. Schools should consider the development of school-based wellness teams to advise and advocate improved school-based wellness policies. School nurses can take an active part in these initiatives.

Research paper thumbnail of DIAGNOSIS AND MANAGEMENT OF HEADACHE

Obstetrics and Gynecology Clinics of North America, 2001

Migraine and tension headaches are among the most common diagnoses in women's health. Sec... more Migraine and tension headaches are among the most common diagnoses in women's health. Secondary causes of headache such as brain tumor, subarachnoid hemorrhage, and meningitis are uncommon but must not be missed. A careful history and physical examination, use of diagnostic criteria, and certain facts about the serious causes of headache are the keys to diagnosis and treatment. Neuroimaging should be limited to patients displaying signs or symptoms of a secondary headache cause. Menstrual migraine can be managed similarly to nonmenstrual migraine.

Research paper thumbnail of Amino-terminal sequence of adenovirus type 2 proteins: hexon, fiber, component IX, and early protein 1B15K

Virology, 1980

The partial amino-terminal amino acid sequence was determined for four adenovirus 2 proteins: hex... more The partial amino-terminal amino acid sequence was determined for four adenovirus 2 proteins: hexon, fiber, component IX, and early protein E1B-15K. A comparison of these sequences with the nucleotide sequences of the region of the genome encoding each of these proteins has identified the initiation sites for protein synthesis. Each protein is initiated at the AUG codon nearest the 5'

Research paper thumbnail of Citrobacter freundii Empyema in a Patient with Occult Pulmonary Histoplasmosis

American Journal of The Medical Sciences, 1998

The genus Citrobacter includes three species of organisms that are uncommonly associated with hum... more The genus Citrobacter includes three species of organisms that are uncommonly associated with human infection. When they are pathogenic, there are usually one or more associated respiratory, urinary, skin-soft tissue, and central nervous system infections and neonatal sepsis. These infections occur in the wake of significant systemic illness or complicate antibiotic usage. Rarely, infection has been associated with active tuberculosis. The authors report a case of Citrobacter freundii empyema in a patient with occult pulmonary histoplasmosis.

Research paper thumbnail of Derivation of the Secondary Structure of 5S RNA from its Binding of Complementary Oligonucleotides

Research paper thumbnail of Impending Paradoxical Embolism

The advent of echocardiography has led to the more frequent discovery of impending paradoxical em... more The advent of echocardiography has led to the more frequent discovery of impending paradoxical embolism. Paradoxical embolism should be considered whenever there is an arterial embolism from an unidentified source in the presence of a concomitant venous thromboembolic phenomenon. Patients with paradoxical embolism present with neurological abnormalities or features suggesting arterial embolism. Annually, paradoxical embolism may account for up to 47,000 strokes in the United States, and a patent foramen ovale has been reported in up to 35% of the normal population. Events that give rise to pulmonary hypertension may result in a right-to-left shunt through a patent foramen ovale allowing a venous thromboembolism access to the arterial circulation. Herein we report a case of impending paradoxical embolism and review the pertinent literature.

Research paper thumbnail of Viral messenger RNAs in six lines of adenovirus-transformed cells

Research paper thumbnail of Academic achievement and primary care specialty selection of volunteers at a student-run free clinic

Teaching and learning in medicine, 2014

Previous studies have reached conflicting conclusions about the associations between service and ... more Previous studies have reached conflicting conclusions about the associations between service and academic achievement and service and primary care specialty choice. This study examines the associations between service at a student-run clinic and academic achievement and primary care specialty choice. Retrospective review of medical student service and statistical analysis of grade point average (GPA), Step 1 and Step 2 Clinical Knowledge (CK) scores, and specialty choice were conducted, as approved by our Institutional Review Board. Volunteers, compared to nonvolunteers, had higher GPA (3.59 ± 0.33 vs. 3.40 ± 0.39, p < .001), Step 1 (229 ± 19 vs. 220 ± 21, p < .001), and Step 2 CK (240 ± 18 vs. 230 ± 21, p < .001) scores, but did not pursue primary care specialties at a significantly higher percentage (52% vs. 51%, χ² = .051, p = .82). Further exploration of the associations between service and academic achievement and primary care specialty choice is warranted.

Research paper thumbnail of Stability or Decline? Demand or Supply?

Journal of Economic History - J ECON HIST, 2009

Research paper thumbnail of Using a General Internal Medicine Consult Service to Teach Residents and Care for Patients

American Journal of The Medical Sciences - AMER J MED SCI, 2003

... each resident and attending physician is referred to an up-to-date, online, 20-article syllab... more ... each resident and attending physician is referred to an up-to-date, online, 20-article syllabus and given ... UpToDate online requires a subscription and password for use ... undergo an operative procedure or who have been referred by a non-internal medicine service for evaluation. ...