Jane Haslam - Academia.edu (original) (raw)

Papers by Jane Haslam

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La presente invention concerne un procede et un systeme de caracterisation d'une articulation... more La presente invention concerne un procede et un systeme de caracterisation d'une articulation en termes de morphologie squelettique. Une pluralite de sites associes au modele d'une structure squelettique d'articulation du genou sont fixes et utilises pour parametrer des positions de cette pluralite de sites chez un sujet donne et, pour calculer ainsi des parametres d'un modele statistique deformable. La morphologie squelettique est ensuite caracterisee a partir des parametres calcules de ce modele statistique deformable.

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L'invention concerne un procede et un systeme de detection et de suivi de l'osteoporose. ... more L'invention concerne un procede et un systeme de detection et de suivi de l'osteoporose. Le procede selon l'invention permet de caracteriser une image d'une vertebre cible en construisant un modele informatique a partir d'un ensemble d'echantillons d'images de variations pathologiques et non pathologiques des vertebres representant des variations dans la forme des vertebres. Ledit procede consiste egalement a recevoir une image d'une vertebre cible d'un sujet, et a automatiquement estimer le contour des limites laterales des plaques corticales inferieures sur l'image. On varie les parametres du modele afin de determiner un ensemble representant une forme modele qui se rapproche du contour estime des limites des plaques corticales. Le procede consiste a automatiquement caracteriser la vertebre cible sur la base de l'ensemble de parametres de modele qui ont ete determines, et a sortir sur un dispositif d'affichage la caracterisation de l...

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The Spine Journal, 2015

Despite its clinical importance, accurate identification of vertebral fractures is problematic an... more Despite its clinical importance, accurate identification of vertebral fractures is problematic and time-consuming. There is a recognized need to improve the detection of vertebral fractures so that appropriate high-risk patients can be selected to initiate clinically beneficial therapeutic interventions. To develop and evaluate semiautomatic algorithms for detailed annotation of vertebral bodies from T4 to L4 in digitized lateral spinal dual-energy X-ray absorptiometry (DXA) vertebral fracture assessment (VFA) images. Using lateral spinal DXA VFA images from subjects imaged at University Hospital fracture liaison service, image algorithms were developed for semiautomatic detailed annotation of vertebral bodies from T4 to L4. Two hundred one women aged 50 years or older with nonvertebral fractures. Algorithm accuracy and precision. Statistical models of vertebral shape and appearance from T4 to L4 were constructed using VFA images from 130 subjects. The resulting models form a part of an algorithm for performing semiautomatic detailed annotation of vertebral bodies from T4 to L4. Algorithm accuracy and precision were evaluated on a test-set of 71 independent images. Overall accuracy was 0.72 mm (3.00% of vertebral height) and overall precision was 0.26 mm (1.11%) for point-to-line distance. Accuracy and precision were best on normal vertebrae (0.65 mm [2.67%] and 0.21 mm [0.90%], respectively) and mild fractures (0.78 mm [3.18%] and 0.32 mm [1.39%], respectively), but accuracy and precision errors were higher for moderate (1.07 mm [4.66%] and 0.48 mm [2.15%], respectively) and severe fractures (2.07 mm [9.65%] and 1.10 mm [5.09%], respectively). Accuracy and precision results for the algorithm were comparable with other reported results in the literature. This semiautomatic image analysis had high overall accuracy and precision on normal vertebrae and mild fractures, but performed less well in moderate and severe fractures. It is, therefore, a useful tool to identify normality of vertebral shape and to identify mild fractures.

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Procedings of the British Machine Vision Conference 1994, 1994

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Quantification of Brain Function Using PET, 1996

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Bone, 2014

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Spine, 2013

Study design randomized intra- and inter-reader reproducibility study. To evaluate reproducibilit... more Study design randomized intra- and inter-reader reproducibility study. To evaluate reproducibility of quantitative morphometry (QM) and agreement of dichotomous fracture/no-fracture status on lateral spinal radiographs acquired during routine clinical practice using a clinical workflow tool. Several recent guidelines have underlined the importance of Genant semi-quantitative scoring and selective QM to confirm and grade suspected vertebral fractures in clinical practice. Thoracic and lumbar spine radiographs were acquired from 98 consecutive subjects (mean age, 60.1 ± 11.7 yr) attending the clinic for osteoporosis evaluation. For each subject, QM and Genant semi-quantitative scoring were performed on all evaluable vertebrae from L4 to T4 using a software workflow tool. A radiologist and an experienced radiographical technician performed 2 repeat reading sessions of the radiographs 12 months apart, blinded to each other's results; for the second read, the cases were anonymized and the order was randomized. Inter-reader reproducibility results were 3.1% and 3.2% coefficient of variation (%) for heights, 0.030 and 0.031 root mean square standard deviation for height ratios. For intrareader reproducibility, these values were 2.2% and 3.5% coefficient of variation %; 0.023 and 0.034 root mean square standard deviation. Kappa score results for agreement of dichotomous fracture/no-fracture status were 0.67 and 0.72 (inter-rater) and 0.50 and 0.67 (intrarater). The software assessed in this study is a reliable clinical tool that facilitates QM and Genant semi-quantitative scoring of the spine in routine clinical practice. 3.

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Nuclear Medicine Communications, 1995

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Image and Vision Computing, 1994

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Bone, 2010

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Bone, 2014

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La presente invention concerne un procede et un systeme de caracterisation d'une articulation... more La presente invention concerne un procede et un systeme de caracterisation d'une articulation en termes de morphologie squelettique. Une pluralite de sites associes au modele d'une structure squelettique d'articulation du genou sont fixes et utilises pour parametrer des positions de cette pluralite de sites chez un sujet donne et, pour calculer ainsi des parametres d'un modele statistique deformable. La morphologie squelettique est ensuite caracterisee a partir des parametres calcules de ce modele statistique deformable.

Bookmarks Related papers MentionsView impact

Bookmarks Related papers MentionsView impact

L'invention concerne un procede et un systeme de detection et de suivi de l'osteoporose. ... more L'invention concerne un procede et un systeme de detection et de suivi de l'osteoporose. Le procede selon l'invention permet de caracteriser une image d'une vertebre cible en construisant un modele informatique a partir d'un ensemble d'echantillons d'images de variations pathologiques et non pathologiques des vertebres representant des variations dans la forme des vertebres. Ledit procede consiste egalement a recevoir une image d'une vertebre cible d'un sujet, et a automatiquement estimer le contour des limites laterales des plaques corticales inferieures sur l'image. On varie les parametres du modele afin de determiner un ensemble representant une forme modele qui se rapproche du contour estime des limites des plaques corticales. Le procede consiste a automatiquement caracteriser la vertebre cible sur la base de l'ensemble de parametres de modele qui ont ete determines, et a sortir sur un dispositif d'affichage la caracterisation de l...

Bookmarks Related papers MentionsView impact

Bookmarks Related papers MentionsView impact

Bookmarks Related papers MentionsView impact

Bookmarks Related papers MentionsView impact

Bookmarks Related papers MentionsView impact

Bookmarks Related papers MentionsView impact

The Spine Journal, 2015

Despite its clinical importance, accurate identification of vertebral fractures is problematic an... more Despite its clinical importance, accurate identification of vertebral fractures is problematic and time-consuming. There is a recognized need to improve the detection of vertebral fractures so that appropriate high-risk patients can be selected to initiate clinically beneficial therapeutic interventions. To develop and evaluate semiautomatic algorithms for detailed annotation of vertebral bodies from T4 to L4 in digitized lateral spinal dual-energy X-ray absorptiometry (DXA) vertebral fracture assessment (VFA) images. Using lateral spinal DXA VFA images from subjects imaged at University Hospital fracture liaison service, image algorithms were developed for semiautomatic detailed annotation of vertebral bodies from T4 to L4. Two hundred one women aged 50 years or older with nonvertebral fractures. Algorithm accuracy and precision. Statistical models of vertebral shape and appearance from T4 to L4 were constructed using VFA images from 130 subjects. The resulting models form a part of an algorithm for performing semiautomatic detailed annotation of vertebral bodies from T4 to L4. Algorithm accuracy and precision were evaluated on a test-set of 71 independent images. Overall accuracy was 0.72 mm (3.00% of vertebral height) and overall precision was 0.26 mm (1.11%) for point-to-line distance. Accuracy and precision were best on normal vertebrae (0.65 mm [2.67%] and 0.21 mm [0.90%], respectively) and mild fractures (0.78 mm [3.18%] and 0.32 mm [1.39%], respectively), but accuracy and precision errors were higher for moderate (1.07 mm [4.66%] and 0.48 mm [2.15%], respectively) and severe fractures (2.07 mm [9.65%] and 1.10 mm [5.09%], respectively). Accuracy and precision results for the algorithm were comparable with other reported results in the literature. This semiautomatic image analysis had high overall accuracy and precision on normal vertebrae and mild fractures, but performed less well in moderate and severe fractures. It is, therefore, a useful tool to identify normality of vertebral shape and to identify mild fractures.

Bookmarks Related papers MentionsView impact

Procedings of the British Machine Vision Conference 1994, 1994

Bookmarks Related papers MentionsView impact

Quantification of Brain Function Using PET, 1996

Bookmarks Related papers MentionsView impact

Bone, 2014

Bookmarks Related papers MentionsView impact

Spine, 2013

Study design randomized intra- and inter-reader reproducibility study. To evaluate reproducibilit... more Study design randomized intra- and inter-reader reproducibility study. To evaluate reproducibility of quantitative morphometry (QM) and agreement of dichotomous fracture/no-fracture status on lateral spinal radiographs acquired during routine clinical practice using a clinical workflow tool. Several recent guidelines have underlined the importance of Genant semi-quantitative scoring and selective QM to confirm and grade suspected vertebral fractures in clinical practice. Thoracic and lumbar spine radiographs were acquired from 98 consecutive subjects (mean age, 60.1 ± 11.7 yr) attending the clinic for osteoporosis evaluation. For each subject, QM and Genant semi-quantitative scoring were performed on all evaluable vertebrae from L4 to T4 using a software workflow tool. A radiologist and an experienced radiographical technician performed 2 repeat reading sessions of the radiographs 12 months apart, blinded to each other's results; for the second read, the cases were anonymized and the order was randomized. Inter-reader reproducibility results were 3.1% and 3.2% coefficient of variation (%) for heights, 0.030 and 0.031 root mean square standard deviation for height ratios. For intrareader reproducibility, these values were 2.2% and 3.5% coefficient of variation %; 0.023 and 0.034 root mean square standard deviation. Kappa score results for agreement of dichotomous fracture/no-fracture status were 0.67 and 0.72 (inter-rater) and 0.50 and 0.67 (intrarater). The software assessed in this study is a reliable clinical tool that facilitates QM and Genant semi-quantitative scoring of the spine in routine clinical practice. 3.

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Nuclear Medicine Communications, 1995

Bookmarks Related papers MentionsView impact

Image and Vision Computing, 1994

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Bone, 2010

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Bone, 2014

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