Jean-Pierre Guillon - Academia.edu (original) (raw)
Papers by Jean-Pierre Guillon
International Contact Lens Clinic, 1991
This study investigated the effect of variations in fluorine concentration, varied in a fixed rel... more This study investigated the effect of variations in fluorine concentration, varied in a fixed relationship with the hydrophilic monomers 20, 30, and 40% by weight, of fluorosilicone acrylate RGP polymers on tear film, lens wettability, and deposit resistance. Precomeal and prelens tear film, form, and stability, and lens wettability, were assessed in vivo by a battery of 21 tests including wide-field diff use light biomicroscopy. Scanning electron micrographs were taken of the kns surfaces and the area covered with deposits measured with a digitizer. The results demonstrated that tear film, lens wet&&y, and deposit resistance did not vary significantly with fluorine level or cleaning. This indicates that maximum efficacy had been reached for these clinical performance criteria and was not concentration dependent for fluorine level.5 greater than 20%.
New techniques are proven in this thesis which allow the visual examination of the tear film on t... more New techniques are proven in this thesis which allow the visual examination of the tear film on the cornea and on different types of contact lenses. The techniques are as follows: 1. A high magnification technique of photography using the bio-microscope and crossed polarised light, allows the measurement of tear film layer thickness's and on the surface of rigid contact lenses and 'in-vivo receding contact angle'. 2. A low magnification technique of photography allows the recording and the analysis of the superficial layers of the tear film over a wide area of the eye and contact lens surface. 3. A clinical instrument has been designed for the routine clinical observation of the tear film. It permits the visual measurement of the tear film break-up time (BUT) without the use of fluorescein. 4. A unique technique of in-vivo photography of the mucous coverage of the corneal epithelial surface and contact lens surfaces is presented. Such techniques improve the understanding...
Advances in Experimental Medicine and Biology
1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine ex... more 1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine examination of the marginal dry eye contact lens patient. Guillon JP. Scope Research Limited, Institute of Optometry, London, England, United Kingdom. ...
Advances in experimental medicine and biology, 1998
1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine ex... more 1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine examination of the marginal dry eye contact lens patient. Guillon JP. Scope Research Limited, Institute of Optometry, London, England, United Kingdom. ...
Advances in experimental medicine and biology, 2002
Journal français d'ophtalmologie, 1999
Advances in Experimental Medicine and Biology, 1998
Ophthalmology, 2003
To measure the thickness of the precorneal lipid layer and the stability of the precorneal tear f... more To measure the thickness of the precorneal lipid layer and the stability of the precorneal tear film in neonates and infants in the first 6 postnatal months. Prospective, observational case series. One hundred ninety-eight neonates and infants in the newborn nursery. The Keeler Tearscope Plus (Keeler Instruments Inc., Broomall, PA) was used to evaluate lipid layer thickness by interference fringe biomicroscopy and directly to measure noninvasive tear breakup time (NIBUT). The thickness was classified from level 1 (open meshwork-very thin) to level 9 (colored fringe pattern-very thick). Noninvasive tear breakup time in seconds and classification level of lipid layer thickness. The mean lipid layer classification for all newborns was 8.3 +/- 0.9, with no significant difference between genders. The thickest classifications (levels 8 and 9) were found in 83.3% of all infants. At 3 and 6 postnatal months, all infants studied had a lipid layer classification of 9. Mean NIBUT was 32.5 +/- 5.2 seconds (range, 17.6-48.5 seconds) and was not significantly different whether stratified by race, postconceptional age, or birthweight. However, although NIBUT was longer in males at birth (35.1 +/- 4.2 seconds versus 29.4 +/- 4.5 seconds; P < 0.001), it was equal in both genders at 3 and 6 postnatal months. In the first 6 postnatal months, the lipid layer of the tear film is much thicker than in adults. The NIBUT in newborns is prolonged compared with adult values. This thick lipid layer in infants provides stability that may help prevent the thin aqueous layer from evaporating.
Journal of The British Contact Lens Association, 1994
Optometry and Vision Science, 1994
Optometry and Vision Science, 1994
Techniques in Ophthalmology, 2003
Journal of The British Contact Lens Association, 1995
International Contact Lens Clinic, 1993
... Performance Stability of Disposable Contact Lenses Michel Guillon, PhD, FBCO, FAAO, Jean-Pier... more ... Performance Stability of Disposable Contact Lenses Michel Guillon, PhD, FBCO, FAAO, Jean-Pierre Guillon, PhD, FBCO, and Dipti Shah, BSc ... Visual acuity was recorded with Regan Contrast Sen-sitivity letter charts.6 These are logMAR progression charts that have already ...
Journal of The British Contact Lens Association, 1989
Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 24-26, 1989, Author... more Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 24-26, 1989, Authors:Michel Guillon, PhD, FBCO; Jean-Pierre Guillon, BSc, FBCO; Veronica Mapstone; Susan Dwyer. Journal Home, Register or Login: Password: Auto-Login [Reminder]. ...
Journal of The British Contact Lens Association, 1982
Journal of The British Contact Lens Association, 1989
Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 44-45, 1989, Author... more Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 44-45, 1989, Authors:Jean-Pierre Guillon, BSc, FBCO; Michel Guillon, PhD, FBCO; Susan Dwyer; Veronica Mapstone. Journal Home, Register or Login: Password: Auto-Login [Reminder]. ...
International Contact Lens Clinic, 1991
This study investigated the effect of variations in fluorine concentration, varied in a fixed rel... more This study investigated the effect of variations in fluorine concentration, varied in a fixed relationship with the hydrophilic monomers 20, 30, and 40% by weight, of fluorosilicone acrylate RGP polymers on tear film, lens wettability, and deposit resistance. Precomeal and prelens tear film, form, and stability, and lens wettability, were assessed in vivo by a battery of 21 tests including wide-field diff use light biomicroscopy. Scanning electron micrographs were taken of the kns surfaces and the area covered with deposits measured with a digitizer. The results demonstrated that tear film, lens wet&&y, and deposit resistance did not vary significantly with fluorine level or cleaning. This indicates that maximum efficacy had been reached for these clinical performance criteria and was not concentration dependent for fluorine level.5 greater than 20%.
New techniques are proven in this thesis which allow the visual examination of the tear film on t... more New techniques are proven in this thesis which allow the visual examination of the tear film on the cornea and on different types of contact lenses. The techniques are as follows: 1. A high magnification technique of photography using the bio-microscope and crossed polarised light, allows the measurement of tear film layer thickness's and on the surface of rigid contact lenses and 'in-vivo receding contact angle'. 2. A low magnification technique of photography allows the recording and the analysis of the superficial layers of the tear film over a wide area of the eye and contact lens surface. 3. A clinical instrument has been designed for the routine clinical observation of the tear film. It permits the visual measurement of the tear film break-up time (BUT) without the use of fluorescein. 4. A unique technique of in-vivo photography of the mucous coverage of the corneal epithelial surface and contact lens surfaces is presented. Such techniques improve the understanding...
Advances in Experimental Medicine and Biology
1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine ex... more 1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine examination of the marginal dry eye contact lens patient. Guillon JP. Scope Research Limited, Institute of Optometry, London, England, United Kingdom. ...
Advances in experimental medicine and biology, 1998
1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine ex... more 1. Adv Exp Med Biol. 1998;438:859-67. Use of the Tearscope Plus and attachments in the routine examination of the marginal dry eye contact lens patient. Guillon JP. Scope Research Limited, Institute of Optometry, London, England, United Kingdom. ...
Advances in experimental medicine and biology, 2002
Journal français d'ophtalmologie, 1999
Advances in Experimental Medicine and Biology, 1998
Ophthalmology, 2003
To measure the thickness of the precorneal lipid layer and the stability of the precorneal tear f... more To measure the thickness of the precorneal lipid layer and the stability of the precorneal tear film in neonates and infants in the first 6 postnatal months. Prospective, observational case series. One hundred ninety-eight neonates and infants in the newborn nursery. The Keeler Tearscope Plus (Keeler Instruments Inc., Broomall, PA) was used to evaluate lipid layer thickness by interference fringe biomicroscopy and directly to measure noninvasive tear breakup time (NIBUT). The thickness was classified from level 1 (open meshwork-very thin) to level 9 (colored fringe pattern-very thick). Noninvasive tear breakup time in seconds and classification level of lipid layer thickness. The mean lipid layer classification for all newborns was 8.3 +/- 0.9, with no significant difference between genders. The thickest classifications (levels 8 and 9) were found in 83.3% of all infants. At 3 and 6 postnatal months, all infants studied had a lipid layer classification of 9. Mean NIBUT was 32.5 +/- 5.2 seconds (range, 17.6-48.5 seconds) and was not significantly different whether stratified by race, postconceptional age, or birthweight. However, although NIBUT was longer in males at birth (35.1 +/- 4.2 seconds versus 29.4 +/- 4.5 seconds; P < 0.001), it was equal in both genders at 3 and 6 postnatal months. In the first 6 postnatal months, the lipid layer of the tear film is much thicker than in adults. The NIBUT in newborns is prolonged compared with adult values. This thick lipid layer in infants provides stability that may help prevent the thin aqueous layer from evaporating.
Journal of The British Contact Lens Association, 1994
Optometry and Vision Science, 1994
Optometry and Vision Science, 1994
Techniques in Ophthalmology, 2003
Journal of The British Contact Lens Association, 1995
International Contact Lens Clinic, 1993
... Performance Stability of Disposable Contact Lenses Michel Guillon, PhD, FBCO, FAAO, Jean-Pier... more ... Performance Stability of Disposable Contact Lenses Michel Guillon, PhD, FBCO, FAAO, Jean-Pierre Guillon, PhD, FBCO, and Dipti Shah, BSc ... Visual acuity was recorded with Regan Contrast Sen-sitivity letter charts.6 These are logMAR progression charts that have already ...
Journal of The British Contact Lens Association, 1989
Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 24-26, 1989, Author... more Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 24-26, 1989, Authors:Michel Guillon, PhD, FBCO; Jean-Pierre Guillon, BSc, FBCO; Veronica Mapstone; Susan Dwyer. Journal Home, Register or Login: Password: Auto-Login [Reminder]. ...
Journal of The British Contact Lens Association, 1982
Journal of The British Contact Lens Association, 1989
Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 44-45, 1989, Author... more Journal of The British Contact Lens Association, Volume 12, Issue null, Pages 44-45, 1989, Authors:Jean-Pierre Guillon, BSc, FBCO; Michel Guillon, PhD, FBCO; Susan Dwyer; Veronica Mapstone. Journal Home, Register or Login: Password: Auto-Login [Reminder]. ...