José Andrade - Academia.edu (original) (raw)

Papers by José Andrade

PLOS ONE, 2017

The present study focuses on the application of scanning laser optical tomography (SLOT) for visu... more The present study focuses on the application of scanning laser optical tomography (SLOT) for visualization of anatomical structures inside the human cochlea ex vivo. SLOT is a laserbased highly efficient microscopy technique which allows for tomographic imaging of the internal structure of transparent specimens. Thus, in the field of otology this technique is best convenient for an ex vivo study of the inner ear anatomy. For this purpose, the preparation before imaging comprises decalcification, dehydration as well as optical clearing of the cochlea samples in toto. Here, we demonstrate results of SLOT imaging visualizing hard and soft tissue structures with an optical resolution of down to 15 μm using extinction and autofluorescence as contrast mechanisms. Furthermore, the internal structure can be analyzed nondestructively and quantitatively in detail by sectioning of the three-dimensional datasets. The method of X-ray Micro Computed Tomography (μCT) has been previously applied to explanted cochlea and is solely based on absorption contrast. An advantage of SLOT is that it uses visible light for image formation and thus provides a variety of contrast mechanisms known from other light microscopy techniques, such as fluorescence or scattering. We show that SLOT data is consistent with μCT anatomical data and provides additional information by using fluorescence. We demonstrate that SLOT is applicable for cochlea with metallic cochlear implants (CI) that would lead to significant artifacts in μCT imaging. In conclusion, the present study demonstrates the capability of SLOT for resolution visualization of cleared human cochleae ex vivo using multiple contrast mechanisms and lays the foundation for a broad variety of additional studies.

Revista Brasileira de Geomorfologia, 2020

Os sucessivos eventos de erosão, transporte e deposição de sedimentos que ocorrem nos rios propor... more Os sucessivos eventos de erosão, transporte e deposição de sedimentos que ocorrem nos rios proporcionam a formação e evolução de feições morfológicas no canal e na planície de inundação, com características morfológicas recorrentes a região onde está inserida. Ainda que haja estudos de rios localizados no clima semiárido, com padrão entrelaçado e anabranching, principalmente na Austrália, existe uma carência metodológica para rios semiáridos brasileiro. A produção acadêmica sobre barras e ilhas está concentrada nos ambientes fluviais localizados em clima tropical, subtropical e temperado, baseado nesse contexto, o trabalho tem como objetivo analisar as características morfológicas de barras e ilhas no rio Jaguaribe-CE, trecho que vai da passagem molhada da barragem das pedrinhas no Município de Limoeiro do Norte até a passagem molhada de Sucurujuba em Quixeré, com recorte temporal 2001 a 2016 (16 anos). Para isso, o trabalho foi estruturado a partir de uma lógica sistêmica, com et...

Applied Physics Letters, 2002

Acta Palaeontologica Polonica, 2011

A new specimen of Tupandactylus imperator, comprising an incomplete skull with associated lower j... more A new specimen of Tupandactylus imperator, comprising an incomplete skull with associated lower jaw, is described. The material is the best preserved specimen of this species known so far and provides new information on the anatomy of this pterodactyloid pterosaur, especially with respect to the morphology of the lower jaw, the first one formally described for the species. Also, the new specimen shows an extensive preservation of soft tissues such as the soft−tissue component of the headcrest, ramphoteca associated with the premaxillae and lower jaw, as well as probable pycnofibres. A phylogen− etic analysis was performed in order to test the relationships of the taxon within Tapejaridae. The results of the analysis support Tapejaridae, as well as monophyly of Tapejarinae and Thalassodrominae.

Arq Bras Cardiol, May 1, 1993

Journal of the International Association of Providers of AIDS Care

Published data addressing the effectiveness of darunavir-ritonavir (DRV/r)-based therapy for mult... more Published data addressing the effectiveness of darunavir-ritonavir (DRV/r)-based therapy for multiexperienced patients in developing countries are scarce. This study evaluated the 48-week virologic and immunologic effectiveness of salvage therapy based on DRV/r for the treatment of multidrug-experienced HIV-1-infected adults in Brazil. A multicenter retrospective cohort study was carried out with multidrug-experienced adults who were on a failing antiretroviral therapy and started a DRV/r-based salvage therapy between 2008 and 2010. The primary effectiveness end point was the proportion of patients with virologic success (plasma HIV-1 RNA <50 copies/mL at week 48). At 48 weeks, 73% of the patients had HIV-RNA <50 copies/mL and a mean increase of 108 CD4 cells/mm(3). Higher baseline viral load, lower baseline CD4 count, younger age, and 3 or more DRV/r-associated resistance mutations were significantly predictive of virologic failure. Concomitant use of raltegravir was strongly...

Trees, 2005

Water uptake and transport were studied in eight liana species in a seasonally dry tropical fores... more Water uptake and transport were studied in eight liana species in a seasonally dry tropical forest on Barro Colorado Island, Panama. Stable hydrogen isotope composition (δD) of xylem and soil water, soil volumetric water content (θ v ), and basal sap flow were measured during the 1997 and 1998 dry seasons. Sap flow of several neighboring trees was measured to assess differences between lianas and trees in magnitudes and patterns of daily sap flow. Little seasonal change in θ v was observed at 90-120 cm depth in both years. Mean soil water δD during the dry season was −19‰ at 0-30 cm, −34‰ at 30-60 cm, and −50‰ at 90-120 cm. Average values of xylem δD among the liana species ranged from -28‰ to -44‰ during the middle of the dry season, suggesting that water uptake was restricted to intermediate soil layers (30-60 cm). By the end of the dry season, all species exhibited more negative xylem δD values (-41‰ to -62‰ ), suggesting that they shifted to deeper water sources. Maximum sap flux density in cooccurring lianas and trees were comparable at similar stem diameter (DBH). Furthermore, lianas and trees conformed to the same linear relationship between daily sap flow and DBH. Our observations that lianas tap shallow sources of soil water at the beginning of the dry season and that sap flow is similar in lianas and trees of equivalent stem diameter do not support the common assumptions that lianas rely primarily on deep soil water and that they have higher rates of sap flow than co-occurring trees of similar stem size.

Plant Ecology, 2005

In the tropical dry forest of Dzibilchaltu´n, Yucatan, Mexico, light microhabitats, tissue acidit... more In the tropical dry forest of Dzibilchaltu´n, Yucatan, Mexico, light microhabitats, tissue acidity changes, chlorophyll fluorescence and growth were investigated for the epiphytic bromeliad Tillandsia brachycaulos Schltdl. Most individuals occurred in sites between 20 and 60% of the height of the tree, and directly on the main trunk or branches closed to the main trunk. During the dry season, individuals received about nine times more photon flux density (PFD) than during the rainy season. Individuals that occurred under 30-59% of the daily ambient PFD showed greater leaf length increase and monthly leaf production, and produced more flowers than individuals in the brighter (>60% of ambient PFD) and the darker (11-29% of ambient PFD) light microhabitats. Well-watered plants acclimated to deep shade (6% of ambient PFD) showed values of tissue acidity similar to plants under higher light treatments. Well-watered plants under 60% of daily ambient PFD showed low values of maximum quantum efficiency at midday during most of the year but showed similar values of tissue acidity than plants under 6 and 30% of ambient PFD. Leaf temperatures of plants in low sites within the canopy and on the forest floor were significantly higher than the air during about 1 h, indicating that those plants could not dissipate the excess of heat. Individuals located in the most shaded microhabitats could also receive less amount of water from rainfall and dew. Therefore, it would be less damaging for this epiphytic bromeliad to occur in the most exposed microhabitats than in the most shaded microhabitats in this tropical dry forest.

International Journal of Plant Sciences, 2006

(2006) Cervera et al. International Journal of Plant Sciences. Read by researchers in: 50% Biolog... more (2006) Cervera et al. International Journal of Plant Sciences. Read by researchers in: 50% Biological Sciences, 50% Environmental Sciences. Mammillaria gaumeri is a rare cactus endemic to northern Yucatan that has a low rate of seedling establishment. We evaluated the effect ...

Biotropica, 2007

Mammillaria gaumeri, an endemic cactus from Yucatan, is threatened due to human-mediated habitat ... more Mammillaria gaumeri, an endemic cactus from Yucatan, is threatened due to human-mediated habitat fragmentation but knowledge regarding factors that would inform management plans is limited, including information on optimal microhabitats and growth. We studied ...

Acta Tropica, 2013

The non-flooded upland rainforest fragment in the Federal University of Amazonas Campus is consid... more The non-flooded upland rainforest fragment in the Federal University of Amazonas Campus is considered one of the world's largest urban tropical woodland areas and Brazil's second largest one in an urban setting. It is located in the city of Manaus, State of Amazonas at 03 • 04 34 S, 59 • 57 30 W, in an area covering nearly 800 hectares. Forty-one (41) sand fly species belonging to genus Lutzomyia were found attaining a total of 4662 specimens collected. Lutzomyia umbratilis was the dominant species at all heights, followed by Lutzomyia anduzei and Lutzomyia claustrei. The fauna alpha diversity index showed to be 6.4, which is not much lower than that reported for areas of continuous forest in this Amazonian region. This data provides additional evidence on Phlebotomine sand flies found to transmit Leishmania and other trypanosomatids to humans and other animals circulating in this area. This is the first study being reported on sand flies collected in an urban rainforest fragment in Amazonia.

Arq Bras Cardiol, Aug 1, 2000

Arq Bras Cardiol, Aug 1, 1998

Alcohol and Alcoholism

ABSTRACT

Ambiente & sociedade, 2001

Revista de Administração Contemporânea, 2001

There are several studies related to the explanation of the economic dynamism of Brazilian agroin... more There are several studies related to the explanation of the economic dynamism of Brazilian agroindustrial chain of eucalyptus market-pulp, based on quite different theoretical perspectives: neoschumpeterian technological progress; planned public politics; lobbies of private interests. However, there is still a domain which remains underestimated by researchers: that related to the relationship builded between the State and the economic agents as a process of exchanging interests, where are negotiated important arrangements for the construction of a political-institutional ambience favorable to the shaping of new techno-economic paradigms. Analysing the emergence and establishment of eucaplyptus pattern in Aracruz Celulose S.A., in the period 1965-1992, the authors argue that this process is the historic result of interactions between corporate strategies and its political-institutional milieu, made up as a movement of political orchestration among governamental agencies and self-organized private interests. In doing so, the authors constructed an analytic tool resulting from the articulation of the neoschumpeterian dimension of technological innovation and the neo-institutionalist economical approach, focused on neocorporatist forms of political interchange.

Neuroscience Letters, 1999

We have examined if age-related deterioration of spatial memory and cholinergic innervation of th... more We have examined if age-related deterioration of spatial memory and cholinergic innervation of the dentate gyrus is gender-speci®c. Aging progressively affected the performance of male and female rats in place discrimination version of the water maze task. On repeated acquisition task, only old males, but not old females, were signi®cantly impaired relative to young and adult animals of both sexes. In parallel, we found that the age-associated reduction of the density of cholinergic ®bers in the dentate gyrus was signi®cantly more profound in old males than in age-matched females. These results suggest that, although male and female rats have an identical pattern of reference memory decline, impairment of the working memory and deterioration of the hippocampal cholinergic system are slower to develop in females than in males. q

Journal of the American Society of Echocardiography, 2007

The objective was to analyze the diagnostic value of the echocardiographic methods used for quant... more The objective was to analyze the diagnostic value of the echocardiographic methods used for quantification of mitral regurgitation (MR) in patients with mitral valve prolapse (MVP) or rheumatic heart disease (RHD). Methods: The study included 50 patients with MR (mean age of 46.1 years; 35 women), 27 (54%) with RHD and 23 (46%) with MVP. Quantification of the mitral valve regurgitation was obtained by regurgitant orifice area (ROA) and regurgitant volume (RV) by the flow convergence region (FCR) and two-dimensional Doppler echocardiographic methods, regurgitant fraction, jet area (JA), jet area/left atrial area ratio (JA/LAA), and vena contracta (VC). Patients were clinically followed to identify cardiovascular events. Data were analyzed by Pearson, kappa, and receiver operator charac-teristic curve tests; significance was defined as a P value less than .05. Results: The correlation between the two methods for ROA and RV were r ‫؍‬ 0.79 and r ‫؍‬ 0.80, respectively, and between these parameters and regurgitant fraction, VC, JA, and JA/LAA varied from r ‫؍‬ 0.54 to r ‫؍‬ 0.94 (P lt; .05); the agreement varied from ‫؍‬ 0.19 to ‫؍‬ 0.83. The highest accuracy to identify patients with clinically significant MR (events at follow-up) was 96% for ROA by FCR, 94% for VC, 86% for RV by FCR, and 86% for JA. No method showed a significant difference between MVP and RHD. Conclusions: The methods analyzed had significant correlation and good agreement. ROA by FCR and VC had the best performance to identify severe MR; no significant difference between MVP and RHD was observed.