Jhonas Geraldo - Academia.edu (original) (raw)
Papers by Jhonas Geraldo
Biotechnology and Applied Biochemistry, 2014
Although adsorption is an essential step in the enzymatic hydrolysis of lignocellulosic materials... more Although adsorption is an essential step in the enzymatic hydrolysis of lignocellulosic materials, literature reports controversial results in relation to the adsorption of the cellulolitic enzymes on different biomasses/pretreatments, which makes difficult the description of this phenomenon in hydrolysis mathematical models. In this work, the adsorption of these enzymes on Avicel and sugarcane bagasse pretreated by the hydrothermal bagasse (HB) and organosolv bagasse (OB) methods was evaluated. The results have shown no significant adsorption of β-glucosidase on Avicel or HB. Increasing solids concentration from 5% (w/v) to 10% (w/v) had no impact on the adsorption of cellulase on the different biomasses if stirring rates were high enough (>100 rpm for Avicel and >150 rpm for HB and OB). Adsorption equilibrium time was low for Avicel (10 Min) when compared with the lignocellulosic materials (120 Min). Adsorption isotherms determined at 4 and 50 °C have shown that for Avicel there was a decrease in the maximum adsorption capacity (Emax ) with the temperature increase, whereas for HB increasing temperature increased Emax . Also, Emax increased with the content of lignin in the material. Adsorption studies of cellulase on lignin left after enzymatic digestion of HB show lower but significant adsorption capacity (Emax = 11.92 ± 0.76 mg/g).
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Relatase, pela primeira vez no Brasil, a ocorrência de mastite gangrenosa caprina atípica causad... more Relatase, pela primeira vez no Brasil, a ocorrência de mastite gangrenosa caprina atípica causada pela coinfecção por Staphylococcus aureus, Clostridium perfringens e Escherichia coli em uma cabra da raça Boer, na segunda semana de lactação. Descrevem-se os achados clínicos, os procedimentos de diagnóstico microbiológico e a conduta terapêutica.
Portal hypertensive gastropathy is considered a serinol-induced gastric injury, related to an ina... more Portal hypertensive gastropathy is considered a serinol-induced gastric injury, related to an inability to ous complication observed in patients with cirrhosis mount a defensive gastric hyperemic response to lumiand portal hypertension. 1,2 The pathophysiology of the nal irritants, and associated with an impaired reactivity profound alterations in mucosal defense against injury of the gastric microcirculation to nitric oxide (NO)/cyclic observed in portal hypertension have demonstrated guanosine monophosphate (cGMP)-dependent vasodilathat the increased susceptibility of the gastric mucosa tors. Whether this hyporesponsiveness is in some way to injury was intimately related to vascular abnormalirelated to depressed prostaglandin synthesis by the ties in the gastric microcirculation. 3-5 stomach of cirrhotic rats is not clear. The aims of this The gastric hyperemic response to irritants is a critistudy were to evaluate the role of NO and prostaglandins cal component of mucosal defense. It is responsible for in the regulation of the gastric microcirculation under resting conditions and in response to administration of the buffering of back-diffused acid and dilution and sodium nitroprusside, as well as to investigate the mechremoval of noxious agents that enter the mucosa. 6 An anisms of the hyporesponsiveness of the gastric microincreased susceptibility of the gastric mucosa to ethacirculation to nitrovasodilators. Cirrhosis was induced nol-induced injury in cirrhotic rats is associated with in rats by bile duct ligation, and controls had sham-opera defective hyperemic response. 3 Vasodilators such as ation. N G-nitro-L-arginine-methyl-ester (L-NAME) and nitric oxide and prostaglandins are believed to be the indomethacin administration produced a greater reducmajor mediators involved in the control of the gastric tion in gastric blood flow in cirrhotic rats than controls. microcirculation and mucosal integrity. 6-9 Exposure of Indomethacin pretreatment almost completely abolished the responsiveness to sodium nitroprusside the gastric mucosa to an irritant results in activation (NaNP) in cirrhotic rats, while not affecting controls. of sensory afferent nerves, leading to the release of Long-term administration of misoprostol to cirrhotic calcitonin gene-related peptide and, in turn, to dilation rats restored to normal the responsiveness to NaNP, of submucosal arterioles through an NO-dependent whereas long-term administration of aspirin to healthy pathway. 10,11 Cirrhotic rats have a normal anatomic rats resulted in a hyporesponsiveness of the gastric midistribution of the afferent nerves; however, applicacrocirculation to NaNP similar to that seen in cirrhotic tion of acid, 20% ethanol, or capsaicin to the mucosa rats. We conclude that there are interactions between was found not to cause an increase in gastric blood NO and prostaglandins in regulating gastric blood flow in both healthy and cirrhotic rats. The hyporespon-flow. In addition, the gastric blood flow response siveness of the gastric microcirculation of cirrhotic rats to exogenous NO/cyclic guanosine monophosphate to a nitrovasodilator may occur as a consequence of pro-(cGMP)-dependent vasodilators is impaired in cirrhotic longed depression of gastric prostaglandin synthesis. rats. 12 Conversely, cirrhotic rats exhibited an increased (HEPATOLOGY 1996;23:123-129.) responsiveness to cyclic adenosine monophosphate (cAMP)-dependent vasodilators, including prostaglandins. 12,13 Gastric prostaglandin E 2 (PGE 2) synthesis is significantly depressed in cirrhotic rats and chronic ad-Abbreviations: cGMP, cyclic guanosine monophosphate; cAMP, cyclic adenosine monophosphate; PGE2, prostaglandin E2; PBS, phosphate-buffered sa-ministration of a PGE 1 analog, misoprostol, resulted in line; L-NAME, N G-nitro-L-arginine-methyl-ester; D-NAME, N G-nitro-D-argia normalization of gastric resistance to ethanol-innine-methyl-ester; BP, blood pressure; NaNP, sodium nitroprusside.
Latin American Music Review, 2007
... 234 : José Geraldo já encarnava naquele período de meados da década de 1950 o papel do grande... more ... 234 : José Geraldo já encarnava naquele período de meados da década de 1950 o papel do grande historiador da música popular-Almirante: "A mais alta patente" Seu nome de batismo era Henrique Foréis Domingues (1908-Engenho Novo, Rio de Janeiro-1980) e nasceu ...
Biotechnology and Applied Biochemistry, 2014
Although adsorption is an essential step in the enzymatic hydrolysis of lignocellulosic materials... more Although adsorption is an essential step in the enzymatic hydrolysis of lignocellulosic materials, literature reports controversial results in relation to the adsorption of the cellulolitic enzymes on different biomasses/pretreatments, which makes difficult the description of this phenomenon in hydrolysis mathematical models. In this work, the adsorption of these enzymes on Avicel and sugarcane bagasse pretreated by the hydrothermal bagasse (HB) and organosolv bagasse (OB) methods was evaluated. The results have shown no significant adsorption of β-glucosidase on Avicel or HB. Increasing solids concentration from 5% (w/v) to 10% (w/v) had no impact on the adsorption of cellulase on the different biomasses if stirring rates were high enough (>100 rpm for Avicel and >150 rpm for HB and OB). Adsorption equilibrium time was low for Avicel (10 Min) when compared with the lignocellulosic materials (120 Min). Adsorption isotherms determined at 4 and 50 °C have shown that for Avicel there was a decrease in the maximum adsorption capacity (Emax ) with the temperature increase, whereas for HB increasing temperature increased Emax . Also, Emax increased with the content of lignin in the material. Adsorption studies of cellulase on lignin left after enzymatic digestion of HB show lower but significant adsorption capacity (Emax = 11.92 ± 0.76 mg/g).
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Relatase, pela primeira vez no Brasil, a ocorrência de mastite gangrenosa caprina atípica causad... more Relatase, pela primeira vez no Brasil, a ocorrência de mastite gangrenosa caprina atípica causada pela coinfecção por Staphylococcus aureus, Clostridium perfringens e Escherichia coli em uma cabra da raça Boer, na segunda semana de lactação. Descrevem-se os achados clínicos, os procedimentos de diagnóstico microbiológico e a conduta terapêutica.
Portal hypertensive gastropathy is considered a serinol-induced gastric injury, related to an ina... more Portal hypertensive gastropathy is considered a serinol-induced gastric injury, related to an inability to ous complication observed in patients with cirrhosis mount a defensive gastric hyperemic response to lumiand portal hypertension. 1,2 The pathophysiology of the nal irritants, and associated with an impaired reactivity profound alterations in mucosal defense against injury of the gastric microcirculation to nitric oxide (NO)/cyclic observed in portal hypertension have demonstrated guanosine monophosphate (cGMP)-dependent vasodilathat the increased susceptibility of the gastric mucosa tors. Whether this hyporesponsiveness is in some way to injury was intimately related to vascular abnormalirelated to depressed prostaglandin synthesis by the ties in the gastric microcirculation. 3-5 stomach of cirrhotic rats is not clear. The aims of this The gastric hyperemic response to irritants is a critistudy were to evaluate the role of NO and prostaglandins cal component of mucosal defense. It is responsible for in the regulation of the gastric microcirculation under resting conditions and in response to administration of the buffering of back-diffused acid and dilution and sodium nitroprusside, as well as to investigate the mechremoval of noxious agents that enter the mucosa. 6 An anisms of the hyporesponsiveness of the gastric microincreased susceptibility of the gastric mucosa to ethacirculation to nitrovasodilators. Cirrhosis was induced nol-induced injury in cirrhotic rats is associated with in rats by bile duct ligation, and controls had sham-opera defective hyperemic response. 3 Vasodilators such as ation. N G-nitro-L-arginine-methyl-ester (L-NAME) and nitric oxide and prostaglandins are believed to be the indomethacin administration produced a greater reducmajor mediators involved in the control of the gastric tion in gastric blood flow in cirrhotic rats than controls. microcirculation and mucosal integrity. 6-9 Exposure of Indomethacin pretreatment almost completely abolished the responsiveness to sodium nitroprusside the gastric mucosa to an irritant results in activation (NaNP) in cirrhotic rats, while not affecting controls. of sensory afferent nerves, leading to the release of Long-term administration of misoprostol to cirrhotic calcitonin gene-related peptide and, in turn, to dilation rats restored to normal the responsiveness to NaNP, of submucosal arterioles through an NO-dependent whereas long-term administration of aspirin to healthy pathway. 10,11 Cirrhotic rats have a normal anatomic rats resulted in a hyporesponsiveness of the gastric midistribution of the afferent nerves; however, applicacrocirculation to NaNP similar to that seen in cirrhotic tion of acid, 20% ethanol, or capsaicin to the mucosa rats. We conclude that there are interactions between was found not to cause an increase in gastric blood NO and prostaglandins in regulating gastric blood flow in both healthy and cirrhotic rats. The hyporespon-flow. In addition, the gastric blood flow response siveness of the gastric microcirculation of cirrhotic rats to exogenous NO/cyclic guanosine monophosphate to a nitrovasodilator may occur as a consequence of pro-(cGMP)-dependent vasodilators is impaired in cirrhotic longed depression of gastric prostaglandin synthesis. rats. 12 Conversely, cirrhotic rats exhibited an increased (HEPATOLOGY 1996;23:123-129.) responsiveness to cyclic adenosine monophosphate (cAMP)-dependent vasodilators, including prostaglandins. 12,13 Gastric prostaglandin E 2 (PGE 2) synthesis is significantly depressed in cirrhotic rats and chronic ad-Abbreviations: cGMP, cyclic guanosine monophosphate; cAMP, cyclic adenosine monophosphate; PGE2, prostaglandin E2; PBS, phosphate-buffered sa-ministration of a PGE 1 analog, misoprostol, resulted in line; L-NAME, N G-nitro-L-arginine-methyl-ester; D-NAME, N G-nitro-D-argia normalization of gastric resistance to ethanol-innine-methyl-ester; BP, blood pressure; NaNP, sodium nitroprusside.
Latin American Music Review, 2007
... 234 : José Geraldo já encarnava naquele período de meados da década de 1950 o papel do grande... more ... 234 : José Geraldo já encarnava naquele período de meados da década de 1950 o papel do grande historiador da música popular-Almirante: "A mais alta patente" Seu nome de batismo era Henrique Foréis Domingues (1908-Engenho Novo, Rio de Janeiro-1980) e nasceu ...