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Papers by Jason Jollimore

Undifferentiated Mesenchymal Neoplasm of the Esophagus in a Child: Case Report and Comparison with Gastrointestinal Stromal Tumor

Pediatric and Developmental Pathology, 2003

Mesenchymal neoplasms of the esophagus are relatively uncommon in adults and exceedingly rare in ... more Mesenchymal neoplasms of the esophagus are relatively uncommon in adults and exceedingly rare in children. Childhood tumors consist almost exclusively of smooth muscle tumors (leiomyomas). We report a case of an undifferentiated mesenchymal neoplasm occurring in the distal esophagus of a 15-year-old boy which is not a gastrointestinal stromal tumor. To our knowledge, this is the first reported case of such a neoplasm occurring in the esophagus of either an adult or child.

The Journal of Organic Chemistry, 1996

... directly bonded to a hydrogen, since there is no inversion of the signal under full NOE, thus... more ... directly bonded to a hydrogen, since there is no inversion of the signal under full NOE, thus ruling out structure 6. A signal at −177.08 ppm in the 15 N spectrum of 5, assigned to the exocyclic nitrogen at C4, does undergo inversion with full NOE, and the ... 1) Vaughan, K. Triazenes ...

The effect of ortho and para substituents on the formation of the E and Z isomers of the arylhydrazones obtained from diazonium coupling with methyl 3-aminocrotonate and 3-aminocrotononitrile

Canadian Journal of Chemistry, 1996

Abstract: Reaction of arene diazonium salts with 3-aminocrotononitrile or methyl 3-aminocrotonate... more Abstract: Reaction of arene diazonium salts with 3-aminocrotononitrile or methyl 3-aminocrotonate affords the 2-aryl-hydrazono-3-oxobutanenitrile (1 or 3 and 3') or the methyl 2-arylhydrazono-3-oxobutanoate (2 and 2' or 4 and 4'). A series of these hydrazones has ...

Formation of methyl 2-arylhydrazono-3-oxobutanoates and 2-arylhydrazono-3-oxobutanenitriles during the coupling reaction of arenediazonium ions with methyl 3-aminocrotonate and 3-aminocrotononitrile

Canadian Journal of Chemistry, 1995

Abstract: Reaction of aryldiazonium salts with methyl 3-arninocrotonate (I) affords high yields o... more Abstract: Reaction of aryldiazonium salts with methyl 3-arninocrotonate (I) affords high yields of the methyl 2-arylhydrazono-3-oxobutanoates (4); analogous diazonium coupling with 3-aminocrotononitrile (2) gives the 2-arylhydrazono-3-oxobutanenitriles (5). The hydrazones are the product of ...

Primary Cutaneous PEComa

The American Journal of Dermatopathology, 2010

A 48-year-old woman attended a physician because of a solitary cutaneous nodule on the left lower... more A 48-year-old woman attended a physician because of a solitary cutaneous nodule on the left lower leg. Microscopic examination of the excisional specimen revealed a dermal tumor composed of nests of epithelioid cells exhibiting clear cytoplasm. They had centrally located vesicular nuclei with distinct nucleoli. A rich network of capillaries was present throughout. The tumor showed an infiltrative border. There was no epidermal involvement. Periodic acid-Shif (PAS) and PAS-Diastase stains demonstrated glycogen deposition within the cytoplasm of the clear cells. Immunohistochemical evaluation revealed that the tumor cells were positive for HMB-45 and microftalmia associated transcription factor (MITF). Focal desmin positivity was also seen. The tumor cells were negative for S-100 protein, alfa smooth muscle actin, HHF-35, and various cytokeratins. The case is one of a primary cutaneous pecoma. Pecomas are rare, recently described mesenchymal tumors composed of perivascular epithelioid cells. They constitute a spectrum of lesions in different organs including angiomyolipoma of the kidney and liver, sugar tumor of the lung, lymphangiomatosis, and lymphangiomyoma. Primary cutaneous PEComas are exceptionally rare and have only recently been recognized. To date, these are approximately 22 cases in the English literature. Follow-up data is limited but they appear to behave in a benign fashion. We report an additional case with the goal of alerting dermatopathologists to this distinctive unusual neoplasm.

Urology, 2002

To assess the presentation and diagnosis of, and treatment options for, multilocular cystic renal... more To assess the presentation and diagnosis of, and treatment options for, multilocular cystic renal cell carcinoma (MCRCC). MCRCC is a rare entity and the true incidence and biologic behavior of MCRCC are not well known. We reviewed the pathology files at the Queen Elizabeth II Health Sciences Centre for a 9-year period (1991 to 2000). All cases of RCC with a cystic component were identified. The clinical features, radiologic features, surgical procedure, pathologic features, and follow-up outcomes of the MCRCC cases were studied. We identified 12 cases of MCRCC comprising 3.1% of the RCC cases. The tumor was incidentally found in 67% of the cases. Ultrasonography was found to be a useful screening test, but computed tomography is the imaging study of choice to identify malignant features. Magnetic resonance imaging can be used in equivocal cases. For treatment, radical nephrectomy was done in 58% and partial nephrectomy in 33%. The mean tumor size was 3.4 cm. The mean solid component of the tumor was 9.5%. The mean tumor grade was 1.1. None of the 10 patients (83%) available for follow-up showed any evidence of recurrence. They were followed up for an average of 42.5 months. MCRCC is an uncommon subtype (3%) of RCC. The term MCRCC should be used exclusively to identify cystic RCC with a small volume (25% or less) of neoplastic clear cells in the cyst walls. The benign clinical course of these lesions suggests that patients may benefit from nephron-sparing surgery.