Juana Ortellado - Academia.edu (original) (raw)

Papers by Juana Ortellado

Research paper thumbnail of Serogrupos y resistencia antimicrobiana de Neisseria meningitidis causantes de enfermedad invasiva en Paraguay

Memorias del Instituto de Investigaciones en Ciencias de la Salud

La enfermedad meningocócica representa un problema de salud pública y una de las principales caus... more La enfermedad meningocócica representa un problema de salud pública y una de las principales causas de morbilidad y mortalidad en todo el mundo. Los serogrupos que causan la mayor carga de enfermedad a nivel global son A, B, C, W e Y. El objetivo del estudio fue describir los serogrupos y la resistencia antimicrobiana de Neisseria meningitidis aisladas de enfermedad invasiva en Paraguay durante el periodo 2010-2020. Se estudiaron todas las muestras de líquido cefalorraquídeo y sangre con aislamientos o detección de ADN por PCR de N. meningitidis de pacientes de diversas edades, que fueron remitidas al Laboratorio Central de Salud Pública durante el periodo 2010-2020, dentro del marco de la vigilancia epidemiológica de meningitis (n=163) en Paraguay. La mayor frecuencia de hallazgos de N. meningitidis se observó en el grupo de edad de < 1 año. El 25,7% de los casos correspondió al serogrupo B, el 52,1% al serogrupo C, 18,4% al serogrupo W y 3,7% al serogrupo Y. En el 2018, se evid...

Research paper thumbnail of Content Alerts

This article cites 16 articles, 12 of which can be accessed free

Research paper thumbnail of See Profile

All in-text references underlined in blue are linked to publications on ResearchGate, letting you... more All in-text references underlined in blue are linked to publications on ResearchGate, letting you access and read them immediately.

Research paper thumbnail of Prevalencia de serotipos y resistencia a antibióticos betalactámicos de Streptococcus pneumoniae en menores de 6 años. Paraguay 2000 a 2008 Streptococcus pneumoniae isolated in Paraguay in children under six years old from 2000 to 2008: serotypes and antibiotic resistance

We determined the frequency and distribution of S. pneumoniae serotypes in children under six yea... more We determined the frequency and distribution of S. pneumoniae serotypes in children under six years old in Paraguay from 2000 to 2008 and the sensibility profile to penicillin.

Research paper thumbnail of Resistencia plasmídica a colistin por el gen mcr-1 en Enterobacteriaceae en Paraguay

La resistencia a las polimixinas mediada por plasmidos (gen mcr-1) representa una amenaza para la... more La resistencia a las polimixinas mediada por plasmidos (gen mcr-1) representa una amenaza para la salud publica, puesto que colistina es utilizada en la practica medica como una de las ultimas alternativas para el tratamiento de germenes multiresistentes. Este estudio describe la circulacionde cepas de Enterobacterias que portan este gen de resistencia, aisladas de pacientes hospitalizados, asi como tambien de la comunidad.

Research paper thumbnail of Plasmid-Mediated Colistin Resistance Gene mcr-1 in an Escherichia coli ST10 Bloodstream Isolate in the Sultanate of Oman

Microbial Drug Resistance, 2017

Aims: To identify plasmid-mediated colistin resistance in clinical Enterobacteriaceae isolates in... more Aims: To identify plasmid-mediated colistin resistance in clinical Enterobacteriaceae isolates in Oman, where this resistance mechanism has not been encountered yet. Materials/Methods: Twenty-two colistin-resistant Enterobacteriaceae clinical isolates collected between July 2014 and June 2016 in a tertiary care hospital in Muscat were screened by PCR for the mcr-1 and mcr-2 genes. The strain identified as mcr-1 positive was genotyped and its antibiotic susceptibility was established. The mcr-1 containing plasmid was mobilized into Escherichia coli K-12 and its sequence was determined. Results: A single E. coli isolate (OM97) carrying mcr-1 gene was identified, while no strains carrying the mcr-2 gene was found. E. coli OM97 was isolated in June 2016 from blood culture of a male patient with multiple comorbidities. It belonged to ST10. Beyond colistin, it was resistant to amoxicillin–clavulanic acid, piperacillin–tazobactam, amikacin, ciprofloxacin, tetracycline, and cotrimoxazole. The mcr-1 gene was locat...

Research paper thumbnail of Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolates Collected in Asunción, Paraguay

Journal of Clinical Microbiology, Jul 1, 2007

We characterized 34 methicillin-resistant Staphylococcus aureus strains isolated in Paraguay in 2... more We characterized 34 methicillin-resistant Staphylococcus aureus strains isolated in Paraguay in 2005. The strains belonged to two clones. The major clone (sequence type 5 [ST5] or ST221, spa type t149, staphylococcal cassette chromosome mec [SCCmec] type I) was similar to the Cordobes/Chilean clone spreading through South America, and the minor clone (ST239 or ST889, spa type t037, SCCmec type IIIA) was related to the Brazilian clone.

Research paper thumbnail of Resistencia a antibióticos no betalactámicos de aislamientos invasores de Streptococcus pneumoniae en niños latinoamericanos: SIREVA II, 2000-2005

Revista Panamericana de Salud Pública, 2009

Resistencia a antibióticos no betalactámicos de aislamientos invasores de Streptococcus pneumonia... more Resistencia a antibióticos no betalactámicos de aislamientos invasores de Streptococcus pneumoniae en niños latinoamericanos.

Research paper thumbnail of Nasal behave of staphylococcus aureus in personal of the hospital in intensive cares adults units

Objectives: A multicenter study was performed with the aim of determining the frequency of nasal ... more Objectives: A multicenter study was performed with the aim of determining the frequency of nasal carriers of S. aureus, antimicrobial susceptibility and risk factors of the carrying in Health staff of Intensive Care Units of Adults (UCIA). Design: Prospective observational study of transverse cut, made in November of 2002 in Health staff of UCIA from four public Hospitals (Clinical Hospital, National Hospital, Social Preventive Institute and Medical Emergency Center). Variable: age, sex, hospitality labor, and admission, preview surgery, preview use of antibiotics and topics corticoids, nasal carrying of S. aureus and antimicrobial susceptibility. It was made nasal swabs to detect carriage of S. aureus in 142 individuals. The isolations were confirmed as S. aureus based on catalase, coagulas and agglutination test. The susceptibility testing was performed by the Disk diffusion method for methicillin (with 1 g oxacilin disc), vancomycin (VAN) in agar MuellerHinton. Results were inter...

Research paper thumbnail of Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay

Journal of Antimicrobial Chemotherapy

function. Sequence analysis was conducted using the ORF Finder and the BLASTp functions at NCBI. ... more function. Sequence analysis was conducted using the ORF Finder and the BLASTp functions at NCBI. For each isolate, multiresistance gene cluster-carrying contigs ranging in size between 9613 bp and 9690 bp were obtained. They comprised the region from the aadE gene to downstream of lnu(B). A comparison with the 17577 bp sequence of the cluster located on the multiresistance plasmid pV7037 (GenBank accession number JX560992) revealed a single nucleotide exchange (A C) in the MRSA CC398 isolate at position 9474 in the non-coding region between spw and orf4. An additional nucleotide exchange (A G), which, however, did not change the amino acid sequence, was seen in all 12 isolates at position 10071 within orf4. All CC9 isolates carried a transposase gene downstream of the gene lnu(B). The CC398 isolate exhibited at this position two genes coding for a resolvase and a nucleotidyltransferase with greatest amino acid identities of 99.5% and 100%, respectively, with the corresponding proteins from Enterococcus faecium Aus0085 plasmid p3 (GenBank accession number NC_021988.1). In all cases, the repeatedly negative results of conjugation, protoplast transformation and electrotransformation experiments suggested that the cluster was located in the chromosomal DNA, as previously seen for the majority of the Chinese porcine MRSA CC9 isolates and the Spanish MRSA ST398 and MSSA ST9 isolates of human origin. 1,2 In conclusion, a large part of the pV7037-associated multiresistance gene cluster, including the novel resistance genes lsa(E) and spw, was identified in MRSA CC9 isolated from different food samples and a butcher in Hong Kong as well as from a single MRSA CC398 of human origin in Germany. These and previous observations suggest that a multiresistance gene cluster, closely related to the one that has recently been detected in enterococci of human and porcine origin, 4 has been acquired by MRSA/MSSA CC9 and CC398 several times on different occasions in Europe and Asia.

Research paper thumbnail of Plasmid-Mediated Colistin Resistance Gene mcr-1 in Enterobacteriaceae in Paraguay

Resistencia plasmídica a colistin por el gen mcr-1 en Enterobacteriaceae en Paraguay RESUMEN La r... more Resistencia plasmídica a colistin por el gen mcr-1 en Enterobacteriaceae en Paraguay RESUMEN La resistencia a las polimixinas mediada por plásmidos (gen mcr-1) representa una amenaza para la salud pública, puesto que colistina es utilizada en la práctica médica como una de las últimas alternativas para el tratamiento de gérmenes multiresistentes. Este estudio describe la circulaciónde cepas de Enterobacterias que portan este gen de resistencia, aisladas de pacientes hospitalizados, así como también de la comunidad. Los hallazgos de la Red de Vigilancia de la Resistencia a los Antimicrobianos-Paraguay fueron de casi el 5 % (4,7) en cepas remitidas con criterio de sospecha, siendo las especies involucradas Escherichiacoli, K l e b s i e l l a p n e u m o n i a e y S a l m o n e l l a Schwarzengrund. Además, por métodos moleculares se confirmaron en todas ellas la portación de otros genes de resistencia (KPC, CTX-M, Qnr B, Qnr S, aac (6`)-Ib-cr) asociados al mcr-1.

Research paper thumbnail of Frecuencia de Streptococcus pneumoniae aislados de enfermedad invasiva en Paraguay, serotipos y perfil de sensibilidad (2010-2018)

Memorias del Instituto de Investigaciones en Ciencias de la Salud

Research paper thumbnail of Staphylococcus aureus adquiridos en la comunidad: caracterización clínica, fenotípica y genotípica de aislados en niños paraguayos

Revista chilena de infectología, Dec 1, 2016

Los autores declaran no tener conflictos de interés. El trabajo fue financiado con el premio LabC... more Los autores declaran no tener conflictos de interés. El trabajo fue financiado con el premio LabCiencia otorgado en el VI Congreso Paraguayo de Química, llevado a cabo en junio de 2008 en Asunción, Paraguay. El componente de análisis molecular ha sido realizado con reactivos del Departamento de Biología Molecular y Biotecnología del IICS-UNA y con financiación obtenida del premio LAB Ciencia del VI Congreso Paraguayo de Química 2008.

Research paper thumbnail of Genomic diversity of the human pathogen Paracoccidioides across the South American continent

Fungal Genetics and Biology

Research paper thumbnail of Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) clones from Paraguayan children

The Journal of Infection in Developing Countries

Introduction: Staphylococcus aureus is considered one of the most important human pathogens, and ... more Introduction: Staphylococcus aureus is considered one of the most important human pathogens, and its levels of resistance to methicillin have increased even in strains isolated from people without nosocomial risk factors. Molecular analysis is essential for understanding the patterns of dissemination. The objective of this study was to identify community-acquired methicillin-resistant S. aureus (CA-MRSA) clones that infected Paraguayan children patients in two periods of time. Methodology: An observational, descriptive study was designed to determine the genetic variability of 115 isolates of CA-MRSA recovered from children who attended four reference centers in Paraguay between 2009-2010 and 2012-2013. Results: The combined use of Pulsed Field Gel Electrophoresis (PFGE), Multi-Locus Sequencing Typing, Multi-Locus Variable Analysis (MLVA) and Spa typing techniques allowed the identification of two dominant clones: ST30-IV-t019 (77%) and ST5-IV-t311 (10%), and the establishment of th...

Research paper thumbnail of Estudio epidemiológico de Haemophilus influenzae causante de enfermedad invasiva y no invasiva en Paraguay (1999-2017)

Enfermedades Infecciosas y Microbiología Clínica

Research paper thumbnail of Encuesta N 18 del Comité de Resistencia a Antimicrobianos de la Asociación Panamericana de Infectología (API)

Comentarios: • En algunos de los países que indican "no sabe-mos", han detectado la pre... more Comentarios: • En algunos de los países que indican "no sabe-mos", han detectado la presencia de carbapenemasas, pero no han podido determinar el tipo. • Dos (2) de tres (3) países que indican la pre-sencia de otras carbapenemasas, las han encontrado conjuntamente con Kpc.

Research paper thumbnail of Portación Nasal de Staphylococcus aureus en Personal Hospitalario en Unidades de Cuidados Intensivos Adultos

Anales De La Facultad De Ciencias Medicas, Jun 1, 2008

Research paper thumbnail of Detección molecular de belactamasas de espectro extendido (BLEE) en enterobacterias aisladas en Asunción

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2016

Research paper thumbnail of Nasal behave of staphylococcus aureus in personal of the hospital in intensive cares adults units

Anales De La Facultad De Ciencias Medicas, Jun 1, 2008

Research paper thumbnail of Serogrupos y resistencia antimicrobiana de Neisseria meningitidis causantes de enfermedad invasiva en Paraguay

Memorias del Instituto de Investigaciones en Ciencias de la Salud

La enfermedad meningocócica representa un problema de salud pública y una de las principales caus... more La enfermedad meningocócica representa un problema de salud pública y una de las principales causas de morbilidad y mortalidad en todo el mundo. Los serogrupos que causan la mayor carga de enfermedad a nivel global son A, B, C, W e Y. El objetivo del estudio fue describir los serogrupos y la resistencia antimicrobiana de Neisseria meningitidis aisladas de enfermedad invasiva en Paraguay durante el periodo 2010-2020. Se estudiaron todas las muestras de líquido cefalorraquídeo y sangre con aislamientos o detección de ADN por PCR de N. meningitidis de pacientes de diversas edades, que fueron remitidas al Laboratorio Central de Salud Pública durante el periodo 2010-2020, dentro del marco de la vigilancia epidemiológica de meningitis (n=163) en Paraguay. La mayor frecuencia de hallazgos de N. meningitidis se observó en el grupo de edad de < 1 año. El 25,7% de los casos correspondió al serogrupo B, el 52,1% al serogrupo C, 18,4% al serogrupo W y 3,7% al serogrupo Y. En el 2018, se evid...

Research paper thumbnail of Content Alerts

This article cites 16 articles, 12 of which can be accessed free

Research paper thumbnail of See Profile

All in-text references underlined in blue are linked to publications on ResearchGate, letting you... more All in-text references underlined in blue are linked to publications on ResearchGate, letting you access and read them immediately.

Research paper thumbnail of Prevalencia de serotipos y resistencia a antibióticos betalactámicos de Streptococcus pneumoniae en menores de 6 años. Paraguay 2000 a 2008 Streptococcus pneumoniae isolated in Paraguay in children under six years old from 2000 to 2008: serotypes and antibiotic resistance

We determined the frequency and distribution of S. pneumoniae serotypes in children under six yea... more We determined the frequency and distribution of S. pneumoniae serotypes in children under six years old in Paraguay from 2000 to 2008 and the sensibility profile to penicillin.

Research paper thumbnail of Resistencia plasmídica a colistin por el gen mcr-1 en Enterobacteriaceae en Paraguay

La resistencia a las polimixinas mediada por plasmidos (gen mcr-1) representa una amenaza para la... more La resistencia a las polimixinas mediada por plasmidos (gen mcr-1) representa una amenaza para la salud publica, puesto que colistina es utilizada en la practica medica como una de las ultimas alternativas para el tratamiento de germenes multiresistentes. Este estudio describe la circulacionde cepas de Enterobacterias que portan este gen de resistencia, aisladas de pacientes hospitalizados, asi como tambien de la comunidad.

Research paper thumbnail of Plasmid-Mediated Colistin Resistance Gene mcr-1 in an Escherichia coli ST10 Bloodstream Isolate in the Sultanate of Oman

Microbial Drug Resistance, 2017

Aims: To identify plasmid-mediated colistin resistance in clinical Enterobacteriaceae isolates in... more Aims: To identify plasmid-mediated colistin resistance in clinical Enterobacteriaceae isolates in Oman, where this resistance mechanism has not been encountered yet. Materials/Methods: Twenty-two colistin-resistant Enterobacteriaceae clinical isolates collected between July 2014 and June 2016 in a tertiary care hospital in Muscat were screened by PCR for the mcr-1 and mcr-2 genes. The strain identified as mcr-1 positive was genotyped and its antibiotic susceptibility was established. The mcr-1 containing plasmid was mobilized into Escherichia coli K-12 and its sequence was determined. Results: A single E. coli isolate (OM97) carrying mcr-1 gene was identified, while no strains carrying the mcr-2 gene was found. E. coli OM97 was isolated in June 2016 from blood culture of a male patient with multiple comorbidities. It belonged to ST10. Beyond colistin, it was resistant to amoxicillin–clavulanic acid, piperacillin–tazobactam, amikacin, ciprofloxacin, tetracycline, and cotrimoxazole. The mcr-1 gene was locat...

Research paper thumbnail of Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolates Collected in Asunción, Paraguay

Journal of Clinical Microbiology, Jul 1, 2007

We characterized 34 methicillin-resistant Staphylococcus aureus strains isolated in Paraguay in 2... more We characterized 34 methicillin-resistant Staphylococcus aureus strains isolated in Paraguay in 2005. The strains belonged to two clones. The major clone (sequence type 5 [ST5] or ST221, spa type t149, staphylococcal cassette chromosome mec [SCCmec] type I) was similar to the Cordobes/Chilean clone spreading through South America, and the minor clone (ST239 or ST889, spa type t037, SCCmec type IIIA) was related to the Brazilian clone.

Research paper thumbnail of Resistencia a antibióticos no betalactámicos de aislamientos invasores de Streptococcus pneumoniae en niños latinoamericanos: SIREVA II, 2000-2005

Revista Panamericana de Salud Pública, 2009

Resistencia a antibióticos no betalactámicos de aislamientos invasores de Streptococcus pneumonia... more Resistencia a antibióticos no betalactámicos de aislamientos invasores de Streptococcus pneumoniae en niños latinoamericanos.

Research paper thumbnail of Nasal behave of staphylococcus aureus in personal of the hospital in intensive cares adults units

Objectives: A multicenter study was performed with the aim of determining the frequency of nasal ... more Objectives: A multicenter study was performed with the aim of determining the frequency of nasal carriers of S. aureus, antimicrobial susceptibility and risk factors of the carrying in Health staff of Intensive Care Units of Adults (UCIA). Design: Prospective observational study of transverse cut, made in November of 2002 in Health staff of UCIA from four public Hospitals (Clinical Hospital, National Hospital, Social Preventive Institute and Medical Emergency Center). Variable: age, sex, hospitality labor, and admission, preview surgery, preview use of antibiotics and topics corticoids, nasal carrying of S. aureus and antimicrobial susceptibility. It was made nasal swabs to detect carriage of S. aureus in 142 individuals. The isolations were confirmed as S. aureus based on catalase, coagulas and agglutination test. The susceptibility testing was performed by the Disk diffusion method for methicillin (with 1 g oxacilin disc), vancomycin (VAN) in agar MuellerHinton. Results were inter...

Research paper thumbnail of Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay

Journal of Antimicrobial Chemotherapy

function. Sequence analysis was conducted using the ORF Finder and the BLASTp functions at NCBI. ... more function. Sequence analysis was conducted using the ORF Finder and the BLASTp functions at NCBI. For each isolate, multiresistance gene cluster-carrying contigs ranging in size between 9613 bp and 9690 bp were obtained. They comprised the region from the aadE gene to downstream of lnu(B). A comparison with the 17577 bp sequence of the cluster located on the multiresistance plasmid pV7037 (GenBank accession number JX560992) revealed a single nucleotide exchange (A C) in the MRSA CC398 isolate at position 9474 in the non-coding region between spw and orf4. An additional nucleotide exchange (A G), which, however, did not change the amino acid sequence, was seen in all 12 isolates at position 10071 within orf4. All CC9 isolates carried a transposase gene downstream of the gene lnu(B). The CC398 isolate exhibited at this position two genes coding for a resolvase and a nucleotidyltransferase with greatest amino acid identities of 99.5% and 100%, respectively, with the corresponding proteins from Enterococcus faecium Aus0085 plasmid p3 (GenBank accession number NC_021988.1). In all cases, the repeatedly negative results of conjugation, protoplast transformation and electrotransformation experiments suggested that the cluster was located in the chromosomal DNA, as previously seen for the majority of the Chinese porcine MRSA CC9 isolates and the Spanish MRSA ST398 and MSSA ST9 isolates of human origin. 1,2 In conclusion, a large part of the pV7037-associated multiresistance gene cluster, including the novel resistance genes lsa(E) and spw, was identified in MRSA CC9 isolated from different food samples and a butcher in Hong Kong as well as from a single MRSA CC398 of human origin in Germany. These and previous observations suggest that a multiresistance gene cluster, closely related to the one that has recently been detected in enterococci of human and porcine origin, 4 has been acquired by MRSA/MSSA CC9 and CC398 several times on different occasions in Europe and Asia.

Research paper thumbnail of Plasmid-Mediated Colistin Resistance Gene mcr-1 in Enterobacteriaceae in Paraguay

Resistencia plasmídica a colistin por el gen mcr-1 en Enterobacteriaceae en Paraguay RESUMEN La r... more Resistencia plasmídica a colistin por el gen mcr-1 en Enterobacteriaceae en Paraguay RESUMEN La resistencia a las polimixinas mediada por plásmidos (gen mcr-1) representa una amenaza para la salud pública, puesto que colistina es utilizada en la práctica médica como una de las últimas alternativas para el tratamiento de gérmenes multiresistentes. Este estudio describe la circulaciónde cepas de Enterobacterias que portan este gen de resistencia, aisladas de pacientes hospitalizados, así como también de la comunidad. Los hallazgos de la Red de Vigilancia de la Resistencia a los Antimicrobianos-Paraguay fueron de casi el 5 % (4,7) en cepas remitidas con criterio de sospecha, siendo las especies involucradas Escherichiacoli, K l e b s i e l l a p n e u m o n i a e y S a l m o n e l l a Schwarzengrund. Además, por métodos moleculares se confirmaron en todas ellas la portación de otros genes de resistencia (KPC, CTX-M, Qnr B, Qnr S, aac (6`)-Ib-cr) asociados al mcr-1.

Research paper thumbnail of Frecuencia de Streptococcus pneumoniae aislados de enfermedad invasiva en Paraguay, serotipos y perfil de sensibilidad (2010-2018)

Memorias del Instituto de Investigaciones en Ciencias de la Salud

Research paper thumbnail of Staphylococcus aureus adquiridos en la comunidad: caracterización clínica, fenotípica y genotípica de aislados en niños paraguayos

Revista chilena de infectología, Dec 1, 2016

Los autores declaran no tener conflictos de interés. El trabajo fue financiado con el premio LabC... more Los autores declaran no tener conflictos de interés. El trabajo fue financiado con el premio LabCiencia otorgado en el VI Congreso Paraguayo de Química, llevado a cabo en junio de 2008 en Asunción, Paraguay. El componente de análisis molecular ha sido realizado con reactivos del Departamento de Biología Molecular y Biotecnología del IICS-UNA y con financiación obtenida del premio LAB Ciencia del VI Congreso Paraguayo de Química 2008.

Research paper thumbnail of Genomic diversity of the human pathogen Paracoccidioides across the South American continent

Fungal Genetics and Biology

Research paper thumbnail of Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) clones from Paraguayan children

The Journal of Infection in Developing Countries

Introduction: Staphylococcus aureus is considered one of the most important human pathogens, and ... more Introduction: Staphylococcus aureus is considered one of the most important human pathogens, and its levels of resistance to methicillin have increased even in strains isolated from people without nosocomial risk factors. Molecular analysis is essential for understanding the patterns of dissemination. The objective of this study was to identify community-acquired methicillin-resistant S. aureus (CA-MRSA) clones that infected Paraguayan children patients in two periods of time. Methodology: An observational, descriptive study was designed to determine the genetic variability of 115 isolates of CA-MRSA recovered from children who attended four reference centers in Paraguay between 2009-2010 and 2012-2013. Results: The combined use of Pulsed Field Gel Electrophoresis (PFGE), Multi-Locus Sequencing Typing, Multi-Locus Variable Analysis (MLVA) and Spa typing techniques allowed the identification of two dominant clones: ST30-IV-t019 (77%) and ST5-IV-t311 (10%), and the establishment of th...

Research paper thumbnail of Estudio epidemiológico de Haemophilus influenzae causante de enfermedad invasiva y no invasiva en Paraguay (1999-2017)

Enfermedades Infecciosas y Microbiología Clínica

Research paper thumbnail of Encuesta N 18 del Comité de Resistencia a Antimicrobianos de la Asociación Panamericana de Infectología (API)

Comentarios: • En algunos de los países que indican "no sabe-mos", han detectado la pre... more Comentarios: • En algunos de los países que indican "no sabe-mos", han detectado la presencia de carbapenemasas, pero no han podido determinar el tipo. • Dos (2) de tres (3) países que indican la pre-sencia de otras carbapenemasas, las han encontrado conjuntamente con Kpc.

Research paper thumbnail of Portación Nasal de Staphylococcus aureus en Personal Hospitalario en Unidades de Cuidados Intensivos Adultos

Anales De La Facultad De Ciencias Medicas, Jun 1, 2008

Research paper thumbnail of Detección molecular de belactamasas de espectro extendido (BLEE) en enterobacterias aisladas en Asunción

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2016

Research paper thumbnail of Nasal behave of staphylococcus aureus in personal of the hospital in intensive cares adults units

Anales De La Facultad De Ciencias Medicas, Jun 1, 2008