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Papers by James Dickerson

World Journal of Clinical Oncology

Mesoscale crumpled graphene oxide roses (GO roses) were synthesized by using colloidal graphene o... more Mesoscale crumpled graphene oxide roses (GO roses) were synthesized by using colloidal graphene oxide (GO) variants as precursors for a hybrid emulsification/rapid evaporation approach. This process produced rose-like, spherical, reduced mesostructures of colloidal graphene oxide, with corrugated surfaces and particle sizes ranging from ~800 nm to 15 μm. The morphology and chemical structure of these produced GO roses was investigated using electron microscopy and spectroscopy techniques. The proposed synthesis route provides control over particle size, morphology and chemical properties of the synthesized GO roses.

Journal of Clinical Oncology

e23160 Background: Immune checkpoint inhibitors (ICIs) have been met with a wave of excitement du... more e23160 Background: Immune checkpoint inhibitors (ICIs) have been met with a wave of excitement due to their novel mechanism. We hypothesized that this may impact how patients (via PROs) report treatment tolerability in comparison to traditional therapies. We sought to examine if there was a notable difference in PROs in blinded vs unblinded trials of ICIs. Methods: We systematically searched PubMed, CINAHL, Embase, Web of Science, and Scopus in August 2018 for publications with quantitative PRO data comparing ICIs to cytotoxic chemotherapy. Case series, narrative reviews, and publications lacking original data were excluded. Eligible publications were reviewed to assess if patients were blinded to the agent received, and a comparison for common PRO metrics was performed. Results: Of the 1,450 unique references identified, eight met inclusion criteria: 1 double blinded placebo-controlled trial and 7 trials where patients were aware of the assigned arm. The blinded trial had quantitat...

The Journal of Physical Chemistry C

Child's Nervous System, 2017

Arterial cerebral aneurysms in the neonatal population are rare, and while the association of int... more Arterial cerebral aneurysms in the neonatal population are rare, and while the association of interrupted aortic arch and intracranial aneurysm has been reported in the adult and pediatric population (three cases each), to date, it has not been reported in the neonate. We report the case of a 26-day-old girl who presented with a generalized seizure 2 weeks after undergoing congenital heart surgery. Head CT revealed diffuse SAH with a 1.7 × 2.9-cm frontal intra-parenchymal hematoma with subdural extension producing 3 mm of midline shift. CTA evidenced a 2-mm left MCA bifurcation aneurysm, and the patient was taken to the operating room for clipping. Twenty-four-hour post-operative head CT showed ventriculomegaly and an EVD was placed. It was removed 4 days later without the need for permanent CSF diversion, and after this, her hospital stay was uneventful and she was discharged home. At 25 months of age, she was meeting developmental milestones. At this time, she underwent further heart surgery and expired shortly thereafter due to cardiomyopathy. Here, we report the successful treatment of a ruptured neonatal aneurysm, and the first known case associated with interrupted aortic arch. Given the time and presentation, this patient likely illustrates the role of hemodynamic factors in the rupture of neonatal aneurysms. In reviewing all of the reported cases of neonatal aneurysms, promptly securing the aneurysm by either open clipping, parent vessel occlusion, or endovascular coiling is strongly preferable to no surgical intervention.

Sensors and Actuators B: Chemical, 2013

ABSTRACT The electrophoretic deposition (EPD) of nanoparticles (NPs) of the catalytic metal plati... more ABSTRACT The electrophoretic deposition (EPD) of nanoparticles (NPs) of the catalytic metal platinum (Pt) onto semiconductor wafers of indium phosphide (InP) from colloid solution in isooctane was studied at room temperature. The colloid solution for EPD was prepared by the chemical reduction of water solutions of the metal salts, confined to AOT reverse micelles in isooctane with hydrazine reducing agent. Four EPD-cast samples of Pt NPs were prepared on polished n-type InP wafers with varying times of deposition. The sheet density of Pt NPs varied from approximately 10% coverage of the substrate to 100% coverage of the substrate by several monolayers of Pt NPs, as observed by SEM. EPD was performed on a masked surface, enabling to make separated small deposited spots. Schottky contacts were made on the deposited spots by printing the contacts with colloidal graphite. The time response of the current to a 0.1% hydrogen exposure exhibited a continuous increase of saturation current and a decrease of the response time with increasing Pt NPs sheet density. Layers of Pt NPs were also prepared on p-type InP wafers. The current of the p-type InP diodes was observed to decrease with the exposure to hydrogen; its decrease was much smaller than the increase of current in n-type InP diodes. This demonstrates that two mechanisms are involved in formation of the hydrogen dipole layer. We have suggested the increase in hydrogen affinity by correlation effects as the second mechanism added to the well known hydrogen polarization by the electric field of the Schottky barrier.

ACS applied materials & interfaces, Jan 3, 2016

We report on the formation of Pt nanoparticle monolayers by electrophoretic deposition from nonpo... more We report on the formation of Pt nanoparticle monolayers by electrophoretic deposition from nonpolar solvents. First, the growth kinetics of Pt nanoparticles prepared by the reverse micelle technique are described in detail. Second, a model of nanoparticle charging in nonpolar media is discussed and methods to control the nanoparticle charging are proposed. Finally, essential parameters of the electrophoretic deposition process to control the deposition of nanoparticle monolayers are discussed and mechanisms of their formation are analyzed.

Advanced Energy Materials, 2016

Journal of Vinyl and Additive Technology, 1989

Page 1. A Comparison of Oven Sag Temperature and Heat Deflection Temperature for Measuring Heat R... more Page 1. A Comparison of Oven Sag Temperature and Heat Deflection Temperature for Measuring Heat Resistance MICHAEL M. BALASKO, JAMES W. SUMMERS, JAMES L. DICKERSON, and ERNEST0 L. RODRIGUEZ Geon ...

Macromolecules have long been known to affect the flow behavior of fluids in turbulent flow. Line... more Macromolecules have long been known to affect the flow behavior of fluids in turbulent flow. Linear, high molecular weight, polymer solutions show a much lower coefficient of friction in turbulent flow than does the solvent alone, even at extremely low concentrations. This phenomenon has been termed "drag reduction.". Well characterized, high molecular weight, water -soluble polymers have been used to examine fluid behavior in both tube flow and disk flow. Polymer physical and chemical properties which enhance drag reduction as well as practical methods of utilizing these polymer solutions have also been examined. A mathematical model which treats drag reduction as physical interactions has also been developed. This model is compared to drag reduction results from several simple water-soluble polymer samples. The model gives explanations for inconsistencies that arise in DR measurement using different flow geometries. The model is mathematically equivalent to the empirical relationships of Virk et al. and McCormick et al. The model shows that increasing the molecular weight (or degree of polymerization) increases the polymer hydrodynamic coil size which increases the chance of collision between a polymer coil and a turbulent flow region. Increasing molecular weight also increases the effectiveness of this collision to reduce turbulence which may be related to the extensional viscosity of the polymer solution.

Nano Energy, 2012

ABSTRACT Research on nanostructured fuel cell electrodes has recently been growing significantly.... more ABSTRACT Research on nanostructured fuel cell electrodes has recently been growing significantly. Although improvements on the charge capacity and lifetime of nanostructured electrodes have been frequently reported, an analytical evaluation of the energy loss of nanostructured fuel cells is still lacking. In this communication, an electrochemical cell is designed and analyzed to measure the gas diffusivities through electrodes. With the measured gas diffusivities, the correlation between the concentration polarization energy loss and the important parameters associated with nanoscale electrodes in gas–fuel based fuel cells, such as temperature, and the porosity of the electrodes, can be efficiently analyzed.