John Chelico - Academia.edu (original) (raw)
Papers by John Chelico
Five bacterial isolates were previously isolated from seawaters with petroleum oil of Tianjin por... more Five bacterial isolates were previously isolated from seawaters with petroleum oil of Tianjin port. These isolates were detected under conditions that contained various types of hydrocarbon substances and different hydrocarbons degradability of the mixed strains. It turned out that the CH-series strains have a good degradation effect for phenanthrene, fluoranthene and pristane, for benzo(а)pyrene, two sets of experiments have a low degradation rate. These isolateds were grown on five concentration of n-Nonadecane as the sole source of carbnon. The abilities of these islotes to degrade n-Nonadecane have been investigated. For n-Nonadecane degradation the most efficient strain was CH2 which degraded 97.54%, 99.72%, 98.64%, 93.
Journal of the American Academy of Dermatology
JAMA, Apr 22, 2020
; and the Northwell COVID-19 Research Consortium IMPORTANCE There is limited information describi... more ; and the Northwell COVID-19 Research Consortium IMPORTANCE There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19). OBJECTIVE To describe the clinical characteristics and outcomes of patients with COVID-19 hospitalized in a US health care system. DESIGN, SETTING, AND PARTICIPANTS Case series of patients with COVID-19 admitted to 12 hospitals in New York City, Long Island, and Westchester County, New York, within the Northwell Health system. The study included all sequentially hospitalized patients between March 1, 2020, and April 4, 2020, inclusive of these dates. EXPOSURES Confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by positive result on polymerase chain reaction testing of a nasopharyngeal sample among patients requiring admission. MAIN OUTCOMES AND MEASURES Clinical outcomes during hospitalization, such as invasive mechanical ventilation, kidney replacement therapy, and death. Demographics, baseline comorbidities, presenting vital signs, and test results were also collected. RESULTS A total of 5700 patients were included (median age, 63 years [interquartile range {IQR}, 52-75; range, 0-107 years]; 39.7% female). The most common comorbidities were hypertension (3026; 56.6%), obesity (1737; 41.7%), and diabetes (1808; 33.8%). At triage, 30.7% of patients were febrile, 17.3% had a respiratory rate greater than 24 breaths/minute, and 27.8% received supplemental oxygen. The rate of respiratory virus co-infection was 2.1%. Outcomes were assessed for 2634 patients who were discharged or had died at the study end point. During hospitalization, 373 patients (14.2%) (median age, 68 years [IQR, 56-78]; 33.5% female) were treated in the intensive care unit care, 320 (12.2%) received invasive mechanical ventilation, 81 (3.2%) were treated with kidney replacement therapy, and 553 (21%) died. As of April 4, 2020, for patients requiring mechanical ventilation (n = 1151, 20.2%), 38 (3.3%) were discharged alive, 282 (24.5%) died, and 831 (72.2%) remained in hospital. The median postdischarge follow-up time was 4.4 days (IQR, 2.2-9.3). A total of 45 patients (2.2%) were readmitted during the study period. The median time to readmission was 3 days (IQR, 1.0-4.5) for readmitted patients. Among the 3066 patients who remained hospitalized at the final study follow-up date (median age, 65 years [IQR, 54-75]), the median follow-up at time of censoring was 4.5 days (IQR, 2.4-8.1). CONCLUSIONS AND RELEVANCE This case series provides characteristics and early outcomes of sequentially hospitalized patients with confirmed COVID-19 in the New York City area.
Amia Annual Symposium Proceedings Amia Symposium Amia Symposium, Feb 1, 2007
As the clinical data warehouse of the New York Presbyterian Hospital has evolved innovative metho... more As the clinical data warehouse of the New York Presbyterian Hospital has evolved innovative methods of integrating new data sources and providing more effective and efficient data reporting and analysis need to be explored. We designed and implemented a new clinical data warehouse architecture to handle the integration of disparate clinical databases in the institution. By examining the way downstream systems are populated and streamlining the way data is stored we create a virtual clinical data warehouse that is adaptable to future needs of the organization.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium, Jan 6, 2008
Biomedical informatics students who choose to study clinical information systems may not have sig... more Biomedical informatics students who choose to study clinical information systems may not have significant clinical experience. A course was designed to "acculturate" these students to the practice of medicine through case-based presentations that span three competency areas: biomedicine, clinical workflow and practice, and applications in clinical informatics.
Journal of Biomedical Informatics, 2007
Current electronic health record systems are primarily clinical in focus, designed to provide pat... more Current electronic health record systems are primarily clinical in focus, designed to provide patient-level data and provider-level decision support. Adapting EHR systems to serve public health needs provides the possibility of enormous advances for public health practice and policy. In this review, we evaluate EHR functionality and map it to the three core functions of public health: assessment, policy development, and assurance. In doing so, we identify and discuss important design, implementation, and methodological issues with current systems. For example, in order to support public health's traditional focus on preventive health and socio-behavioral factors, EHR data models would need to be expanded to incorporate environmental, psychosocial, and other non-medical data elements, and workflow would have to be examined to determine the optimal way of collecting these data. We also argue that redesigning EHR systems to support public health offers benefits not only to the public health system but also to consumers, health-care institutions, and individual providers.
Five bacterial isolates were previously isolated from seawaters with petroleum oil of Tianjin por... more Five bacterial isolates were previously isolated from seawaters with petroleum oil of Tianjin port. These isolates were detected under conditions that contained various types of hydrocarbon substances and different hydrocarbons degradability of the mixed strains. It turned out that the CH-series strains have a good degradation effect for phenanthrene, fluoranthene and pristane, for benzo(а)pyrene, two sets of experiments have a low degradation rate. These isolateds were grown on five concentration of n-Nonadecane as the sole source of carbnon. The abilities of these islotes to degrade n-Nonadecane have been investigated. For n-Nonadecane degradation the most efficient strain was CH2 which degraded 97.54%, 99.72%, 98.64%, 93.
Journal of the American Academy of Dermatology
JAMA, Apr 22, 2020
; and the Northwell COVID-19 Research Consortium IMPORTANCE There is limited information describi... more ; and the Northwell COVID-19 Research Consortium IMPORTANCE There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19). OBJECTIVE To describe the clinical characteristics and outcomes of patients with COVID-19 hospitalized in a US health care system. DESIGN, SETTING, AND PARTICIPANTS Case series of patients with COVID-19 admitted to 12 hospitals in New York City, Long Island, and Westchester County, New York, within the Northwell Health system. The study included all sequentially hospitalized patients between March 1, 2020, and April 4, 2020, inclusive of these dates. EXPOSURES Confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by positive result on polymerase chain reaction testing of a nasopharyngeal sample among patients requiring admission. MAIN OUTCOMES AND MEASURES Clinical outcomes during hospitalization, such as invasive mechanical ventilation, kidney replacement therapy, and death. Demographics, baseline comorbidities, presenting vital signs, and test results were also collected. RESULTS A total of 5700 patients were included (median age, 63 years [interquartile range {IQR}, 52-75; range, 0-107 years]; 39.7% female). The most common comorbidities were hypertension (3026; 56.6%), obesity (1737; 41.7%), and diabetes (1808; 33.8%). At triage, 30.7% of patients were febrile, 17.3% had a respiratory rate greater than 24 breaths/minute, and 27.8% received supplemental oxygen. The rate of respiratory virus co-infection was 2.1%. Outcomes were assessed for 2634 patients who were discharged or had died at the study end point. During hospitalization, 373 patients (14.2%) (median age, 68 years [IQR, 56-78]; 33.5% female) were treated in the intensive care unit care, 320 (12.2%) received invasive mechanical ventilation, 81 (3.2%) were treated with kidney replacement therapy, and 553 (21%) died. As of April 4, 2020, for patients requiring mechanical ventilation (n = 1151, 20.2%), 38 (3.3%) were discharged alive, 282 (24.5%) died, and 831 (72.2%) remained in hospital. The median postdischarge follow-up time was 4.4 days (IQR, 2.2-9.3). A total of 45 patients (2.2%) were readmitted during the study period. The median time to readmission was 3 days (IQR, 1.0-4.5) for readmitted patients. Among the 3066 patients who remained hospitalized at the final study follow-up date (median age, 65 years [IQR, 54-75]), the median follow-up at time of censoring was 4.5 days (IQR, 2.4-8.1). CONCLUSIONS AND RELEVANCE This case series provides characteristics and early outcomes of sequentially hospitalized patients with confirmed COVID-19 in the New York City area.
Amia Annual Symposium Proceedings Amia Symposium Amia Symposium, Feb 1, 2007
As the clinical data warehouse of the New York Presbyterian Hospital has evolved innovative metho... more As the clinical data warehouse of the New York Presbyterian Hospital has evolved innovative methods of integrating new data sources and providing more effective and efficient data reporting and analysis need to be explored. We designed and implemented a new clinical data warehouse architecture to handle the integration of disparate clinical databases in the institution. By examining the way downstream systems are populated and streamlining the way data is stored we create a virtual clinical data warehouse that is adaptable to future needs of the organization.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium, Jan 6, 2008
Biomedical informatics students who choose to study clinical information systems may not have sig... more Biomedical informatics students who choose to study clinical information systems may not have significant clinical experience. A course was designed to "acculturate" these students to the practice of medicine through case-based presentations that span three competency areas: biomedicine, clinical workflow and practice, and applications in clinical informatics.
Journal of Biomedical Informatics, 2007
Current electronic health record systems are primarily clinical in focus, designed to provide pat... more Current electronic health record systems are primarily clinical in focus, designed to provide patient-level data and provider-level decision support. Adapting EHR systems to serve public health needs provides the possibility of enormous advances for public health practice and policy. In this review, we evaluate EHR functionality and map it to the three core functions of public health: assessment, policy development, and assurance. In doing so, we identify and discuss important design, implementation, and methodological issues with current systems. For example, in order to support public health's traditional focus on preventive health and socio-behavioral factors, EHR data models would need to be expanded to incorporate environmental, psychosocial, and other non-medical data elements, and workflow would have to be examined to determine the optimal way of collecting these data. We also argue that redesigning EHR systems to support public health offers benefits not only to the public health system but also to consumers, health-care institutions, and individual providers.