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Papers by Juan Troyano

Research paper thumbnail of Tumor de Brenner maligno: caso clínico

Revista chilena de obstetricia y ginecología, 2012

El tumor de Brenner es una neoplasia rara, que representa el 1-2 % de las neoplasias de ovario. L... more El tumor de Brenner es una neoplasia rara, que representa el 1-2 % de las neoplasias de ovario. La mayoría son benignas, pero existe un pequeño porcentaje de casos de tumor de Brenner maligno, entre ellos el caso que se presenta. Se trata de una mujer de 41 años que presentó una tumoración ovárica cuyo resultado anatomopatológico fue de carcinoma pobremente diferenciado, con asociación de tumor tipo Brenner maligno. A pesar de ser diagnosticado en estadio precoz, este caso destaca por su mal pronóstico. PALABRAS CLAVE: Tumor de Brenner, cáncer de ovario, células transicionales, núcleos en "grano de café" SUMMARY Brenner tumor is a rare neoplasia, accounting for 1-2% of ovarian cancer. Most of them are benign, but there are a small percentage of malignant Brenner tumors, including the case presented. This is a 41-yearold woman who presented an ovarian tumor. Definitive histological result showed a poorly differentiated carcinoma, with association of malignant Brenner tumor. Despite being diagnosed in early stages, this case stands out for its poor prognosis.

Research paper thumbnail of Diagnóstico ecográfico prenatal y resultados neonatales de la malformación adenomatoidea quística pulmonar

Revista chilena de pediatría, 2018

Introduction: Congenital cystic adenomatoid malformation (CCAM) is a rare congenital lung disease... more Introduction: Congenital cystic adenomatoid malformation (CCAM) is a rare congenital lung disease, and in the most of cases, prenatal diagnosis is feasible. There are discrepancies regarding prenatal management and postpartum treatment. Objective: To analyze prenatally diagnosed CCAM in our hospitals, in order to evaluate ultrasound findings with fetal and postnatal evolution. Patients and Method: Retrospective study of all cases diagnosed prenatally by ultrasound between 2005 and 2016 in two reference hospitals. The ultrasounds were performed using high-resolution ultrasound scanners, Toshiba Xario and Voluson 730 Expert Pro, with follow-up from diagnosis to delivery. The variables analyzed included gestational age at diagnosis, the characteristics of the lung lesion, associated malformations, cytogenetic study, the evolution of pregnancy, type of delivery, presence of respiratory distress, need for complementary imaging tests, pediatric clinical course, and necessary postnatal treatments. It was considered a resolution the total disappearance of the lesion in the prenatal ultrasound or that the postnatal chest X-ray showed no lesion. Results: 17 cases were prenatally diagnosed. The evolution ranges from the prenatal resolution of the lesion to the persistence after birth. Three patients voluntarily decided to have an abortion due to ultrasound findings of poor prognosis. Of the fourteen remaining cases there were no cases of fetal or neonatal deaths, one case required surgery after birth and four patients had mild symptoms during the first year of life. One case of false negative with neonatal death has been reported which necropsy reported as CCAM type 0. Conclusions: This pulmonary malformation presents good prognosis, excluding cases with fetal hydrops. Two-dimensional ultrasound is usually enough for diagnosis and follow-up. Computed tomography is the technique of choice to confirm the resolution of lesions after birth. Surgical treatment is preferable over conservative management, although it is unknown if the potential complications of this disease, even when asymptomatic, justify surgical morbidity.

Research paper thumbnail of Can 3-dimensional Ultrasound Change Gynecological Ultrasonographic Examination?

Donald School Journal of Ultrasound in Obstetrics and Gynecology, 2009

Objective To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ult... more Objective To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ultrasonography and whether it provides additional advantages in gynecologic diagnosis. Material and methods We performed a prospective study in 46 women who underwent 2D and 3D transvaginal scans successively. Three 3D volumes (uterus and each ovary) were acquired and evaluated 4 months later on a personal computer. We compared 2D and 3D scans in relation to sonographic diagnosis and biometry and the time spent. Results There was complete agreement between 2D and 3D techniques for sonographic diagnosis (31 normal exams, 16 adnexal cysts and seven myomas), except for the visualization and measurement of the uterine cervix. The mean time for 2D scans was 3.29 ± 1.32 minutes and was 2.96 ± 0.58 minutes for 3D examination (P = 0.076). The time required to acquire 3D volumes was only 1 hour, freeing 1 hour and 32 minutes for the performance of new scans. Conclusions Transvaginal 3D ultrasonogra...

Research paper thumbnail of The labor induction: integrated clinical and sonographic variables that predict the outcome

Journal of Perinatology, 2007

Objective: To analyze the clinical and sonographic variables that predicts the success of labor i... more Objective: To analyze the clinical and sonographic variables that predicts the success of labor induction. Study design: We studied the Bishop score, cervical length and parity in 196 pregnant women in the prediction of successful vaginal delivery within 24 h of induction. Logistic regression and segmentation analysis were performed. Results: Cervical length (odds ratio (OR) 1.089, P<0.001), Bishop score (OR 0.751, P ¼ 0.001) and parity (OR 4.7, P<0.001) predict the success of labor induction. In a global analysis of the variables studied, the best statistic sequence that predicts the labor induction was found when we introduced parity in the first place. The success of labor induction in nulliparous was 50.8 and 83.3% in multiparous women (P ¼ 0.0001). Conclusions: Cervical length, Bishop score and parity, integrated in a flow chart, provide independent prediction of vaginal delivery within 24 h of induction.

Research paper thumbnail of Hidrops Fetal Como Manifestación Ecográfica De Una Enfermedad Familiar: Incontinentia Pigmenti (Síndrome De Bloch-Sulzberger)

Revista chilena de obstetricia y ginecología, 2010

Research paper thumbnail of Sonography of pelvic infection

The Ultrasound Review of Obstetrics & Gynecology, 2005

We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute P... more We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute PID (acute salpingitis) begins with a challenge for the doctor, due to the little sensibility of the clinic's criteria. The accumulation of pus inside the fallopian tube gives a location for the tubaric abscess or pyosalpinx, whose characteristic signal is the presence of purulent material in considerable quantities and is visible by means of a sonograph inside the tubal light. We refer a series of characteristic sings that advise us.

Research paper thumbnail of Sonography of pelvic infection

The Ultrasound Review of Obstetrics & Gynecology, 2005

We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute P... more We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute PID (acute salpingitis) begins with a challenge for the doctor, due to the little sensibility of the clinic's criteria. The accumulation of pus inside the fallopian tube gives a location for the tubaric abscess or pyosalpinx, whose characteristic signal is the presence of purulent material in considerable quantities and is visible by means of a sonograph inside the tubal light. We refer a series of characteristic sings that advise us.

Research paper thumbnail of Determinants of organochlorine levels detectable in the amniotic fluid of women from Tenerife Island (Canary Islands, Spain)

Environmental Research, 2009

Organochlorines (OCs) tend to accumulate in human tissues and can be measured in amniotic fluid (... more Organochlorines (OCs) tend to accumulate in human tissues and can be measured in amniotic fluid (AF). The detection of OCs in AF samples reflects intrauterine exposure of human beings to these persistent organic pollutants. The present study was performed to evaluate the level of contamination of AF by OCs in 100 pregnant women from Tenerife Island (Canary Islands, Spain). Gas chromatography/mass spectrometry (GC/MS) was used to identify and quantify the analytes, including 7 polychlorobiphenyl (PCB) congeners and 18 OC pesticides and metabolites. The majority of the AF samples (67%) showed some detectable OC-residue, hexachlorobenzene (HCB) being the most frequently detected compound (66% of the samples) and at the highest concentration (median 0.023 ng/ml). Lindane was also detected in 28% of the samples. Inverse associations were found between previous lactation and hexachlorocyclohexane isomers (HCH) and cyclodienes in the group of younger women (p ¼ 0.037 and p ¼ 0.027, respectively). Unexpectedly, serum values of HCB (r ¼ À0.414; p ¼ 0.04), g-HCH (r ¼ À0.294; p ¼ 0.035), and P OCs (r ¼ À0.350; p ¼ 0.014) were negatively related to age. Even more, women with detectable levels of HCH isomers were younger (33.974.9 years) than women with undetectable levels of them (36.174.9 years; p ¼ 0.035). We conclude that approximately one in two fetuses in the Canary Islands is exposed to OCs in utero, and that, therefore, the exposure of young women from these Islands to some HCH isomers persists nowadays. Because prenatal exposure to these chemicals may be a causative factor in adverse health trends, further studies are required to enhance preventive measures.

Research paper thumbnail of Luis T Mercé et al 6 Can 3-dimensional Ultrasound Change

Objective: To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ul... more Objective: To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ultrasonography and whether it provides additional advantages in gynecologic diagnosis. Material and methods: We performed a prospective study in 46 women who underwent 2D and 3D transvaginal scans successively. Three 3D volumes (uterus and each ovary) were acquired and evaluated 4 months later on a personal computer. We compared 2D and 3D scans in relation to sonographic diagnosis and biometry and the time spent. Results: There was complete agreement between 2D and 3D techniques for sonographic diagnosis (31 normal exams, 16 adnexal cysts and seven myomas), except for the visualization and measurement of the uterine cervix. The mean time for 2D scans was 3.29 ± 1.32 minutes and was 2.96 ± 0.58 minutes for 3D examination (P = 0.076). The time required to acquire 3D volumes was only 1 hour, freeing 1 hour and 32 minutes for the performance of new scans. Conclusions: Transvaginal 3D ultrason...

Research paper thumbnail of 50 th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida Cambridge , UK 30 August – 2 September 2006

The 50 Annual Scientific Meeting of the Society for Research into Hydrocephalus and Spina Bifida ... more The 50 Annual Scientific Meeting of the Society for Research into Hydrocephalus and Spina Bifida took place in the historic surroundings of Queens’ College in Cambridge, England. Delegates were warmly welcomed by Professor John Pickard and his organising team from the Department of Academic Neurosurgery, and we are especially indebted to Dr. Hugh Richards for his tireless work to make this conference a success. A feature of the 50 anniversary meeting was a presentation from archivists Ewen Mackinnon and Leonie Holgate, featuring documents and photographs illustrating the society’s activities over the past 50 years. We were also happy to welcome a large delegation from Association for Spina Bifida and Hydrocephalus, who helped with the administration of the conference as well as making a contribution to proceedings. Their chief executive, Andrew Russell, gave a talk outlining his tireless efforts in the cause of flour fortification with folic acid. Cambridge is an ancient and beautif...

Research paper thumbnail of �Puede la ecograf�a tridimensional cambiar la exploraci�n ecogr�fica ginecol�gica en nuestro medio?

Research paper thumbnail of Ultrasound-guided fetal invasive procedures

Textbook of Perinatal Medicine, Second Edition, 2006

Research paper thumbnail of Ultrasonographic signs of poor pregnancy outcome

The Ultrasound Review of Obstetrics & Gynecology, 2005

The frequency of spontaneous abortion, when it is considered from its very beginning, along with ... more The frequency of spontaneous abortion, when it is considered from its very beginning, along with the theoretical knowledge of the causes of the abortion, should provide a perspective to the obstetrician that, performing a sonographic exploration finds discoveries that cannot correspond to those characterizing a normal pregnancy. The precocity of the realization of sonographic explorations in the pregnancy will allow diagnosis of many more cases of spontaneous interruptions of the development of pregnancy. New sonographic imaging techniques including threedimensional (3D) sonography can provide additional information regarding the presence of structural anomalies via 3D volume acquisition, like craniofacial deformities, clefts, neural tube defects, abdominal wall defects, and caudal regression syndrome. It may give further details regarding the timing of embryonic/ fetal demise in early pregnancy. Sufficient informational value is regularly obtained in cases having a crown-rump length >8 mm.

Research paper thumbnail of Are psychotropics drugs used in pregnancy?

Pharmacoepidemiology and Drug Safety, 2007

Purpose To assess the prevalence and characteristics of psychiatric drug use in pregnancy. Method... more Purpose To assess the prevalence and characteristics of psychiatric drug use in pregnancy. Methods A prospective observational study was performed on a total of 1332 consecutive women admitted for delivery, during a 3 months period, in the public obstetric services of Tenerife Island (covering a population of 1 000 000 inhabitants). Results Less than 4% (3.6%) of the women recognised having a psychiatric disorder, and only 2.5% were receiving psychiatric drug treatment at the moment they knew they were pregnant; of those, 68.7% introduced substantial modifications in their treatment at that moment, 47.9% did not report any change with respect to the period before pregnancy and 35.4% recognised that their mood was worse than previously. Although patients affected by a psychiatric disorder registered a higher rate of abdominal delivery, no differences in delivery or obstetric complications were found between women with and without psychiatric illness or in relation to psychiatric drug treatment. Conclusions Compared to the literature, the studied population shows a lower rate of psychiatric problems and pharmacological treatment. This might reflect underrecognition or undertreatment.

Research paper thumbnail of Diagnóstico prenatal de una trisomia parcial 5p asociada a hiperecogeneicidad intestinal

… e investigación en …, 2012

Resumen Paciente de 30 años de edad, a la que a las 20 semanas de gestación se le realiza una amn... more Resumen Paciente de 30 años de edad, a la que a las 20 semanas de gestación se le realiza una amniocentesis por presentar feto con pies equinovaros, hiperecogeneicidad intestinal y quiste de los plexos coroideos. En el estudio citogenético se diagnosticó una ...

Research paper thumbnail of Prenatal diagnosis of werdnig‐hoffmann disease: DNA analysis of a mummified umbilical cord using closely linked microsatellite markers

Research paper thumbnail of P15.12: Early prenatal diagnosis of vein of Galen aneurysmal malformation

Ultrasound in Obstetrics and Gynecology, 2004

Research paper thumbnail of Cesarean Scar Hysterotomy: Assessment by Three-dimensional Transvaginal Ultrasound Scan

Donald School Journal of Ultrasound in Obstetrics and Gynecology

Objective The combined study of two-dimensional (2D) and three-dimensional (3D) sonographic recor... more Objective The combined study of two-dimensional (2D) and three-dimensional (3D) sonographic records may be useful to diagnose wound dehiscence from hysterotomy and forecast the well-being of future gestations. In that respect, irregular cicatrization patterns can be identified from the early puerperium over the whole postparturition recovery period, and may encourage the need for further cesarean in new pregnancies to come. Subjects and Methods A random sample of 42 female patients were subjected to transvaginal sonographic exploration at three sampling times, namely 4 days, 4 months, and 1 year following hysterotomy. All of these women recovered successfully from their cesarean and were discharged from hospital 5 days after parturition. The 2D and 3D surveys were subsequently undertaken at each of the three study times. Four days after surgery, the 2D ultrasound scan aimed at evaluating the early evolution of the uterine scar. On the contrary, 3D echographies were implemented fram...

Research paper thumbnail of WS15-02Fetal biophysical profile and kinetic measurement: Doppler contribution

Ultrasound in Obstetrics and Gynecology, 2002

ABSTRACT

Research paper thumbnail of Detección ecográfica y pronóstico de la ventriculomegalia fetal

Revista chilena de obstetricia y ginecología, 2012

Research paper thumbnail of Tumor de Brenner maligno: caso clínico

Revista chilena de obstetricia y ginecología, 2012

El tumor de Brenner es una neoplasia rara, que representa el 1-2 % de las neoplasias de ovario. L... more El tumor de Brenner es una neoplasia rara, que representa el 1-2 % de las neoplasias de ovario. La mayoría son benignas, pero existe un pequeño porcentaje de casos de tumor de Brenner maligno, entre ellos el caso que se presenta. Se trata de una mujer de 41 años que presentó una tumoración ovárica cuyo resultado anatomopatológico fue de carcinoma pobremente diferenciado, con asociación de tumor tipo Brenner maligno. A pesar de ser diagnosticado en estadio precoz, este caso destaca por su mal pronóstico. PALABRAS CLAVE: Tumor de Brenner, cáncer de ovario, células transicionales, núcleos en "grano de café" SUMMARY Brenner tumor is a rare neoplasia, accounting for 1-2% of ovarian cancer. Most of them are benign, but there are a small percentage of malignant Brenner tumors, including the case presented. This is a 41-yearold woman who presented an ovarian tumor. Definitive histological result showed a poorly differentiated carcinoma, with association of malignant Brenner tumor. Despite being diagnosed in early stages, this case stands out for its poor prognosis.

Research paper thumbnail of Diagnóstico ecográfico prenatal y resultados neonatales de la malformación adenomatoidea quística pulmonar

Revista chilena de pediatría, 2018

Introduction: Congenital cystic adenomatoid malformation (CCAM) is a rare congenital lung disease... more Introduction: Congenital cystic adenomatoid malformation (CCAM) is a rare congenital lung disease, and in the most of cases, prenatal diagnosis is feasible. There are discrepancies regarding prenatal management and postpartum treatment. Objective: To analyze prenatally diagnosed CCAM in our hospitals, in order to evaluate ultrasound findings with fetal and postnatal evolution. Patients and Method: Retrospective study of all cases diagnosed prenatally by ultrasound between 2005 and 2016 in two reference hospitals. The ultrasounds were performed using high-resolution ultrasound scanners, Toshiba Xario and Voluson 730 Expert Pro, with follow-up from diagnosis to delivery. The variables analyzed included gestational age at diagnosis, the characteristics of the lung lesion, associated malformations, cytogenetic study, the evolution of pregnancy, type of delivery, presence of respiratory distress, need for complementary imaging tests, pediatric clinical course, and necessary postnatal treatments. It was considered a resolution the total disappearance of the lesion in the prenatal ultrasound or that the postnatal chest X-ray showed no lesion. Results: 17 cases were prenatally diagnosed. The evolution ranges from the prenatal resolution of the lesion to the persistence after birth. Three patients voluntarily decided to have an abortion due to ultrasound findings of poor prognosis. Of the fourteen remaining cases there were no cases of fetal or neonatal deaths, one case required surgery after birth and four patients had mild symptoms during the first year of life. One case of false negative with neonatal death has been reported which necropsy reported as CCAM type 0. Conclusions: This pulmonary malformation presents good prognosis, excluding cases with fetal hydrops. Two-dimensional ultrasound is usually enough for diagnosis and follow-up. Computed tomography is the technique of choice to confirm the resolution of lesions after birth. Surgical treatment is preferable over conservative management, although it is unknown if the potential complications of this disease, even when asymptomatic, justify surgical morbidity.

Research paper thumbnail of Can 3-dimensional Ultrasound Change Gynecological Ultrasonographic Examination?

Donald School Journal of Ultrasound in Obstetrics and Gynecology, 2009

Objective To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ult... more Objective To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ultrasonography and whether it provides additional advantages in gynecologic diagnosis. Material and methods We performed a prospective study in 46 women who underwent 2D and 3D transvaginal scans successively. Three 3D volumes (uterus and each ovary) were acquired and evaluated 4 months later on a personal computer. We compared 2D and 3D scans in relation to sonographic diagnosis and biometry and the time spent. Results There was complete agreement between 2D and 3D techniques for sonographic diagnosis (31 normal exams, 16 adnexal cysts and seven myomas), except for the visualization and measurement of the uterine cervix. The mean time for 2D scans was 3.29 ± 1.32 minutes and was 2.96 ± 0.58 minutes for 3D examination (P = 0.076). The time required to acquire 3D volumes was only 1 hour, freeing 1 hour and 32 minutes for the performance of new scans. Conclusions Transvaginal 3D ultrasonogra...

Research paper thumbnail of The labor induction: integrated clinical and sonographic variables that predict the outcome

Journal of Perinatology, 2007

Objective: To analyze the clinical and sonographic variables that predicts the success of labor i... more Objective: To analyze the clinical and sonographic variables that predicts the success of labor induction. Study design: We studied the Bishop score, cervical length and parity in 196 pregnant women in the prediction of successful vaginal delivery within 24 h of induction. Logistic regression and segmentation analysis were performed. Results: Cervical length (odds ratio (OR) 1.089, P<0.001), Bishop score (OR 0.751, P ¼ 0.001) and parity (OR 4.7, P<0.001) predict the success of labor induction. In a global analysis of the variables studied, the best statistic sequence that predicts the labor induction was found when we introduced parity in the first place. The success of labor induction in nulliparous was 50.8 and 83.3% in multiparous women (P ¼ 0.0001). Conclusions: Cervical length, Bishop score and parity, integrated in a flow chart, provide independent prediction of vaginal delivery within 24 h of induction.

Research paper thumbnail of Hidrops Fetal Como Manifestación Ecográfica De Una Enfermedad Familiar: Incontinentia Pigmenti (Síndrome De Bloch-Sulzberger)

Revista chilena de obstetricia y ginecología, 2010

Research paper thumbnail of Sonography of pelvic infection

The Ultrasound Review of Obstetrics & Gynecology, 2005

We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute P... more We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute PID (acute salpingitis) begins with a challenge for the doctor, due to the little sensibility of the clinic's criteria. The accumulation of pus inside the fallopian tube gives a location for the tubaric abscess or pyosalpinx, whose characteristic signal is the presence of purulent material in considerable quantities and is visible by means of a sonograph inside the tubal light. We refer a series of characteristic sings that advise us.

Research paper thumbnail of Sonography of pelvic infection

The Ultrasound Review of Obstetrics & Gynecology, 2005

We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute P... more We describe sonographic findings of pelvis inflammatory disease. The diagnosis of initial acute PID (acute salpingitis) begins with a challenge for the doctor, due to the little sensibility of the clinic's criteria. The accumulation of pus inside the fallopian tube gives a location for the tubaric abscess or pyosalpinx, whose characteristic signal is the presence of purulent material in considerable quantities and is visible by means of a sonograph inside the tubal light. We refer a series of characteristic sings that advise us.

Research paper thumbnail of Determinants of organochlorine levels detectable in the amniotic fluid of women from Tenerife Island (Canary Islands, Spain)

Environmental Research, 2009

Organochlorines (OCs) tend to accumulate in human tissues and can be measured in amniotic fluid (... more Organochlorines (OCs) tend to accumulate in human tissues and can be measured in amniotic fluid (AF). The detection of OCs in AF samples reflects intrauterine exposure of human beings to these persistent organic pollutants. The present study was performed to evaluate the level of contamination of AF by OCs in 100 pregnant women from Tenerife Island (Canary Islands, Spain). Gas chromatography/mass spectrometry (GC/MS) was used to identify and quantify the analytes, including 7 polychlorobiphenyl (PCB) congeners and 18 OC pesticides and metabolites. The majority of the AF samples (67%) showed some detectable OC-residue, hexachlorobenzene (HCB) being the most frequently detected compound (66% of the samples) and at the highest concentration (median 0.023 ng/ml). Lindane was also detected in 28% of the samples. Inverse associations were found between previous lactation and hexachlorocyclohexane isomers (HCH) and cyclodienes in the group of younger women (p ¼ 0.037 and p ¼ 0.027, respectively). Unexpectedly, serum values of HCB (r ¼ À0.414; p ¼ 0.04), g-HCH (r ¼ À0.294; p ¼ 0.035), and P OCs (r ¼ À0.350; p ¼ 0.014) were negatively related to age. Even more, women with detectable levels of HCH isomers were younger (33.974.9 years) than women with undetectable levels of them (36.174.9 years; p ¼ 0.035). We conclude that approximately one in two fetuses in the Canary Islands is exposed to OCs in utero, and that, therefore, the exposure of young women from these Islands to some HCH isomers persists nowadays. Because prenatal exposure to these chemicals may be a causative factor in adverse health trends, further studies are required to enhance preventive measures.

Research paper thumbnail of Luis T Mercé et al 6 Can 3-dimensional Ultrasound Change

Objective: To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ul... more Objective: To verify whether 3D transvaginal ultrasonography is as accurate as 2D conventional ultrasonography and whether it provides additional advantages in gynecologic diagnosis. Material and methods: We performed a prospective study in 46 women who underwent 2D and 3D transvaginal scans successively. Three 3D volumes (uterus and each ovary) were acquired and evaluated 4 months later on a personal computer. We compared 2D and 3D scans in relation to sonographic diagnosis and biometry and the time spent. Results: There was complete agreement between 2D and 3D techniques for sonographic diagnosis (31 normal exams, 16 adnexal cysts and seven myomas), except for the visualization and measurement of the uterine cervix. The mean time for 2D scans was 3.29 ± 1.32 minutes and was 2.96 ± 0.58 minutes for 3D examination (P = 0.076). The time required to acquire 3D volumes was only 1 hour, freeing 1 hour and 32 minutes for the performance of new scans. Conclusions: Transvaginal 3D ultrason...

Research paper thumbnail of 50 th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida Cambridge , UK 30 August – 2 September 2006

The 50 Annual Scientific Meeting of the Society for Research into Hydrocephalus and Spina Bifida ... more The 50 Annual Scientific Meeting of the Society for Research into Hydrocephalus and Spina Bifida took place in the historic surroundings of Queens’ College in Cambridge, England. Delegates were warmly welcomed by Professor John Pickard and his organising team from the Department of Academic Neurosurgery, and we are especially indebted to Dr. Hugh Richards for his tireless work to make this conference a success. A feature of the 50 anniversary meeting was a presentation from archivists Ewen Mackinnon and Leonie Holgate, featuring documents and photographs illustrating the society’s activities over the past 50 years. We were also happy to welcome a large delegation from Association for Spina Bifida and Hydrocephalus, who helped with the administration of the conference as well as making a contribution to proceedings. Their chief executive, Andrew Russell, gave a talk outlining his tireless efforts in the cause of flour fortification with folic acid. Cambridge is an ancient and beautif...

Research paper thumbnail of �Puede la ecograf�a tridimensional cambiar la exploraci�n ecogr�fica ginecol�gica en nuestro medio?

Research paper thumbnail of Ultrasound-guided fetal invasive procedures

Textbook of Perinatal Medicine, Second Edition, 2006

Research paper thumbnail of Ultrasonographic signs of poor pregnancy outcome

The Ultrasound Review of Obstetrics & Gynecology, 2005

The frequency of spontaneous abortion, when it is considered from its very beginning, along with ... more The frequency of spontaneous abortion, when it is considered from its very beginning, along with the theoretical knowledge of the causes of the abortion, should provide a perspective to the obstetrician that, performing a sonographic exploration finds discoveries that cannot correspond to those characterizing a normal pregnancy. The precocity of the realization of sonographic explorations in the pregnancy will allow diagnosis of many more cases of spontaneous interruptions of the development of pregnancy. New sonographic imaging techniques including threedimensional (3D) sonography can provide additional information regarding the presence of structural anomalies via 3D volume acquisition, like craniofacial deformities, clefts, neural tube defects, abdominal wall defects, and caudal regression syndrome. It may give further details regarding the timing of embryonic/ fetal demise in early pregnancy. Sufficient informational value is regularly obtained in cases having a crown-rump length >8 mm.

Research paper thumbnail of Are psychotropics drugs used in pregnancy?

Pharmacoepidemiology and Drug Safety, 2007

Purpose To assess the prevalence and characteristics of psychiatric drug use in pregnancy. Method... more Purpose To assess the prevalence and characteristics of psychiatric drug use in pregnancy. Methods A prospective observational study was performed on a total of 1332 consecutive women admitted for delivery, during a 3 months period, in the public obstetric services of Tenerife Island (covering a population of 1 000 000 inhabitants). Results Less than 4% (3.6%) of the women recognised having a psychiatric disorder, and only 2.5% were receiving psychiatric drug treatment at the moment they knew they were pregnant; of those, 68.7% introduced substantial modifications in their treatment at that moment, 47.9% did not report any change with respect to the period before pregnancy and 35.4% recognised that their mood was worse than previously. Although patients affected by a psychiatric disorder registered a higher rate of abdominal delivery, no differences in delivery or obstetric complications were found between women with and without psychiatric illness or in relation to psychiatric drug treatment. Conclusions Compared to the literature, the studied population shows a lower rate of psychiatric problems and pharmacological treatment. This might reflect underrecognition or undertreatment.

Research paper thumbnail of Diagnóstico prenatal de una trisomia parcial 5p asociada a hiperecogeneicidad intestinal

… e investigación en …, 2012

Resumen Paciente de 30 años de edad, a la que a las 20 semanas de gestación se le realiza una amn... more Resumen Paciente de 30 años de edad, a la que a las 20 semanas de gestación se le realiza una amniocentesis por presentar feto con pies equinovaros, hiperecogeneicidad intestinal y quiste de los plexos coroideos. En el estudio citogenético se diagnosticó una ...

Research paper thumbnail of Prenatal diagnosis of werdnig‐hoffmann disease: DNA analysis of a mummified umbilical cord using closely linked microsatellite markers

Research paper thumbnail of P15.12: Early prenatal diagnosis of vein of Galen aneurysmal malformation

Ultrasound in Obstetrics and Gynecology, 2004

Research paper thumbnail of Cesarean Scar Hysterotomy: Assessment by Three-dimensional Transvaginal Ultrasound Scan

Donald School Journal of Ultrasound in Obstetrics and Gynecology

Objective The combined study of two-dimensional (2D) and three-dimensional (3D) sonographic recor... more Objective The combined study of two-dimensional (2D) and three-dimensional (3D) sonographic records may be useful to diagnose wound dehiscence from hysterotomy and forecast the well-being of future gestations. In that respect, irregular cicatrization patterns can be identified from the early puerperium over the whole postparturition recovery period, and may encourage the need for further cesarean in new pregnancies to come. Subjects and Methods A random sample of 42 female patients were subjected to transvaginal sonographic exploration at three sampling times, namely 4 days, 4 months, and 1 year following hysterotomy. All of these women recovered successfully from their cesarean and were discharged from hospital 5 days after parturition. The 2D and 3D surveys were subsequently undertaken at each of the three study times. Four days after surgery, the 2D ultrasound scan aimed at evaluating the early evolution of the uterine scar. On the contrary, 3D echographies were implemented fram...

Research paper thumbnail of WS15-02Fetal biophysical profile and kinetic measurement: Doppler contribution

Ultrasound in Obstetrics and Gynecology, 2002

ABSTRACT

Research paper thumbnail of Detección ecográfica y pronóstico de la ventriculomegalia fetal

Revista chilena de obstetricia y ginecología, 2012