Jeeten Prasad - Academia.edu (original) (raw)

Papers by Jeeten Prasad

Research paper thumbnail of A causal model for software cost estimating error

Software cost estimating is an important concern for software managers and other software profess... more Software cost estimating is an important concern for software managers and other software professionals. The hypothesized model in this research suggests that an organization's use of an estimate influences its estimating practices which influence both the basis of the estimating process and the accuracy of the estimate. The model also suggests that the estimating basis directly influences the accuracy of the estimate. A study of business information systems managers and professionals at 112 different organizations using causal analysis with Equations Modeling System (EQS) refined the model. The refined model shows that no managerial practice in this study discourages the use of intuition, guessing, and personal memory in cost estimating. Although user commitment and accountability appear to foster algorithm-based estimating, such an algorithmic basis does not portend greater accuracy. Only one managerial practice-the use of the estimate in performance evaluations of software managers and professionals-presages greater accuracy. By implication, the research suggests somewhat ironically that the most effective approach to improve estimating accuracy may be to make estimators, developers, and managers more accountable for the estimate even though it may be impossible to direct them explicitly on how to produce a more accurate one.

Research paper thumbnail of Information systems software cost estimating: a current assessment

A study of information systems managers and other information systems professionals at 112 differ... more A study of information systems managers and other information systems professionals at 112 different organizations confirmed that information systems software cost estimating is an important concern. Subjects reported the completion of only one of every four systems development projects within their estimates. According to them, the major cause of inaccurate estimates was changes in user requirements. Organizations using sophisticated cost estimating software packages were less successful at preventing large cost overruns than organizations not using them. However, the use of the estimator as system developer, the careful monitoring of systems development projects, and the inclusion in performance evaluations of success in meeting estimates were associated with more accurate cost estimating.

Research paper thumbnail of Effect of Bromocryptine on hormones and milk secretion in Murrah buffaloes ( Bubalus bubalis)

animal, 2010

An experiment was carried out on 10 advance pregnant Murrah buffaloes to determine the role of ho... more An experiment was carried out on 10 advance pregnant Murrah buffaloes to determine the role of hormones in milk secretion around parturition. Experimental animals were administered with a single injection of bromocryptine, @ 100 μg/kg BW, for 5 days before expected calving, whereas control group buffaloes were injected with placebo injections. Blood samples collected before parturition (−5,−4,−3,−2,−1 days), on day of parturition (day-0) and on day 1, 2, 3, 4, 5, 10 and 15post partumwere analyzed for growth hormone (GH), insulin like growth factor-I (IGF-I) and prolactin (PRL) by radioimmunassay methods. Milk samples were collected daily for 5 days and on day 10 and 15 after parturition. Milk fat, protein, lactose, citric acid, non-esterified fatty acids (NEFAs) and somatic cell counts (SCCs) were determined in milk samples. Bromocryptine treatment significantly (P< 0.01) decreasedpre partumPRL and increased GH levels (P< 0.01) on day of parturition in experimental buffaloes w...

Research paper thumbnail of Optimizing pattern fill for planarity and parasitic capacitance

… , 2004. ASMC'04. …, 2003

Keywords Design for manufacturability (DFM), early manufacturing involvement, improved planarity,... more Keywords Design for manufacturability (DFM), early manufacturing involvement, improved planarity, improved photolithogra-phy margin. ... INTRODUCTION In integrated circuit manufacturing with multi-level inter-connect, it is important to have a planar surface preceding the next ...

Research paper thumbnail of vi Spotlights

Research paper thumbnail of Heat and osmotic stress responses of probiotic Lactobacillus rhamnosus HN001 (DR20) in relation to viability after drying

Applied and environmental …, 2003

The viability of lactic acid bacteria in frozen, freeze-dried, and air-dried forms is of signific... more The viability of lactic acid bacteria in frozen, freeze-dried, and air-dried forms is of significant commercial interest to both the dairy and food industries. In this study we observed that when prestressed with either heat (50°C) or salt (0.6 M NaCl), Lactobacillus rhamnosus HN001 ( ...

Research paper thumbnail of Industry institute interaction for capability building in engineering education in India a study on the Indian Information Technology companies

… and Information Technology (ICICT), 2009

... Report of the High Level Strategic Group. [8] Can academia bail out Industry from manpower sh... more ... Report of the High Level Strategic Group. [8] Can academia bail out Industry from manpower shortage?– Sangeetha Chengappa. ... [11] How the Disciple became the Guru– Vivek Wadhwa, Una Kim de Vitton, Gary Gereffi– K Ewing Marion Kauffman Foundation. ...

Research paper thumbnail of Safety assessment of potential probiotic lactic acid bacterial strains Lactobacillus rhamnosus HN001, Lb. acidophilus HN017, and Bifidobacterium lactis HN019 in BALB/c mice

International Journal of Food Microbiology, 2000

The general safety of immune-enhancing lactic acid bacteria (LAB) strains Lactobacillus rhamnosus... more The general safety of immune-enhancing lactic acid bacteria (LAB) strains Lactobacillus rhamnosus HN001 (DR20), Lb. acidophilus HN017, and Bifidobacterium lactis HN019 (DR10) was investigated in a feeding trial. Groups of BALB/c mice were orally administered test LAB strains or the commercial reference strain Lb. acidophilus LA-1 at 2.5 x 10(9), 5 x 10(10) or 2.5 x 10(12) colony forming units (CFU)/kg body weight/day for 4 weeks. Throughout this time, their feed intake, water intake, and live body weight were monitored. At the end of the 4 week observation period, samples of blood, liver, spleen, kidney, mesenteric lymph nodes, and gut tissues (ileum, caecum, and colon) were collected to determine: haematological parameters (red blood cell and platelet counts, haemoglobin concentration, mean corpuscular volume, mean corpuscular haemoglobin, and mean corpuscular haemoglobin concentration); differential leukocyte counts; blood biochemistry (plasma total protein, albumin, cholesterol, ...

Research paper thumbnail of Agroforestry as a Strategy for Livelihood Security in the Rainfed Areas: Experience and Expectations

In book: Agroforestry Systems in India: Livelihood Security& Ecosystem Services, Edition: Advances in Agroforestry 10, Chapter: 5,, 2014

Agroforestry in rainfed areas increases livelihood security through simultaneous production of fo... more Agroforestry in rainfed areas increases livelihood security through simultaneous production of food, fodder, and firewood, and an increase in total productivity per unit area of land. Management of trees in conjunction with crops in rainfed areas minimizes the risk associated with stress period through diversified components and through efficient utilization of limited natural resources. The major objective of agroforestry in rainfed areas is gainful utilization of off-season precipitation, income stabilization, soil and water conservation, insurance against weather aberrations and mitigation of climate change. In India, agroforestry practices in rainfed agriculture have been used to manage scattered trees on farm lands, trees on farm bunds, wood lots as block plantations, trees on range lands, and vegetative live hedges for ecological, social, and economic functions. To enhance rural livelihood security among the dryland farmers, several improved agroforestry systems, commercial plantations and biofuels and bioenergy systems came into being for adoption. Agroforestry plantation-based success stories reveal livelihood security of small, marginal, and landless farmers. Steps to promote basic and promotional agroforestry research in dryland agriculture and appropriate policy responses with extension outreach may potentially deliver better results in rainfed agriculture. Rainfed agroforestry for livelihood security reflects the positive way in utilization of rainfed area resources.

Research paper thumbnail of Target-matching test problem for multiobjective topology optimization using genetic algorithms

Structural and Multidisciplinary Optimization, 2007

This paper describes the multiobjective topology optimization of continuum structures solved as a... more This paper describes the multiobjective topology optimization of continuum structures solved as a discrete optimization problem using a multiobjective genetic algorithm (GA) with proficient constraint handling. Crucial to the effectiveness of the methodology is the use of a morphological geometry representation that defines valid structural geometries that are inherently free from checkerboard patterns, disconnected segments, or poor connectivity. A graph-

Research paper thumbnail of Finite p-groups with isomorphic subgroups

Can. J. Math, 1973

Canadian Mathematical Society. www.cms.math.ca. Go to CMS home page, Canadian Mathematical Societ... more Canadian Mathematical Society. www.cms.math.ca. Go to CMS home page, Canadian Mathematical Society. Social Media, |, Site map, |, CMS store. Membership: individual: benefits; categories; annual rates; join; renew; update your info; website accounts. institutional: benefits; categories & rates; join; renew. corporate; terms & conditions; membership lists: search; combined membership list (CML); individuals - alphabetic; individuals - geographic; individuals ...

Research paper thumbnail of Choosing Management Information Systems as a Major: Understanding the smiFactors for MIS

Given declining management information systems (MIS) enrollments at our university, we seek to un... more Given declining management information systems (MIS) enrollments at our university, we seek to understand our students' selection of a major. Prior studies have found that students choose a major based on a number of factors, with subject matter interest consistently being most important. We contribute to the literature by developing a deeper understanding of what is meant by subject matter interest, which we refer to as smiFactors, for MIS as a major and career. Based on a qualitative analysis of open-ended survey questions completed by undergraduate business students, we confirm a number of smiFactors for MIS gleaned from recent studies and identify three new ones. We also relate our findings to broad categories of vocational interests. Of the newly identified smiFactors, one-linking business and technology-is unique to MIS, whereas the other two-practical application of course work and daily variety-apply to MIS as well as other majors and careers. Our findings provide a more complete foundation for helping students make an informed choice of MIS as a major. We use our findings and an extension of the Theory of Planned Behavior (TPB) to identify four types of intervention for increasing MIS enrollments.

Research paper thumbnail of Cardiac autonomic function in acutely nitric oxide deficient hypertensive rats: role of the sympathetic nervous system and oxidative stress

We evaluated the role of the sympathetic nervous system and oxidative stress in hemodynamic and a... more We evaluated the role of the sympathetic nervous system and oxidative stress in hemodynamic and autonomic control after acute inhibition of the synthesis of nitric oxide, using intravenous (i.v.) injection of 30 mg·kg–1 NG-nitro-l-arginine methyl ester (L-NAME) in adult Wistar rats. Baroreflex sensitivity (BRS) and heart rate variability (HRV) were measured as indices of cardiac autonomic control, before and after L-NAME treatment in rats with intact autonomic innervation, and in rats with chemical sympathectomy by 6-hydroxydopamine. Serum malondialdehyde (MDA) was measured as a marker of oxidative stress. In control rats, L-NAME treatment resulted in a significant rise in blood pressure, augmentation of BRS, and enhanced serum MDA. HRV showed an attenuation of total spectral power and high frequency spectral power, along with a rise of the low to high frequency ratio (LF:HF). Administration of L-NAME produced a pressor response even in sympathectomised rats, but augmented BRS was not observed, and the high frequency spectral power showed an increase, in addition to a significant decline of LF:HF and serum MDA. We therefore conclude that even though pressor response was unaffected, reversal of cardiac autonomic responses and decline in oxidative stress following sympathectomy in L-NAME-treated rats reflects a significant role for sympathetic innervation in acute L-NAME-induced hypertension.

Research paper thumbnail of Improvement in gas stripping capability by installation of turbo molecular pump system in the terminal of 15 UD pelletron

Research paper thumbnail of Colorimetric determination of molybdenum by the reaction with thiocyanate

Fresenius' Zeitschrift f�r Analytische Chemie, 1966

Research paper thumbnail of Behavioral Protection by Mentha spicata Linn. against Radiation-induced Conditioned Taste Aversion:A Comparative Study With a Radioprotective Calcium Channel Blocking Drug

Research paper thumbnail of Whole body protection against lethal ionizing radiation in mice by REC-2001: a semi-purified fraction of Podophyllum hexandrum

The current study has concentrated on assessment of the radioprotective potential of REC-2001, a ... more The current study has concentrated on assessment of the radioprotective potential of REC-2001, a semi-purified fraction of rhizomes of Podophyllum hexandrum, in Swiss albino Strain 'A' mice exposed to 10 Gy whole-body gamma radiation. Animals were treated with 10 and 15 mg/kg b wt (i.p.) of REC-2001 1 h prior to exposure to a lethal dose of g-radiation (10 Gy) and observed upto 30 days. For analysis of maximum tolerable dose (MTD), LD 50 and acute toxic dose, different concentrations of the extract were administered to animals and their mortality and morbidity status was observed upto 72 h and one week, respectively. Dose reduction factor (DRF) was determined by exposing REC-2001 pre-treated mice to supra-lethal doses of g-radiation. Endogenous spleen colony forming units (CFU), DNA strand breaks in thymocytes (alkaline halo assay) and lipid degradation was studied to understand the mechanism of radioprotection. A single dose of REC-2001 (10 and 15 mg/kg b wt i.p.) exhibited 490% survival in the pre-treated irradiated group versus no survival in radiation control group. Single doses of upto 75 mg/kg b wt (i.p.) did not cause any mortality (MTD) in mice. REC-2001, a dose of 90 mg/kg b wt, resulted in 50% mortality (LD 50), while the LD 100 was 115 mg/kg b wt REC-2001 exhibited a DRF of 1.62. CFU counts in the REC-2001 treated group were found significantly high (5.33/spleen) as compared to controls. Exposure of thymocytes to 10 Gy radiation resulted in increased halo diameter (4573 mm) in comparison to untreated controls (871 mm). REC-2001 administration (500 mg/ ml) decreased the halo diameter to 1572 mm. Radiation-induced lipid degradation was also inhibited by REC-2001. The present study has revealed that REC-2001 is a promising radioprotective fraction that can be effectively used against lethal doses of g-radiation after further investigations in higher animal models.

Research paper thumbnail of Zingiber officinale Rosc. modulates gamma radiation-induced conditioned taste aversion

The aim of the present study was to investigate the neurobehavioral protective efficacy of a hydr... more The aim of the present study was to investigate the neurobehavioral protective efficacy of a hydroalcoholic extract of ginger (Zingiber officinale Rosc.) in mitigating gamma radiation-induced conditioned taste aversion in Sprague-Dawley rats. Administration of Zingiber extract 1 h before 2-Gy gamma irradiation was effective in blocking the saccharin avoidance response for 5 post-treatment observational days, both in a dose- and time-dependent manner, with 200 mg/kg b.w. i.p. being the most effective dose. Highest saccharin intake in all the groups was observed on the fifth post-treatment day. The potential of ginger extract to inhibit lipid peroxidation induced by radiation (2 Gy) and ascorbate-ion stress in brain homogenate and its ability to scavenge highly reactive superoxide anions were evaluated. The 1000-microg/ml and 2000-microg/ml concentration of ginger extract showed the highest efficiency in scavenging free radicals and in inhibiting lipid peroxidation. The lipid peroxidation and superoxide-anion scavenging ability of the extract further supports its radioprotective properties. The results clearly establish the neurobehavioral efficacy of ginger extract and the antioxidant properties appear to be a contributing factor in its overall ability to modulate radiation-induced conditioned taste aversion. Ginger extract has tremendous potential for clinical applications in mitigation of radiation-induced emesis in humans.

Research paper thumbnail of Zingiber officinale exhibits behavioral radioprotection against radiation-induced CTA in a gender-specific manner

At the organismic level, exposure to radiation can produce taste aversion (CTA) learning and emes... more At the organismic level, exposure to radiation can produce taste aversion (CTA) learning and emesis, which have been proposed as behavioral endpoints that are mediated by harmful effects of radiations on peripheral systems, primarily the gastrointestinal system. Thus, the aim of the present investigation was to study the gastroprotective action of hydroalcoholic extract of zingiber rhizome (Zingiber officinale Rosc.) against radiation-induced conditioned taste aversion (CTA) in both male and female species of animals, for testing its potential as a behavioral radioprotector. Administration of zingiber extract 1 h before 2-Gy gamma-radiation was significantly effective in blocking the saccharin avoidance response, with 200 and 250 mg/kg b.wt. i.p., being the most effective doses for male and female rats, respectively. A comparison of the efficacy of zingiber extract with two antiemetic drugs, ondansteron and dexamethasone, revealed that the extract rendered comparable protection against radiation-induced CTA. Our experiments also confirmed the existence of sex dichotomy (i.e., the sex of animal greatly influenced response towards radiation exposure) in relation to behavioral responses (CTA) or differential metabolism. The observed gender variations were hypothesized to be a result of hormonal fluctuations and differences in pharmacological parameters in male and female rats. To correlate the mechanism of action, the free-radical-scavenging potential of zingiber extract to scavenge hydroxyl ion and nitric oxide was also tested, in cell-free system and a concentration of 1000 microg/ml, was found to be the most potent, which has been proposed as one the many activities assisting in its overall ability to modulate radiation-induced taste aversion. The results demonstrate that Z. officinale possesses antioxidant, radioprotective and neuromodulatory properties that can be effectively utilized for behavioral radioprotection and for efficiently mitigating radiation-induced CTA in both males and females species.

Research paper thumbnail of Fabrication of High Pressure Hydrogen Adsorption/Desorption Unit���Adsorption Study on Flame Synthesized Carbon Nanofibers

ABSTRACT An in-house custom made high pressure adsorption/desorption unit has been designed and f... more ABSTRACT An in-house custom made high pressure adsorption/desorption unit has been designed and fabricated to study reversible hydrogen (H2) intake capacity, hysteresis, kinetics, plateau pressure of various nanomaterials, zeolites and metallic compounds, in the pressure range of 1 ≤ P ≤ 150 atm. The unit has been used to estimate H2 intake capacity of carbon nanofibers prepared by flame synthesis in the absence of catalyst. H2 adsorption studies have been carried out in the pressure range of 25–100 atm at 297 K. The maximum H2 intake capacity has been observed to be 3.7 wt% at 100 atm.

Research paper thumbnail of A causal model for software cost estimating error

Software cost estimating is an important concern for software managers and other software profess... more Software cost estimating is an important concern for software managers and other software professionals. The hypothesized model in this research suggests that an organization's use of an estimate influences its estimating practices which influence both the basis of the estimating process and the accuracy of the estimate. The model also suggests that the estimating basis directly influences the accuracy of the estimate. A study of business information systems managers and professionals at 112 different organizations using causal analysis with Equations Modeling System (EQS) refined the model. The refined model shows that no managerial practice in this study discourages the use of intuition, guessing, and personal memory in cost estimating. Although user commitment and accountability appear to foster algorithm-based estimating, such an algorithmic basis does not portend greater accuracy. Only one managerial practice-the use of the estimate in performance evaluations of software managers and professionals-presages greater accuracy. By implication, the research suggests somewhat ironically that the most effective approach to improve estimating accuracy may be to make estimators, developers, and managers more accountable for the estimate even though it may be impossible to direct them explicitly on how to produce a more accurate one.

Research paper thumbnail of Information systems software cost estimating: a current assessment

A study of information systems managers and other information systems professionals at 112 differ... more A study of information systems managers and other information systems professionals at 112 different organizations confirmed that information systems software cost estimating is an important concern. Subjects reported the completion of only one of every four systems development projects within their estimates. According to them, the major cause of inaccurate estimates was changes in user requirements. Organizations using sophisticated cost estimating software packages were less successful at preventing large cost overruns than organizations not using them. However, the use of the estimator as system developer, the careful monitoring of systems development projects, and the inclusion in performance evaluations of success in meeting estimates were associated with more accurate cost estimating.

Research paper thumbnail of Effect of Bromocryptine on hormones and milk secretion in Murrah buffaloes ( Bubalus bubalis)

animal, 2010

An experiment was carried out on 10 advance pregnant Murrah buffaloes to determine the role of ho... more An experiment was carried out on 10 advance pregnant Murrah buffaloes to determine the role of hormones in milk secretion around parturition. Experimental animals were administered with a single injection of bromocryptine, @ 100 μg/kg BW, for 5 days before expected calving, whereas control group buffaloes were injected with placebo injections. Blood samples collected before parturition (−5,−4,−3,−2,−1 days), on day of parturition (day-0) and on day 1, 2, 3, 4, 5, 10 and 15post partumwere analyzed for growth hormone (GH), insulin like growth factor-I (IGF-I) and prolactin (PRL) by radioimmunassay methods. Milk samples were collected daily for 5 days and on day 10 and 15 after parturition. Milk fat, protein, lactose, citric acid, non-esterified fatty acids (NEFAs) and somatic cell counts (SCCs) were determined in milk samples. Bromocryptine treatment significantly (P< 0.01) decreasedpre partumPRL and increased GH levels (P< 0.01) on day of parturition in experimental buffaloes w...

Research paper thumbnail of Optimizing pattern fill for planarity and parasitic capacitance

… , 2004. ASMC'04. …, 2003

Keywords Design for manufacturability (DFM), early manufacturing involvement, improved planarity,... more Keywords Design for manufacturability (DFM), early manufacturing involvement, improved planarity, improved photolithogra-phy margin. ... INTRODUCTION In integrated circuit manufacturing with multi-level inter-connect, it is important to have a planar surface preceding the next ...

Research paper thumbnail of vi Spotlights

Research paper thumbnail of Heat and osmotic stress responses of probiotic Lactobacillus rhamnosus HN001 (DR20) in relation to viability after drying

Applied and environmental …, 2003

The viability of lactic acid bacteria in frozen, freeze-dried, and air-dried forms is of signific... more The viability of lactic acid bacteria in frozen, freeze-dried, and air-dried forms is of significant commercial interest to both the dairy and food industries. In this study we observed that when prestressed with either heat (50°C) or salt (0.6 M NaCl), Lactobacillus rhamnosus HN001 ( ...

Research paper thumbnail of Industry institute interaction for capability building in engineering education in India a study on the Indian Information Technology companies

… and Information Technology (ICICT), 2009

... Report of the High Level Strategic Group. [8] Can academia bail out Industry from manpower sh... more ... Report of the High Level Strategic Group. [8] Can academia bail out Industry from manpower shortage?– Sangeetha Chengappa. ... [11] How the Disciple became the Guru– Vivek Wadhwa, Una Kim de Vitton, Gary Gereffi– K Ewing Marion Kauffman Foundation. ...

Research paper thumbnail of Safety assessment of potential probiotic lactic acid bacterial strains Lactobacillus rhamnosus HN001, Lb. acidophilus HN017, and Bifidobacterium lactis HN019 in BALB/c mice

International Journal of Food Microbiology, 2000

The general safety of immune-enhancing lactic acid bacteria (LAB) strains Lactobacillus rhamnosus... more The general safety of immune-enhancing lactic acid bacteria (LAB) strains Lactobacillus rhamnosus HN001 (DR20), Lb. acidophilus HN017, and Bifidobacterium lactis HN019 (DR10) was investigated in a feeding trial. Groups of BALB/c mice were orally administered test LAB strains or the commercial reference strain Lb. acidophilus LA-1 at 2.5 x 10(9), 5 x 10(10) or 2.5 x 10(12) colony forming units (CFU)/kg body weight/day for 4 weeks. Throughout this time, their feed intake, water intake, and live body weight were monitored. At the end of the 4 week observation period, samples of blood, liver, spleen, kidney, mesenteric lymph nodes, and gut tissues (ileum, caecum, and colon) were collected to determine: haematological parameters (red blood cell and platelet counts, haemoglobin concentration, mean corpuscular volume, mean corpuscular haemoglobin, and mean corpuscular haemoglobin concentration); differential leukocyte counts; blood biochemistry (plasma total protein, albumin, cholesterol, ...

Research paper thumbnail of Agroforestry as a Strategy for Livelihood Security in the Rainfed Areas: Experience and Expectations

In book: Agroforestry Systems in India: Livelihood Security& Ecosystem Services, Edition: Advances in Agroforestry 10, Chapter: 5,, 2014

Agroforestry in rainfed areas increases livelihood security through simultaneous production of fo... more Agroforestry in rainfed areas increases livelihood security through simultaneous production of food, fodder, and firewood, and an increase in total productivity per unit area of land. Management of trees in conjunction with crops in rainfed areas minimizes the risk associated with stress period through diversified components and through efficient utilization of limited natural resources. The major objective of agroforestry in rainfed areas is gainful utilization of off-season precipitation, income stabilization, soil and water conservation, insurance against weather aberrations and mitigation of climate change. In India, agroforestry practices in rainfed agriculture have been used to manage scattered trees on farm lands, trees on farm bunds, wood lots as block plantations, trees on range lands, and vegetative live hedges for ecological, social, and economic functions. To enhance rural livelihood security among the dryland farmers, several improved agroforestry systems, commercial plantations and biofuels and bioenergy systems came into being for adoption. Agroforestry plantation-based success stories reveal livelihood security of small, marginal, and landless farmers. Steps to promote basic and promotional agroforestry research in dryland agriculture and appropriate policy responses with extension outreach may potentially deliver better results in rainfed agriculture. Rainfed agroforestry for livelihood security reflects the positive way in utilization of rainfed area resources.

Research paper thumbnail of Target-matching test problem for multiobjective topology optimization using genetic algorithms

Structural and Multidisciplinary Optimization, 2007

This paper describes the multiobjective topology optimization of continuum structures solved as a... more This paper describes the multiobjective topology optimization of continuum structures solved as a discrete optimization problem using a multiobjective genetic algorithm (GA) with proficient constraint handling. Crucial to the effectiveness of the methodology is the use of a morphological geometry representation that defines valid structural geometries that are inherently free from checkerboard patterns, disconnected segments, or poor connectivity. A graph-

Research paper thumbnail of Finite p-groups with isomorphic subgroups

Can. J. Math, 1973

Canadian Mathematical Society. www.cms.math.ca. Go to CMS home page, Canadian Mathematical Societ... more Canadian Mathematical Society. www.cms.math.ca. Go to CMS home page, Canadian Mathematical Society. Social Media, |, Site map, |, CMS store. Membership: individual: benefits; categories; annual rates; join; renew; update your info; website accounts. institutional: benefits; categories & rates; join; renew. corporate; terms & conditions; membership lists: search; combined membership list (CML); individuals - alphabetic; individuals - geographic; individuals ...

Research paper thumbnail of Choosing Management Information Systems as a Major: Understanding the smiFactors for MIS

Given declining management information systems (MIS) enrollments at our university, we seek to un... more Given declining management information systems (MIS) enrollments at our university, we seek to understand our students' selection of a major. Prior studies have found that students choose a major based on a number of factors, with subject matter interest consistently being most important. We contribute to the literature by developing a deeper understanding of what is meant by subject matter interest, which we refer to as smiFactors, for MIS as a major and career. Based on a qualitative analysis of open-ended survey questions completed by undergraduate business students, we confirm a number of smiFactors for MIS gleaned from recent studies and identify three new ones. We also relate our findings to broad categories of vocational interests. Of the newly identified smiFactors, one-linking business and technology-is unique to MIS, whereas the other two-practical application of course work and daily variety-apply to MIS as well as other majors and careers. Our findings provide a more complete foundation for helping students make an informed choice of MIS as a major. We use our findings and an extension of the Theory of Planned Behavior (TPB) to identify four types of intervention for increasing MIS enrollments.

Research paper thumbnail of Cardiac autonomic function in acutely nitric oxide deficient hypertensive rats: role of the sympathetic nervous system and oxidative stress

We evaluated the role of the sympathetic nervous system and oxidative stress in hemodynamic and a... more We evaluated the role of the sympathetic nervous system and oxidative stress in hemodynamic and autonomic control after acute inhibition of the synthesis of nitric oxide, using intravenous (i.v.) injection of 30 mg·kg–1 NG-nitro-l-arginine methyl ester (L-NAME) in adult Wistar rats. Baroreflex sensitivity (BRS) and heart rate variability (HRV) were measured as indices of cardiac autonomic control, before and after L-NAME treatment in rats with intact autonomic innervation, and in rats with chemical sympathectomy by 6-hydroxydopamine. Serum malondialdehyde (MDA) was measured as a marker of oxidative stress. In control rats, L-NAME treatment resulted in a significant rise in blood pressure, augmentation of BRS, and enhanced serum MDA. HRV showed an attenuation of total spectral power and high frequency spectral power, along with a rise of the low to high frequency ratio (LF:HF). Administration of L-NAME produced a pressor response even in sympathectomised rats, but augmented BRS was not observed, and the high frequency spectral power showed an increase, in addition to a significant decline of LF:HF and serum MDA. We therefore conclude that even though pressor response was unaffected, reversal of cardiac autonomic responses and decline in oxidative stress following sympathectomy in L-NAME-treated rats reflects a significant role for sympathetic innervation in acute L-NAME-induced hypertension.

Research paper thumbnail of Improvement in gas stripping capability by installation of turbo molecular pump system in the terminal of 15 UD pelletron

Research paper thumbnail of Colorimetric determination of molybdenum by the reaction with thiocyanate

Fresenius' Zeitschrift f�r Analytische Chemie, 1966

Research paper thumbnail of Behavioral Protection by Mentha spicata Linn. against Radiation-induced Conditioned Taste Aversion:A Comparative Study With a Radioprotective Calcium Channel Blocking Drug

Research paper thumbnail of Whole body protection against lethal ionizing radiation in mice by REC-2001: a semi-purified fraction of Podophyllum hexandrum

The current study has concentrated on assessment of the radioprotective potential of REC-2001, a ... more The current study has concentrated on assessment of the radioprotective potential of REC-2001, a semi-purified fraction of rhizomes of Podophyllum hexandrum, in Swiss albino Strain 'A' mice exposed to 10 Gy whole-body gamma radiation. Animals were treated with 10 and 15 mg/kg b wt (i.p.) of REC-2001 1 h prior to exposure to a lethal dose of g-radiation (10 Gy) and observed upto 30 days. For analysis of maximum tolerable dose (MTD), LD 50 and acute toxic dose, different concentrations of the extract were administered to animals and their mortality and morbidity status was observed upto 72 h and one week, respectively. Dose reduction factor (DRF) was determined by exposing REC-2001 pre-treated mice to supra-lethal doses of g-radiation. Endogenous spleen colony forming units (CFU), DNA strand breaks in thymocytes (alkaline halo assay) and lipid degradation was studied to understand the mechanism of radioprotection. A single dose of REC-2001 (10 and 15 mg/kg b wt i.p.) exhibited 490% survival in the pre-treated irradiated group versus no survival in radiation control group. Single doses of upto 75 mg/kg b wt (i.p.) did not cause any mortality (MTD) in mice. REC-2001, a dose of 90 mg/kg b wt, resulted in 50% mortality (LD 50), while the LD 100 was 115 mg/kg b wt REC-2001 exhibited a DRF of 1.62. CFU counts in the REC-2001 treated group were found significantly high (5.33/spleen) as compared to controls. Exposure of thymocytes to 10 Gy radiation resulted in increased halo diameter (4573 mm) in comparison to untreated controls (871 mm). REC-2001 administration (500 mg/ ml) decreased the halo diameter to 1572 mm. Radiation-induced lipid degradation was also inhibited by REC-2001. The present study has revealed that REC-2001 is a promising radioprotective fraction that can be effectively used against lethal doses of g-radiation after further investigations in higher animal models.

Research paper thumbnail of Zingiber officinale Rosc. modulates gamma radiation-induced conditioned taste aversion

The aim of the present study was to investigate the neurobehavioral protective efficacy of a hydr... more The aim of the present study was to investigate the neurobehavioral protective efficacy of a hydroalcoholic extract of ginger (Zingiber officinale Rosc.) in mitigating gamma radiation-induced conditioned taste aversion in Sprague-Dawley rats. Administration of Zingiber extract 1 h before 2-Gy gamma irradiation was effective in blocking the saccharin avoidance response for 5 post-treatment observational days, both in a dose- and time-dependent manner, with 200 mg/kg b.w. i.p. being the most effective dose. Highest saccharin intake in all the groups was observed on the fifth post-treatment day. The potential of ginger extract to inhibit lipid peroxidation induced by radiation (2 Gy) and ascorbate-ion stress in brain homogenate and its ability to scavenge highly reactive superoxide anions were evaluated. The 1000-microg/ml and 2000-microg/ml concentration of ginger extract showed the highest efficiency in scavenging free radicals and in inhibiting lipid peroxidation. The lipid peroxidation and superoxide-anion scavenging ability of the extract further supports its radioprotective properties. The results clearly establish the neurobehavioral efficacy of ginger extract and the antioxidant properties appear to be a contributing factor in its overall ability to modulate radiation-induced conditioned taste aversion. Ginger extract has tremendous potential for clinical applications in mitigation of radiation-induced emesis in humans.

Research paper thumbnail of Zingiber officinale exhibits behavioral radioprotection against radiation-induced CTA in a gender-specific manner

At the organismic level, exposure to radiation can produce taste aversion (CTA) learning and emes... more At the organismic level, exposure to radiation can produce taste aversion (CTA) learning and emesis, which have been proposed as behavioral endpoints that are mediated by harmful effects of radiations on peripheral systems, primarily the gastrointestinal system. Thus, the aim of the present investigation was to study the gastroprotective action of hydroalcoholic extract of zingiber rhizome (Zingiber officinale Rosc.) against radiation-induced conditioned taste aversion (CTA) in both male and female species of animals, for testing its potential as a behavioral radioprotector. Administration of zingiber extract 1 h before 2-Gy gamma-radiation was significantly effective in blocking the saccharin avoidance response, with 200 and 250 mg/kg b.wt. i.p., being the most effective doses for male and female rats, respectively. A comparison of the efficacy of zingiber extract with two antiemetic drugs, ondansteron and dexamethasone, revealed that the extract rendered comparable protection against radiation-induced CTA. Our experiments also confirmed the existence of sex dichotomy (i.e., the sex of animal greatly influenced response towards radiation exposure) in relation to behavioral responses (CTA) or differential metabolism. The observed gender variations were hypothesized to be a result of hormonal fluctuations and differences in pharmacological parameters in male and female rats. To correlate the mechanism of action, the free-radical-scavenging potential of zingiber extract to scavenge hydroxyl ion and nitric oxide was also tested, in cell-free system and a concentration of 1000 microg/ml, was found to be the most potent, which has been proposed as one the many activities assisting in its overall ability to modulate radiation-induced taste aversion. The results demonstrate that Z. officinale possesses antioxidant, radioprotective and neuromodulatory properties that can be effectively utilized for behavioral radioprotection and for efficiently mitigating radiation-induced CTA in both males and females species.

Research paper thumbnail of Fabrication of High Pressure Hydrogen Adsorption/Desorption Unit���Adsorption Study on Flame Synthesized Carbon Nanofibers

ABSTRACT An in-house custom made high pressure adsorption/desorption unit has been designed and f... more ABSTRACT An in-house custom made high pressure adsorption/desorption unit has been designed and fabricated to study reversible hydrogen (H2) intake capacity, hysteresis, kinetics, plateau pressure of various nanomaterials, zeolites and metallic compounds, in the pressure range of 1 ≤ P ≤ 150 atm. The unit has been used to estimate H2 intake capacity of carbon nanofibers prepared by flame synthesis in the absence of catalyst. H2 adsorption studies have been carried out in the pressure range of 25–100 atm at 297 K. The maximum H2 intake capacity has been observed to be 3.7 wt% at 100 atm.