Joshua Schoenfeld - Academia.edu (original) (raw)
Uploads
Papers by Joshua Schoenfeld
Free Radical Biology and Medicine, 2015
Free Radical Biology and Medicine, 2015
Free Radical Biology and Medicine, 2015
Free Radical Biology and Medicine, 2014
Observers' ratings of communal coping (cooperative problem solving) based on interviews with ... more Observers' ratings of communal coping (cooperative problem solving) based on interviews with 20 heart-failure patients and their spouses predicted the patient's survival 4 years later. Although the measure was not highly stable across patient-spouse roles and two stressful situations, a communal orientation by women (both patients and spouses) had prognostic significance in this exploratory study. A growing body of empirical research highlights the key role of close relationships in successful coping with chronic heart disease. In a recent study of congestive heart failure (CHF) patients and their spouses, a composite measure of marital quality predicted 4-year survival independent of illness severity, especially for female patients (Coyne, Rohrbaugh et al., 2001; Rohrbaugh, Shoham et al., in press). The marital component predicting best was frequency of useful illness discussions, a variable reminiscent of what Lyons et al. (1998) call "communal coping" (CC).
Free Radical Biology and Medicine, 2014
Development (Cambridge, England), 2014
Scribble (Scrib) module proteins are major regulators of cell polarity, but how they influence me... more Scribble (Scrib) module proteins are major regulators of cell polarity, but how they influence membrane traffic is not known. Endocytosis is also a key regulator of polarity through roles that remain unclear. Here we link Scrib to a specific arm of the endocytic trafficking system. Drosophila mutants that block AP-2-dependent endocytosis share many phenotypes with Scrib module mutants, but Scrib module mutants show intact internalization and endolysosomal transport. However, defective traffic of retromer pathway cargo is seen, and retromer components show strong genetic interactions with the Scrib module. The Scrib module is required for proper retromer localization to endosomes and promotes appropriate cargo sorting into the retromer pathway via both aPKC-dependent and -independent mechanisms. We propose that the Scrib module regulates epithelial polarity by influencing endocytic itineraries of Crumbs and other retromer-dependent cargo.
For a multi-site clinical trial testing the efficacy of Szapocznik et al.'s Brief Strategic ... more For a multi-site clinical trial testing the efficacy of Szapocznik et al.'s Brief Strategic Family Therapy (BSFT) in community settings, we developed a Views of Adolescent Drug Abuse Q-sort (VADA-Q) to study therapists' theoretical orientation. Q-methodology helps define how the BSFT model differs from other views of adolescent drug abuse and provides a useful tool for research and therapist training.
Free Radical Biology and Medicine, 2015
Free Radical Biology and Medicine, 2015
Free Radical Biology and Medicine, 2015
Free Radical Biology and Medicine, 2014
Observers' ratings of communal coping (cooperative problem solving) based on interviews with ... more Observers' ratings of communal coping (cooperative problem solving) based on interviews with 20 heart-failure patients and their spouses predicted the patient's survival 4 years later. Although the measure was not highly stable across patient-spouse roles and two stressful situations, a communal orientation by women (both patients and spouses) had prognostic significance in this exploratory study. A growing body of empirical research highlights the key role of close relationships in successful coping with chronic heart disease. In a recent study of congestive heart failure (CHF) patients and their spouses, a composite measure of marital quality predicted 4-year survival independent of illness severity, especially for female patients (Coyne, Rohrbaugh et al., 2001; Rohrbaugh, Shoham et al., in press). The marital component predicting best was frequency of useful illness discussions, a variable reminiscent of what Lyons et al. (1998) call "communal coping" (CC).
Free Radical Biology and Medicine, 2014
Development (Cambridge, England), 2014
Scribble (Scrib) module proteins are major regulators of cell polarity, but how they influence me... more Scribble (Scrib) module proteins are major regulators of cell polarity, but how they influence membrane traffic is not known. Endocytosis is also a key regulator of polarity through roles that remain unclear. Here we link Scrib to a specific arm of the endocytic trafficking system. Drosophila mutants that block AP-2-dependent endocytosis share many phenotypes with Scrib module mutants, but Scrib module mutants show intact internalization and endolysosomal transport. However, defective traffic of retromer pathway cargo is seen, and retromer components show strong genetic interactions with the Scrib module. The Scrib module is required for proper retromer localization to endosomes and promotes appropriate cargo sorting into the retromer pathway via both aPKC-dependent and -independent mechanisms. We propose that the Scrib module regulates epithelial polarity by influencing endocytic itineraries of Crumbs and other retromer-dependent cargo.
For a multi-site clinical trial testing the efficacy of Szapocznik et al.'s Brief Strategic ... more For a multi-site clinical trial testing the efficacy of Szapocznik et al.'s Brief Strategic Family Therapy (BSFT) in community settings, we developed a Views of Adolescent Drug Abuse Q-sort (VADA-Q) to study therapists' theoretical orientation. Q-methodology helps define how the BSFT model differs from other views of adolescent drug abuse and provides a useful tool for research and therapist training.