Julio Manuel Gómez Ochoa - Academia.edu (original) (raw)

Papers by Julio Manuel Gómez Ochoa

EDULEARN Proceedings, 2020

EDULEARN Proceedings, 2021

EDULEARN Proceedings, 2020

EDULEARN proceedings, 2017

Information in its multiple forms (oral, textual, hypertextual, audio, video, iconic, multimedia ... more Information in its multiple forms (oral, textual, hypertextual, audio, video, iconic, multimedia ...) is the raw material of the current era. The development and evolution of our civilization is symbiotically linked to the Information and communications technology (ICT). Proposals for teaching and learning in the context of the knowledge society must integrate an educational system that target the thought operations, not only under the traditional logical thinking, but also within a model where thought operations can be expressed in complex active competences, in which abstract knowledge is mixed with the experiential, defined as technological thinking. Currently, the use of devices such as smartphones and tablets is widespread in the youth and the University community. This development reflects not only the growing penetration of these devices in the academic environment, but also that technological applications are increasingly commonly incorporated, which can be used for professors with academic purposes. Currently, there is software available that allows designing and developing applications for smartphones and tablets with academic content. In our case, we intend to design an academic app for Android and iOS systems, which can facilitate the study of various subjects through seamless student-professor communication. The subjects to which the app is addressed include complex physiological phenomena, cell exchange processes and inter-chamber interactions. The lack of time to deal with many contents and concepts is a major problem for professors when it comes to developing the subject, and they are overwhelmed by an enormous amount of information. In this context, the app can lead to a profound change in the subject teaching. This represents a huge challenge for professors, related to innovation, technology, science and education. Tablets, smartphones and applications will be increasingly present in everyday life including university classrooms. Therefore it is imperative that professors have a motivated attitude to the use of these tools and they should be specially trained in its use to develop appropriate educational activities. Knowing devices, products, resources for selection, content is essential to maximize the potential of technology in teaching.

Journal of Physiology and Biochemistry, 2022

COVID-19, an acute respiratory disease caused by SARS-CoV-2, has rapidly become a pandemic. On th... more COVID-19, an acute respiratory disease caused by SARS-CoV-2, has rapidly become a pandemic. On the other hand, obesity is also reaching dramatic dimensions and it is a risk factor for morbidity and premature mortality. Obesity has been linked to a high risk of serious-associated complications to COVID-19, due to the increased risk of concomitant chronic diseases, which highlights the health public relevance of the topic. Obese subjects have a pro-inflammatory environment, which can further exacerbate COVID-19-induced inflammation and oxidative stress, explaining the increased risk of serious complications in these patients. Another factor that favors infection in obese patients is the high expression of ACE2 receptors in the adipose tissue. The negative impact of COVID-19 in obesity is also associated with a decrease in respiratory function, the concurrence of multiple comorbidities, a low-degree chronic inflammatory state, immunocompromised situation, and therefore a higher rate of hospitalization, mechanical ventilation, in-hospital complications such as pneumonia, and death. In this review, the link between obesity and COVID-19 was analyzed, exploring the potential common mechanisms in both diseases, with special attention to oxidative stress and inflammation, due to the crucial role of both pathways in the development of the disease.

La realizacion del presente estudio analitico ha tenido como principal objetivo ampliar y mejorar... more La realizacion del presente estudio analitico ha tenido como principal objetivo ampliar y mejorar los datos queactualmente vienen reflejados en las tablas de composicion de alimentos espanoles, aportando datos que, ademas depropios, corresponden a alimentos ampliamente distribuidos en el mercado espanol y son consumidos de formahabitual en nuestro pais. El analisis de los diferentes minerales se ha realizado en 28 alimentos precocinados congelados,previamente seleccionados, entre los que se incluyen pastas, pizzas, arroces y fritos de mayor consumo. Estetipo de alimentos son susceptibles de sufrir perdidas en minerales debido a los procesos de elaboracion, congelaciony pretratamiento culinario a que son sometidos antes de su consumo, por lo que es de gran interes el conocimientode su composicion mineral, dando respuesta a las exigencias de un amplio grupo de profesionales y consumidoresque requieren de esta informacion nutricional.

EDULEARN21 Proceedings, 2021

Food & Function, 2020

Bone and energy metabolism are profoundly influenced by exercise.

Universidad Colegio Mayor Nuestra Senora Del Rosario Universidad Del Rosario Edocur Repositorio Institucional Disponible En Http Repository Urosario Edu Co, Jul 11, 2014

Revista Mexicana De Biodiversidad, Feb 19, 2014

Cienc Tecnol Salud Vis Ocul, Dec 1, 2010

Objetivo: determinar la prevalencia de defectos refractivos y patologias oculares en pacientes ge... more Objetivo: determinar la prevalencia de defectos refractivos y patologias oculares en pacientes geriatricos de Bogota, atendidos entre octubre de 2007 y septiembre de 2008. Metodologia: con el apoyo de la Clinica de Optometria de la Universidad de La Salle, se estudiaron 596 pacientes pertenecientes al Hogar de Ancianos Casa Nostra, Hogar Santa Teresa de Jornet, Hogar Sagrado Corazon, Despertar Balcanes, Bosque Popular y Bello Horizonte, de la Secretaria de Integracion Social del Distrito Capital. A todos los pacientes se les realizo examen clinico optometrico: agudeza visual en V.L., agudeza visual en V.P., toma de distancia pupilar, examen externo, oftalmoscopia sin dilatacion, presion intraocular, rejilla de Amsler, queratometria y retinoscopia. Para la determinacion de retinopatia hipertensiva, se utilizo la clasificacion de Keith-Wagener-Berker, y de acuerdo al ETDRS se diferencio la retinopatia diabetica, previa estandarizacion de la prueba y consentimiento informado. La informacion se recolecto en el formato de historia clinica HCIIO01 VERSION 006-2007. Se utilizo la base de datos en el programa EPI INFO 6.4 y se realizo analisis estadistico descriptivo. Resultados: el defecto refractivo con mayor prevalencia fue el astigmatismo, con 36,4%, y la patologia mas prevalente fue el pterigio, con 44,79%. Conclusiones: tanto el astigmatismo como el pterigio son las alteraciones visuales y oculares mas prevalentes en las personas adultas de los hogares estudiados. Con los datos anteriores es importante sugerir la creacion de un modelo de atencion primaria que contemple aspectos educativos, promocionales y asistenciales para este grupo de pacientes, con el animo de intervenir las causas de morbilidad visual y ocular, mejorando la calidad de vida de esta poblacion

INTED2016 Proceedings, 2016

Journal of Functional Foods, 2015

Abstract The effect of maternal DHA supplementation on expression of key genes and proteins invol... more Abstract The effect of maternal DHA supplementation on expression of key genes and proteins involved in Fe metabolism and mineral placenta content was evaluated for the first time. One hundred and ten pregnant women were randomly assigned to one of the groups: control (n = 54, 400 ml/day of the control dairy drink; DHA-supplemented (n = 56, 400 ml/day of the DHA-enriched dairy drink). Placenta DMT1, FPN1, TfR1 and Hamp1 mRNA and protein expressions were analysed. Hepcidin concentration in the mother and umbilical cord and placenta mineral content were assessed. DMT1, FPN1, TfR1 and Hamp1 gene expressions together with serum hepcidin increased in umbilical cord and artery of the DHA-supplemented group. In this group, Fe concentration increased in plasma, umbilical cord vein and artery. Ca concentrations raised in umbilical cord vein and artery, Cu, V and Mn levels. Docosahexaenoic acid (DHA) supplementation improved transplacental Fe homeostasis, enhancing Fe transfer and boosting neonates Fe stores at delivery.

Revista Andaluza de Medicina del Deporte

ABSTRACT Export Date: 18 October 2014

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2015

An age-dependent model of the periodontium was reproduced to evaluate the effect of lifelong feed... more An age-dependent model of the periodontium was reproduced to evaluate the effect of lifelong feeding on a low coenzyme Q 10 dosage in n-6, n-3 polyunsaturated fatty acid or monounsaturated fatty acid-based diets on periodontal tissues of young and old rats. Results shown that exacerbated age-related alveolar bone loss previously associated to n-6 polyunsaturated fatty acid diet was attenuated by coenzyme Q 10. Gene expression analysis suggests that involved mechanisms might be related to a restored capacity of mitochondria to adapt to aging in gingival cells from rats fed on n-6 polyunsaturated fatty acid. In particular, this could be due to an age-related increase of the rate of mitochondrial biogenesis and a better oxidative and respiratory balance in these animals. From the nutritional and clinical point of view, it is noteworthy that supplementation with coenzyme Q 10 could counteract the negative effects of n-6 polyunsaturated fatty acid on alveolar bone loss (a major feature of periodontitis) associated to age.

Journal of Pediatric Gastroenterology & Nutrition, 2015

Objectives: The aim of the present study was to elucidate whether a dairy drink enriched with v-3... more Objectives: The aim of the present study was to elucidate whether a dairy drink enriched with v-3 long-chain polyunsaturated fatty acid (LC-PUFA) could have an impact on the lipid profile of the mother and the newborn, and also whether this intervention could affect the newborns' visual and cognitive development. Methods: A total of 110 pregnant women were randomly assigned to one of the following intervention groups: control group (n ¼ 54), taking 400 mL/ day of the control dairy drink, and supplemented group (fish oil [FO]) (n ¼ 56), taking 400 mL/day of the fish oil-enriched dairy drink (including $400 mg eicosapentaenoic acid-docosahexaenoic acid [DHA]/day). During the study, the mothers' diets were supervised by a nutritionist to encourage compliance with present recommendations of FA intake. Blood fatty acid profiles were determined in the mother's (at enrollment, at delivery, and at 2.5 and 4 months) and newborn (at delivery and at 2.5 months) placenta and breast milk (colostrum and at 1, 2, and 4 months). Pattern reversal visual evoked potentials (VEPs) (at 2.5 and 7.5 months) and Bayley test (at 12 months) were recorded. Results: DHA percentage was higher in plasma, erythrocyte membranes, and breast milk samples from the FO group. The ratio of nervonic acid was also higher in plasma and erythrocyte lipids of the mother and newborn's blood samples from the FO group. No differences were observed in the Bayley test. No differences were observed in VEPs between both groups. We observed a shorter latency, however, in the lower visual angle (7.5 0) in the boys of the supplemented group. Conclusions: Omega-3 LC-PUFA dietary supplement during pregnancy and lactation influenced the mother and newborn's fatty acid profile and nervonic acid content but did not show effects on visual and cognitive/psychomotor development.

Nutrition, metabolism, and cardiovascular diseases : NMCD, 1999

The effects of four edible oils on lipid peroxidation have been investigated in rabbit heart mito... more The effects of four edible oils on lipid peroxidation have been investigated in rabbit heart mitochondrial membranes. The experimental oils (olive oil from the variety "picual", washed olive oil from the variety "picual", olive oil from the variety "arbequina" and high-oleic sunflower oil) had a similar fatty-acid composition, but differed in their unsaponified fraction (polyphenols, tocopherols, and others). The lowest hydroperoxide levels were found with picual and washed picual. No differences in mitochondrial membrane thiobarbituric acid reactive substance (TBARS), alpha-tocopherol concentrations and cytosolic antioxidant enzymes (superoxide dismutase, glutathione peroxidase, glutathione reductase and catalase) were found, whereas the CoQ10 content correlated inversely with hydroperoxide levels in all groups. These results suggest that mitochondrial membranes with high levels of monounsaturated fatty acids generate low levels of lipid peroxidation. ...

International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition, 1996

Two four-day diet records were used to estimate usual energy and nutrient intake, eating patterns... more Two four-day diet records were used to estimate usual energy and nutrient intake, eating patterns (habits) and contribution of meals to total energy intake, in a group of 92 biology students from the Granada University. At the same time, a series of anthropometric measures was taken from each subject (weight, height, skin pleats and arm measurement). Comparison of real intakes with those recommended was carried out using the 1980 Spanish recommendations and the 1992 European Community recommendations. For men (n = 42) mean intakes for most nutrients were similar to the recommended levels and the proportion with intakes of vitamins and minerals below 80% of the recommended intakes was also minimal. Among women (n = 50) mean intake of zinc was below 80% of the Spanish recommendation. However, there was a wide range of intakes of minerals and vitamins within both groups; therefore, we found a high percentage of subjects with intakes of some vitamins or minerals below 80% of the recomme...

EDULEARN Proceedings, 2020

EDULEARN Proceedings, 2021

EDULEARN Proceedings, 2020

EDULEARN proceedings, 2017

Information in its multiple forms (oral, textual, hypertextual, audio, video, iconic, multimedia ... more Information in its multiple forms (oral, textual, hypertextual, audio, video, iconic, multimedia ...) is the raw material of the current era. The development and evolution of our civilization is symbiotically linked to the Information and communications technology (ICT). Proposals for teaching and learning in the context of the knowledge society must integrate an educational system that target the thought operations, not only under the traditional logical thinking, but also within a model where thought operations can be expressed in complex active competences, in which abstract knowledge is mixed with the experiential, defined as technological thinking. Currently, the use of devices such as smartphones and tablets is widespread in the youth and the University community. This development reflects not only the growing penetration of these devices in the academic environment, but also that technological applications are increasingly commonly incorporated, which can be used for professors with academic purposes. Currently, there is software available that allows designing and developing applications for smartphones and tablets with academic content. In our case, we intend to design an academic app for Android and iOS systems, which can facilitate the study of various subjects through seamless student-professor communication. The subjects to which the app is addressed include complex physiological phenomena, cell exchange processes and inter-chamber interactions. The lack of time to deal with many contents and concepts is a major problem for professors when it comes to developing the subject, and they are overwhelmed by an enormous amount of information. In this context, the app can lead to a profound change in the subject teaching. This represents a huge challenge for professors, related to innovation, technology, science and education. Tablets, smartphones and applications will be increasingly present in everyday life including university classrooms. Therefore it is imperative that professors have a motivated attitude to the use of these tools and they should be specially trained in its use to develop appropriate educational activities. Knowing devices, products, resources for selection, content is essential to maximize the potential of technology in teaching.

Journal of Physiology and Biochemistry, 2022

COVID-19, an acute respiratory disease caused by SARS-CoV-2, has rapidly become a pandemic. On th... more COVID-19, an acute respiratory disease caused by SARS-CoV-2, has rapidly become a pandemic. On the other hand, obesity is also reaching dramatic dimensions and it is a risk factor for morbidity and premature mortality. Obesity has been linked to a high risk of serious-associated complications to COVID-19, due to the increased risk of concomitant chronic diseases, which highlights the health public relevance of the topic. Obese subjects have a pro-inflammatory environment, which can further exacerbate COVID-19-induced inflammation and oxidative stress, explaining the increased risk of serious complications in these patients. Another factor that favors infection in obese patients is the high expression of ACE2 receptors in the adipose tissue. The negative impact of COVID-19 in obesity is also associated with a decrease in respiratory function, the concurrence of multiple comorbidities, a low-degree chronic inflammatory state, immunocompromised situation, and therefore a higher rate of hospitalization, mechanical ventilation, in-hospital complications such as pneumonia, and death. In this review, the link between obesity and COVID-19 was analyzed, exploring the potential common mechanisms in both diseases, with special attention to oxidative stress and inflammation, due to the crucial role of both pathways in the development of the disease.

La realizacion del presente estudio analitico ha tenido como principal objetivo ampliar y mejorar... more La realizacion del presente estudio analitico ha tenido como principal objetivo ampliar y mejorar los datos queactualmente vienen reflejados en las tablas de composicion de alimentos espanoles, aportando datos que, ademas depropios, corresponden a alimentos ampliamente distribuidos en el mercado espanol y son consumidos de formahabitual en nuestro pais. El analisis de los diferentes minerales se ha realizado en 28 alimentos precocinados congelados,previamente seleccionados, entre los que se incluyen pastas, pizzas, arroces y fritos de mayor consumo. Estetipo de alimentos son susceptibles de sufrir perdidas en minerales debido a los procesos de elaboracion, congelaciony pretratamiento culinario a que son sometidos antes de su consumo, por lo que es de gran interes el conocimientode su composicion mineral, dando respuesta a las exigencias de un amplio grupo de profesionales y consumidoresque requieren de esta informacion nutricional.

EDULEARN21 Proceedings, 2021

Food & Function, 2020

Bone and energy metabolism are profoundly influenced by exercise.

Universidad Colegio Mayor Nuestra Senora Del Rosario Universidad Del Rosario Edocur Repositorio Institucional Disponible En Http Repository Urosario Edu Co, Jul 11, 2014

Revista Mexicana De Biodiversidad, Feb 19, 2014

Cienc Tecnol Salud Vis Ocul, Dec 1, 2010

Objetivo: determinar la prevalencia de defectos refractivos y patologias oculares en pacientes ge... more Objetivo: determinar la prevalencia de defectos refractivos y patologias oculares en pacientes geriatricos de Bogota, atendidos entre octubre de 2007 y septiembre de 2008. Metodologia: con el apoyo de la Clinica de Optometria de la Universidad de La Salle, se estudiaron 596 pacientes pertenecientes al Hogar de Ancianos Casa Nostra, Hogar Santa Teresa de Jornet, Hogar Sagrado Corazon, Despertar Balcanes, Bosque Popular y Bello Horizonte, de la Secretaria de Integracion Social del Distrito Capital. A todos los pacientes se les realizo examen clinico optometrico: agudeza visual en V.L., agudeza visual en V.P., toma de distancia pupilar, examen externo, oftalmoscopia sin dilatacion, presion intraocular, rejilla de Amsler, queratometria y retinoscopia. Para la determinacion de retinopatia hipertensiva, se utilizo la clasificacion de Keith-Wagener-Berker, y de acuerdo al ETDRS se diferencio la retinopatia diabetica, previa estandarizacion de la prueba y consentimiento informado. La informacion se recolecto en el formato de historia clinica HCIIO01 VERSION 006-2007. Se utilizo la base de datos en el programa EPI INFO 6.4 y se realizo analisis estadistico descriptivo. Resultados: el defecto refractivo con mayor prevalencia fue el astigmatismo, con 36,4%, y la patologia mas prevalente fue el pterigio, con 44,79%. Conclusiones: tanto el astigmatismo como el pterigio son las alteraciones visuales y oculares mas prevalentes en las personas adultas de los hogares estudiados. Con los datos anteriores es importante sugerir la creacion de un modelo de atencion primaria que contemple aspectos educativos, promocionales y asistenciales para este grupo de pacientes, con el animo de intervenir las causas de morbilidad visual y ocular, mejorando la calidad de vida de esta poblacion

INTED2016 Proceedings, 2016

Journal of Functional Foods, 2015

Abstract The effect of maternal DHA supplementation on expression of key genes and proteins invol... more Abstract The effect of maternal DHA supplementation on expression of key genes and proteins involved in Fe metabolism and mineral placenta content was evaluated for the first time. One hundred and ten pregnant women were randomly assigned to one of the groups: control (n = 54, 400 ml/day of the control dairy drink; DHA-supplemented (n = 56, 400 ml/day of the DHA-enriched dairy drink). Placenta DMT1, FPN1, TfR1 and Hamp1 mRNA and protein expressions were analysed. Hepcidin concentration in the mother and umbilical cord and placenta mineral content were assessed. DMT1, FPN1, TfR1 and Hamp1 gene expressions together with serum hepcidin increased in umbilical cord and artery of the DHA-supplemented group. In this group, Fe concentration increased in plasma, umbilical cord vein and artery. Ca concentrations raised in umbilical cord vein and artery, Cu, V and Mn levels. Docosahexaenoic acid (DHA) supplementation improved transplacental Fe homeostasis, enhancing Fe transfer and boosting neonates Fe stores at delivery.

Revista Andaluza de Medicina del Deporte

ABSTRACT Export Date: 18 October 2014

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2015

An age-dependent model of the periodontium was reproduced to evaluate the effect of lifelong feed... more An age-dependent model of the periodontium was reproduced to evaluate the effect of lifelong feeding on a low coenzyme Q 10 dosage in n-6, n-3 polyunsaturated fatty acid or monounsaturated fatty acid-based diets on periodontal tissues of young and old rats. Results shown that exacerbated age-related alveolar bone loss previously associated to n-6 polyunsaturated fatty acid diet was attenuated by coenzyme Q 10. Gene expression analysis suggests that involved mechanisms might be related to a restored capacity of mitochondria to adapt to aging in gingival cells from rats fed on n-6 polyunsaturated fatty acid. In particular, this could be due to an age-related increase of the rate of mitochondrial biogenesis and a better oxidative and respiratory balance in these animals. From the nutritional and clinical point of view, it is noteworthy that supplementation with coenzyme Q 10 could counteract the negative effects of n-6 polyunsaturated fatty acid on alveolar bone loss (a major feature of periodontitis) associated to age.

Journal of Pediatric Gastroenterology & Nutrition, 2015

Objectives: The aim of the present study was to elucidate whether a dairy drink enriched with v-3... more Objectives: The aim of the present study was to elucidate whether a dairy drink enriched with v-3 long-chain polyunsaturated fatty acid (LC-PUFA) could have an impact on the lipid profile of the mother and the newborn, and also whether this intervention could affect the newborns' visual and cognitive development. Methods: A total of 110 pregnant women were randomly assigned to one of the following intervention groups: control group (n ¼ 54), taking 400 mL/ day of the control dairy drink, and supplemented group (fish oil [FO]) (n ¼ 56), taking 400 mL/day of the fish oil-enriched dairy drink (including $400 mg eicosapentaenoic acid-docosahexaenoic acid [DHA]/day). During the study, the mothers' diets were supervised by a nutritionist to encourage compliance with present recommendations of FA intake. Blood fatty acid profiles were determined in the mother's (at enrollment, at delivery, and at 2.5 and 4 months) and newborn (at delivery and at 2.5 months) placenta and breast milk (colostrum and at 1, 2, and 4 months). Pattern reversal visual evoked potentials (VEPs) (at 2.5 and 7.5 months) and Bayley test (at 12 months) were recorded. Results: DHA percentage was higher in plasma, erythrocyte membranes, and breast milk samples from the FO group. The ratio of nervonic acid was also higher in plasma and erythrocyte lipids of the mother and newborn's blood samples from the FO group. No differences were observed in the Bayley test. No differences were observed in VEPs between both groups. We observed a shorter latency, however, in the lower visual angle (7.5 0) in the boys of the supplemented group. Conclusions: Omega-3 LC-PUFA dietary supplement during pregnancy and lactation influenced the mother and newborn's fatty acid profile and nervonic acid content but did not show effects on visual and cognitive/psychomotor development.

Nutrition, metabolism, and cardiovascular diseases : NMCD, 1999

The effects of four edible oils on lipid peroxidation have been investigated in rabbit heart mito... more The effects of four edible oils on lipid peroxidation have been investigated in rabbit heart mitochondrial membranes. The experimental oils (olive oil from the variety "picual", washed olive oil from the variety "picual", olive oil from the variety "arbequina" and high-oleic sunflower oil) had a similar fatty-acid composition, but differed in their unsaponified fraction (polyphenols, tocopherols, and others). The lowest hydroperoxide levels were found with picual and washed picual. No differences in mitochondrial membrane thiobarbituric acid reactive substance (TBARS), alpha-tocopherol concentrations and cytosolic antioxidant enzymes (superoxide dismutase, glutathione peroxidase, glutathione reductase and catalase) were found, whereas the CoQ10 content correlated inversely with hydroperoxide levels in all groups. These results suggest that mitochondrial membranes with high levels of monounsaturated fatty acids generate low levels of lipid peroxidation. ...

International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition, 1996

Two four-day diet records were used to estimate usual energy and nutrient intake, eating patterns... more Two four-day diet records were used to estimate usual energy and nutrient intake, eating patterns (habits) and contribution of meals to total energy intake, in a group of 92 biology students from the Granada University. At the same time, a series of anthropometric measures was taken from each subject (weight, height, skin pleats and arm measurement). Comparison of real intakes with those recommended was carried out using the 1980 Spanish recommendations and the 1992 European Community recommendations. For men (n = 42) mean intakes for most nutrients were similar to the recommended levels and the proportion with intakes of vitamins and minerals below 80% of the recommended intakes was also minimal. Among women (n = 50) mean intake of zinc was below 80% of the Spanish recommendation. However, there was a wide range of intakes of minerals and vitamins within both groups; therefore, we found a high percentage of subjects with intakes of some vitamins or minerals below 80% of the recomme...