Jorge Vicente Lopes da Silva (original) (raw)

Papers by Jorge Vicente Lopes da Silva

Orientadores: Rubens Maciel Filho, Marcelo de Carvalho ReisTese (doutorado) - Universidade Estadu... more Orientadores: Rubens Maciel Filho, Marcelo de Carvalho ReisTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia QuimicaResumo: Laboratórios de pesquisa universitários são ambientes únicos com intensas atividades do conhecimento. Porém, não é raro verificar uma falta de organização sistemática de seus processos de gestão e a integração satisfatória de estratégias, missão, pessoal, infra-estrutura e atividades do conhecimento. Esta tese discute as motivações, necessidades e propõe um modelo de capacidade para a gestão estratégica desse ambiente. O modelo tem por objetivo auxiliar na avaliação e melhoria da capacidade de seus processos e servir como referência na gestão de laboratórios. O modelo é composto de 17 processos divididos em quatro grupos: gestão estratégica, infra-estrutura, gestão do conhecimento, e gestão de pessoal e cultura. Cada processo individualmente é composto de resultados, práticas base e artefatos. Os processos foram criados a partir de l...

Research, Society and Development

This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) syst... more This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) system, to assess the influence on image accuracy by different voxel sizes and the presence of soft tissue. Tomographic acquisition was performed in a fresh (F) and dry (D) pork jaw with voxel sizes of 0.4, 0.3 and 0.25 mm. The gold standard was obtained by scanning dry jaws covered with barium sulfate with a voxel size of 0.25 mm. The images were treated in the MIMICS® program, and noise areas were removed manually, using a fixed threshold for the purpose of generating 3D printing windows. Each window was virtually overlaid with the gold standard using the MeshLab software, obtaining absolute error values ​​between the meshes, generating a map of discrepancies. Significant differences were found between windows D 0.30 vs. F 0.30, D 0.30 vs. F 0.25, D 0.30 vs. D 0.25, D 0.30 vs. F 0.40, F 0.30 vs. D 0.25, F 0.25 vs. D 0.25, F 0.25 vs. D 0.40, D 0.25 vs. F 0.40, D 0.25 vs. D 0.40 and F 0.40 v...

Research, Society and Development, 2020

This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) syst... more This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) system, to assess the influence on image accuracy by different voxel sizes and the presence of soft tissue. Tomographic acquisition was performed in a fresh (F) and dry (D) pork jaw with voxel sizes of 0.4, 0.3 and 0.25 mm. The gold standard was obtained by scanning dry jaws covered with barium sulfate with a voxel size of 0.25 mm. The images were treated in the MIMICS program, and noise areas were removed manually, using a fixed threshold for the purpose of generating 3D printing windows. Each window was virtually overlaid with the gold standard using the MeshLab software, obtaining absolute error values between the meshes, generating a map of discrepancies. Significant differences were found between windows D 0.30 vs. F 0.30, D 0.30 vs. F 0.25, D 0.30 vs. D 0.25, D 0.30 vs. F 0.40, F 0.30 vs. D 0.25, F 0.25 vs. D 0.25, F 0.25 vs. D 0.40, D 0.25 vs. F 0.40, D 0.25 vs. D 0.40 and F 0.40 vs. ...

Introducao: O planejamento pre-operatorio de cirurgias complexas da regiao de cabeca e pescoco ut... more Introducao: O planejamento pre-operatorio de cirurgias complexas da regiao de cabeca e pescoco utiliza usualmente imagens de tomografia computadorizada (TC) ou ressonância nuclear magnetica (RNM). Uma reconstrucao tridimensional completa das estruturas envolvidas nessas regioes pode propiciar um acesso privilegiado as areas anatomicas de interesse, explicitando detalhes que nao podem ser vistos nos filmes radiograficos comuns. A prototipagem rapida (PR) consiste em um grupo de processos utilizados para produzir objetos em tres dimensoes pela adicao de camadas de material. O processo de sinterizacao seletiva a laser (SLS – Selective Laser Sintering) e uma das tecnicas disponiveis de PR, que pode ser usada para produzir prototipos biomedicos obtidos a partir de imagens de TC e RNM. Esses prototipos sao utilizados com objetivos didaticos, na fabricacao de proteses personalizadas, no diagnostico e planejamento de cirurgias crânio-faciais, incluindo as neoplasias e facilitando tambem a c...

Resumo Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que util... more Resumo Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que utiliza as ideias comuns de simulações como métodos probabilísticos preditivos e cálculos de energia aplicados a dois frameworks: o mecânico e o biológico. Em resumo, o mecânico utilizaria a análise de elementos finitos para observar comportamentos fluidodinâmicos como pressão hidrostática, elasticidade e fluxo de fluidos. Já o biológico utilizaria sistemas complexos de interação intra, inter e extracelular para analisar comportamentos como divisão celular, difusão e quimiotaxia das unidades básicas que compõem o órgão.

Instituição: Centro de Tecnologia da Informação Renato Archer – CTI. Campinas / SP – Brasil. Corr... more Instituição: Centro de Tecnologia da Informação Renato Archer – CTI. Campinas / SP – Brasil. Correspondência: José Augusto Gomes Pereira de Oliveira Divisão de Tecnologias Tridimensionais (DT3D) do Centro de Tecnologia da Informação Renato Archer CTI MCTI Rodovia Dom Pedro I (SP-65), Km 143,6 Campinas / SP – Brasil E-mail: draugustophd@gmail.com Artigo recebido em 06/05/2015; aceito para publicação em 23/09/2016; publicado online em 15/10/2016. Conflito de interesse: não há. Fonte de fomento: não há. Relato de Caso

This article introduces a Method Framework for Engineering Process Capability Models. This method... more This article introduces a Method Framework for Engineering Process Capability Models. This method framework supports the definition of methods or processes to engineer a Process Capability Model. The main goal is that the method framework is a useful proposal for developing methods and processes for engineering Process Capability Models. The method framework defines seven steps and seven customizations rules.

We present a detailed step-by-step approach for the low-cost production and surgical implantation... more We present a detailed step-by-step approach for the low-cost production and surgical implantation of cranial prostheses, aimed at restoring aesthetics, cerebral protection, and facilitating neurological rehabilitation. This protocol uses combined scan computed tomography (CT) cross-sectional images, in DICOM format, along with a 3D printing (additive manufacturing) setup. The in-house developed software InVesalius®️ is an open-source tool for medical imaging manipulation. The protocol describes image acquisition (CT scanning) procedures, and image post-processing procedures such as image segmentation, surface/volume rendering, mesh generation of a 3D digital model of the cranial defect and the desired prostheses, and their preparation for use in 3D printers. Furthermore, the protocol describes a detailed powder bed fusion additive manufacturing process, known as Selective Laser Sintering (SLS), using Polyamide (PA12) as feedstock to produce a 3-piece customized printed set per patie...

Progress in Additive Manufacturing

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome cor... more The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread through more than 180 countries, leading to diverse health systems overload around the world. Because of the high number of patients and the supply chain disruption, it generated a shortage of medical devices and personal protective equipment. In this context, initiatives from the additive manufacturing community emerged to fight the lack of devices. Diverse designs were produced and are currently being used in hospitals by patients and health workers. However, as some devices must follow strict standards, these products may not fulfill these standards. Therefore, to ensure the user's health, there is a need for understanding each device, their usage, and standards. This study reviews the use of additive manufacturing during COVID-19 pandemic. It gathers the source of several 3D printed devices such as face shields, face masks, valves, nasopharyngeal swabs, and others, discussing their use and regulatory issues. In this regard, the major drawbacks of the technology, addressed for the next pandemic scenario, are highlighted. Finally, some insights of the future of additive manufacturing during emergency are given and discussed.

Sitientibus Série Ciências Físicas

Este trabalho é relacionado com a engenharia de reabilitação, e mostra a evolução e a diversidade... more Este trabalho é relacionado com a engenharia de reabilitação, e mostra a evolução e a diversidade de formas e aplicações da física em algumas das técnicas de produção de próteses biomecânicas, seja na definição, construção e projeto da estrutura em seus diversos modelos, seja nos aspectos mecânicos, funcionais e operacionais, a exemplo da construção e do acionamento de próteses para indivíduos com amputação parcial dos membros superiores. O artigo apresenta a construção de dois modelos de próteses de apreensão. Um primeiro modelo do tipo acionamento com um atuador baseado em Shape Memory Alloy - SMA, e estudado através de três protótipos, um artesanal, um feito por usinagem convencional, e um terceiro por prototipagem rápida, sendo este último dedicado e integrado na estrutura da prótese. A proposta do segundo modelo, uma próotese acionada por motor de corrente contínua também é apresentada, sendo este integrado à garra, através de um redutor de velocidade. O projeto do modelo usand...

Surgical Neurology International

Background: Cranial reconstruction surgery is a procedure used as an attempt to reestablish the c... more Background: Cranial reconstruction surgery is a procedure used as an attempt to reestablish the cranial bone anatomy. This study evaluates the symptomatic and aesthetic improvement of patients with cranial defects secondary to decompressive craniectomies after cranial reconstruction with customized polymethyl methacrylate (PMMA) prostheses. Secondly, we aim to divide our experience in the production of these prostheses with a low-cost method. Methods: A prospective study was carried out with patients submitted to cranioplasty at the Hospital da Restauração between 2014 and 2017. A total of 63 cranioplasties were performed using customized PMMA prosthesis produced by 3D impression molds. All patients underwent a functional and aesthetic evaluation questionnaire in the preoperative period and in the sixth postoperative month. Results: Sixty-three patients underwent cranioplasty with a mean age of 33 years, ranging from 13 to 58 years, 55 males and 8 females. The mean area of the defect was 147 cm 2. The mean postoperative follow-up of the patients was 21 months, ranging from 6 to 33 months. Fifty-five patients attended the 6-month postoperative consultation. All patients presented symptomatic improvement after reconstruction of the skull. The infection rate was 3.2%, 4.8% of extrusion, 1.6% of prosthesis How to cite this article: Maricevich JPBR, Cezar-Junior AB, de Oliveira-Junior EX, Veras e Silva JAM, da Silva JVL, Nunes AA, et al. Functional and aesthetic evaluation after cranial reconstruction with polymethyl methacrylate prostheses using low-cost 3D printing templates in patients with cranial defects secondary to decompressive craniectomies: A prospective study. Surg Neurol Int 2019;10:1. http://surgicalneurologyint.com/Functional-and-aesthetic-evaluation-after-cranial-reconstruction-with-polymethyl-methacrylate-prostheses-using-low-cost-3D-printingtemplates-in-patients-with-cranial-defects-secondary-to-decompressive-craniectomies:-A-prospective-study/ This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

Anais do Encontro Nacional de Engenharia de Produção

Selective Laser Sintering (SLS), which allows to obtain a desired customized shape, excelent to p... more Selective Laser Sintering (SLS), which allows to obtain a desired customized shape, excelent to prepare implants molds. Thermal processing conditions during Additive Manufacturing (AM) is significant influence on crystallinity and morfology conditions. In this research, we have studied the relationship between SLS parameters and the desired PEEK morphology, roughness and crystallinity. All results showed that the temperature-control of the 3D printing method has a potential influence on the morphology layer by layer and it could be a potential to produce cranial implants, especially due to rough surface presented. However if uncontrolled the cooling temperature can reduce crystallinity probably impacting the 3D structure resistance.

Journal of neuroscience methods, Jan 24, 2018

Neuronavigation provides visual guidance of an instrument during procedures of neurological inter... more Neuronavigation provides visual guidance of an instrument during procedures of neurological interventions, and has been shown to be a valuable tool for accurately positioning transcranial magnetic stimulation (TMS) coils relative to an individual's anatomy. Despite the importance of neuronavigation, its high cost, low portability, and low availability of magnetic resonance imaging facilities limit its insertion in research and clinical environments. We have developed and validated the InVesalius Navigator as the first free, open-source software for image-guided navigated TMS, compatible with multiple tracking devices. A point-based, co-registration algorithm and a guiding interface were designed for tracking any instrument (e.g. TMS coils) relative to an individual's anatomy. Localization, precision errors, and repeatability were measured for two tracking devices during navigation in a phantom and in a simulated TMS study. Errors were measured in two commercial navigated TMS...

XXV Congresso de Iniciação Científica da Unicamp, 2017

Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que utiliza as ... more Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que utiliza as ideias comuns de simulações-como métodos probabilísticos preditivos e cálculos de energia-aplicados a dois frameworks: o mecânico e o biológico. Em resumo, o mecânico utilizaria a análise de elementos finitos para observar comportamentos fluidodinâmicos como pressão hidrostática, elasticidade e fluxo de fluidos. Já o biológico utilizaria sistemas complexos de interação intra, inter e extracelular para analisar comportamentos como divisão celular, difusão e quimiotaxia das unidades básicas que compõem o órgão.

Procedia CIRP, 2016

Abstract The long-term success of implants depends on rapid healing and safe integration with bod... more Abstract The long-term success of implants depends on rapid healing and safe integration with body. In the case of orthopaedic and dental implants it was found that geometry and surface topography are crucial for short and long-term success of the implant, due to its effects in osseointegration. Properties of implant surfaces have been studied in the last decade in a concentrated effort to improve osseointegration process and implant success. Several researchers have proved that roughness of implant surface is related to healing time and integration between the implants and the bone, but the parameters on the surface creation are not fully controllable with current processes. In this work, computational algorithms are proposed for implant surface design in order to control the parameters required for this application. As a result it is presented an open-source software tool, called POMES - Porous and Modifications for Engineering Surfaces -, to design porous/roughness on top of surfaces in any geometry. Additionally, an example model was fabricated using POMES and additive manufacturing.

Independent Journal of Management & Production, 2015

Based on a case study, this paper presents a methodology to adopt ISO 9001 standards for organiza... more Based on a case study, this paper presents a methodology to adopt ISO 9001 standards for organizations, which make use of additive manufacturing to build products for medical use. Starting with a conceptual model, guidelines were identified to guide planning and operation of the management system, as well as its maintenance and improvement.

Orientadores: Rubens Maciel Filho, Marcelo de Carvalho ReisTese (doutorado) - Universidade Estadu... more Orientadores: Rubens Maciel Filho, Marcelo de Carvalho ReisTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia QuimicaResumo: Laboratórios de pesquisa universitários são ambientes únicos com intensas atividades do conhecimento. Porém, não é raro verificar uma falta de organização sistemática de seus processos de gestão e a integração satisfatória de estratégias, missão, pessoal, infra-estrutura e atividades do conhecimento. Esta tese discute as motivações, necessidades e propõe um modelo de capacidade para a gestão estratégica desse ambiente. O modelo tem por objetivo auxiliar na avaliação e melhoria da capacidade de seus processos e servir como referência na gestão de laboratórios. O modelo é composto de 17 processos divididos em quatro grupos: gestão estratégica, infra-estrutura, gestão do conhecimento, e gestão de pessoal e cultura. Cada processo individualmente é composto de resultados, práticas base e artefatos. Os processos foram criados a partir de l...

Research, Society and Development

This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) syst... more This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) system, to assess the influence on image accuracy by different voxel sizes and the presence of soft tissue. Tomographic acquisition was performed in a fresh (F) and dry (D) pork jaw with voxel sizes of 0.4, 0.3 and 0.25 mm. The gold standard was obtained by scanning dry jaws covered with barium sulfate with a voxel size of 0.25 mm. The images were treated in the MIMICS® program, and noise areas were removed manually, using a fixed threshold for the purpose of generating 3D printing windows. Each window was virtually overlaid with the gold standard using the MeshLab software, obtaining absolute error values ​​between the meshes, generating a map of discrepancies. Significant differences were found between windows D 0.30 vs. F 0.30, D 0.30 vs. F 0.25, D 0.30 vs. D 0.25, D 0.30 vs. F 0.40, F 0.30 vs. D 0.25, F 0.25 vs. D 0.25, F 0.25 vs. D 0.40, D 0.25 vs. F 0.40, D 0.25 vs. D 0.40 and F 0.40 v...

Research, Society and Development, 2020

This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) syst... more This study compared the acquisition protocols of the Conical Beam Computed Tomography (CBCT) system, to assess the influence on image accuracy by different voxel sizes and the presence of soft tissue. Tomographic acquisition was performed in a fresh (F) and dry (D) pork jaw with voxel sizes of 0.4, 0.3 and 0.25 mm. The gold standard was obtained by scanning dry jaws covered with barium sulfate with a voxel size of 0.25 mm. The images were treated in the MIMICS program, and noise areas were removed manually, using a fixed threshold for the purpose of generating 3D printing windows. Each window was virtually overlaid with the gold standard using the MeshLab software, obtaining absolute error values between the meshes, generating a map of discrepancies. Significant differences were found between windows D 0.30 vs. F 0.30, D 0.30 vs. F 0.25, D 0.30 vs. D 0.25, D 0.30 vs. F 0.40, F 0.30 vs. D 0.25, F 0.25 vs. D 0.25, F 0.25 vs. D 0.40, D 0.25 vs. F 0.40, D 0.25 vs. D 0.40 and F 0.40 vs. ...

Introducao: O planejamento pre-operatorio de cirurgias complexas da regiao de cabeca e pescoco ut... more Introducao: O planejamento pre-operatorio de cirurgias complexas da regiao de cabeca e pescoco utiliza usualmente imagens de tomografia computadorizada (TC) ou ressonância nuclear magnetica (RNM). Uma reconstrucao tridimensional completa das estruturas envolvidas nessas regioes pode propiciar um acesso privilegiado as areas anatomicas de interesse, explicitando detalhes que nao podem ser vistos nos filmes radiograficos comuns. A prototipagem rapida (PR) consiste em um grupo de processos utilizados para produzir objetos em tres dimensoes pela adicao de camadas de material. O processo de sinterizacao seletiva a laser (SLS – Selective Laser Sintering) e uma das tecnicas disponiveis de PR, que pode ser usada para produzir prototipos biomedicos obtidos a partir de imagens de TC e RNM. Esses prototipos sao utilizados com objetivos didaticos, na fabricacao de proteses personalizadas, no diagnostico e planejamento de cirurgias crânio-faciais, incluindo as neoplasias e facilitando tambem a c...

Resumo Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que util... more Resumo Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que utiliza as ideias comuns de simulações como métodos probabilísticos preditivos e cálculos de energia aplicados a dois frameworks: o mecânico e o biológico. Em resumo, o mecânico utilizaria a análise de elementos finitos para observar comportamentos fluidodinâmicos como pressão hidrostática, elasticidade e fluxo de fluidos. Já o biológico utilizaria sistemas complexos de interação intra, inter e extracelular para analisar comportamentos como divisão celular, difusão e quimiotaxia das unidades básicas que compõem o órgão.

Instituição: Centro de Tecnologia da Informação Renato Archer – CTI. Campinas / SP – Brasil. Corr... more Instituição: Centro de Tecnologia da Informação Renato Archer – CTI. Campinas / SP – Brasil. Correspondência: José Augusto Gomes Pereira de Oliveira Divisão de Tecnologias Tridimensionais (DT3D) do Centro de Tecnologia da Informação Renato Archer CTI MCTI Rodovia Dom Pedro I (SP-65), Km 143,6 Campinas / SP – Brasil E-mail: draugustophd@gmail.com Artigo recebido em 06/05/2015; aceito para publicação em 23/09/2016; publicado online em 15/10/2016. Conflito de interesse: não há. Fonte de fomento: não há. Relato de Caso

This article introduces a Method Framework for Engineering Process Capability Models. This method... more This article introduces a Method Framework for Engineering Process Capability Models. This method framework supports the definition of methods or processes to engineer a Process Capability Model. The main goal is that the method framework is a useful proposal for developing methods and processes for engineering Process Capability Models. The method framework defines seven steps and seven customizations rules.

We present a detailed step-by-step approach for the low-cost production and surgical implantation... more We present a detailed step-by-step approach for the low-cost production and surgical implantation of cranial prostheses, aimed at restoring aesthetics, cerebral protection, and facilitating neurological rehabilitation. This protocol uses combined scan computed tomography (CT) cross-sectional images, in DICOM format, along with a 3D printing (additive manufacturing) setup. The in-house developed software InVesalius®️ is an open-source tool for medical imaging manipulation. The protocol describes image acquisition (CT scanning) procedures, and image post-processing procedures such as image segmentation, surface/volume rendering, mesh generation of a 3D digital model of the cranial defect and the desired prostheses, and their preparation for use in 3D printers. Furthermore, the protocol describes a detailed powder bed fusion additive manufacturing process, known as Selective Laser Sintering (SLS), using Polyamide (PA12) as feedstock to produce a 3-piece customized printed set per patie...

Progress in Additive Manufacturing

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome cor... more The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread through more than 180 countries, leading to diverse health systems overload around the world. Because of the high number of patients and the supply chain disruption, it generated a shortage of medical devices and personal protective equipment. In this context, initiatives from the additive manufacturing community emerged to fight the lack of devices. Diverse designs were produced and are currently being used in hospitals by patients and health workers. However, as some devices must follow strict standards, these products may not fulfill these standards. Therefore, to ensure the user's health, there is a need for understanding each device, their usage, and standards. This study reviews the use of additive manufacturing during COVID-19 pandemic. It gathers the source of several 3D printed devices such as face shields, face masks, valves, nasopharyngeal swabs, and others, discussing their use and regulatory issues. In this regard, the major drawbacks of the technology, addressed for the next pandemic scenario, are highlighted. Finally, some insights of the future of additive manufacturing during emergency are given and discussed.

Sitientibus Série Ciências Físicas

Este trabalho é relacionado com a engenharia de reabilitação, e mostra a evolução e a diversidade... more Este trabalho é relacionado com a engenharia de reabilitação, e mostra a evolução e a diversidade de formas e aplicações da física em algumas das técnicas de produção de próteses biomecânicas, seja na definição, construção e projeto da estrutura em seus diversos modelos, seja nos aspectos mecânicos, funcionais e operacionais, a exemplo da construção e do acionamento de próteses para indivíduos com amputação parcial dos membros superiores. O artigo apresenta a construção de dois modelos de próteses de apreensão. Um primeiro modelo do tipo acionamento com um atuador baseado em Shape Memory Alloy - SMA, e estudado através de três protótipos, um artesanal, um feito por usinagem convencional, e um terceiro por prototipagem rápida, sendo este último dedicado e integrado na estrutura da prótese. A proposta do segundo modelo, uma próotese acionada por motor de corrente contínua também é apresentada, sendo este integrado à garra, através de um redutor de velocidade. O projeto do modelo usand...

Surgical Neurology International

Background: Cranial reconstruction surgery is a procedure used as an attempt to reestablish the c... more Background: Cranial reconstruction surgery is a procedure used as an attempt to reestablish the cranial bone anatomy. This study evaluates the symptomatic and aesthetic improvement of patients with cranial defects secondary to decompressive craniectomies after cranial reconstruction with customized polymethyl methacrylate (PMMA) prostheses. Secondly, we aim to divide our experience in the production of these prostheses with a low-cost method. Methods: A prospective study was carried out with patients submitted to cranioplasty at the Hospital da Restauração between 2014 and 2017. A total of 63 cranioplasties were performed using customized PMMA prosthesis produced by 3D impression molds. All patients underwent a functional and aesthetic evaluation questionnaire in the preoperative period and in the sixth postoperative month. Results: Sixty-three patients underwent cranioplasty with a mean age of 33 years, ranging from 13 to 58 years, 55 males and 8 females. The mean area of the defect was 147 cm 2. The mean postoperative follow-up of the patients was 21 months, ranging from 6 to 33 months. Fifty-five patients attended the 6-month postoperative consultation. All patients presented symptomatic improvement after reconstruction of the skull. The infection rate was 3.2%, 4.8% of extrusion, 1.6% of prosthesis How to cite this article: Maricevich JPBR, Cezar-Junior AB, de Oliveira-Junior EX, Veras e Silva JAM, da Silva JVL, Nunes AA, et al. Functional and aesthetic evaluation after cranial reconstruction with polymethyl methacrylate prostheses using low-cost 3D printing templates in patients with cranial defects secondary to decompressive craniectomies: A prospective study. Surg Neurol Int 2019;10:1. http://surgicalneurologyint.com/Functional-and-aesthetic-evaluation-after-cranial-reconstruction-with-polymethyl-methacrylate-prostheses-using-low-cost-3D-printingtemplates-in-patients-with-cranial-defects-secondary-to-decompressive-craniectomies:-A-prospective-study/ This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

Anais do Encontro Nacional de Engenharia de Produção

Selective Laser Sintering (SLS), which allows to obtain a desired customized shape, excelent to p... more Selective Laser Sintering (SLS), which allows to obtain a desired customized shape, excelent to prepare implants molds. Thermal processing conditions during Additive Manufacturing (AM) is significant influence on crystallinity and morfology conditions. In this research, we have studied the relationship between SLS parameters and the desired PEEK morphology, roughness and crystallinity. All results showed that the temperature-control of the 3D printing method has a potential influence on the morphology layer by layer and it could be a potential to produce cranial implants, especially due to rough surface presented. However if uncontrolled the cooling temperature can reduce crystallinity probably impacting the 3D structure resistance.

Journal of neuroscience methods, Jan 24, 2018

Neuronavigation provides visual guidance of an instrument during procedures of neurological inter... more Neuronavigation provides visual guidance of an instrument during procedures of neurological interventions, and has been shown to be a valuable tool for accurately positioning transcranial magnetic stimulation (TMS) coils relative to an individual's anatomy. Despite the importance of neuronavigation, its high cost, low portability, and low availability of magnetic resonance imaging facilities limit its insertion in research and clinical environments. We have developed and validated the InVesalius Navigator as the first free, open-source software for image-guided navigated TMS, compatible with multiple tracking devices. A point-based, co-registration algorithm and a guiding interface were designed for tracking any instrument (e.g. TMS coils) relative to an individual's anatomy. Localization, precision errors, and repeatability were measured for two tracking devices during navigation in a phantom and in a simulated TMS study. Errors were measured in two commercial navigated TMS...

XXV Congresso de Iniciação Científica da Unicamp, 2017

Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que utiliza as ... more Este trabalho propõe um blueprint interdisciplinar para a biofabricação de órgãos que utiliza as ideias comuns de simulações-como métodos probabilísticos preditivos e cálculos de energia-aplicados a dois frameworks: o mecânico e o biológico. Em resumo, o mecânico utilizaria a análise de elementos finitos para observar comportamentos fluidodinâmicos como pressão hidrostática, elasticidade e fluxo de fluidos. Já o biológico utilizaria sistemas complexos de interação intra, inter e extracelular para analisar comportamentos como divisão celular, difusão e quimiotaxia das unidades básicas que compõem o órgão.

Procedia CIRP, 2016

Abstract The long-term success of implants depends on rapid healing and safe integration with bod... more Abstract The long-term success of implants depends on rapid healing and safe integration with body. In the case of orthopaedic and dental implants it was found that geometry and surface topography are crucial for short and long-term success of the implant, due to its effects in osseointegration. Properties of implant surfaces have been studied in the last decade in a concentrated effort to improve osseointegration process and implant success. Several researchers have proved that roughness of implant surface is related to healing time and integration between the implants and the bone, but the parameters on the surface creation are not fully controllable with current processes. In this work, computational algorithms are proposed for implant surface design in order to control the parameters required for this application. As a result it is presented an open-source software tool, called POMES - Porous and Modifications for Engineering Surfaces -, to design porous/roughness on top of surfaces in any geometry. Additionally, an example model was fabricated using POMES and additive manufacturing.

Independent Journal of Management & Production, 2015

Based on a case study, this paper presents a methodology to adopt ISO 9001 standards for organiza... more Based on a case study, this paper presents a methodology to adopt ISO 9001 standards for organizations, which make use of additive manufacturing to build products for medical use. Starting with a conceptual model, guidelines were identified to guide planning and operation of the management system, as well as its maintenance and improvement.

Journal of Cranio-Maxillofacial Surgery, 2008

Background: Selective laser sintering (SLS) and three-dimensional printing (3DPÔ) are rapid proto... more Background: Selective laser sintering (SLS) and three-dimensional printing (3DPÔ) are rapid prototyping (RP) techniques to fabricate prototypes from biomedical images. To be used in maxillofacial surgery, these models must accurately reproduce the craniofacial skeleton. Purpose: To analyze the capacity of SLS and 3DPÔ models to reproduce craniomaxillary anatomy and their dimensional error. Material: Dry skull, helical computed-tomography images, SLS and 3DPÔ prototypes, and electronic calliper. Methods: Tomographic images of a dry skull were manipulated with the InVesalius biomedical software. Prototypes were fabricated using SLS and 3DPÔ techniques. Ten linear measurements were made on the models and compared with corresponding dry skull measurements (criterion standard) carried out with an electronic calliper. Results: We observed a dimensional error of 2.10 and 2.67% for SLS and 3DPÔ models, respectively. The models satisfactorily reproduced anatomic details, except for thin bones, small foramina and acute bone projections. The SLS prototypes showed greater dimensional precision and reproduced craniomaxillary anatomy more accurately than the 3DPÔ models. Conclusion: Both SLS and 3DPÔ models provided acceptable precision and may be useful aids in most maxillofacial surgeries. Ó 2008 European Association for Cranio-Maxillofacial Surgery

Tissue spheroids (chondrospheres) are already used in clinical practice for treatment of cartilag... more Tissue spheroids (chondrospheres) are already used in clinical practice for treatment of cartilage defects. However, potential washing out of some non-attached tissue spheroids strongly suggests that preliminary attachment and spreading of tissue spheroids on electrospun matrices could potentially eliminate this undesirable effect. In order to estimate potential of using electrospun matrices as a carrier for tissue spheroids we study kinetics of tissue spheroids spreading on electrospun matrices.