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Papers by Jean KABORE

International Journal of Epilepsy

Background Epilepsy is a common and chronic neurological disorder influencing children's cogn... more Background Epilepsy is a common and chronic neurological disorder influencing children's cognitive and behavioral performance. Primary caregivers of children with epilepsy (CWE) report high levels of depression and anxiety. Patients and Methods We performed a cross-sectional study on caregivers of CWE in the Neurology Department of Yalgado Ouédraogo University Teaching Hospital from May 7, 2020 to August 18, 2020. The State-Trait Anxiety Inventory scale and Beck Depression Inventory scale were assessed to screen anxiety and depression. Results One hundred caregivers with a mean age of 37.75 ± 10.69 years were included in the study. The majority of them were female gender (73%), aged <40 years (59%), and residing in rural areas (79%). Most of caregivers were female gender (73%) and the mothers of children (67%). The majority of CWE were boys (55%), having generalized epilepsy (55%) and epilepsy duration less than 6 years (74%). Anxiety was observed in 56%, depression in 27%, a...

African & Middle East Epilepsy Journal, 2020

Conflits d'intérêt : Aucun. Résumé : Introduction : L'état de mal épileptique (EME) est la forme ... more Conflits d'intérêt : Aucun. Résumé : Introduction : L'état de mal épileptique (EME) est la forme la plus grave de l'épilepsie, du fait de sa lourde mortalité et de son pronostic fonctionnel encore péjoratif, en particulier en Afrique Subsaharienne. Afin de contribuer à inverser cette tendance, nous avons réalisé la présente étude dans le but de déterminer les aspects cliniques, étiologiques et pronostiques des états de mal épileptiques, dans un hôpital de référence à Ouagadougou, au Burkina Faso. Méthodologie : Il s'est agi d'une étude prospective transversale descriptive et analytique, menée de janvier 2015 à juillet 2019. L'étude a porté sur les patients hospitalisés au Centre Hospitalier Universitaire de Tingandogo, à Ouagadougou pour EME durant la période d'étude. Les caractéristiques sociodémographiques, cliniques, paracliniques, étiologiques et évolutives des patients ont été analysées. Une analyse bivariée a permis d'identifier les liens entre les caractéristiques des patients et la mortalité intra hospitalière, avec p < 0.05 comme seuil de signification statistique. Résultats : Nous avons colligé 60 cas. Dans 76.6% des cas, l'EME est survenu chez des patients qui n'avaient pas antécédents d'épilepsie. L'EME convulsif tonicoclonique généralisé d'emblée et l'EME focal avec bilatéralisation convulsive ont été les formes cliniques les plus fréquentes avec respectivement 41.4% et 25.9%. La durée moyenne de l'épisode d'EME était de 27 +/-43 heures. Les étiologies aigues avec 76.7% des cas ont été les plus représentées ; elles étaient dominées par les causes infectieuses aigues (46.7%) et cérébrovasculaires aigues (15 %). Les étiologies subaiguës ou séquellaires ont représenté 23.3% avec principalement des séquelles d'AVC et de traumatisme crânien. La durée moyenne d'hospitalisation était de 12.3 jours. A l'issue de l'hospitalisation, 15% des patients avaient un handicap sévère et 13.3 % étaient décédés. Une durée d'hospitalisation > 10 jours (p=0.04) et une étiologie infectieuse (p=0.03), étaient associées à une augmentation de la mortalité intra hospitalière. Conclusion : le profil clinique des EME est dominé par les formes tonico clonique d'emblée et focale avec bilatéralisation convulsive secondaire. Les infections aigues du SNC ou systémiques et les lésions cérébrales non aigües ou séquellaires en sont les principales étiologies. Le pronostic précoce reste défavorable. Les EME prolongés et les causes infectieuses augmentent les risques de décès précoce. La lutte contre les maladies infectieuses et une prise en charge précoce et adéquate des EME, contribueront à réduire l'ampleur de cette affection en Afrique sub saharienne. Mots-clés : EME convulsif-infections aigues du SNC-Glasgow Outcome Score (GOS).

Acta Epileptologica, 2022

Background Epilepsy is the most common neurological disease in the world. The objective of the st... more Background Epilepsy is the most common neurological disease in the world. The objective of the study was to determine the knowledge, attitude and practice of driver’s license applicants and instructors in driving schools on epilepsy in Burkina Faso. Method This cross-sectional study was carried out from January 7th to March 7th 2020 in 21 driving schools approved by the National Driver License Authority in the city of Ouagadougou. Fifteen driver applicants and one instructor were selected in each driving school, resulting in a total of 315 driver applicants and 21 instructors in the study. Results The mean age of participants was 29.91 ± 7.63 years. One of the driver applicants included in the study was once experienced a seizure attack. All respondents had heard of epilepsy. The main source of epilepsy information was from family (42.5%). Two hundred and twenty-six respondents (67.3%) had witnessed an epileptic seizure. A majority of participants (55.9%) believed that persons with ...

Background Children with epilepsies (CWE) show an increased prevalence of comorbid depressive and... more Background Children with epilepsies (CWE) show an increased prevalence of comorbid depressive and anxiety disorders.Patients and Methods We conducted a cross-sectional study on children with epilepsy aged 7 to 19 years attending neurology consultations at YOUTH during the period from May 06 to August 6, 2019. STAIc Anxiety Scale and Child Depression Inventory were performed in all the patients. Results: The mean age of children with epilepsy was 10.86 ± 3.30 years with male predominance. The mean STAIc score was 34.71 ± 6.58. Anxiety was observed in 42.2% of cases with male predominance. Anxiety was mild to moderate in 42.2% of cases. The risk factors for anxiety were the educational status (p-0.01) and epilepsy duration (p-0.02). The mean CDI score was 11.66 ± 5.76. Depression symptoms were observed in 26.7% of patients. Mild depression was present in all of cases. The risk factors for depression were the level of education (p = 0.01) and the duration of epilepsy (p = 0.008).Conclu...

Annals of Medical and Health Sciences Research, 2018

Objective: To describe clinical features of the first diagnosed case of dysferlinopathy in Burkin... more Objective: To describe clinical features of the first diagnosed case of dysferlinopathy in Burkina Faso. Clinical observation: This is a 33-year-old Burkinabe married patient, born from a non-consanguineous polygamous family of 37 children. Disease onset was when the patient was 24 years; he experienced weakness of the 2 lower limbs with gait disorders, balance and painful muscle cramps. There was apparent muscle weakness at a level of 3/5 in the proximal muscles on neurological examination; no weakness of the distal muscles, pathological reflex, or cranial findings. CK level was increased to 24,414 U/L (0-248). Echocardiography was found left ventricular hypertrophy. Muscle MRI of the shoulders, pelvis and limbs founded diffuse amyotrophy. Immuno-histo-chemestry in Italy revealed sarcoglycannopathy. Western blot from blood samples and genetics were performed in France and revealed dysferlinopathy. Since 2009, he was treated with corticosteroid the CK levels temporarily decreased to...

Objective: To describe cognitive disorders in patients with epilepsy attending neurology consulta... more Objective: To describe cognitive disorders in patients with epilepsy attending neurology consultations in the city of Ouagadougou. Methodology: This was a prospective cross-sectional multicenter study carried on patients with epilepsy during the period from 1er January 2018 to 30 April 2019. All the patients were screened using mini-mental state examination (MMSE). Results: The study included 102 patients with a mean age of 33.28 ± 15.55 years. The sample was consisted of 54 (52.9%) men and 48 (47.1%) women. The majority of patients had secondary level (55.7 %). Generalized seizures were more common (74.5%). The most common causes of epilepsy was head trauma (24.5%). A great number of patients were treated by phenobarbital (49%). The overall mean MMSE score was 25.65 ± 5.07. The frequency of cognitive disorders was 61.8%, including cognitive impairment (25.5%), mild dementia (25.5%), moderate dementia (7.8%) and severe dementia (3%). The domains most affected were calculation and attention defi cit (48%) followed by memory disorders (27.5%) and copying (12.8%). Head trauma and phenobarbital were signifi cantly associated to cognitive. Cognitive disorders were less frequent in young adult aged of 26-35 years. Conclusion: Cognitive disorders are common in adult patients with epilepsy using MMSE. Their screening in adults must be early for appropriate management.

Pain Research and Management, 2021

Background. Migraine is a common neurological disorder characterized by severe headache attacks t... more Background. Migraine is a common neurological disorder characterized by severe headache attacks that may be debilitating. The objective of this study is to determine the knowledge and attitudes of general practitioners in the hospital districts of the city of Ouagadougou on migraine. Methods. This cross-sectional study was carried out in hospital districts of Ouagadougou. The data were collected during three months from February 1 to April 30, 2020. Results. The study included 116 general practitioners. Thirteen percent of them were suffering from migraine. All participants had previous experience with migraine diagnosis before the survey. Eighty percent of general practitioners had a good level of knowledge of ICDH-3 criteria (knowing 6-7 criteria). The most widely recognized IHS criteria were pulsatility quality (93.1%), photophobia or sonophobia (80.2%), and mild-to-moderate intensity (80%). Ninety-five (81.9%) general practitioners rarely ordered brain imaging. The most common a...

Tropical Diseases, Travel Medicine and Vaccines, 2021

Background Snake bites remain a major medical problem in West Africa, and hemorrhagic stroke foll... more Background Snake bites remain a major medical problem in West Africa, and hemorrhagic stroke following a snakebite has emerged as a rare secondary condition. The objective of this study was to determine the neurological complications following snake bite. Methods This study included all the cases of hemorrhagic stroke following snake bite admitted in the neurology Department of Yalgado Ouedraogo University Teaching Hospital during the period from January 1st, 2018 to December 31st 2019. Results Three cases of hemorrhagic stroke following snake bite were included in the study. The strokes occurred 4–15 days after the snakebite. Traditional treatment was applied in two cases. Complications were significant, including local manifestations and severe anemia in 2 patients who received blood transfusion. Snake anti-venom was applied. At admission, motor deficit, conscience disorders and fever were the most frequent complaints. Patients received repeated dose of snake anti-venom was applie...

Journal of Neurology and Neurobiology, 2020

Volume 6-Issue 1 of this study is to determine the characteristics of ischemic stroke in Women an... more Volume 6-Issue 1 of this study is to determine the characteristics of ischemic stroke in Women and to compare vascular risk factors, stroke severity and clinical outcome between patients aged under and older 50 years in a tertiary hospital in Burkina Faso. Methodology Study area Burkina Faso is a French speaking country in West Africa region. It covers an area of 274,200 square kilometers with an estimated population of 19,632,147 inhabitants in 2017. The country currently has 5 national Teaching University hospitals, including the first, the Yalgado Ouedraogo hospital in Ouagadougou. In this hospital, stroke management is provided by the emergency department, the resuscitation unit, the neurology department and the cardiology department. The neurology department consists of 3 neurologists and 15 residents in neurology. Its capacity of reception is of 23 beds.

Stroke Research and Treatment, 2020

Objective. To determine the prevalence of ischemic stroke deaths and their predictive factors in ... more Objective. To determine the prevalence of ischemic stroke deaths and their predictive factors in the Emergency Department at Yalgado Ouedraogo University Teaching Hospital (YOUTH). Methodology. This was a retrospective study with an analytical and descriptive focus over a period of three years from January 1, 2015, to December 31, 2017. Results. During the study period, 302 acute ischemic stroke patients with a mean age of 62.2±14.26 years were included. Atrial hypertension was the most common vascular risk factor in 52.5%. On admission, 34.8% of patients had loss of consciousness. The mean time to perform brain CT was 1.5 days. The average length of stay was 4 days. Electrocardiogram, echocardiography, and cervical Doppler were not performed during hospitalization in ED. The mortality rate was 39%, respectively, 37.6% in male and 41.6% in female. The mean age of patients who died in ED was 63.6±13.52 years. Hypertension was the most common vascular risk factors in 54.2% of death. A...

World Journal of Neuroscience, 2020

Objective: To describe the clinical and etiological characteristics of hemiplegia in the northern... more Objective: To describe the clinical and etiological characteristics of hemiplegia in the northern region of Burkina Faso. Methodology: This was transversal with a descriptive and analytical study of one hundred and ninety-six hemiplegic patients in charge of general medicine at the Ouahigouya Regional University Hospital from November 2015 to November 2017. Results: The majority of patients had a brutal hemiplegia predominant on the right. The sample consisted mainly of male patients with a mean age of 58 years. High blood pressure was the main factor of vascular risk. The cerebrovascular accident (58.7%) was the main pathology diagnosed. Most patients received symptomatic management. Physiotherapy was performed in 29.6% of patients. The clinical outcome at discharge was marked by the persistence of hemiplegia in more than 90.8% of patients. There was an improvement in the average MIF score at the exit. Conclusion: The lack of computed tomography and neuro-resuscitation unit were the main factors limiting the management of hemiplegia in our context.

World Journal of Neuroscience, 2019

Objective: To determine the prevalence and risk factors of carotid atherosclerosis among ischemic... more Objective: To determine the prevalence and risk factors of carotid atherosclerosis among ischemic stroke patients in a tertiary hospital in Burkina Faso. Methodology: This was a descriptive and analytical retrospective study of patients admitted at neurology department of Yalgado Ouedraogo University Teaching Hospital with ischemic stroke and cerebral large vessel atherosclerosis in the period from January 1, 2012 to December 31, 2016. Results: The prevalence of extracranial carotid atherosclerosis was 23.9%. The mean age of patients was 63.5 years (Range 31-90 years). The study population included 65% of men and 35% of women. Hypertension was the most common vascular risk factor (75.6%). Stroke was mostly located in the anterior circulation in 23.9%. Low HDL-C was present in 52% of patients. The majority of plaque was homogeneous (85.2%). Plaque were located in carotid bulbar artery (38.5%) followed by common carotid artery (28.2%) and extracranial internal carotid artery (18.6%). According to cerebral lesion, plaque was bilateral in 45.5%, ipsilateral in 42.3% and contralateral in 12.1% of cases. Tight stenosis was found in 30.1% of patients. There was a significant link between male gender and tight stenosis (p = 0.004). Aspirin was the most antiplatelet therapy used (95.5%). Statin therapy was used in 91% of patients. The mean duration of hospitalization was 12.5 days with a mortality rate of 7.1%. Conclusions: Our study showed that extra carotid atherosclerosis was the most common cause of ischemic stroke in Burkina Faso. Man gender was most represented than women.

Open Journal of Depression, 2019

Background: Depression is the most common psychiatric disorder in patients with epilepsy. The aim... more Background: Depression is the most common psychiatric disorder in patients with epilepsy. The aim of this study was to determine the prevalence of depressive symptoms and its factors associated in patients with epilepsy at the Yalgado Ouedraogo University Teaching Hospital (Burkina Faso). Methods: This was a prospective 6-month study carried out in Neurology Department from February to July 2017. This study included all the patients with epilepsy aged over 18 years. Sampling was non-random with systematic recruitment. The informed consent of the patient was required. All included patients were assessed using the Hamilton Depression Scale and Gererd questionnaire. The analysis of the data was performed by the software Epi Info version 7. Results: One hundred two patients with epilepsy with a mean age of 41.47 ± 16.67 years were included. The symptoms of depression were present in 67.3% of patients with epilepsy with a mean age of 42.59 ± 17 years, and 78 years (19-88 years). Depression was mild in 35%, moderate in 34% and severe in 31%. The prevalence of depressive symptoms was respectively 57.6% in male patients and 79% in female gender. The mean score of HDRS for depression was 15.62 ± 4.26. Hypochondriasis (97%), work and interest (95.5%) and anxiety-somatic (94.1%) were the most symptoms of HDRS-17. Higher scores were found for work and interests, anxiety-psychic and hypochondriasis. There was a significant association between perceived stigma, female gender, seizure frequency and presence of depression among patients with epilepsy (p < 0.05). Conclusion: Our study had found a high prevalence of depression among patients with epilepsy. High perceived stigma, female How to cite this paper: Dabilgou, A. A.,

Journal of Epileptology, 2021

Background. Epilepsy is one of the most common pediatric neurological disorders. The knowledge an... more Background. Epilepsy is one of the most common pediatric neurological disorders. The knowledge and attitude of teachers toward epileptic students can be crucial. Patients and methods. This cross-sectional study was carried on schoolteachers in the city of Ouagadougou during the period from March 02 to July 20, 2020. The schools were chosen randomly among a list of recognized public or private establishments. Results. Two hundred and twenty teachers were included in the study. Among them, 35.45% were post-primary teachers. Most of them had already heard of epilepsy (98.6%). For the majority of school teachers, epilepsy was not a contagious disease (74%). Regarding the causes of epilepsy, the majority of participants had listed brain disease (65%) and genetic disorders (18.20%). The majority of schoolteachers (70.9%) believed that students with epilepsy usually had associated mental retardation. For the majority of teachers (73.20%), epilepsy was a stigmatizing disease, and students with epilepsy should benefit from personalized supervision (65%). The majority of schoolteachers (75.9%) had a good knowledge of epilepsy, and 43.6% had good attitudes toward epilepsy. The factor associated with teachers' knowledge was having witnessed an epileptic seizure (p < 0.05). The factors related to schoolteacher practice was gender (p < 0.05) and having already witnessed an epileptic seizure (p < 0.05) Conclusion. Our study found that teachers had a good knowledge of epilepsy, but attitudes and practices were inadequate.

Rheumatology International, 2011

To study the prevalence and semiotic characteristics of neuropathic pain in the common low back p... more To study the prevalence and semiotic characteristics of neuropathic pain in the common low back pain to the Black African subject. This was a prospective crosssectional survey carried on from April 1 2009 to August 31 2009 in consultations of rheumatology, neurology, and neurosurgery at the University Hospital Yalgado Ouédraogo in Ouagadougou (Burkina Faso). All patients with a low back pain or a common lomboradiculalgie were included. DN4 questionnaire was used for the diagnosis of neuropathic pain. One hundred and seven patients have been recruited during the study period; Sixty-four (59.80%) were female (sex ratio M/F: 0.67). The average age was 34.11 § 13.46 years of age with extremes of 20 and 79. The average duration of disease was 48.53 months with extremes of 10 days and 50 years. Eighty-seven patients (81.31%) had a disease duration, which was 3 months longer. Sixty-six patients (61.70%) had a predominant lomboradiculalgie; among the remaining 41, low back pain predominated. Average intensity of pain was 62.81 § 22.43 (on a scale of 100). A sign of Lasèque was present in the 41 (38.30%) patients. Fifty-three (49.5%) patients had a neuropathic pain. The prevalence of neuropathy signs according to the DN4 questionnaire was as follows: burning (n = 37; 34.58%), painful cold (n = 13; 12.15%), electric shocks (n = 31; 38.97%), pins and needles (n = 34; 31.77%), tingling (n = 35; 32.71%), numbness (n = 45; 42.05%), itching (n = 18; 16.82%), touch hypoesthesia (n = 35; 32.71%), pinprick (n = 33; 30.84%), and tactile allodynia (n = 21; 19.62%). Among the studied variables, the presence of a radiculalgy was statistically associated with neuropathic pain. The lomboradiculalgie of the Black African subject associates neuropathic pain observed in half of patients. Treatment must therefore always take account of this association. However, further studies are needed before any deWnitive conclusion.

SN Comprehensive Clinical Medicine, 2020

To determine the frequency of chronic headache in a population of patients attending to neurology... more To determine the frequency of chronic headache in a population of patients attending to neurology consultation. This prospective cross-sectional study was carried on patients with chronic headaches attending at neurology consultation of YOUTH. This study was conducted in 3 months in the Neurology Department of Ouagadougou YOUTH from October 10, 2017 to January 10, 2018. One hundred and two patients (mean age 41.2 ± 16.1 years, 61.8% of women) with headache were included during study period. The majority of patients (56.9%) had previous medical or nursing consultations. Of them, 76.5% had received prior medical treatment. The most common past medical history was cranial trauma (21.6%) followed by hypertension (18.6%) and dental diseases (16.7%). The mean duration of headache was 52.5 ± 32.7 months (ranges 3-273 months). The majority of patients (85.4%) had episodic headaches. Primary headaches were the most common cause of headache (52.9%), including tension-type headaches (51.8%) and migraine (38.9%). Headache had major impact on the quality of life of patients with migraine (44.5%) and patients with TTH (54.2%). Headache was frequent in Neurology Department. Primary headaches are the most common types of headache dominated by tension-type headaches and migraine.

Une étude épidémiologique sur les handicaps chroniques à la marche a été effectuée de Novembre 19... more Une étude épidémiologique sur les handicaps chroniques à la marche a été effectuée de Novembre 1988 à Janvier 1989 en zone rurale dans trois provinces du Burkina Faso. Le recrutement réalisé au porte à porte montre que le taux de prévalence des handicaps chroniques à la marche dépasse 9 pour mille habitants. La poliomyélite occupe le premier rang des étiologies avec un tiers des cas, suivie de l'ensemble des autres maladies neurologiques, les affections rhumatologiques et orthopédiques, et surtout les séquelles de dracunculose. Contraitement à d'autres études réalisées en milieu urbain, le rôle des sciatites par injection médicamenteuse intrafessière est négligeable dans les régions rurales faiblement médicalisées. Le rôle de certaines affections neurologiques telles les paraparésies spastiques tropicales reste à déterminer. (Résumé d'auteur)

Results: Out of a total of 554 cases, 232 (41.88%) tested positive for COVID-19 with a median age... more Results: Out of a total of 554 cases, 232 (41.88%) tested positive for COVID-19 with a median age of 29 years (14 days-100 years). Among the positives, 130 (56.03%) were men, for a sex ratio (M/F) of 1.3. Factors independently associated with COVID-19 were Ocass market attendance (ORa=4.35; 95% CI =[2.38-7.94], p <0.001), urban versus rural residence (ORa =2.77; 95% CI =[1.39-5.53], p=0.005), contact with a positive case (ORa =3.05; 95% CI =[2.134.35], p <0.001), participation at a ceremony (ORa=2.40; 95% CI=[1.03-5.59], p <0.001).

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Bulletin de la Societe de pathologie exotique, 2009

Neurocysticercosis (NCC) frequently appears by seizures following parenchymatous location of ency... more Neurocysticercosis (NCC) frequently appears by seizures following parenchymatous location of encysted worms of Taenia solium. We report a case of NCC revealed by a Wallenberg's syndrome. A man of 44 years old, without any cardiovascular risk factor was admitted at the neurology department of Yalgado-Ouédraogo hospital in Ouagadougou for an abrupt onset of vertigos, recurrent falls on the right side, hiccough, and deglutition weakness. The clinical examination found a blood pressure at 130 mmHg/80 mmHg, a CMI at 24, a Wallenberg's syndrome. The CT scan showed a laterobulbar lacunar infarct with punctiform calcifications of cerebellum, third ventricle, frontal, right temporal, occipital and left parietal lobes. The CSF showed a raise of cells number at 23 lymphocytic elements, proteins rose to 1.5 g/l, glucose and chloride were normal. Cysticercosis blood and CSF serologies were positive. The blood cells count showed only an eosinophilia and the blood sedimentation rate reache...