Jose Luis Ceballos - Academia.edu (original) (raw)
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Papers by Jose Luis Ceballos
Journal of Cranio-maxillofacial Surgery, 2011
Tumours of the temporomandibular joint (TMJ) often mimic common conditions of the TMJ, such as TM... more Tumours of the temporomandibular joint (TMJ) often mimic common conditions of the TMJ, such as TMJ dysfunction syndrome, leading to a delay in the diagnosis. Chondrosarcoma of the TMJ is a rare tumour, with only 18 cases described in the literature. The initial surgical attempt at removal is of important, as aggressive excision offers the best chance for successful treatment. Chondrosarcoma present at the surgical resection margins has a poor prognosis. We present a case of chondrosarcoma of the right TMJ. In our case, combined diagnostic techniques consisting of a panoramic radiograph, computed tomography (CT) and magnetic resonance imaging (MRI) made an accurate preoperative assessment possible and significantly influenced the treatment provided.
International Journal of Oral and Maxillofacial Surgery, 2010
Lipomas are common benign neoplasms affecting many adipose tissuecontaining organs of the body, i... more Lipomas are common benign neoplasms affecting many adipose tissuecontaining organs of the body, including bone. Central lesions in bone account for less than 1% of all lipomas. In the literature, intraosseous lipomas have been reported in various bones such as the frontal and parietal bones, ribs, ulna, phalanges of hand and foot, femoral neck, fibula and calcaneum. No preference has been described for gender or race. As far as the authors know, there have been no documented cases of intraosseous lipoma involving the temporomandibular joint. This report describes a rare case of mandibular intraosseous lipoma in the left condylar area associated with temporomandibular dysfunction.
Tetrahedron-asymmetry, 2011
The one-pot three-component reaction of 2-formylbenzoic acid with (S)-and (R)-methylbenzylamine a... more The one-pot three-component reaction of 2-formylbenzoic acid with (S)-and (R)-methylbenzylamine and dimethyl phosphite (Kabachnik-Fields reaction) proceeded in short reaction times under solvent and catalyst free-conditions to afford the corresponding (3R,1 0 S)-and (3S,1 0 R)-isoindolin-1-one-3-phosphonates 3, respectively, in good yield and with high diastereoselectivity (95:5 dr). The use of a solvent decreases the diastereoselectivity and slows the reaction rate. The reaction rate was also influenced by CO 2 H functionality through protonation of the imine intermediate. The absolute configuration at the new stereogenic center was determined by X-ray crystal analysis, and a mechanism was proposed to explain the high diastereoselectivity.
Oncologist, 2007
Background. 5-HT 3 -receptor antagonists are one of the mainstays of antiemetic treatment, and th... more Background. 5-HT 3 -receptor antagonists are one of the mainstays of antiemetic treatment, and they are administered either i.v. or orally. Nevertheless, sometimes neither administration route is feasible, such as in patients unable to admit oral intake managed in an outpatient setting. Our objective was to evaluate the bioavailability of s.c. granisetron.
Journal of Cranio-maxillofacial Surgery, 2011
Tumours of the temporomandibular joint (TMJ) often mimic common conditions of the TMJ, such as TM... more Tumours of the temporomandibular joint (TMJ) often mimic common conditions of the TMJ, such as TMJ dysfunction syndrome, leading to a delay in the diagnosis. Chondrosarcoma of the TMJ is a rare tumour, with only 18 cases described in the literature. The initial surgical attempt at removal is of important, as aggressive excision offers the best chance for successful treatment. Chondrosarcoma present at the surgical resection margins has a poor prognosis. We present a case of chondrosarcoma of the right TMJ. In our case, combined diagnostic techniques consisting of a panoramic radiograph, computed tomography (CT) and magnetic resonance imaging (MRI) made an accurate preoperative assessment possible and significantly influenced the treatment provided.
International Journal of Oral and Maxillofacial Surgery, 2010
Lipomas are common benign neoplasms affecting many adipose tissuecontaining organs of the body, i... more Lipomas are common benign neoplasms affecting many adipose tissuecontaining organs of the body, including bone. Central lesions in bone account for less than 1% of all lipomas. In the literature, intraosseous lipomas have been reported in various bones such as the frontal and parietal bones, ribs, ulna, phalanges of hand and foot, femoral neck, fibula and calcaneum. No preference has been described for gender or race. As far as the authors know, there have been no documented cases of intraosseous lipoma involving the temporomandibular joint. This report describes a rare case of mandibular intraosseous lipoma in the left condylar area associated with temporomandibular dysfunction.
Tetrahedron-asymmetry, 2011
The one-pot three-component reaction of 2-formylbenzoic acid with (S)-and (R)-methylbenzylamine a... more The one-pot three-component reaction of 2-formylbenzoic acid with (S)-and (R)-methylbenzylamine and dimethyl phosphite (Kabachnik-Fields reaction) proceeded in short reaction times under solvent and catalyst free-conditions to afford the corresponding (3R,1 0 S)-and (3S,1 0 R)-isoindolin-1-one-3-phosphonates 3, respectively, in good yield and with high diastereoselectivity (95:5 dr). The use of a solvent decreases the diastereoselectivity and slows the reaction rate. The reaction rate was also influenced by CO 2 H functionality through protonation of the imine intermediate. The absolute configuration at the new stereogenic center was determined by X-ray crystal analysis, and a mechanism was proposed to explain the high diastereoselectivity.
Oncologist, 2007
Background. 5-HT 3 -receptor antagonists are one of the mainstays of antiemetic treatment, and th... more Background. 5-HT 3 -receptor antagonists are one of the mainstays of antiemetic treatment, and they are administered either i.v. or orally. Nevertheless, sometimes neither administration route is feasible, such as in patients unable to admit oral intake managed in an outpatient setting. Our objective was to evaluate the bioavailability of s.c. granisetron.