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Papers by James Carton
AME Medical Journal, 2021
liver, mesentery, testis, spermatic cord, para-aortic tissue, perirenal tissue (3), small and lar... more liver, mesentery, testis, spermatic cord, para-aortic tissue, perirenal tissue (3), small and large bowel (4), paraspinal soft tissues, anterior mediastinum, uterine cornu, upper arm and infundibular pelvic ligament (5). Because anastomosing haemangioma mimics primary renal angiosarcoma-a known diagnostic pitfall with implications on management and outcome-there is a need to better understand this
Current Urology Reports, 2018
Purpose of review Primary angiosarcoma of the kidney is extremely rare; hence relatively little i... more Purpose of review Primary angiosarcoma of the kidney is extremely rare; hence relatively little is known regarding its clinicopathologic features and prognosis. Herein, we review the literature on primary renal angiosarcoma with emphasis on the clinical and pathologic features. Recent findings Approximately 64 cases have been reported in the literature and most cases occur in the 6 th-7 th decade with a strong male predominance. The aetiology is unknown. Patients present with flank pain, haematuria, abdominal mass and weight loss. A considerable number of patients develop metastatic disease at diagnosis or shortly afterwards. Grossly, the tumour comprises ill-defined haemorrhagic spongy masses often with necrosis. Microscopically, the tumour is composed of anastomosing capillary-sized vessels which are lined by malignant endothelial cells. The mainstay of treatment is surgery followed by radiation therapy with or without chemotherapy. Summary Renal angiosarcomas are highly aggressive tumours with dismal outcome; and they must be distinguished from morphologically similar lesions of the kidney.
AME Medical Journal, 2021
liver, mesentery, testis, spermatic cord, para-aortic tissue, perirenal tissue (3), small and lar... more liver, mesentery, testis, spermatic cord, para-aortic tissue, perirenal tissue (3), small and large bowel (4), paraspinal soft tissues, anterior mediastinum, uterine cornu, upper arm and infundibular pelvic ligament (5). Because anastomosing haemangioma mimics primary renal angiosarcoma-a known diagnostic pitfall with implications on management and outcome-there is a need to better understand this
Current Urology Reports, 2018
Purpose of review Primary angiosarcoma of the kidney is extremely rare; hence relatively little i... more Purpose of review Primary angiosarcoma of the kidney is extremely rare; hence relatively little is known regarding its clinicopathologic features and prognosis. Herein, we review the literature on primary renal angiosarcoma with emphasis on the clinical and pathologic features. Recent findings Approximately 64 cases have been reported in the literature and most cases occur in the 6 th-7 th decade with a strong male predominance. The aetiology is unknown. Patients present with flank pain, haematuria, abdominal mass and weight loss. A considerable number of patients develop metastatic disease at diagnosis or shortly afterwards. Grossly, the tumour comprises ill-defined haemorrhagic spongy masses often with necrosis. Microscopically, the tumour is composed of anastomosing capillary-sized vessels which are lined by malignant endothelial cells. The mainstay of treatment is surgery followed by radiation therapy with or without chemotherapy. Summary Renal angiosarcomas are highly aggressive tumours with dismal outcome; and they must be distinguished from morphologically similar lesions of the kidney.