Jodi Visnu - Academia.edu (original) (raw)

Papers by Jodi Visnu

Research paper thumbnail of Metabolomic Assay, Computational Screening, and Pharmacological Evaluation of Caulerpa racemosa as an Anti-obesity With Anti-aging by Altering Lipid Profile and Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α Levels

Frontiers in Nutrition

Obesity is associated with an accelerated aging process, which prevents healthy aging. Both obesi... more Obesity is associated with an accelerated aging process, which prevents healthy aging. Both obesity and aging were manifested in the peroxisome proliferator-activated receptor-γ coactivator α (PGC-1α) level. These studies fulfill the scientific gap in assembled pharmacological activity assay of Caulerpa racemosa done in a previous preclinical trial. Six major compounds from sea grape (C. racemosa) extract were evaluated using an in silico approach against human pancreatic lipase, a-glucosidase, and a-amylase to predict prospective anti-obesity candidates. The lipase inhibitory activity of the extract reached 90.30 ± 0.40%, 1.75% lower than orlistat. The a-amylase inhibitory assay of the extract was 84.07 ± 5.28%, while the inhibitory activity against a-glucosidase was 81.67 ± 1.54%; both were lower than acarbose. We observe the effect of C. racemosa extract as anti-obesity with anti-aging by evaluating the obesity parameters in the human body for a 4-week period. There was a signifi...

Research paper thumbnail of Philanthropic Institutions’ Perspectives Regarding Challenges in the Indonesian Health Sector: A Qualitative Study

Open Access Macedonian Journal of Medical Sciences

BACKGROUND: The Indonesian Social Health Security Agency has a key role in improving the communit... more BACKGROUND: The Indonesian Social Health Security Agency has a key role in improving the community’s quality of life by providing financial access to all citizens to fulfill basic health needs. The society has received government funding for basic health needs through direct costs. On the other hand, there are also indirect costs for non-medical needs that may potentially become problems for some people. The concept of philanthropy was developed and became a significant and concrete utility in responding to Indonesian health problems. AIM: Our study aimed to explore challenges faced by the Indonesian philanthropic institutions in managing charitable giving to the health sector. METHODS: We conducted a qualitative study to explore challenges faced by the Indonesian philanthropic institutions in managing charitable giving to the health sector. RESULTS: As a result, we found that internal and external support and synchronous collaboration become a common theme of challenges in managing...

Research paper thumbnail of Effect of Sea grapes-Antioxidants Extract on Lipid Profile and PGC-1α Levels in Obese Men: 4 Weeks Randomized-Double Blind Controlled Trial

Proceedings of the Nutrition Society

Research paper thumbnail of The philanthropy's crucial role in alleviating stunting in Southeast Asian countries through research funding: a policy brief

F1000Research, Mar 17, 2022

Background: Developing countries need funding for researchers to maximize the evidence base, espe... more Background: Developing countries need funding for researchers to maximize the evidence base, especially in stunting research. This short policy is expected to provide opportunities for Southeast Asian countries to receive more research funding to stunt philanthropists. Policy and implications: Multi-sector cooperation is arguably the leading player in acceleration programs to reduce growth delays. The Stunted Reduction Acceleration Program, complemented by higher research and development expenditures (RDEs) and open policies to support philanthropic activities in Indonesia, will help improve the efficiency of stunted stunt reduction through adequate funding and investment. As evidenced by Singapore and Thailand, the increase in government budgets focused on research and development (R&D) and supportive environments, as shown by Global Philanthropy Environment Index (GPEI), prove that evidence-based and practical researches can lead to the reduction of estimated prevalence of stunting rather than innovation-stage research. Recommendations: Attention should be paid to proposing major changes to the allocation of R&D expenses and creating an environment that supports philanthropy. The challenges associated with these issues are: (1) stunted research and innovation are still left

Research paper thumbnail of How anthropological approach address social determinants of health in Asmat, Papua

Indonesia faced one of the most tragic and challenging health problems at the beginning of 2018, ... more Indonesia faced one of the most tragic and challenging health problems at the beginning of 2018, many children in Papua's Asmat Regency were suffering from malnutrition and measles. More than a thousand children were treated while 78 children under five years of age have died, mostly indigenous children. Asmat Regency is located in Indonesia's easternmost province with poor infrastructure and communication networks, also high transportation costs due to swampy regions criss-crossed by rivers, hard-to-reach from the center to the districts. Asmat's belief in their ancestors has formed their way of life and shaped their behavior, choices, and attitudes towards health issues, such as poor awareness regarding the fulfillment of daily nutritional intake, which is potentially harmful. Curative care is the highest priority in an extraordinary incident such as an outbreak or a mass-casualty disaster. However, establishment of the cultural hegemony of biomedicine will not be achi...

Research paper thumbnail of Application (Gym Fit) As a Fitness Center Marketing Tool in Digital Era

This study aims to produce an application that functions as a marketing tool for fitness centers ... more This study aims to produce an application that functions as a marketing tool for fitness centers in the digital era. This study uses the research and development (R&D) method, which consists of (1) collecting research results and information or often referred to as a preliminary study, (2) planning or planning, (3) developing an initial product or developing a preliminary form of product, ( 4) initial test or preliminary field testing, (5) revision of the first product preparation or main product revision, (6) main field testing of main field testing, (7) revision of operational product preparation or operational product revision, (8) trial operational product or operational field testing, (9) final product revision or final product revision. This application is called Gym Fit which consists of 4 main menus, namely education, profile of fitness center, personal trainer, and contact person. The results of the large-scale trial assessment of the developed product stated a total score ...

Research paper thumbnail of Identifikasi Preferensi Klien Menggunakan Analisis Konjoin DI Divisi Estetika Klinik Intan - Yogyakarta

Research paper thumbnail of Health-Preneurship: Mengapa Ilmu Kesehatan Masyarakat Membutuhkan Seorang Entrepreneur?

Damianus: Journal of Medicine, 2020

Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari b... more Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari berbagai latar belakang pendidikan. Dunia medis pun harus berhadapan dengan persaingan bisnis dalam penyediaan layanan kesehatan. Pada hakikatnya, mahasiswa kedokteran mendapatkan pembelajaran tentang bisnis dalam kurikulum Ilmu Kesehatan Masyarakat lewat materi teori manajemen. Hal tersebut tidak dapat sepenuhnya terlaksana karena keterbatasan kurikulum pembelajaran. Bisnis dalam dunia kesehatan selayaknya linear dengan pelayanan kesehatan holistik dan berkualitas, komunikasi dokter-pasien yang efektif, sehingga perjalanan proses terapeutik berlangsung efektif dan terhindar dari berbagai hal negatif seperti ketidakpuasan pasien yang berujung pada tuntutan medis.Tujuan: Artikel ini digunakan sebagai bahan ajar perkuliahan health-entrepreneurship yang bertujuan untuk mengeksplorasi potensi entrepreneurship dalam bidang kesehatan, mengidentifikasi peran ilmu kesehatan masyarakat yang potens...

Research paper thumbnail of How to Determine the Demand of Aesthetic Service: Identifying Client's Preferences by Using Conjoint Analysis

Journal of Economics and Business, 2018

This is observational-analysis study with quantitative measurement and cross-sectional method. Th... more This is observational-analysis study with quantitative measurement and cross-sectional method. The following attributes were chosen by a preselection of 26 randomly selected patients: cost of the products, travel time, experience of the aesthetic physician, method of referral, and easy to communicate / to consult. The study shows that the two most important attributes are easy to communicate / to consult and experience of the aesthetic physician. Another attributes are travel time, method of referral, and cost of the products. Conjoint analysis may help to determine client�s preferences. It also shows which levels positively or negatively contribute in every attribute.

Research paper thumbnail of Биологический возраст как оценка и критерий состояния здоровья студентов

Research paper thumbnail of Health-Preneurship: Mengapa Ilmu Kesehatan Masyarakat Membutuhkan Seorang Entrepreneur?

Damianus: Journal of Medicine

Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari b... more Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari berbagai latar belakang pendidikan. Dunia medis pun harus berhadapan dengan persaingan bisnis dalam penyediaan layanan kesehatan. Pada hakikatnya, mahasiswa kedokteran mendapatkan pembelajaran tentang bisnis dalam kurikulum Ilmu Kesehatan Masyarakat lewat materi teori manajemen. Hal tersebut tidak dapat sepenuhnya terlaksana karena keterbatasan kurikulum pembelajaran. Bisnis dalam dunia kesehatan selayaknya linear dengan pelayanan kesehatan holistik dan berkualitas, komunikasi dokter-pasien yang efektif, sehingga perjalanan proses terapeutik berlangsung efektif dan terhindar dari berbagai hal negatif seperti ketidakpuasan pasien yang berujung pada tuntutan medis.Tujuan: Artikel ini digunakan sebagai bahan ajar perkuliahan health-entrepreneurship yang bertujuan untuk mengeksplorasi potensi entrepreneurship dalam bidang kesehatan, mengidentifikasi peran ilmu kesehatan masyarakat yang potens...

Research paper thumbnail of Metabolomic Assay, Computational Screening, and Pharmacological Evaluation of Caulerpa racemosa as an Anti-obesity With Anti-aging by Altering Lipid Profile and Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α Levels

Frontiers in Nutrition

Obesity is associated with an accelerated aging process, which prevents healthy aging. Both obesi... more Obesity is associated with an accelerated aging process, which prevents healthy aging. Both obesity and aging were manifested in the peroxisome proliferator-activated receptor-γ coactivator α (PGC-1α) level. These studies fulfill the scientific gap in assembled pharmacological activity assay of Caulerpa racemosa done in a previous preclinical trial. Six major compounds from sea grape (C. racemosa) extract were evaluated using an in silico approach against human pancreatic lipase, a-glucosidase, and a-amylase to predict prospective anti-obesity candidates. The lipase inhibitory activity of the extract reached 90.30 ± 0.40%, 1.75% lower than orlistat. The a-amylase inhibitory assay of the extract was 84.07 ± 5.28%, while the inhibitory activity against a-glucosidase was 81.67 ± 1.54%; both were lower than acarbose. We observe the effect of C. racemosa extract as anti-obesity with anti-aging by evaluating the obesity parameters in the human body for a 4-week period. There was a signifi...

Research paper thumbnail of Philanthropic Institutions’ Perspectives Regarding Challenges in the Indonesian Health Sector: A Qualitative Study

Open Access Macedonian Journal of Medical Sciences

BACKGROUND: The Indonesian Social Health Security Agency has a key role in improving the communit... more BACKGROUND: The Indonesian Social Health Security Agency has a key role in improving the community’s quality of life by providing financial access to all citizens to fulfill basic health needs. The society has received government funding for basic health needs through direct costs. On the other hand, there are also indirect costs for non-medical needs that may potentially become problems for some people. The concept of philanthropy was developed and became a significant and concrete utility in responding to Indonesian health problems. AIM: Our study aimed to explore challenges faced by the Indonesian philanthropic institutions in managing charitable giving to the health sector. METHODS: We conducted a qualitative study to explore challenges faced by the Indonesian philanthropic institutions in managing charitable giving to the health sector. RESULTS: As a result, we found that internal and external support and synchronous collaboration become a common theme of challenges in managing...

Research paper thumbnail of Effect of Sea grapes-Antioxidants Extract on Lipid Profile and PGC-1α Levels in Obese Men: 4 Weeks Randomized-Double Blind Controlled Trial

Proceedings of the Nutrition Society

Research paper thumbnail of The philanthropy's crucial role in alleviating stunting in Southeast Asian countries through research funding: a policy brief

F1000Research, Mar 17, 2022

Background: Developing countries need funding for researchers to maximize the evidence base, espe... more Background: Developing countries need funding for researchers to maximize the evidence base, especially in stunting research. This short policy is expected to provide opportunities for Southeast Asian countries to receive more research funding to stunt philanthropists. Policy and implications: Multi-sector cooperation is arguably the leading player in acceleration programs to reduce growth delays. The Stunted Reduction Acceleration Program, complemented by higher research and development expenditures (RDEs) and open policies to support philanthropic activities in Indonesia, will help improve the efficiency of stunted stunt reduction through adequate funding and investment. As evidenced by Singapore and Thailand, the increase in government budgets focused on research and development (R&D) and supportive environments, as shown by Global Philanthropy Environment Index (GPEI), prove that evidence-based and practical researches can lead to the reduction of estimated prevalence of stunting rather than innovation-stage research. Recommendations: Attention should be paid to proposing major changes to the allocation of R&D expenses and creating an environment that supports philanthropy. The challenges associated with these issues are: (1) stunted research and innovation are still left

Research paper thumbnail of How anthropological approach address social determinants of health in Asmat, Papua

Indonesia faced one of the most tragic and challenging health problems at the beginning of 2018, ... more Indonesia faced one of the most tragic and challenging health problems at the beginning of 2018, many children in Papua's Asmat Regency were suffering from malnutrition and measles. More than a thousand children were treated while 78 children under five years of age have died, mostly indigenous children. Asmat Regency is located in Indonesia's easternmost province with poor infrastructure and communication networks, also high transportation costs due to swampy regions criss-crossed by rivers, hard-to-reach from the center to the districts. Asmat's belief in their ancestors has formed their way of life and shaped their behavior, choices, and attitudes towards health issues, such as poor awareness regarding the fulfillment of daily nutritional intake, which is potentially harmful. Curative care is the highest priority in an extraordinary incident such as an outbreak or a mass-casualty disaster. However, establishment of the cultural hegemony of biomedicine will not be achi...

Research paper thumbnail of Application (Gym Fit) As a Fitness Center Marketing Tool in Digital Era

This study aims to produce an application that functions as a marketing tool for fitness centers ... more This study aims to produce an application that functions as a marketing tool for fitness centers in the digital era. This study uses the research and development (R&D) method, which consists of (1) collecting research results and information or often referred to as a preliminary study, (2) planning or planning, (3) developing an initial product or developing a preliminary form of product, ( 4) initial test or preliminary field testing, (5) revision of the first product preparation or main product revision, (6) main field testing of main field testing, (7) revision of operational product preparation or operational product revision, (8) trial operational product or operational field testing, (9) final product revision or final product revision. This application is called Gym Fit which consists of 4 main menus, namely education, profile of fitness center, personal trainer, and contact person. The results of the large-scale trial assessment of the developed product stated a total score ...

Research paper thumbnail of Identifikasi Preferensi Klien Menggunakan Analisis Konjoin DI Divisi Estetika Klinik Intan - Yogyakarta

Research paper thumbnail of Health-Preneurship: Mengapa Ilmu Kesehatan Masyarakat Membutuhkan Seorang Entrepreneur?

Damianus: Journal of Medicine, 2020

Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari b... more Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari berbagai latar belakang pendidikan. Dunia medis pun harus berhadapan dengan persaingan bisnis dalam penyediaan layanan kesehatan. Pada hakikatnya, mahasiswa kedokteran mendapatkan pembelajaran tentang bisnis dalam kurikulum Ilmu Kesehatan Masyarakat lewat materi teori manajemen. Hal tersebut tidak dapat sepenuhnya terlaksana karena keterbatasan kurikulum pembelajaran. Bisnis dalam dunia kesehatan selayaknya linear dengan pelayanan kesehatan holistik dan berkualitas, komunikasi dokter-pasien yang efektif, sehingga perjalanan proses terapeutik berlangsung efektif dan terhindar dari berbagai hal negatif seperti ketidakpuasan pasien yang berujung pada tuntutan medis.Tujuan: Artikel ini digunakan sebagai bahan ajar perkuliahan health-entrepreneurship yang bertujuan untuk mengeksplorasi potensi entrepreneurship dalam bidang kesehatan, mengidentifikasi peran ilmu kesehatan masyarakat yang potens...

Research paper thumbnail of How to Determine the Demand of Aesthetic Service: Identifying Client's Preferences by Using Conjoint Analysis

Journal of Economics and Business, 2018

This is observational-analysis study with quantitative measurement and cross-sectional method. Th... more This is observational-analysis study with quantitative measurement and cross-sectional method. The following attributes were chosen by a preselection of 26 randomly selected patients: cost of the products, travel time, experience of the aesthetic physician, method of referral, and easy to communicate / to consult. The study shows that the two most important attributes are easy to communicate / to consult and experience of the aesthetic physician. Another attributes are travel time, method of referral, and cost of the products. Conjoint analysis may help to determine client�s preferences. It also shows which levels positively or negatively contribute in every attribute.

Research paper thumbnail of Биологический возраст как оценка и критерий состояния здоровья студентов

Research paper thumbnail of Health-Preneurship: Mengapa Ilmu Kesehatan Masyarakat Membutuhkan Seorang Entrepreneur?

Damianus: Journal of Medicine

Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari b... more Pendahuluan: Dunia bisnis dalam beberapa tahun terakhir banyak diminati oleh generasi muda dari berbagai latar belakang pendidikan. Dunia medis pun harus berhadapan dengan persaingan bisnis dalam penyediaan layanan kesehatan. Pada hakikatnya, mahasiswa kedokteran mendapatkan pembelajaran tentang bisnis dalam kurikulum Ilmu Kesehatan Masyarakat lewat materi teori manajemen. Hal tersebut tidak dapat sepenuhnya terlaksana karena keterbatasan kurikulum pembelajaran. Bisnis dalam dunia kesehatan selayaknya linear dengan pelayanan kesehatan holistik dan berkualitas, komunikasi dokter-pasien yang efektif, sehingga perjalanan proses terapeutik berlangsung efektif dan terhindar dari berbagai hal negatif seperti ketidakpuasan pasien yang berujung pada tuntutan medis.Tujuan: Artikel ini digunakan sebagai bahan ajar perkuliahan health-entrepreneurship yang bertujuan untuk mengeksplorasi potensi entrepreneurship dalam bidang kesehatan, mengidentifikasi peran ilmu kesehatan masyarakat yang potens...