Jessica Holiday - Academia.edu (original) (raw)

Papers by Jessica Holiday

Modern Language Review, 2006

These files are supplementary data for the submitted manuscript "Co-occurrence of Cell Lines... more These files are supplementary data for the submitted manuscript "Co-occurrence of Cell Lines, Basal Media and Supplementation in the Biomedical Research Literature". The file 'cellDictionary.csv' contains a dictionary of the cell lines used to annotate our corpus, with a column for the cell line and their synonyms. This is adapted from Cellosaurus, Version 29. The file 'mediaDictionary.csv' contains a dictionary of curated basal medias and their synonyms.

This dataset contains three key pieces of data: 1. journal-list-issn.csv : contains a list of jou... more This dataset contains three key pieces of data: 1. journal-list-issn.csv : contains a list of journal names and ISSNs that our corpus was limited to. 2. mediaQueriesMendeley.csv: contains a list of 39 distinct queries we used to search the corpus, all referencing one of 27 unique basal medias. 3. The folder 'Open Access sentences' includes 4 partitioned parquet files that together comprise a dataframe of 15,424 sentences that appeared in one of the journals and had a hit for one of the basal medias. The dataframe is structured as 'sentence', 'pii', 'year'.

Robotic Labs, in which experiments are carried out entirely by robots, have the potential to prov... more Robotic Labs, in which experiments are carried out entirely by robots, have the potential to provide a reproducible and transparent foundation for performing basic biomedical laboratory experiments. In this article, we investigate whether these labs are applicable in current experimental practice. We do this by text mining 1628 papers for occurrences of methods that are supported by commercial robotic labs. We find that 62% of the papers have at least one of these methods. This and our other results provide indications that robotic labs can serve as the foundation for performing many lab-based experiments.

This is a collection of data used for the article "Indicators for the use of Robotic Labs in... more This is a collection of data used for the article "Indicators for the use of Robotic Labs in Basic Biomedical Research". The primary result files are: -metamapMethods.csv -sodaMethods.csv These were generated by running descriptive statistics of annotating the papers listed in articles_piis_dois.csv with the Medical Subject Headings 2015 vocabulary.

PeerJ, Nov 8, 2017

Robotic labs, in which experiments are carried out entirely by robots, have the potential to prov... more Robotic labs, in which experiments are carried out entirely by robots, have the potential to provide a reproducible and transparent foundation for performing basic biomedical laboratory experiments. In this article, we investigate whether these labs could be applicable in current experimental practice. We do this by text mining 1,628 papers for occurrences of methods that are supported by commercial robotic labs. Using two different concept recognition tools, we find that 86%-89% of the papers have at least one of these methods. This and our other results provide indications that robotic labs can serve as the foundation for performing many lab-based experiments.

Blood, Nov 5, 2021

Background: Transition from pediatric to adult care has been a recent focus of sickle cell progra... more Background: Transition from pediatric to adult care has been a recent focus of sickle cell programs across the country due to patients with sickle cell disease (SCD) to living longer. 1 Transition programs for other chronic conditions focus largely on patient knowledge of the disease, treatments, and appointment compliance but for patients with SCD, social determinants of health (SDOH) must also be considered when guiding patients toward adult care. 2 Historically, lack of acknowledgement of the importance of relationships and trust building when addressing SDOH has led to barriers in patient responsiveness. 3 To facilitate this aspect of transition, our recently hired Community Health Worker (CHW) developed a Community Health Transitional Questionnaire (CHTQ) and conducted a Quality Improvement (QI) project to address SDOH in a patient-centered manner during transition to adult care visits at the clinic. Aims: Refine the CHTQ by gathering the "voice of the customer" to provide a more patient-centered approach to transition to adult care for patients with SCD. Complete the CHTQ with 70% of transition-aged (12-25 years) patients by 7/1/21. Methods: The CHTQ consists of 32 questions about SDOH in 8 categories (Food, Housing, Money/Finances, Transportation, Education/Work, Family and Other Support, Stress Prior to/After COVID, and Sleep). Thirty pediatric sickle cell patients were identified as being within the established transitional age group. A series of Plan-Do-Study-Act (PDSA) cycles were used to refine the CHTQ. Through patient/caregiver feedback, small increments of change were used to establish a CHTQ that would improve patient care and be accepted by the patients/caregivers. PDSA #1: During regularly scheduled appointments, two patients and their caregivers met with the CHW who described the purpose of the CHTQ and then asked the patient to privately complete the CHTQ. PDSA #2: Because of feedback received from PDSA #1, the CHW allowed the next two patients to have caregivers present while answering the CHTQ, but explained that ideally the patient should be able to answer the CHTQ without input from their caregiver before transition to an adult environment. PDSA #3: Because of the feedback received from PDSA #2, the CHW accompanied the clinic RN to the exam room and worked the CHTQ into the nursing check-in questions in an informal manner making the questions seem more routine. Results: After 3 PDSA cycles, 17 additional patients/caregivers completed the CHTQ without issues or concerns. A total of 22/30 (73%) CHTQs met the goal of completion by 7/1/21. One additional CHTQ has been completed since. Using the information from the CHTQ, the team has been able to better address individualized SDOH for each patient. For example, one area of concern identified was transportation with 9/23 (39%) patients expressing concerns getting to &amp; from appointments and/or school/work. Transportation needs were then discussed with the clinic social worker who is now working with those patients, giving them tools to arrange transportation. Conclusion For SCD patients, it appears imperative that a relationship be established prior to inquires about SDOH. Using an informal patient-centered approach with the CHTQ was more likely to gain patient trust and allowed the CHW to obtain information needed to assist the patient with SDOH issues. Once SDOH issues were identified through the CHTQ, the CHW was able to find patient-driven, individualized resources addressing those concerns. References DeBaun, M.R. &amp; Telfair, J. (2012). Transition and Sickle Cell Disease. PEDIATRICS, 130(5), 926-935 https://doi.org/10.1542/peds.2011-3049 Andermann, A. (2016). Taking action on the social determinants of health in clinical practice: a framework for health professionals. Canadian Medical Association Journal, 188(17-18), E474-E483. https://doi.org/10.1503/cmaj.160177 Cheney, C., Pecci, A., &amp; Porter, S (2020, May). Social Determinants of Health: Lead or Partner. HealthLeaders. https://www.healthleadersmedia.com/clinical-care/social-determinants-health-lead-or-partner-0 Disclosures No relevant conflicts of interest to declare.

Results from the OPPERA study provided evidence that risk factors such as neck muscle tension, pr... more Results from the OPPERA study provided evidence that risk factors such as neck muscle tension, prolonged jaw opening, and female gender increase the likelihood of developing temporomandibular joint disorders (TMJD), which are prevalent, debilitating orofacial pain conditions. Peripheral and central sensitization, which mediate a lowering of the stimulus required for pain signaling, are implicated in the underlying pathology of chronic TMJD. The goal of my study was to investigate cellular changes in the expression of proteins associated with the development of central sensitization. Female Sprague-Dawley rats were injected with complete Freund's adjuvant in the upper trapezius muscles to promote trigeminal sensitization. After 8 days, animals were subjected to near maximal jaw opening for 20 minutes, and spinal cord tissues were collected at several time points until day 28 post jaw opening. Changes in proteins associated with neuronal and glial cell activation were investigated in the medullary dorsal horn using immunohistochemistry. Somewhat surprisingly, consistently increased protein expression was not observed in second-order nociceptive neurons, astrocytes, or microglia in the dorsal horn. Thus, my results are suggestive that this novel model for inducing chronic TMJD pathology is mechanistically different from other reported inflammatory-induced TMJD models. Based on my results, I propose that this model that involves pain signaling in response to prolonged jaw opening in sensitized animals involves dysfunction of descending inhibitory signaling and likely involves changes in the expression of cytokines and miRNAs.

Lecture Notes in Computer Science, 2018

To define salient rhetorical elements in scholarly text, we have earlier defined a set of Discour... more To define salient rhetorical elements in scholarly text, we have earlier defined a set of Discourse Segment Types: semantically defined spans of discourse at the level of a clause with a single rhetorical purpose, such as Hypothesis, Method or Result. In this paper, we use machine learning methods to predict these Discourse Segment Types in a corpus of biomedical research papers. The initial experiment used features related to verb type and form, obtaining F-scores ranging from 0.41-0.65. To improve our results, we explored a variety of methods for balancing classes, before applying classification algorithms. We also performed an ablation study and stepwise approach for feature selection. Through these feature selection processes, we were able to reduce our 37 features to the 7 most informative ones, while maintaining F1 scores in the range of 0.63-0.65. Next, we performed an experiment with a reduced set of target classes. Using only verb tense features, logistic regression, a decision tree classifier and a random forest classifier, we predicted that a segment type was either a Result/Method or a Fact/Implication, with F1 scores above 0.8. Interestingly, findings from this machine learning approach are in line with a reader experiment, which found a correlation between verb tense and a biomedical reader's interpretation of discourse segment type. This suggests that experimental and concept-centric discourse in biology texts can be distinguished by humans or machines, using verb tense as a key feature.

Journal of surgical case reports, 2023

Solitary fibrous tumor (SFT) are rare pleura neoplasms often localized to middle or inferior hemi... more Solitary fibrous tumor (SFT) are rare pleura neoplasms often localized to middle or inferior hemithorax. A middle-aged woman presents to the emergency department following a motor vehicle accident, the computed tomography scan revealed a giant tumor occupying the entire left pleural cavity with a complete collapse of the left lung and substantial right deviation of heart and mediastinum. Using preoperative arterial coiling followed by a double-level thoracotomy we successfully resected the giant tumor. The SFT weighed ∼10 lbs. At 2-month follow-up visit patient reports mild discomfort during strenuous movement/heavy lifting but denies any shortness of breath.

Journal of The American College of Surgeons, Oct 17, 2022

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Washington Quarterly, Jan 2, 2021

Artificial intelligence (AI) is developing at a rapid pace—both the technology itself and its app... more Artificial intelligence (AI) is developing at a rapid pace—both the technology itself and its applications. It is becoming unavoidable in both the civilian and military domains and will soon impact numerous areas of civilian and military life. In July 2020, for example, countries such as Colombia and Russia applied facial recognition technology, a form of artificial intelligence, to combat the coronavirus by detecting whether someone was not wearing a mask or had a high temperature through the use of thermal cameras and sounding an alarm. That same month, Open AI, a California company leading in AI technology, released the software GPT-3, a text generator that can mimic human creativity to write convincing essays, emails, or tweets. Global AI-generated revenue is projected to climb from US$643.7 million in 2016 to US$36.8 billion in 2025, a factor of almost 60 times greater. Both the United States and its NATO allies have placed new emphasis on understanding the civilian and military applications of technological

Journal of The Audio Engineering Society, Mar 1, 1984

L'egaliseur automatique fonctionne a la fois comme l'egaliseur traditionnel et comme un s... more L'egaliseur automatique fonctionne a la fois comme l'egaliseur traditionnel et comme un suppresseur (boucle reaction) d'oscillations

Acknowledgements Jessica Cox: Introduction: Blurring Boundaries: The Fiction of M.E. Braddon New ... more Acknowledgements Jessica Cox: Introduction: Blurring Boundaries: The Fiction of M.E. Braddon New Perspectives on Lady Audley's Secret Tabitha Sparks: To the Mad-House Born: The Ethics of Exteriority in Lady Audley's Secret Nancy Knowles and Katherine Hall: Imperial Attitudes in Lady Audley's Secret Michelle Lin: "To Go Boldly Where No Woman Has Gone Before": Alicia Audley and the New Woman Grace Wetzel: Homelessness in the Home: Invention, Instability and Insanity in the Domestic Spaces of M.E. Braddon and L.M. Alcott Beyond Lady Audley's Secret Andrew Mangham: "Drink It Up Dear It Will Do You Good": Crime, Toxicology, and The Trail of the Serpent Anne-Marie Beller : Sensational Bildung? Infantilization and Female Maturation in Braddon's 1860s Novels Juliette Atkinson: To "Serve God and Mammon": Braddon and Literary Transgression Joanne Knowles: The French Connection: Gender, Morals and National Culture in Braddon's Novels Tamara S. Wagner: Re-Plotting Inheritance: The Triangulation of Legacies and Affinities in The Fatal Three Laurence Talairach-Vielmas: "If I Read Her Right": Textual Secrets in Thou Art the Man (1894) Kate Mattacks: Sensationalism on Trial: Courtroom Drama and the Image of Respectability in His Darling Sin Carla E. Coleman: "The Stage! Oh, Flora, the Very Idea Frightens Me!": Representations of Professional Theatre in Rupert Godwin and A Lost Eden Bibliography Notes on Contributors Index

International Journal on Child Maltreatment: Research, Policy and Practice

Proceedings of the 15th International Workshop on Semantic Evaluation (SemEval-2021)

We describe MeasEval, a SemEval task of extracting counts, measurements, and related context from... more We describe MeasEval, a SemEval task of extracting counts, measurements, and related context from scientific documents, which is of significant importance to the creation of Knowledge Graphs that distill information from the scientific literature. This is a new task in 2021, for which over 75 submissions from 25 participants were received. We expect the data developed for this task and the findings reported to be valuable to the scientific knowledge extraction, metrology, and automated knowledge base construction communities.

Journal of the American Veterinary Medical Association