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Papers by Juan Jiménez

Research paper thumbnail of La imagen del Cristo de la Salud del convento franciscano de Estepa

Archivo ibero-americano, 2018

La imagen deL Cristo de la salud deL convento franciscano de estepa. nota histórico-artística y e... more La imagen deL Cristo de la salud deL convento franciscano de estepa. nota histórico-artística y estado actuaL the image of the Cristo de la salud at the franciscan friary of stepa (spain). historicaL and artistic report and current conservation status

Research paper thumbnail of Content Alerts

This article cites 53 articles, 17 of which can be accessed free

Research paper thumbnail of Simultaneous phenotypic and genetic characterization of single circulating tumor cells from colon cancer patients

Histology and histopathology, Nov 1, 2013

Since circulating tumor cells (CTCs) have metastatic potential, their genetic and phenotypic char... more Since circulating tumor cells (CTCs) have metastatic potential, their genetic and phenotypic characteristics could provide crucial information to establish the most effective therapy. We assessed the clinical utility of a methodology that allows the simultaneous analysis of CTC phenotype and genotype in colon cancer patients and, in addition, whether this methodology could provide complementary information to that obtained by the primary tumor biopsy. Thirty-three non-metastatic (stages 0-III) colon cancer patients and 9 healthy donor samples were evaluated. All peripheral blood samples (10 ml) were analyzed by cytokeratin immunomagnetic enrichment. Eight samples were analyzed by immunocytochemistry and 25 samples were analyzed by FICTION technique for simultaneous cytokeratin expression and chromosome 17 and ERBB2 gene status. A further study was carried out in one patient who showed CTC heterogeneity in chromosomal abnormalities. We analyzed HER2 protein expression on CTCs and FIS...

Research paper thumbnail of The effect of proton and gamma radiation on different types of temperature sensors

Radiation and Its …, 2009

In a study performed to test the effects of proton and gamma radiation on different temperature s... more In a study performed to test the effects of proton and gamma radiation on different temperature sensors, Pt RTDs and thermocouples show a negligible sensitivity. On the other hand, IC-based temperature sensors modify significantly their behavior. AD590 sensors ...

Research paper thumbnail of Compromise between seabird enjoyment and disturbance: the role of observed and observers

Environmental …, 2008

Natural areas are increasingly visited by people, and urban human visitors expect to watch wildli... more Natural areas are increasingly visited by people, and urban human visitors expect to watch wildlife as close as possible, but this may have associated disturbance costs. Here, effects of number of visitors and bird density on flight initiation distance (FID) as a proxy of disturbance vulnerability were evaluated in the large ground-nesting yellow-legged gull, Larus michahellis. Mean FID decreased with increasing number of visitors and with increasing gull densities, suggesting that (1) ground-nesting gulls habituate to massive human presence, while retaining their antipredatory mechanisms, and (2) dense groups of gulls were more reluctant to fly away. This density effect may be due to the increased risk of clutch predation by conspecifics at high densities and, if so, FID is a reliable metric of disturbance vulnerability in groundnesting gulls. In conclusion, setback distances are specific to local populations and it is unnecessary to ban or restrict human visits to ground-nesting gull colonies; redistributing visits, taking into account both the number of visitors and gull density, is preferable.

Research paper thumbnail of La imagen del Cristo de la Salud del convento franciscano de Estepa

Archivo ibero-americano, 2018

La imagen deL Cristo de la salud deL convento franciscano de estepa. nota histórico-artística y e... more La imagen deL Cristo de la salud deL convento franciscano de estepa. nota histórico-artística y estado actuaL the image of the Cristo de la salud at the franciscan friary of stepa (spain). historicaL and artistic report and current conservation status

Research paper thumbnail of Content Alerts

This article cites 53 articles, 17 of which can be accessed free

Research paper thumbnail of Simultaneous phenotypic and genetic characterization of single circulating tumor cells from colon cancer patients

Histology and histopathology, Nov 1, 2013

Since circulating tumor cells (CTCs) have metastatic potential, their genetic and phenotypic char... more Since circulating tumor cells (CTCs) have metastatic potential, their genetic and phenotypic characteristics could provide crucial information to establish the most effective therapy. We assessed the clinical utility of a methodology that allows the simultaneous analysis of CTC phenotype and genotype in colon cancer patients and, in addition, whether this methodology could provide complementary information to that obtained by the primary tumor biopsy. Thirty-three non-metastatic (stages 0-III) colon cancer patients and 9 healthy donor samples were evaluated. All peripheral blood samples (10 ml) were analyzed by cytokeratin immunomagnetic enrichment. Eight samples were analyzed by immunocytochemistry and 25 samples were analyzed by FICTION technique for simultaneous cytokeratin expression and chromosome 17 and ERBB2 gene status. A further study was carried out in one patient who showed CTC heterogeneity in chromosomal abnormalities. We analyzed HER2 protein expression on CTCs and FIS...

Research paper thumbnail of The effect of proton and gamma radiation on different types of temperature sensors

Radiation and Its …, 2009

In a study performed to test the effects of proton and gamma radiation on different temperature s... more In a study performed to test the effects of proton and gamma radiation on different temperature sensors, Pt RTDs and thermocouples show a negligible sensitivity. On the other hand, IC-based temperature sensors modify significantly their behavior. AD590 sensors ...

Research paper thumbnail of Compromise between seabird enjoyment and disturbance: the role of observed and observers

Environmental …, 2008

Natural areas are increasingly visited by people, and urban human visitors expect to watch wildli... more Natural areas are increasingly visited by people, and urban human visitors expect to watch wildlife as close as possible, but this may have associated disturbance costs. Here, effects of number of visitors and bird density on flight initiation distance (FID) as a proxy of disturbance vulnerability were evaluated in the large ground-nesting yellow-legged gull, Larus michahellis. Mean FID decreased with increasing number of visitors and with increasing gull densities, suggesting that (1) ground-nesting gulls habituate to massive human presence, while retaining their antipredatory mechanisms, and (2) dense groups of gulls were more reluctant to fly away. This density effect may be due to the increased risk of clutch predation by conspecifics at high densities and, if so, FID is a reliable metric of disturbance vulnerability in groundnesting gulls. In conclusion, setback distances are specific to local populations and it is unnecessary to ban or restrict human visits to ground-nesting gull colonies; redistributing visits, taking into account both the number of visitors and gull density, is preferable.

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