Jaydip Deb - Academia.edu (original) (raw)

Papers by Jaydip Deb

DOAJ (DOAJ: Directory of Open Access Journals), Mar 31, 2021

The Journal of Obstetrics and Gynecology of India, Feb 22, 2013

International journal of medical research and review, Aug 31, 2019

Introduction: Mediastinum is a "Pandora's box" with many neoplastic and nonneoplastic lesions. Cl... more Introduction: Mediastinum is a "Pandora's box" with many neoplastic and nonneoplastic lesions. Clinico-radiological pattern of mediastinal diseases depends on the size, location and etiology. Hence, non-invasive approach to these cases sometimes leads to diagnostic dilemma. Aims: A prospective study was performed over a 1-year period with the objective of evaluation of diagnostic yields and risk of trans thoracic ultra sound (TTUS) and computed tomography (CT) guided fine-needle aspiration cytology (FNAC) and Tru-cut biopsy along with comparison of cost-effectiveness among mediastinal diseases where clinical and non-invasive imaging could not conclude the diagnosis. Materials and Methods: A prospective study of mediastinal diseases of the adult population without having any diagnosis admitted in a tertiary care hospital in Eastern India was performed after clearance of the ethical committee of the institute. Fifty cases of mediastinal diseases were seen during the study period. One patient sometimes had undergone more than one procedure. The choice of a procedure depended upon the location of the lesion, nature of disease and complication and cost effectiveness ofthe procedures. During the calculation of diagnostic yield of procedure, conclusive results and concordant results to more invasive procedures were considered. Results: Among 50 patients diagnostic yield of TTUS guided FNA and Tru-cut biopsy were 60% and 63.6% respectively. Diagnostic yield of Thoracic CT guided FNA and Tru-cut biopsy were 85% and 92.3% respectively. As a whole TTUS guided invasive procedure and Thoracic CT guided invasive procedure had a diagnostic yield of 61.5% and 87.9% respectively. Complication is less in CT guided invasive procedures (9.1%) compared to Transthoracic USG guided invasive procedures (11.5%) and complication is more common in Tru-Cut biopsy (16.7%) than fine needle aspiration (5.7%). Conclusion: Tru-cut biopsy if applicable is much superior to FNAC for a definite diagnosis of the mediastinal diseases. TTUS guided invasive procedures are very much cost-effective and have added advantage of real time guidance and is comparable with CT guided invasive procedures in respect to risk and diagnostic yields.

PubMed, Apr 1, 2008

Intrathoracic mass lesions, especially peripherally situated masses, often present as a problem a... more Intrathoracic mass lesions, especially peripherally situated masses, often present as a problem as tissue diagnosis is not always possible by cytopathological examination. Cutting needle biopsy may be the method of choice in selected cases for tissue diagnosis. Cutting needle biopsy is indicated for patients with peripherally situated mass lesions abutting chest wall, which are non-vascular and non-cystic in nature.

Lung India, 2011

A 70-years-old male patient was apparently well six months back after which he noticed gradual bl... more A 70-years-old male patient was apparently well six months back after which he noticed gradual blackening of dorsum of both hands and face since last six months. He attended dermatology outpatients department. Dermatologist clinically diagnosed the condition as acanthosis nigricans. He was referred to us for evaluation of any internal malignancy. On systematic questioning, the patient told that he had chronic cough with scanty expectoration for last one year which he ignored as smoker's cough. There was history of three to four episodes of streaky hemoptysis in last one year. He also lost weight significantly in last six months though it was not documented. He was a heavy smoker with 30 pack-years of smoking. He also gave history of low-grade fever occasionally during this period but temperature was not recorded. He had no chest pain, shortness of breath. For these symptoms, he was taking homeopathic medicines without relief. There was one episode of epistaxis 12 months ago. There was no history of hematemesis, vomiting or convulsion. On general survey, his general condition was poor. He had moderate degree pallor and grade II clubbing, pulse rate was 92/min, blood pressure was 110/ 70 mm Hg. There was no palpable lymph node externally. There were hyperpigmented, velvety, rough and rugouse, papillomatous skin lesions symmetrically distributed over arms, armpit, face, neck and hands [Figures 1 and 2]. Examination of respiratory system

PubMed, Feb 1, 2007

A 10 years old girl presented with fever, cough, haemoptysis, dyspnoea on exertion of two months ... more A 10 years old girl presented with fever, cough, haemoptysis, dyspnoea on exertion of two months duration. Chest skiagram and CT-scan of thorax revealed well defined mass lesion of varying density occupying right upper and middle lobes with areas of calcification. On thoracotomy, a huge mass in the right upper lobe was resected and hispathological examination proved it to be a case of plasma cell granuloma.

Indian Journal of Medical Sciences, 2012

Congenital abnormalities of lung are very rare entity, and very often under or misdiagnosed by ph... more Congenital abnormalities of lung are very rare entity, and very often under or misdiagnosed by physicians. The present case, a 12-year boy, who was initially diagnosed as unilateral massive pleural effusion with collapse of lung, and after thorough investigation, including CT scan of thorax, fiber-optic bronchoscopy, and echocardiography, a final diagnosis of unilateral lung hypoplasia was made. So if a teenager present with a unilateral opaque hemithorax in chest X-ray, this entity may be a differential diagnosis.

International Journal of Current Microbiology and Applied Sciences, Feb 10, 2022

Lung India, 2012

A 30-year-old male, carpenter by profession, presented with dry cough and progressive shortness o... more A 30-year-old male, carpenter by profession, presented with dry cough and progressive shortness of breath for two months, right-sided severe chest pain for one and half month and low-grade fever for one month. He had lost two kilograms of weight in the last one month. The patient was a non-smoker, non-alcoholic and non-diabetic. There was no history of similar illness in the family. General examination revealed pallor and raised but non-pulsatile jugular venous pressure. Clubbing was absent and there was no peripheral lymphadenopathy. On examination of the respiratory system features of right hemithoracic volume enlargement were present. Mediastinum (both upper and lower) was grossly shifted to the contralateral side. Percussion note was dull all over the right hemithorax with presence of tenderness on superficial percussion. Anterior de'Espion sign was positive but there was no sternal tenderness. On auscultation, a tubular breath sound was heard near the right infraclavicular area parasternally, in all other areas on the right side vesicular breath sound was markedly diminished. Examination of other systems including the lymphoreticular system and testicular examination were all within normal limits.

Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered i... more Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered in day to day clinical practice. Clinico-epidemiological profile of SP is less well studied in Indian scenario. Objective: to describe sociodemographic correates of pneumothorax, to study the clinical profile and medical causes of SP.

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, Mar 1, 2022

DYSPNEA12score is a reliable method of grading patient perceived dyspnea.The distance covered by ... more DYSPNEA12score is a reliable method of grading patient perceived dyspnea.The distance covered by 6min walk test is used to grade performance capacity.FVC percentage by spirometryisused to assess disease severity in DPLD patient. After taking detailed history and clinical examination 6minute walk test,spirometry,HRCT thorax carried out in all patients with DPLD.Dyspnea score calculated in all patients.Correlation of dyspnea 12 score is made with 6minute walk testndings,spirometric analysis.mild,20% had moderate and24% had severe on dyspnea12score. Study conducted among 50 patients showed 56% patients had mild,20% had moderate and24% had severe on dyspnea12score. By 6MWT 28% patients had normal distance covered(>350m),38% patients had mildly reduced distance(250-349m)covered,12%patients had Moderately reduced distance(150-249m)covered and22%patients Had severely reduced(<149m)distance covered. spirometry analysis showed 28%patients had mild restriction,26%patients had moderate restriction,8%patients had normal spirometry interpretation and 38%patients had severe restriction. Dyspnea12score has positive correlation with 6minute walking distance covered and FVC percentage(by spirometry). Dyspnea12score has positive correlation with 6minute walking distance covered and FVC percentage(by spirometry).

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, Mar 1, 2022

DYSPNEA 12score is a reliable method of grading patient perceived dyspnea. After taking detailed ... more DYSPNEA 12score is a reliable method of grading patient perceived dyspnea. After taking detailed history and clinical examination HRCT thorax carried out in all patients with DPLD. Dyspnea 12 score calculated in all patients. Correlation of dyspnea 12 score is made with the radiological ndings. Study conducted among 50 patients showed 56% patients had mild, 20% had moderate and24% had severe on dyspnea12score. in our study 15(30.0%) patients had ground glass apperance on HRCT. 33(66.0%) patients had reticular pattern in HRCT. 10(20.0%) patients had consolidation in HRCT. 25(50.0%) patients had honey combing on HRCT. 14(28.0%) patients had nodular pattern HRCT. 29(58.0%) patients had traction bronchiectasis on HRCT. .In our study Association between Reticular pattern ,Ground glass appearance ,Consolidation in HRCT with dyspnea 12 score was not statistically signicant. Dyspnea 12 score has positive correlation with honeycombing and traction bronchiectasis on HRCT

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, Mar 1, 2022

Introduction: Image guided per-cutaneous trans-thoracic FNA and Tru-cut biopsy are gaining popula... more Introduction: Image guided per-cutaneous trans-thoracic FNA and Tru-cut biopsy are gaining popularity since last few decades among the pulmonologists for tissue diagnosis of intra-thoracic lesions. These procedures have high diagnostic yield and are less invasive, have less complication rate in comparison to procedures like surgical lung biopsy, bronchoscopy or thoracoscopic guided lung biopsy. Aim: The aim of this prospective observational study was to determine the diagnostic yield and complications of USG guided and CT guided Fine needle aspiration and Tru cut biopsy in cases with intra- thoracic lesions. Materials and methods: In this observational study 49 patients were selected during the one-year study period after getting informed consent. CECT Thorax was done in all cases to evaluate the location, type of lesions. In 14 cases with peripheral pulmonary lesions abutting chest wall and pleural lesions both USG guided FNAC and Tru cut biopsy was done. CT guided FNAC and Tru cut biopsy was done in rest of the 35 cases. Results: Diagnostic yield of USG guided FNAC was found to be 64.3% and CT guided FNAC was 62.86%. Diagnostic yield of CT guided Tru cut biopsy in this study was 91.43% and USG guided Tru cut biopsy was 92.9%. complication rate of both USG and CT guided procedures were low. Conclusion: Both USG guided and CT guided FNAC and Tru cut biopsy are efcient diagnostic procedures for intra-thoracic lesions. Tru-cut biopsy procedure is superior to FNAC procedure for denitive diagnosis

Chest, Oct 1, 2010

There is an array of diagnostic tools available for detection of lung cancer. The optimal approac... more There is an array of diagnostic tools available for detection of lung cancer. The optimal approach is one that leads to a conclusive diagnosis in shortest possible time, with minimal cost and least morbidity.

The Journal of Association of Chest Physicians, 2015

Context: Etiology and clinical spectrum of mediastinal diseases are very wide. Clinico-radiologic... more Context: Etiology and clinical spectrum of mediastinal diseases are very wide. Clinico-radiological pattern of mediastinal diseases depends on the size, location and etiology. Hence, noninvasive approach to these cases sometimes leads to diagnostic dilemma. Aims: We performed a prospective study over a 1-year period with the objective of evaluation of diagnostic yields and risk of trans thoracic ultra sound (TTUS) and computed tomography (CT) guided fine-needle aspiration cytology (FNAC) and Tru-cut biopsy along with comparison of cost-effectiveness among mediastinal diseases where clinical and noninvasive imaging could not conclude the diagnosis. Materials and Methods: A prospective study of mediastinal diseases of the adult population without having any diagnosis admitted in a tertiary care hospital in Eastern India was performed after clearance of the ethical committee of the institute. Fifty cases of mediastinal diseases were seen during the study period. One patient sometimes had undergone more than one procedure. The choice of a procedure depended upon the location of the lesion, need of further detail and patient's financial status. During the calculation of diagnostic yield of procedure, conclusive results and concordant results to more invasive procedures were considered. Statistical Analysis Used: Statistical analysis was performed using MedCalc ® Version 11.3.3.0 for analysis of data. Results: Among 50 patients TTUS guided FNAC were conducted in 26 (52%) occasions and CT guided FNAC were conducted in 26 (52%) occasions. TTUS guided Tru-cut biopsy were done in eight cases (16%), and CT guided Tru-cut biopsy were done in 32 cases (64%). CT guided Tru-cut biopsy had higher diagnostic yield (96.87%) than TTUS guided Tru-cut biopsy (75%). TTUS guided, and CT guided procedures had similar complication rates. Conclusion: Tru-cut biopsy if applicable is much superior to FNAC for a definite diagnosis of the mediastinal diseases. TTUS guided invasive procedures are very much cost-effective and comparable with CT guided invasive procedures in respect to risk and diagnostic yields.

The Indian Journal of Chest Diseases and Allied Sciences

A 33-year-old male presented with repeated episodes of blood-streaked sputum for last one-and hal... more A 33-year-old male presented with repeated episodes of blood-streaked sputum for last one-and half-year. Chest radiograph showed consolidation in the right lower zone. Fibreoptic bronchoscopy revealed an endoluminal growth in the right lower lobe bronchus. Histopathological examination of bronchoscopic biopsy specimen confirmed adenoid cystic carcinoma.

NATIONAL JOURNAL OF LABORATORY MEDICINE

The thoracic cavity consists of the mediastinum located centrally which is bordered by two pleura... more The thoracic cavity consists of the mediastinum located centrally which is bordered by two pleural cavities laterally. The major organs included are the thymus gland, the heart, the lungs, the tracheobronchial tree, lymph nodes and vessels. The lesions originating from the various organs are diverse and occasionally some lesions occurring are extremely rare. The aim was to study demographic features, anatomical site and histological findings of the cases. This was a prospective evaluation of the intrathoracic lesions in a tertiary care center from June 2018 to June 2020. This comprised of patient’s age and sex, the clinical characteristics and location of the tumour, the duration of the lesion and the histopathological findings along with Immunohistochemistry (IHC). This case series describes 10 cases of intrathoracic lesions originating from mediastinal soft tissue, thymus gland, lungs and heart. Patient’s age ranged from five months old to 48 years old with males and females equal...

Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered i... more Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered in day to day clinical practice. Clinico-epidemiological profile of SP is less well studied in Indian scenario. Objective: to describe sociodemographic correates of pneumothorax, to study the clinical profile and medical causes of SP. Method And Materials: a cross sectional descriptive study involving seventy six SP patients treated in inpatient-department of Pulmonary and General Medicine of Bankura Sammilani Medical College & Hospital, West Bengal, India during January 2011 to December 2013 was carried out. Information pertaining to sociodemographics, previous morbidity etc. was gathered by interview using a predesigned and pretested questionnaire. Cinical features of the present morbidity (SP) and its medical causes were established by clinical examination including anthropometry as well as relevant laboratory investigations. Data regarding the treatment modality and the final outcome ...

International Journal of Biomedical and Advance Research, Jun 30, 2014

Neurilemmoma (schwannoma) is a benign, encapsulated perineural tumor of neuroectodermal derivatio... more Neurilemmoma (schwannoma) is a benign, encapsulated perineural tumor of neuroectodermal derivation that originates from the Schwann cells of the neural sheath of motor and sensitive peripheral nerves. Schwannomas are commonly seen in the head and neck region, flexor surface of extremities. However, schwannoma can arise from any cranial or spinal nerve as a globoid encapsulated tumor. We report a case series of four cases of schwannoma arising from four unusual sites one presenting as a parotid tumor ; second one as a p leural mass, third as parapharyngeal mass and the fourth one as a nasal mass.

DOAJ (DOAJ: Directory of Open Access Journals), Mar 31, 2021

The Journal of Obstetrics and Gynecology of India, Feb 22, 2013

International journal of medical research and review, Aug 31, 2019

Introduction: Mediastinum is a "Pandora's box" with many neoplastic and nonneoplastic lesions. Cl... more Introduction: Mediastinum is a "Pandora's box" with many neoplastic and nonneoplastic lesions. Clinico-radiological pattern of mediastinal diseases depends on the size, location and etiology. Hence, non-invasive approach to these cases sometimes leads to diagnostic dilemma. Aims: A prospective study was performed over a 1-year period with the objective of evaluation of diagnostic yields and risk of trans thoracic ultra sound (TTUS) and computed tomography (CT) guided fine-needle aspiration cytology (FNAC) and Tru-cut biopsy along with comparison of cost-effectiveness among mediastinal diseases where clinical and non-invasive imaging could not conclude the diagnosis. Materials and Methods: A prospective study of mediastinal diseases of the adult population without having any diagnosis admitted in a tertiary care hospital in Eastern India was performed after clearance of the ethical committee of the institute. Fifty cases of mediastinal diseases were seen during the study period. One patient sometimes had undergone more than one procedure. The choice of a procedure depended upon the location of the lesion, nature of disease and complication and cost effectiveness ofthe procedures. During the calculation of diagnostic yield of procedure, conclusive results and concordant results to more invasive procedures were considered. Results: Among 50 patients diagnostic yield of TTUS guided FNA and Tru-cut biopsy were 60% and 63.6% respectively. Diagnostic yield of Thoracic CT guided FNA and Tru-cut biopsy were 85% and 92.3% respectively. As a whole TTUS guided invasive procedure and Thoracic CT guided invasive procedure had a diagnostic yield of 61.5% and 87.9% respectively. Complication is less in CT guided invasive procedures (9.1%) compared to Transthoracic USG guided invasive procedures (11.5%) and complication is more common in Tru-Cut biopsy (16.7%) than fine needle aspiration (5.7%). Conclusion: Tru-cut biopsy if applicable is much superior to FNAC for a definite diagnosis of the mediastinal diseases. TTUS guided invasive procedures are very much cost-effective and have added advantage of real time guidance and is comparable with CT guided invasive procedures in respect to risk and diagnostic yields.

PubMed, Apr 1, 2008

Intrathoracic mass lesions, especially peripherally situated masses, often present as a problem a... more Intrathoracic mass lesions, especially peripherally situated masses, often present as a problem as tissue diagnosis is not always possible by cytopathological examination. Cutting needle biopsy may be the method of choice in selected cases for tissue diagnosis. Cutting needle biopsy is indicated for patients with peripherally situated mass lesions abutting chest wall, which are non-vascular and non-cystic in nature.

Lung India, 2011

A 70-years-old male patient was apparently well six months back after which he noticed gradual bl... more A 70-years-old male patient was apparently well six months back after which he noticed gradual blackening of dorsum of both hands and face since last six months. He attended dermatology outpatients department. Dermatologist clinically diagnosed the condition as acanthosis nigricans. He was referred to us for evaluation of any internal malignancy. On systematic questioning, the patient told that he had chronic cough with scanty expectoration for last one year which he ignored as smoker's cough. There was history of three to four episodes of streaky hemoptysis in last one year. He also lost weight significantly in last six months though it was not documented. He was a heavy smoker with 30 pack-years of smoking. He also gave history of low-grade fever occasionally during this period but temperature was not recorded. He had no chest pain, shortness of breath. For these symptoms, he was taking homeopathic medicines without relief. There was one episode of epistaxis 12 months ago. There was no history of hematemesis, vomiting or convulsion. On general survey, his general condition was poor. He had moderate degree pallor and grade II clubbing, pulse rate was 92/min, blood pressure was 110/ 70 mm Hg. There was no palpable lymph node externally. There were hyperpigmented, velvety, rough and rugouse, papillomatous skin lesions symmetrically distributed over arms, armpit, face, neck and hands [Figures 1 and 2]. Examination of respiratory system

PubMed, Feb 1, 2007

A 10 years old girl presented with fever, cough, haemoptysis, dyspnoea on exertion of two months ... more A 10 years old girl presented with fever, cough, haemoptysis, dyspnoea on exertion of two months duration. Chest skiagram and CT-scan of thorax revealed well defined mass lesion of varying density occupying right upper and middle lobes with areas of calcification. On thoracotomy, a huge mass in the right upper lobe was resected and hispathological examination proved it to be a case of plasma cell granuloma.

Indian Journal of Medical Sciences, 2012

Congenital abnormalities of lung are very rare entity, and very often under or misdiagnosed by ph... more Congenital abnormalities of lung are very rare entity, and very often under or misdiagnosed by physicians. The present case, a 12-year boy, who was initially diagnosed as unilateral massive pleural effusion with collapse of lung, and after thorough investigation, including CT scan of thorax, fiber-optic bronchoscopy, and echocardiography, a final diagnosis of unilateral lung hypoplasia was made. So if a teenager present with a unilateral opaque hemithorax in chest X-ray, this entity may be a differential diagnosis.

International Journal of Current Microbiology and Applied Sciences, Feb 10, 2022

Lung India, 2012

A 30-year-old male, carpenter by profession, presented with dry cough and progressive shortness o... more A 30-year-old male, carpenter by profession, presented with dry cough and progressive shortness of breath for two months, right-sided severe chest pain for one and half month and low-grade fever for one month. He had lost two kilograms of weight in the last one month. The patient was a non-smoker, non-alcoholic and non-diabetic. There was no history of similar illness in the family. General examination revealed pallor and raised but non-pulsatile jugular venous pressure. Clubbing was absent and there was no peripheral lymphadenopathy. On examination of the respiratory system features of right hemithoracic volume enlargement were present. Mediastinum (both upper and lower) was grossly shifted to the contralateral side. Percussion note was dull all over the right hemithorax with presence of tenderness on superficial percussion. Anterior de'Espion sign was positive but there was no sternal tenderness. On auscultation, a tubular breath sound was heard near the right infraclavicular area parasternally, in all other areas on the right side vesicular breath sound was markedly diminished. Examination of other systems including the lymphoreticular system and testicular examination were all within normal limits.

Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered i... more Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered in day to day clinical practice. Clinico-epidemiological profile of SP is less well studied in Indian scenario. Objective: to describe sociodemographic correates of pneumothorax, to study the clinical profile and medical causes of SP.

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, Mar 1, 2022

DYSPNEA12score is a reliable method of grading patient perceived dyspnea.The distance covered by ... more DYSPNEA12score is a reliable method of grading patient perceived dyspnea.The distance covered by 6min walk test is used to grade performance capacity.FVC percentage by spirometryisused to assess disease severity in DPLD patient. After taking detailed history and clinical examination 6minute walk test,spirometry,HRCT thorax carried out in all patients with DPLD.Dyspnea score calculated in all patients.Correlation of dyspnea 12 score is made with 6minute walk testndings,spirometric analysis.mild,20% had moderate and24% had severe on dyspnea12score. Study conducted among 50 patients showed 56% patients had mild,20% had moderate and24% had severe on dyspnea12score. By 6MWT 28% patients had normal distance covered(>350m),38% patients had mildly reduced distance(250-349m)covered,12%patients had Moderately reduced distance(150-249m)covered and22%patients Had severely reduced(<149m)distance covered. spirometry analysis showed 28%patients had mild restriction,26%patients had moderate restriction,8%patients had normal spirometry interpretation and 38%patients had severe restriction. Dyspnea12score has positive correlation with 6minute walking distance covered and FVC percentage(by spirometry). Dyspnea12score has positive correlation with 6minute walking distance covered and FVC percentage(by spirometry).

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, Mar 1, 2022

DYSPNEA 12score is a reliable method of grading patient perceived dyspnea. After taking detailed ... more DYSPNEA 12score is a reliable method of grading patient perceived dyspnea. After taking detailed history and clinical examination HRCT thorax carried out in all patients with DPLD. Dyspnea 12 score calculated in all patients. Correlation of dyspnea 12 score is made with the radiological ndings. Study conducted among 50 patients showed 56% patients had mild, 20% had moderate and24% had severe on dyspnea12score. in our study 15(30.0%) patients had ground glass apperance on HRCT. 33(66.0%) patients had reticular pattern in HRCT. 10(20.0%) patients had consolidation in HRCT. 25(50.0%) patients had honey combing on HRCT. 14(28.0%) patients had nodular pattern HRCT. 29(58.0%) patients had traction bronchiectasis on HRCT. .In our study Association between Reticular pattern ,Ground glass appearance ,Consolidation in HRCT with dyspnea 12 score was not statistically signicant. Dyspnea 12 score has positive correlation with honeycombing and traction bronchiectasis on HRCT

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, Mar 1, 2022

Introduction: Image guided per-cutaneous trans-thoracic FNA and Tru-cut biopsy are gaining popula... more Introduction: Image guided per-cutaneous trans-thoracic FNA and Tru-cut biopsy are gaining popularity since last few decades among the pulmonologists for tissue diagnosis of intra-thoracic lesions. These procedures have high diagnostic yield and are less invasive, have less complication rate in comparison to procedures like surgical lung biopsy, bronchoscopy or thoracoscopic guided lung biopsy. Aim: The aim of this prospective observational study was to determine the diagnostic yield and complications of USG guided and CT guided Fine needle aspiration and Tru cut biopsy in cases with intra- thoracic lesions. Materials and methods: In this observational study 49 patients were selected during the one-year study period after getting informed consent. CECT Thorax was done in all cases to evaluate the location, type of lesions. In 14 cases with peripheral pulmonary lesions abutting chest wall and pleural lesions both USG guided FNAC and Tru cut biopsy was done. CT guided FNAC and Tru cut biopsy was done in rest of the 35 cases. Results: Diagnostic yield of USG guided FNAC was found to be 64.3% and CT guided FNAC was 62.86%. Diagnostic yield of CT guided Tru cut biopsy in this study was 91.43% and USG guided Tru cut biopsy was 92.9%. complication rate of both USG and CT guided procedures were low. Conclusion: Both USG guided and CT guided FNAC and Tru cut biopsy are efcient diagnostic procedures for intra-thoracic lesions. Tru-cut biopsy procedure is superior to FNAC procedure for denitive diagnosis

Chest, Oct 1, 2010

There is an array of diagnostic tools available for detection of lung cancer. The optimal approac... more There is an array of diagnostic tools available for detection of lung cancer. The optimal approach is one that leads to a conclusive diagnosis in shortest possible time, with minimal cost and least morbidity.

The Journal of Association of Chest Physicians, 2015

Context: Etiology and clinical spectrum of mediastinal diseases are very wide. Clinico-radiologic... more Context: Etiology and clinical spectrum of mediastinal diseases are very wide. Clinico-radiological pattern of mediastinal diseases depends on the size, location and etiology. Hence, noninvasive approach to these cases sometimes leads to diagnostic dilemma. Aims: We performed a prospective study over a 1-year period with the objective of evaluation of diagnostic yields and risk of trans thoracic ultra sound (TTUS) and computed tomography (CT) guided fine-needle aspiration cytology (FNAC) and Tru-cut biopsy along with comparison of cost-effectiveness among mediastinal diseases where clinical and noninvasive imaging could not conclude the diagnosis. Materials and Methods: A prospective study of mediastinal diseases of the adult population without having any diagnosis admitted in a tertiary care hospital in Eastern India was performed after clearance of the ethical committee of the institute. Fifty cases of mediastinal diseases were seen during the study period. One patient sometimes had undergone more than one procedure. The choice of a procedure depended upon the location of the lesion, need of further detail and patient's financial status. During the calculation of diagnostic yield of procedure, conclusive results and concordant results to more invasive procedures were considered. Statistical Analysis Used: Statistical analysis was performed using MedCalc ® Version 11.3.3.0 for analysis of data. Results: Among 50 patients TTUS guided FNAC were conducted in 26 (52%) occasions and CT guided FNAC were conducted in 26 (52%) occasions. TTUS guided Tru-cut biopsy were done in eight cases (16%), and CT guided Tru-cut biopsy were done in 32 cases (64%). CT guided Tru-cut biopsy had higher diagnostic yield (96.87%) than TTUS guided Tru-cut biopsy (75%). TTUS guided, and CT guided procedures had similar complication rates. Conclusion: Tru-cut biopsy if applicable is much superior to FNAC for a definite diagnosis of the mediastinal diseases. TTUS guided invasive procedures are very much cost-effective and comparable with CT guided invasive procedures in respect to risk and diagnostic yields.

The Indian Journal of Chest Diseases and Allied Sciences

A 33-year-old male presented with repeated episodes of blood-streaked sputum for last one-and hal... more A 33-year-old male presented with repeated episodes of blood-streaked sputum for last one-and half-year. Chest radiograph showed consolidation in the right lower zone. Fibreoptic bronchoscopy revealed an endoluminal growth in the right lower lobe bronchus. Histopathological examination of bronchoscopic biopsy specimen confirmed adenoid cystic carcinoma.

NATIONAL JOURNAL OF LABORATORY MEDICINE

The thoracic cavity consists of the mediastinum located centrally which is bordered by two pleura... more The thoracic cavity consists of the mediastinum located centrally which is bordered by two pleural cavities laterally. The major organs included are the thymus gland, the heart, the lungs, the tracheobronchial tree, lymph nodes and vessels. The lesions originating from the various organs are diverse and occasionally some lesions occurring are extremely rare. The aim was to study demographic features, anatomical site and histological findings of the cases. This was a prospective evaluation of the intrathoracic lesions in a tertiary care center from June 2018 to June 2020. This comprised of patient’s age and sex, the clinical characteristics and location of the tumour, the duration of the lesion and the histopathological findings along with Immunohistochemistry (IHC). This case series describes 10 cases of intrathoracic lesions originating from mediastinal soft tissue, thymus gland, lungs and heart. Patient’s age ranged from five months old to 48 years old with males and females equal...

Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered i... more Background: Spontaneous pneumothorax (SP) is one of the common acute chest problems encountered in day to day clinical practice. Clinico-epidemiological profile of SP is less well studied in Indian scenario. Objective: to describe sociodemographic correates of pneumothorax, to study the clinical profile and medical causes of SP. Method And Materials: a cross sectional descriptive study involving seventy six SP patients treated in inpatient-department of Pulmonary and General Medicine of Bankura Sammilani Medical College & Hospital, West Bengal, India during January 2011 to December 2013 was carried out. Information pertaining to sociodemographics, previous morbidity etc. was gathered by interview using a predesigned and pretested questionnaire. Cinical features of the present morbidity (SP) and its medical causes were established by clinical examination including anthropometry as well as relevant laboratory investigations. Data regarding the treatment modality and the final outcome ...

International Journal of Biomedical and Advance Research, Jun 30, 2014

Neurilemmoma (schwannoma) is a benign, encapsulated perineural tumor of neuroectodermal derivatio... more Neurilemmoma (schwannoma) is a benign, encapsulated perineural tumor of neuroectodermal derivation that originates from the Schwann cells of the neural sheath of motor and sensitive peripheral nerves. Schwannomas are commonly seen in the head and neck region, flexor surface of extremities. However, schwannoma can arise from any cranial or spinal nerve as a globoid encapsulated tumor. We report a case series of four cases of schwannoma arising from four unusual sites one presenting as a parotid tumor ; second one as a p leural mass, third as parapharyngeal mass and the fourth one as a nasal mass.