Judith Ramaley - Independent Researcher (original) (raw)
Papers by Judith Ramaley
New truths and old verities
New Directions for Higher Education, 2002
An environment for learning should be established that reflects an informed awareness of how peop... more An environment for learning should be established that reflects an informed awareness of how people learn, one that prepares all students for life and work in a society dominated by science and technology and is based on the expectation that all students can learn science and mathematics.
Journal of Higher Education Outreach and Engagement, Sep 26, 2014
The role of higher education is changing in today's world because the world itself is changing, a... more The role of higher education is changing in today's world because the world itself is changing, and complex problems confront us daily. This essay will explore the role of an emerging group of individuals who can serve as a bridge between the academic community and the world at large. These administrators, faculty members, staff, students, and community members can help create new opportunities for different disciplines to work together and for all parts of a campus community and members of the broader society to form new working relationships to address the complex problems of today's world. What role will these boundary spanners play in building a culture of engagement? How will their work change our ideas about faculty work, staff work, and the role of students in achieving the goals of the institution and in responding to the changing world around us?
Metropolitan universities, 2009
Higher education in this country has always been expected to serve the public good. Sometimes, th... more Higher education in this country has always been expected to serve the public good. Sometimes, the emphasis is on preparing educated citizens or practitioners in especially critical fields and how public service can deepen and enrich learning and prepare students to lead purposeful, responsible, and creative lives. Sometimes the focus is upon institutions themselves as major intellectual and cultural resources for a community. In this paper, based on the keynote presentation at the Community Engaged Scholarship for Health Collaborative's invitational symposium, the author explores four levels ofengagement: the individual, the academic community and its concepts ofscholarship, the institution and its relationships with its immediate community, and the role ofhigher education within a large network of interactions that define a region of innovation.
Fertility and Sterility, 1973
Although the effects of cold stress l and long-term 2, 3 or intermittent 4 , 5 heat stress upon f... more Although the effects of cold stress l and long-term 2, 3 or intermittent 4 , 5 heat stress upon fertility have been reported, little is known about the effect of a short-term, continuous heat exposure upon sexual maturation and subsequent fertility in prepubertal mice. In the study reported here, female C57/B16 mice were exposed to heat for 1 week during various stages of gestation and lactation, and their offspring were followed for several weeks thereafter in order to determine growth rates, survival rates, age at vaginal opening, vaginal cyclicity, percentage fertility, and length of conception time after exposure to males. MATERIALS AND METHODS Animals. Male and female C57/B16 mice of breeding age were obtained from Murphy Farms, Plainfield, Indiana. The mice were kept in disposable transparent plastic cages (dimensions: 7~ inches x 11~ inches) lined with Absorb-DriR litter, three females with litters plus one male per box or five females without litters plus one male per box. Ambient temperature during control periods was 22-23° C. and during the 1 week of heat exposure was 32-35° C. Lights were on from 6 A.M. to 8 P.M. (14 hr. light, 10 hr. dark). Food and water were available ad libitum. Measurements of Fertility. Five groups of mice were studied: (a) those whose
Adrenal-Gonadal Function in Rats with Frontal Hypothalamic Transections
Neuroendocrinology, 1975
ABSTRACT
Adrenal-Gonadal Relations and Fertility: The Effects of Repeated Stress upon the Adrenal Rhythm
Neuroendocrinology, 1974
ABSTRACT
Brain Research, 1976
The release of various hormones is related to the occurrence of sleep in humans 22. This relation... more The release of various hormones is related to the occurrence of sleep in humans 22. This relationship between sleep and gonadotrophin release is limited to specific periods of changing gonadal function, such as the time of puberty when an augmentation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release occurs during sleep 1. An augmentation of gonadotrophin release also occurs toward the end of the nocturnal sleep period at the time of the LH surge which precedes ovulation during the menstrual cycle 10. In contrast, LH secretion decreases shortly after sleep onset during the follicular phase of the menstrual cycle 10. In the female rat, the alterations in gonadotrophin and ovarian hormone patterns at the time of puberty are similar to those occurring on the day of proestrus during the estrous cycle of the adult6,16. The proestrous period is also associated with quantitative changes in the distribution of sleep-wakefulness states 4. Therefore, the present study was designed to examine the distribution of sleep-wakefulness states during puberty in the female rat. Female Sprague-Dawley rats (Simonsen Laboratories, Gilroy, Calif.) were received at 14 days of age and kept with their mothers in litters of 8 pups on a 14 h: l0 h light/dark schedule until they were weaned at 21 days of age. At 26 days of age, all animals were anesthetized with sodium methohexital (Brevital®, Lilly Pharmaceutical Company; 52 mg/kg body wt.) and electrodes were implanted for recording cortical EEG (parietal lobes), EMG (nuchal musculature) and EKG. The electrode leads were connected to a 9-pin Amphenol plug which was fixed to the skull with dental cement. After surgery, the rats were housed separately in plexiglass cylinders (45 cm diam.) in a quiet recording chamber and maintained on a 12 h:l 2 h light/dark schedule (lights on 09.00 h-21.00 h) with food and water available ad lib. Room temperature ranged between 24 and 26 °C. The Amphenol plugs on the animals were coupled to suspended recording cables and the animals were allowed to adapt to the recording conditions for 6 days before the first recording session at 32 days of age. The physiological signals were amplified (Offner 481B preamplifiers) and recorded on l-in. FM analog tape. Recordings were interrupted only to change the tapes at the beginning of each light or dark period. The data on the analog tapes were later written onto paper using a Grass Model P-78 polygraph. The recordings were divided into successive I-min
Rhythms of Progesterone and Corticosterone After PMS-Induced Puberty: Effects of Ovariectomy
Endocrinology, 1974
ABSTRACT
Precocious Puberty: The Effect of Adrenalectomy on PMSInduced Ovulation and Progesterone Secretion
Endocrinology, 1975
Female Sprague-Dawley derived rats were received at 21 days of age and either sham-operated or ad... more Female Sprague-Dawley derived rats were received at 21 days of age and either sham-operated or adrenalectomized on that day. Half of the animals received either 25 IU pregnant mare's serum gonadotrophin (PMS) or 0.9 saline at 9 AM on the next day; the other half were injected at 26 days of age. On the day of expected ovulation (days 24-25 and days 28-29) the rats were killed at 4-hr intervals and the incidence of ovulation determined. Serum progesterone and corticosterone were measured with the intent of comparing the pattern of these steroids with the timing and incidence of ovulation. Twenty-two-day-old rats given PMS ovulated later (at 0400 on day 25) than did the 26-day-old rats (at 2400 on day 28). Adrenalectomized ADRX rats ovulated later than intact controls at both ages (ovulation complete at 1600 on days 25 and 29, respectively). There was a reduced ovarian weight response to PMS in ADRX rats but uterine weights were not consistently different from intact PMS-treated rats. Associated with the different timing of ovulation and organ weight response in the ADRX rats there was a lower serum progesterone response on days 24-25. In intact PMS-treated rats, the rhythm of the serum corticosterone was different in the two age groups. It is concluded that adrenalectomy alters the normal response to PMS resulting in a delay in the time of ovulation. It is possible that the adrenal normally participates in the induction of ovulation after PMS, possibly by acting as an internal priming agent to facilitate gonadotrophin release in the young rat.
Biology of Reproduction, 1975
Weanling rats were placed in either a 14:10 cycle (LD) or constant light (LL) and were then left ... more Weanling rats were placed in either a 14:10 cycle (LD) or constant light (LL) and were then left intact, sham-operated or adrenalectomized on the following day.
SME Competitiveness Outlook 2020, 2020
First Panel: Balancing Academic Depth and Breadth
Moderated by Maurice Hamington, the panelist discuss the issues of depth versus breadth in education
Collaboration for Student Transfer: A Nationwide Degree Qualifications Profile Experiment
Letter to the Editor 6
Change: The Magazine of Higher Learning, 2010
The Organization That Changes Itself: Innovation for a New Era
ABSTRACT
The national perspective: Fostering the enhancement of STEM undergraduate education
New Directions for Teaching and Learning, 2009
ABSTRACT This chapter considers how best to integrate STEM education into the larger context of t... more ABSTRACT This chapter considers how best to integrate STEM education into the larger context of the undergraduate experience to address important national concerns.
The Effect of an Acute Light Cycle Change on Adrenal Rhythmicity in Prepubertal Rats
Neuroendocrinology, 1975
24 and 28 day old rats, raised in a 14 h light: 10 h dark (14:10) cycle, showed a clear serum cor... more 24 and 28 day old rats, raised in a 14 h light: 10 h dark (14:10) cycle, showed a clear serum corticosterone (B) peak at the beginning of the dark period (18.00 h) with an amplitude of 25-30 mug%. Other B values during the 24 h period were lower (9-12 mug%). Rats raised in a 8.5:15.5 cycle had a B peak (after onset of the dark period, at 22.00 h). Rats raised in constant light (LL) showed no variation in B throughout the 24 h. Weanling rats raised in a 8.5:15.5 cycle appeared to synchronize more rapidly to a 14:10 cycle than did rats raised in LL. When placed in LL at weaning, rats raised either in 14:10 or 8.5:15.5 had lost their periodicity by day 24. When rats raised in 8.5:15.5 were shifted to LL or 14:10 after weaning age (day 24), the pattern of response was different. One day after the shift, rats placed in a 14:10 cycle displayed a pattern of B synchronized to the normal 14:10 pattern for rats born and raised in that light cycle. This synchrony persisted for at least 3 days. Rats placed in 14:10 at 21 days of age did not show a fully synchronized pattern until day 28. It can be concluded that weanling rats exposed to a light-dark cycle adapt quickly to a new light cycle and that older prepubertal rats shift even more quickly.
New truths and old verities
New Directions for Higher Education, 2002
An environment for learning should be established that reflects an informed awareness of how peop... more An environment for learning should be established that reflects an informed awareness of how people learn, one that prepares all students for life and work in a society dominated by science and technology and is based on the expectation that all students can learn science and mathematics.
Journal of Higher Education Outreach and Engagement, Sep 26, 2014
The role of higher education is changing in today's world because the world itself is changing, a... more The role of higher education is changing in today's world because the world itself is changing, and complex problems confront us daily. This essay will explore the role of an emerging group of individuals who can serve as a bridge between the academic community and the world at large. These administrators, faculty members, staff, students, and community members can help create new opportunities for different disciplines to work together and for all parts of a campus community and members of the broader society to form new working relationships to address the complex problems of today's world. What role will these boundary spanners play in building a culture of engagement? How will their work change our ideas about faculty work, staff work, and the role of students in achieving the goals of the institution and in responding to the changing world around us?
Metropolitan universities, 2009
Higher education in this country has always been expected to serve the public good. Sometimes, th... more Higher education in this country has always been expected to serve the public good. Sometimes, the emphasis is on preparing educated citizens or practitioners in especially critical fields and how public service can deepen and enrich learning and prepare students to lead purposeful, responsible, and creative lives. Sometimes the focus is upon institutions themselves as major intellectual and cultural resources for a community. In this paper, based on the keynote presentation at the Community Engaged Scholarship for Health Collaborative's invitational symposium, the author explores four levels ofengagement: the individual, the academic community and its concepts ofscholarship, the institution and its relationships with its immediate community, and the role ofhigher education within a large network of interactions that define a region of innovation.
Fertility and Sterility, 1973
Although the effects of cold stress l and long-term 2, 3 or intermittent 4 , 5 heat stress upon f... more Although the effects of cold stress l and long-term 2, 3 or intermittent 4 , 5 heat stress upon fertility have been reported, little is known about the effect of a short-term, continuous heat exposure upon sexual maturation and subsequent fertility in prepubertal mice. In the study reported here, female C57/B16 mice were exposed to heat for 1 week during various stages of gestation and lactation, and their offspring were followed for several weeks thereafter in order to determine growth rates, survival rates, age at vaginal opening, vaginal cyclicity, percentage fertility, and length of conception time after exposure to males. MATERIALS AND METHODS Animals. Male and female C57/B16 mice of breeding age were obtained from Murphy Farms, Plainfield, Indiana. The mice were kept in disposable transparent plastic cages (dimensions: 7~ inches x 11~ inches) lined with Absorb-DriR litter, three females with litters plus one male per box or five females without litters plus one male per box. Ambient temperature during control periods was 22-23° C. and during the 1 week of heat exposure was 32-35° C. Lights were on from 6 A.M. to 8 P.M. (14 hr. light, 10 hr. dark). Food and water were available ad libitum. Measurements of Fertility. Five groups of mice were studied: (a) those whose
Adrenal-Gonadal Function in Rats with Frontal Hypothalamic Transections
Neuroendocrinology, 1975
ABSTRACT
Adrenal-Gonadal Relations and Fertility: The Effects of Repeated Stress upon the Adrenal Rhythm
Neuroendocrinology, 1974
ABSTRACT
Brain Research, 1976
The release of various hormones is related to the occurrence of sleep in humans 22. This relation... more The release of various hormones is related to the occurrence of sleep in humans 22. This relationship between sleep and gonadotrophin release is limited to specific periods of changing gonadal function, such as the time of puberty when an augmentation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release occurs during sleep 1. An augmentation of gonadotrophin release also occurs toward the end of the nocturnal sleep period at the time of the LH surge which precedes ovulation during the menstrual cycle 10. In contrast, LH secretion decreases shortly after sleep onset during the follicular phase of the menstrual cycle 10. In the female rat, the alterations in gonadotrophin and ovarian hormone patterns at the time of puberty are similar to those occurring on the day of proestrus during the estrous cycle of the adult6,16. The proestrous period is also associated with quantitative changes in the distribution of sleep-wakefulness states 4. Therefore, the present study was designed to examine the distribution of sleep-wakefulness states during puberty in the female rat. Female Sprague-Dawley rats (Simonsen Laboratories, Gilroy, Calif.) were received at 14 days of age and kept with their mothers in litters of 8 pups on a 14 h: l0 h light/dark schedule until they were weaned at 21 days of age. At 26 days of age, all animals were anesthetized with sodium methohexital (Brevital®, Lilly Pharmaceutical Company; 52 mg/kg body wt.) and electrodes were implanted for recording cortical EEG (parietal lobes), EMG (nuchal musculature) and EKG. The electrode leads were connected to a 9-pin Amphenol plug which was fixed to the skull with dental cement. After surgery, the rats were housed separately in plexiglass cylinders (45 cm diam.) in a quiet recording chamber and maintained on a 12 h:l 2 h light/dark schedule (lights on 09.00 h-21.00 h) with food and water available ad lib. Room temperature ranged between 24 and 26 °C. The Amphenol plugs on the animals were coupled to suspended recording cables and the animals were allowed to adapt to the recording conditions for 6 days before the first recording session at 32 days of age. The physiological signals were amplified (Offner 481B preamplifiers) and recorded on l-in. FM analog tape. Recordings were interrupted only to change the tapes at the beginning of each light or dark period. The data on the analog tapes were later written onto paper using a Grass Model P-78 polygraph. The recordings were divided into successive I-min
Rhythms of Progesterone and Corticosterone After PMS-Induced Puberty: Effects of Ovariectomy
Endocrinology, 1974
ABSTRACT
Precocious Puberty: The Effect of Adrenalectomy on PMSInduced Ovulation and Progesterone Secretion
Endocrinology, 1975
Female Sprague-Dawley derived rats were received at 21 days of age and either sham-operated or ad... more Female Sprague-Dawley derived rats were received at 21 days of age and either sham-operated or adrenalectomized on that day. Half of the animals received either 25 IU pregnant mare's serum gonadotrophin (PMS) or 0.9 saline at 9 AM on the next day; the other half were injected at 26 days of age. On the day of expected ovulation (days 24-25 and days 28-29) the rats were killed at 4-hr intervals and the incidence of ovulation determined. Serum progesterone and corticosterone were measured with the intent of comparing the pattern of these steroids with the timing and incidence of ovulation. Twenty-two-day-old rats given PMS ovulated later (at 0400 on day 25) than did the 26-day-old rats (at 2400 on day 28). Adrenalectomized ADRX rats ovulated later than intact controls at both ages (ovulation complete at 1600 on days 25 and 29, respectively). There was a reduced ovarian weight response to PMS in ADRX rats but uterine weights were not consistently different from intact PMS-treated rats. Associated with the different timing of ovulation and organ weight response in the ADRX rats there was a lower serum progesterone response on days 24-25. In intact PMS-treated rats, the rhythm of the serum corticosterone was different in the two age groups. It is concluded that adrenalectomy alters the normal response to PMS resulting in a delay in the time of ovulation. It is possible that the adrenal normally participates in the induction of ovulation after PMS, possibly by acting as an internal priming agent to facilitate gonadotrophin release in the young rat.
Biology of Reproduction, 1975
Weanling rats were placed in either a 14:10 cycle (LD) or constant light (LL) and were then left ... more Weanling rats were placed in either a 14:10 cycle (LD) or constant light (LL) and were then left intact, sham-operated or adrenalectomized on the following day.
SME Competitiveness Outlook 2020, 2020
First Panel: Balancing Academic Depth and Breadth
Moderated by Maurice Hamington, the panelist discuss the issues of depth versus breadth in education
Collaboration for Student Transfer: A Nationwide Degree Qualifications Profile Experiment
Letter to the Editor 6
Change: The Magazine of Higher Learning, 2010
The Organization That Changes Itself: Innovation for a New Era
ABSTRACT
The national perspective: Fostering the enhancement of STEM undergraduate education
New Directions for Teaching and Learning, 2009
ABSTRACT This chapter considers how best to integrate STEM education into the larger context of t... more ABSTRACT This chapter considers how best to integrate STEM education into the larger context of the undergraduate experience to address important national concerns.
The Effect of an Acute Light Cycle Change on Adrenal Rhythmicity in Prepubertal Rats
Neuroendocrinology, 1975
24 and 28 day old rats, raised in a 14 h light: 10 h dark (14:10) cycle, showed a clear serum cor... more 24 and 28 day old rats, raised in a 14 h light: 10 h dark (14:10) cycle, showed a clear serum corticosterone (B) peak at the beginning of the dark period (18.00 h) with an amplitude of 25-30 mug%. Other B values during the 24 h period were lower (9-12 mug%). Rats raised in a 8.5:15.5 cycle had a B peak (after onset of the dark period, at 22.00 h). Rats raised in constant light (LL) showed no variation in B throughout the 24 h. Weanling rats raised in a 8.5:15.5 cycle appeared to synchronize more rapidly to a 14:10 cycle than did rats raised in LL. When placed in LL at weaning, rats raised either in 14:10 or 8.5:15.5 had lost their periodicity by day 24. When rats raised in 8.5:15.5 were shifted to LL or 14:10 after weaning age (day 24), the pattern of response was different. One day after the shift, rats placed in a 14:10 cycle displayed a pattern of B synchronized to the normal 14:10 pattern for rats born and raised in that light cycle. This synchrony persisted for at least 3 days. Rats placed in 14:10 at 21 days of age did not show a fully synchronized pattern until day 28. It can be concluded that weanling rats exposed to a light-dark cycle adapt quickly to a new light cycle and that older prepubertal rats shift even more quickly.