Jungim Han - Academia.edu (original) (raw)

Papers by Jungim Han

We demonstrate an innovative method of PCR product identification that is based on thermal denatu... more We demonstrate an innovative method of PCR product identification that is based on thermal denaturation of PCR product-captured bead using integrated BioFET. Laborious purification and concentration of PCR product were easily carried by capturing the samples on the solid surface like microbeads. When temperature raised upto the denaturation point of PCR product, potential of BioFET is changed by mobile DNA in solution from PCR product-captured beads. By differentiating potential change with respect to temperature change, melting temperature can be determined. In this way, we successfully discriminated three kinds of PCR product using their different melting temperature and improved sensitivity of detection. We expect that proposed method can potentially be used for the identification of multiplex PCR products.

TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference, Jun 1, 2009

ABSTRACT

Journal of Fashion Business, 2011

Textile and clothing in Ancient Egypt have carried long history and tradition. Especially, Egypti... more Textile and clothing in Ancient Egypt have carried long history and tradition. Especially, Egyptian textile culture, created mostly by the Copt, has the originality of weaving technology and the artistic beauty of the weaving motifs, making the textiles comparable to modern textiles. The purpose of this study is to research on the characteristics of Coptic textile designs of ancient Egypt and the tunic, a basic garment made of Coptic textiles, and offer materials for the development of the textiles and designs with artistic values which can be shared in the modern era, not just for the research of the relics of the past. Therefore, this study will follow the historical background of Coptic textiles and the process of the development, and look into the distinct features under the categories of material, colors and motifs. In addition, the tunic and its weaving technology will be explained and this will help understand the originality of Coptic textiles. The scope of this study is lim...

Development of a novel real time micro PCR system ... Yoon-Kyoung Cho*, Jin-Tae Kim, Suhyeon Kim,... more Development of a novel real time micro PCR system ... Yoon-Kyoung Cho*, Jin-Tae Kim, Suhyeon Kim, Kak Namkoong, Kwang W. Oh, Chinsung Park, Youngsun Lee, Young-A Kim, Jungim Han, Heekyun Lim, Kyeong-Sik Ock, Kyutae Yoo, Sanghyo Kim, Jung-Joo Hwang, Y. ...

Physical Chemistry Chemical Physics

Molecular dynamics simulations of nanoscale droplets of cyclopentadienyl barium complexes present... more Molecular dynamics simulations of nanoscale droplets of cyclopentadienyl barium complexes present liquid-like structural and dynamic properties.

This paper presents a rapid micro PCR (polymerase chain reaction) system (GenSpector® Micro PCR) ... more This paper presents a rapid micro PCR (polymerase chain reaction) system (GenSpector® Micro PCR) for the application of Hepatitis B virus (HBV) DNA detection. Silicon micromachining technology has been utilized to miniaturize the conventional PCR system. Each module in the system has been installed with an optic system that makes real time in-situ monitoring possible, as well as a built in computer system complete with user-friendly touch screen access. In addition, newly developed electronic temperature controls have cut down response time, making the system faster than ever before. Also, the system enables one or more operators to apply for qualitative or quantitative PCR. Thus, the GenSpector® Micro PCR system will have various applications in nucleic acid point-of-care-tests.

ACS Applied Materials & Interfaces, 2018

Enhancing the mechanical durability of anti-fingerprint films is critical for its industrial appl... more Enhancing the mechanical durability of anti-fingerprint films is critical for its industrial application on touch-screen devices to withstand friction damage from repeated rubbing in daily usage. Using reactive molecular dynamics simulations, we herein implement adhesion, mechanical, and deposition tests to investigate two durability-determining factors: intrachain and interchain strength, which affect the structural stability of the anti-fingerprint film (perfluoropolyether) on silica. From the intrachain perspective, it is found that the Si-C bond in the polymer chain is the weakest, and therefore prone to dissociation and potentially forming a CO bond. This behavior is demonstrated consistently, regardless of the crosslinking density between polymer chains. For the interchain interaction, increasing the chain length enhances the mechanical properties of the film. Furthermore, the chain deposition test, mimicking the experimental coating process, demonstrates that placing shorter chains first to the surface of silica and then depositing longer chains is an ideal way to improve the interchain interaction in the film structure. The current study reveals a clear pathway to optimizing the configuration of the polymer chain as well as its film structure to prolong the product life of the coated anti-fingerprint film.

TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference, 2007

... Microbiol., Vol. 46, pp. 90-97, 1983. [3] Jimmy D. Cox, Mark S. Curry, Stephen K. Skirboll, P... more ... Microbiol., Vol. 46, pp. 90-97, 1983. [3] Jimmy D. Cox, Mark S. Curry, Stephen K. Skirboll, Paul L Gourley, Darryl Y. Sasaki, Surface passivation of a microfluidic device to glidal cell adhesion: a comparison of hydrophobic and hydrophilic SAM coatings, Biomaterials, Vol. 23, pp. ...

Journal of Membrane Science, 2013

Due to its simple process and low energy consumption, forward osmosis (FO) has gained significant... more Due to its simple process and low energy consumption, forward osmosis (FO) has gained significant attention in the fields of emergency drinks, desalination, landfill leachate treatment, and brine concentration. However, current state-of-the-art reverse osmosis (RO) membranes show relatively low water fluxes in FO processes due to high internal concentration polarization (ICP) and high mass transfer resistance in commercially available microporous support membranes. In this study, carboxylated polysulfones (CPSFs) were synthesized via direct polysulfone (PSF) functionalization and considered as moderately hydrophilic, mechanically stable microporous support membranes. The incorporation of hydrophilic groups into hydrophobic polymer backbones often reduces mechanical strength due to excessive water swelling. However, the mechanical properties of CPSFs (degree of substitution, DS=0.45~0.85) were similar to those of pristine PSF, and they retained their hydrophilic nature. Microporous CPSF membranes were prepared in various conditions, and FO water fluxes and salt passages of polyamide thin-film/CPSF composite membranes were measured and compared with each other. CPSF-based FO membranes showed significantly higher water fluxes than PSF-based FO membranes at the same membrane formation conditions, which might be due to enhanced hydrophilicity and reduced ICP.

Biosensors and Bioelectronics, 2006

The polymerase chain reaction (PCR) is widely used to amplify a small amount of DNA in samples fo... more The polymerase chain reaction (PCR) is widely used to amplify a small amount of DNA in samples for genetic analysis. Rapid and accurate amplification is prerequisite for broad applications including molecular diagnostics of diseases, food safety, and biological warfare tests. We have developed a rapid real-time micro-scale chip-based PCR system, which consists of six individual thermal cycling modules capable of independent control of PCR protocols. The PCR volume is 1 l and it takes less than 20 min to complete 40 thermal cycles. To test utility of a chip-based PCR system as a molecular diagnostic device, we have conducted the first large-scale clinical evaluation study. Three independent clinical evaluation studies (n = 563) for screening the hepatitis B virus (HBV) infection, the most popular social epidemic disease in Asia, showed an excellent sensitivity, e.g. 94%, and specificity, e.g. 93%, demonstrating micro-scale chip-based PCR can be applied in molecular diagnostics.