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Jeremy Metz

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Papers by Jeremy Metz

Research paper thumbnail of Robust Entanglement through Macroscopic Quantum Jumps

Physical Review Letters, 2006

We propose an entanglement generation scheme that requires neither the coherent evolution of a qu... more We propose an entanglement generation scheme that requires neither the coherent evolution of a quantum system nor the detection of single photons. Instead, the desired state is heralded by a {\em macroscopic} quantum jump. Macroscopic quantum jumps manifest themselves as a random telegraph signal with long intervals of intense fluorescence (light periods) interrupted by the complete absence of photons (dark periods). Here we show that a system of two atoms trapped inside an optical cavity can be designed such that a dark period prepares the atoms in a maximally entangled ground state. Achieving fidelities above 0.9 is possible even when the single-atom cooperativity parameter C is as low as 10 and when using a photon detector with an efficiency as low as eta = 0.2.

Research paper thumbnail of An automated method for tracking punctate objects in live cell imaging data

Research paper thumbnail of Quantum Computing With Macroscopic Heralding

Research paper thumbnail of Quantum Computing with Macroscopic Fluorescence Signals

Research paper thumbnail of Atomic cluster state build-up with macroscopic heralding

Physical Review A, 2007

We describe a measurement-based state preparation scheme for the efficient build up of cluster st... more We describe a measurement-based state preparation scheme for the efficient build up of cluster states in atom-cavity systems. As in a recent proposal for the generation of maximally entangled atom pairs [Metz et al., Phys. Rev. Lett. 97, 040503 (2006)], we use an electron shelving technique to avoid the necessity for the detection of single photons. Instead, the successful fusion of smaller into larger clusters is heralded by an easy-to-detect macroscopic fluorescence signal. High fidelities are achieved even in the vicinity of the bad cavity limit and are essentially independent of the concrete size of the system parameters.

Research paper thumbnail of Synergy between multiple microtubule-generating pathways confers robustness to centrosome-driven mitotic spindle formation

Research paper thumbnail of Robust Entanglement through Macroscopic Quantum Jumps

Physical Review Letters, 2006

We propose an entanglement generation scheme that requires neither the coherent evolution of a qu... more We propose an entanglement generation scheme that requires neither the coherent evolution of a quantum system nor the detection of single photons. Instead, the desired state is heralded by a {\em macroscopic} quantum jump. Macroscopic quantum jumps manifest themselves as a random telegraph signal with long intervals of intense fluorescence (light periods) interrupted by the complete absence of photons (dark periods). Here we show that a system of two atoms trapped inside an optical cavity can be designed such that a dark period prepares the atoms in a maximally entangled ground state. Achieving fidelities above 0.9 is possible even when the single-atom cooperativity parameter C is as low as 10 and when using a photon detector with an efficiency as low as eta = 0.2.

Research paper thumbnail of A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes

Genes & development, Jan 15, 2009

Research paper thumbnail of Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis

Cell cycle (Georgetown, Tex.), Jan 15, 2012

Fidgetin is a member of the AAA protein superfamily with important roles in mammalian development... more Fidgetin is a member of the AAA protein superfamily with important roles in mammalian development. Here we show that human Fidgetin is a potent microtubule severing and depolymerizing the enzyme used to regulate mitotic spindle architecture, dynamics and anaphase A. In vitro, recombinant human Fidgetin severs taxol-stabilized microtubules along their length and promotes depolymerization, primarily from their minus-ends. In cells, human Fidgetin targets to centrosomes, and its depletion with siRNA significantly reduces the velocity of poleward tubulin flux and anaphase A chromatid-to-pole motion. In addition, the loss of Fidgetin induces a microtubule-dependent enlargement of mitotic centrosomes and an increase in the number and length of astral microtubules. Based on these data, we propose that human Fidgetin actively suppresses microtubule growth from and attachment to centrosomes.

Research paper thumbnail of A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes

Research paper thumbnail of Towards quantum computing with single atoms and optical cavities on atom chips

Research paper thumbnail of Effect of frequency-mismatched photons in quantum-information processing

Research paper thumbnail of Macroscopic quantum jumps and entangled-state preparation

Research paper thumbnail of Robust entanglement through macroscopic quantum jumps

Physical review letters, 2006

Research paper thumbnail of Atomic cluster state build-up with macroscopic heralding

Research paper thumbnail of Robust Entanglement through Macroscopic Quantum Jumps

Physical Review Letters, 2006

We propose an entanglement generation scheme that requires neither the coherent evolution of a qu... more We propose an entanglement generation scheme that requires neither the coherent evolution of a quantum system nor the detection of single photons. Instead, the desired state is heralded by a {\em macroscopic} quantum jump. Macroscopic quantum jumps manifest themselves as a random telegraph signal with long intervals of intense fluorescence (light periods) interrupted by the complete absence of photons (dark periods). Here we show that a system of two atoms trapped inside an optical cavity can be designed such that a dark period prepares the atoms in a maximally entangled ground state. Achieving fidelities above 0.9 is possible even when the single-atom cooperativity parameter C is as low as 10 and when using a photon detector with an efficiency as low as eta = 0.2.

Research paper thumbnail of An automated method for tracking punctate objects in live cell imaging data

Research paper thumbnail of Quantum Computing With Macroscopic Heralding

Research paper thumbnail of Quantum Computing with Macroscopic Fluorescence Signals

Research paper thumbnail of Atomic cluster state build-up with macroscopic heralding

Physical Review A, 2007

We describe a measurement-based state preparation scheme for the efficient build up of cluster st... more We describe a measurement-based state preparation scheme for the efficient build up of cluster states in atom-cavity systems. As in a recent proposal for the generation of maximally entangled atom pairs [Metz et al., Phys. Rev. Lett. 97, 040503 (2006)], we use an electron shelving technique to avoid the necessity for the detection of single photons. Instead, the successful fusion of smaller into larger clusters is heralded by an easy-to-detect macroscopic fluorescence signal. High fidelities are achieved even in the vicinity of the bad cavity limit and are essentially independent of the concrete size of the system parameters.

Research paper thumbnail of Synergy between multiple microtubule-generating pathways confers robustness to centrosome-driven mitotic spindle formation

Research paper thumbnail of Robust Entanglement through Macroscopic Quantum Jumps

Physical Review Letters, 2006

We propose an entanglement generation scheme that requires neither the coherent evolution of a qu... more We propose an entanglement generation scheme that requires neither the coherent evolution of a quantum system nor the detection of single photons. Instead, the desired state is heralded by a {\em macroscopic} quantum jump. Macroscopic quantum jumps manifest themselves as a random telegraph signal with long intervals of intense fluorescence (light periods) interrupted by the complete absence of photons (dark periods). Here we show that a system of two atoms trapped inside an optical cavity can be designed such that a dark period prepares the atoms in a maximally entangled ground state. Achieving fidelities above 0.9 is possible even when the single-atom cooperativity parameter C is as low as 10 and when using a photon detector with an efficiency as low as eta = 0.2.

Research paper thumbnail of A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes

Genes & development, Jan 15, 2009

Research paper thumbnail of Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis

Cell cycle (Georgetown, Tex.), Jan 15, 2012

Fidgetin is a member of the AAA protein superfamily with important roles in mammalian development... more Fidgetin is a member of the AAA protein superfamily with important roles in mammalian development. Here we show that human Fidgetin is a potent microtubule severing and depolymerizing the enzyme used to regulate mitotic spindle architecture, dynamics and anaphase A. In vitro, recombinant human Fidgetin severs taxol-stabilized microtubules along their length and promotes depolymerization, primarily from their minus-ends. In cells, human Fidgetin targets to centrosomes, and its depletion with siRNA significantly reduces the velocity of poleward tubulin flux and anaphase A chromatid-to-pole motion. In addition, the loss of Fidgetin induces a microtubule-dependent enlargement of mitotic centrosomes and an increase in the number and length of astral microtubules. Based on these data, we propose that human Fidgetin actively suppresses microtubule growth from and attachment to centrosomes.

Research paper thumbnail of A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes

Research paper thumbnail of Towards quantum computing with single atoms and optical cavities on atom chips

Research paper thumbnail of Effect of frequency-mismatched photons in quantum-information processing

Research paper thumbnail of Macroscopic quantum jumps and entangled-state preparation

Research paper thumbnail of Robust entanglement through macroscopic quantum jumps

Physical review letters, 2006

Research paper thumbnail of Atomic cluster state build-up with macroscopic heralding

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