K Santhosh kumar - Academia.edu (original) (raw)

Papers by K Santhosh kumar

Chemical Science, 2021

Synthetic alpha-helix based pores for selective sensing of peptides have not been characterized p... more Synthetic alpha-helix based pores for selective sensing of peptides have not been characterized previously.

Health Information Science, 2021

With the development of database systems and networking technologies, Hospital Information Manage... more With the development of database systems and networking technologies, Hospital Information Management Systems (HIMS) and web-based clinical or medical systems (such as the Medical Director, a generic GP clinical system) are widely used in health and clinical practices. Healthcare and medical service are more dataintensive and evidence-based since electronic health records are now used to track individuals' and communities' health information. These highlights substantially motivate and advance the emergence and the progress of health informatics research and practice. Health Informatics continues to gain interest from both academia and health industries. The significant initiatives of using information, knowledge and communication technologies in health industries ensures patient safety, improve population health and facilitate the delivery of government healthcare services. Books in the series will reflect technology's cross-disciplinary research in IT and health/medical science to assist in disease diagnoses, treatment, prediction and monitoring through the modeling, design, development, visualization, integration and management of health related information. These technologies include information systems, web technologies, data mining, image processing, user interaction and interfaces, sensors and wireless networking, and are applicable to a wide range of health-related information such as medical data, biomedical data, bioinformatics data, and public health data.

The use of organic fertilizer and insecticides forms the backbone & basic necessity of a poor far... more The use of organic fertilizer and insecticides forms the backbone & basic necessity of a poor farmer. The traditional methods of using chemical fertilizers and insecticides are not sufficient & satisfactory for increasing productivity of crop and to maintain the fertility of soil. Farmers use chemical fertilizers for growth of their crops. But there are many disadvantages to the crops if chemical fertilizers are applied to the soil. To reduce the efforts of farmer in preparing the organic mixture, by designing a low budget organic fertilizer and insecticides making machine. Whereas the chemical fertilizers are more costly in market, so it becomes difficult for poor farmers to purchase it. Organic fertilizer and insecticides manufacturing machine solves these both problems.

International Research Journal of Multidisciplinary Studies, 2016

Water scarcity is one of the major problem facing major cities of the world. Major problems regar... more Water scarcity is one of the major problem facing major cities of the world. Major problems regarding that are when either sump or bore well motor is started people forget to switch OFF these motors so water goes waste as well as electricity gets consumed. There is not fix schedule to start and stop motors so there is always problem of unwanted vacancy of water in overhead tank, people are facing such problems at midnight & situation becomes critical. Sumps as well as bore well motor can dry run giving electricity wastage. So overall wastage has been identified as a major culprit; this is one of the motivations for this research, to deploy computing techniques in creating a barrier to wastage in order to not only provide more financial gains and energy saving, but also help the environment and water cycle which in turn ensures that water is saved for our future. This paper presents research in embedding a control system into an automatic water pump controller through the use of diff...

International Research Journal of Multidisciplinary Technovation, 2020

An orphanage is a residential institution devoted to the care of orphan-children whose parents ar... more An orphanage is a residential institution devoted to the care of orphan-children whose parents are unwilling or unable to take care of them. The problem of orphan is acute due to urbanization and industrialization. Need for each of the orphanages varies in different categories such as food, money, clothes, medicine. Most of the people would like to help the orphanages but the major problem is that they have any idea on how to approach these orphanages. The main objective of this application is to develop a centralized site for orphanages. In our proposed system we try to create an interface between Orphanages\Old age Homes which are in need of charity and people/Volunteers who are willing to help these people. Volunteers can also approach the Orphanage managers regarding the help that they can afford. People can donate through Internet Banking or Online Money Payment applications.

Materials Today: Proceedings, 2021

Abstract Carbon nanotubes (CNT) are an outstanding development in the field of nanostructure. Uni... more Abstract Carbon nanotubes (CNT) are an outstanding development in the field of nanostructure. Unique characteristics of Carbon Nanotubes (CNT) make them a suitable reinforcing agent in Aluminium Metal Matrix composites. These composites are being anticipated in aviation for their high explicit quality just as utilitarian materials for their energizing mechanical and warm attributes. The property of carbon nanotube strengthened aluminum network (Al-CNT) composites mainly depends on the percentage weight of reinforced material in the base material. Thus the main objective of this review paper to addresses the concentration of CNT on tensile strength, yield strength and compressive strength of CNT - Al matrix composites.

Materials Today: Proceedings, 2021

Abstract In this study, AA5083 plates were friction stir processed to improve the hardness by ref... more Abstract In this study, AA5083 plates were friction stir processed to improve the hardness by refining the grains and dispersing the β phase in the matrix. Tool rotation speed, tool traverse speed, and tool shoulder diameter were varied as per the face-centered central composite design and FSP trials were performed. The wear resistance of the friction stir processed specimens was estimated by conducting a wear test using a pin-on-disc tribometer. It was observed that the wear resistance was higher than the base specimens and TRS, TTS and SD had a significant effect on the wear resistance. An artificial neural network model and a fuzzy logic model were developed to predict the wear resistance of the friction stir processed specimens. As the Sugeno Fuzzy model had greater prediction efficiency than the ANN model, it was used to study the effect of FSP process parameters on the wear resistance of the specimens. The results indicate that a TRS of 1000 rpm, TTS of 30 mm/min, and SD of 18 mm maximized the wear resistance of the processed plate to 8820 N-m/kg.

Research Journal of Engineering and Technology, 2019

ECS Journal of Solid State Science and Technology, 2016

1ST INTERNATIONAL CONFERENCE ON MANUFACTURING, MATERIAL SCIENCE AND ENGINEERING (ICMMSE-2019), 2019

Steering is the group of parts with joints which allows any vehicle to follow the required path. ... more Steering is the group of parts with joints which allows any vehicle to follow the required path. The traditional steering mechanism is to turn the front wheels using steering wheel with the help of steering columns and universal joints, to allow it to turn away to some extent from a straight line. The steering system must give a mechanical dominance over front wheel steering knuckles, contributing driver an effortless turning of front wheels in desired direction. The steering system is designed to withstand the stress of safely maneuvering the vehicle through any type of driving condition by continuously adjust the steered path of the vehicle. The steering system is to provides directional control of the vehicle with minimum input. In our project, the Ackermann steering system is designed for a go-kart. After designing the steering system, the Later simulation model of design is constructed for ensuring performance optimization, safety engineering for real-time conditions. A simulation is an operation of a real-world process done using workstation. By using simulation, a model can be embedded with multiple variations. These are capable of performing analysis and understanding of how single or multiple elements react to the simulated environment. The platform selected for the simulation process is SOLID WORKS software.The final stage of this project is structural fabrication of the steering system based on our design and complete analysis. The material appropriate for creation of this system is mild steel, its price is low while it facilitates material properties that are sustainable for many applications. Main point is its strength to weight ratio which is very advantage when compared to all steels. The objective of present work is to provide a robust steering system, with high performance for a Go-Kart vehicle.

Materials Chemistry and Physics, 2019

In this work, we have synthesized a series of nanocomposites of few layered defective graphene ox... more In this work, we have synthesized a series of nanocomposites of few layered defective graphene oxide (GO) and mesoporous SiO 2 , and studied their frequency (1-10MHz) and temperature (50-400 o C) dependent dielectric properties. We have tuned the surface area and pore size of mesoporous SiO 2 and conjugated the mover the GO sheets to achieve new hybrid nanocomposites. The formation of conjugation has been confirmed through microscopy and spectroscopy studies. Impedance spectroscopy indicated a very high dielectric constant for the novel composites that was found to being the range of 7.961 x 10 5 to 2.191 x 10 3 and 2.790 x 10 8 to 2.770 x 10 4 at the frequencies of 1Hz and 10 kHz at 50 o C and 400 o C, respectively. Such increase in the dielectric constants is attributed to the formation of chemical conjugation on the GO with mesoporous SiO 2 which results due to change in the orientation and space charge polarization as well as the porous behavior of the composites studied at different conditions. Temperature and frequency dependent dc and ac conductivities have also been calculated through the impedance analysis. They were found to be c.a. 0.000 to 0.25 x 10-3 S/m and 0.007 to 0.120 S/m, respectively, irrespective of the frequency and temperature for the best composite. We show a very simple and cost effective synthesis in the present study. Further, we engineered new novel new nano composites those display high dielectric constant, by utilizing this approach. Thus, this simple approach can be exploited to tune the desired properties of nanocomposites those can be used in various electronic devices.

Indian journal of dental research : official publication of Indian Society for Dental Research

Angiokeratoma is a benign cutaneous lesion of capillaries. It is characterized by large dilated b... more Angiokeratoma is a benign cutaneous lesion of capillaries. It is characterized by large dilated blood vessels in the superficial dermis and hyperkeratosis of extremities. It is mostly seen in generalized form affecting the extremity of the body, but we report this case of solitary angiokeratoma of the tongue which is a very rare type.

Biocatalysis and Agricultural Biotechnology, 2017

Experimental trial of biomass yield, oil productivity and fatty acid profile of Chlorella lobopho... more Experimental trial of biomass yield, oil productivity and fatty acid profile of Chlorella lobophora in natural eutrophic wastewaters from three different sources was carried out using Bold's Basal Medium as the control. Eutrophication of water is a serious environment issue in agricultural as well as in many industrial zones in the world. But algal biomass production remains the most cost-effective and sustainable means to deal with eutrophic wastewater. Algal culture is the potential method of combining wastewater treatment, nutrient removal, resource recovery and simultaneous yield of biomass and bio-oils. Algal biomass has nutraceutical and biofuel applications. The major objective of the present experimentation was to test the suitability of different eutrophic wastewaters towards understanding the optimum requirements of microalgae for best biomass and oil yield. Influence of variations in nutrient composition of the wastewaters on chemical profile of the oil are also analyzed. Different water quality parameters were found significantly correlated to biomass characteristics of the alga. Oil productivity as well as chemical profile of the oil also exhibited interrelationships to water quality parameters. The oil of algal biomass taken from all kinds of wastewater sources is found suitable for biodiesel through transesterification. Overall, the method stands as model for preliminary screening of algae for economic utilization of wastewaters towards attaining high biomass yield with desired oil quality, especially for biodiesel production.

Scientific Reports, 2016

Treatment outcome after surgical removal in oral carcinoma is poor due to inadequate methodologie... more Treatment outcome after surgical removal in oral carcinoma is poor due to inadequate methodologies available for marking surgical margins. Even though some methodologies for intraoperative margin assessment are under clinical and preclinical trials for other solid tumours, a promising modality for oral cancer surgery is not developed. Fluorescent-based optical imaging using Near Infrared (NIR) dyes tagged to tumour specific target will be an optimal tool for this purpose. One such target, Gastrin Releasing Peptide Receptor (GRPR) was selected for the study, and its binding peptide, TM1-IR680, was tested for its efficacy for surgical margin prediction in murine orthotopic model of oral cancer, derived from primary samples. Here, for the first time in a preclinical analysis, we show that the size and margin of oral cancer can be predicted, as revealed by 3D-imaging. Interestingly, the peptide was sensitive enough to detect lymph nodes that harboured dispersed tumour cells before colon...

Indian Journal of Applied Research, Nov 1, 2014

International Conference on Nanoscience, Engineering and Technology (ICONSET 2011), 2011

Thin films of tin sulphides (SnxSy) were deposited on glass substrates by spray pyrolysis techniq... more Thin films of tin sulphides (SnxSy) were deposited on glass substrates by spray pyrolysis technique using precursor solutions of SnCl2.2H2O and thiourea and InCl3 at different substrate temperatures that vary in the range of 275 – 375°C. The physical properties of these films were characterized by using X-ray diffraction, Field Emission Scanning Electron Microscope, UV-Visible Spectrophotometer and Photoluminescence. The XRD

Peptides 2015, Proceedings of the 24th American Peptide Symposium, 2015

World Environmental and Water Resources Congress 2009, 2009

Water-sharing in a river basin by different users as well as between different stakeholders along... more Water-sharing in a river basin by different users as well as between different stakeholders along the river basin has been a serious problem and becomes more complex when there is an acute shortage of supply in the river basin. Many negotiations and interactions take place ...

Chemical Science, 2021

Synthetic alpha-helix based pores for selective sensing of peptides have not been characterized p... more Synthetic alpha-helix based pores for selective sensing of peptides have not been characterized previously.

Health Information Science, 2021

With the development of database systems and networking technologies, Hospital Information Manage... more With the development of database systems and networking technologies, Hospital Information Management Systems (HIMS) and web-based clinical or medical systems (such as the Medical Director, a generic GP clinical system) are widely used in health and clinical practices. Healthcare and medical service are more dataintensive and evidence-based since electronic health records are now used to track individuals' and communities' health information. These highlights substantially motivate and advance the emergence and the progress of health informatics research and practice. Health Informatics continues to gain interest from both academia and health industries. The significant initiatives of using information, knowledge and communication technologies in health industries ensures patient safety, improve population health and facilitate the delivery of government healthcare services. Books in the series will reflect technology's cross-disciplinary research in IT and health/medical science to assist in disease diagnoses, treatment, prediction and monitoring through the modeling, design, development, visualization, integration and management of health related information. These technologies include information systems, web technologies, data mining, image processing, user interaction and interfaces, sensors and wireless networking, and are applicable to a wide range of health-related information such as medical data, biomedical data, bioinformatics data, and public health data.

The use of organic fertilizer and insecticides forms the backbone & basic necessity of a poor far... more The use of organic fertilizer and insecticides forms the backbone & basic necessity of a poor farmer. The traditional methods of using chemical fertilizers and insecticides are not sufficient & satisfactory for increasing productivity of crop and to maintain the fertility of soil. Farmers use chemical fertilizers for growth of their crops. But there are many disadvantages to the crops if chemical fertilizers are applied to the soil. To reduce the efforts of farmer in preparing the organic mixture, by designing a low budget organic fertilizer and insecticides making machine. Whereas the chemical fertilizers are more costly in market, so it becomes difficult for poor farmers to purchase it. Organic fertilizer and insecticides manufacturing machine solves these both problems.

International Research Journal of Multidisciplinary Studies, 2016

Water scarcity is one of the major problem facing major cities of the world. Major problems regar... more Water scarcity is one of the major problem facing major cities of the world. Major problems regarding that are when either sump or bore well motor is started people forget to switch OFF these motors so water goes waste as well as electricity gets consumed. There is not fix schedule to start and stop motors so there is always problem of unwanted vacancy of water in overhead tank, people are facing such problems at midnight & situation becomes critical. Sumps as well as bore well motor can dry run giving electricity wastage. So overall wastage has been identified as a major culprit; this is one of the motivations for this research, to deploy computing techniques in creating a barrier to wastage in order to not only provide more financial gains and energy saving, but also help the environment and water cycle which in turn ensures that water is saved for our future. This paper presents research in embedding a control system into an automatic water pump controller through the use of diff...

International Research Journal of Multidisciplinary Technovation, 2020

An orphanage is a residential institution devoted to the care of orphan-children whose parents ar... more An orphanage is a residential institution devoted to the care of orphan-children whose parents are unwilling or unable to take care of them. The problem of orphan is acute due to urbanization and industrialization. Need for each of the orphanages varies in different categories such as food, money, clothes, medicine. Most of the people would like to help the orphanages but the major problem is that they have any idea on how to approach these orphanages. The main objective of this application is to develop a centralized site for orphanages. In our proposed system we try to create an interface between Orphanages\Old age Homes which are in need of charity and people/Volunteers who are willing to help these people. Volunteers can also approach the Orphanage managers regarding the help that they can afford. People can donate through Internet Banking or Online Money Payment applications.

Materials Today: Proceedings, 2021

Abstract Carbon nanotubes (CNT) are an outstanding development in the field of nanostructure. Uni... more Abstract Carbon nanotubes (CNT) are an outstanding development in the field of nanostructure. Unique characteristics of Carbon Nanotubes (CNT) make them a suitable reinforcing agent in Aluminium Metal Matrix composites. These composites are being anticipated in aviation for their high explicit quality just as utilitarian materials for their energizing mechanical and warm attributes. The property of carbon nanotube strengthened aluminum network (Al-CNT) composites mainly depends on the percentage weight of reinforced material in the base material. Thus the main objective of this review paper to addresses the concentration of CNT on tensile strength, yield strength and compressive strength of CNT - Al matrix composites.

Materials Today: Proceedings, 2021

Abstract In this study, AA5083 plates were friction stir processed to improve the hardness by ref... more Abstract In this study, AA5083 plates were friction stir processed to improve the hardness by refining the grains and dispersing the β phase in the matrix. Tool rotation speed, tool traverse speed, and tool shoulder diameter were varied as per the face-centered central composite design and FSP trials were performed. The wear resistance of the friction stir processed specimens was estimated by conducting a wear test using a pin-on-disc tribometer. It was observed that the wear resistance was higher than the base specimens and TRS, TTS and SD had a significant effect on the wear resistance. An artificial neural network model and a fuzzy logic model were developed to predict the wear resistance of the friction stir processed specimens. As the Sugeno Fuzzy model had greater prediction efficiency than the ANN model, it was used to study the effect of FSP process parameters on the wear resistance of the specimens. The results indicate that a TRS of 1000 rpm, TTS of 30 mm/min, and SD of 18 mm maximized the wear resistance of the processed plate to 8820 N-m/kg.

Research Journal of Engineering and Technology, 2019

ECS Journal of Solid State Science and Technology, 2016

1ST INTERNATIONAL CONFERENCE ON MANUFACTURING, MATERIAL SCIENCE AND ENGINEERING (ICMMSE-2019), 2019

Steering is the group of parts with joints which allows any vehicle to follow the required path. ... more Steering is the group of parts with joints which allows any vehicle to follow the required path. The traditional steering mechanism is to turn the front wheels using steering wheel with the help of steering columns and universal joints, to allow it to turn away to some extent from a straight line. The steering system must give a mechanical dominance over front wheel steering knuckles, contributing driver an effortless turning of front wheels in desired direction. The steering system is designed to withstand the stress of safely maneuvering the vehicle through any type of driving condition by continuously adjust the steered path of the vehicle. The steering system is to provides directional control of the vehicle with minimum input. In our project, the Ackermann steering system is designed for a go-kart. After designing the steering system, the Later simulation model of design is constructed for ensuring performance optimization, safety engineering for real-time conditions. A simulation is an operation of a real-world process done using workstation. By using simulation, a model can be embedded with multiple variations. These are capable of performing analysis and understanding of how single or multiple elements react to the simulated environment. The platform selected for the simulation process is SOLID WORKS software.The final stage of this project is structural fabrication of the steering system based on our design and complete analysis. The material appropriate for creation of this system is mild steel, its price is low while it facilitates material properties that are sustainable for many applications. Main point is its strength to weight ratio which is very advantage when compared to all steels. The objective of present work is to provide a robust steering system, with high performance for a Go-Kart vehicle.

Materials Chemistry and Physics, 2019

In this work, we have synthesized a series of nanocomposites of few layered defective graphene ox... more In this work, we have synthesized a series of nanocomposites of few layered defective graphene oxide (GO) and mesoporous SiO 2 , and studied their frequency (1-10MHz) and temperature (50-400 o C) dependent dielectric properties. We have tuned the surface area and pore size of mesoporous SiO 2 and conjugated the mover the GO sheets to achieve new hybrid nanocomposites. The formation of conjugation has been confirmed through microscopy and spectroscopy studies. Impedance spectroscopy indicated a very high dielectric constant for the novel composites that was found to being the range of 7.961 x 10 5 to 2.191 x 10 3 and 2.790 x 10 8 to 2.770 x 10 4 at the frequencies of 1Hz and 10 kHz at 50 o C and 400 o C, respectively. Such increase in the dielectric constants is attributed to the formation of chemical conjugation on the GO with mesoporous SiO 2 which results due to change in the orientation and space charge polarization as well as the porous behavior of the composites studied at different conditions. Temperature and frequency dependent dc and ac conductivities have also been calculated through the impedance analysis. They were found to be c.a. 0.000 to 0.25 x 10-3 S/m and 0.007 to 0.120 S/m, respectively, irrespective of the frequency and temperature for the best composite. We show a very simple and cost effective synthesis in the present study. Further, we engineered new novel new nano composites those display high dielectric constant, by utilizing this approach. Thus, this simple approach can be exploited to tune the desired properties of nanocomposites those can be used in various electronic devices.

Indian journal of dental research : official publication of Indian Society for Dental Research

Angiokeratoma is a benign cutaneous lesion of capillaries. It is characterized by large dilated b... more Angiokeratoma is a benign cutaneous lesion of capillaries. It is characterized by large dilated blood vessels in the superficial dermis and hyperkeratosis of extremities. It is mostly seen in generalized form affecting the extremity of the body, but we report this case of solitary angiokeratoma of the tongue which is a very rare type.

Biocatalysis and Agricultural Biotechnology, 2017

Experimental trial of biomass yield, oil productivity and fatty acid profile of Chlorella lobopho... more Experimental trial of biomass yield, oil productivity and fatty acid profile of Chlorella lobophora in natural eutrophic wastewaters from three different sources was carried out using Bold's Basal Medium as the control. Eutrophication of water is a serious environment issue in agricultural as well as in many industrial zones in the world. But algal biomass production remains the most cost-effective and sustainable means to deal with eutrophic wastewater. Algal culture is the potential method of combining wastewater treatment, nutrient removal, resource recovery and simultaneous yield of biomass and bio-oils. Algal biomass has nutraceutical and biofuel applications. The major objective of the present experimentation was to test the suitability of different eutrophic wastewaters towards understanding the optimum requirements of microalgae for best biomass and oil yield. Influence of variations in nutrient composition of the wastewaters on chemical profile of the oil are also analyzed. Different water quality parameters were found significantly correlated to biomass characteristics of the alga. Oil productivity as well as chemical profile of the oil also exhibited interrelationships to water quality parameters. The oil of algal biomass taken from all kinds of wastewater sources is found suitable for biodiesel through transesterification. Overall, the method stands as model for preliminary screening of algae for economic utilization of wastewaters towards attaining high biomass yield with desired oil quality, especially for biodiesel production.

Scientific Reports, 2016

Treatment outcome after surgical removal in oral carcinoma is poor due to inadequate methodologie... more Treatment outcome after surgical removal in oral carcinoma is poor due to inadequate methodologies available for marking surgical margins. Even though some methodologies for intraoperative margin assessment are under clinical and preclinical trials for other solid tumours, a promising modality for oral cancer surgery is not developed. Fluorescent-based optical imaging using Near Infrared (NIR) dyes tagged to tumour specific target will be an optimal tool for this purpose. One such target, Gastrin Releasing Peptide Receptor (GRPR) was selected for the study, and its binding peptide, TM1-IR680, was tested for its efficacy for surgical margin prediction in murine orthotopic model of oral cancer, derived from primary samples. Here, for the first time in a preclinical analysis, we show that the size and margin of oral cancer can be predicted, as revealed by 3D-imaging. Interestingly, the peptide was sensitive enough to detect lymph nodes that harboured dispersed tumour cells before colon...

Indian Journal of Applied Research, Nov 1, 2014

International Conference on Nanoscience, Engineering and Technology (ICONSET 2011), 2011

Thin films of tin sulphides (SnxSy) were deposited on glass substrates by spray pyrolysis techniq... more Thin films of tin sulphides (SnxSy) were deposited on glass substrates by spray pyrolysis technique using precursor solutions of SnCl2.2H2O and thiourea and InCl3 at different substrate temperatures that vary in the range of 275 – 375°C. The physical properties of these films were characterized by using X-ray diffraction, Field Emission Scanning Electron Microscope, UV-Visible Spectrophotometer and Photoluminescence. The XRD

Peptides 2015, Proceedings of the 24th American Peptide Symposium, 2015

World Environmental and Water Resources Congress 2009, 2009

Water-sharing in a river basin by different users as well as between different stakeholders along... more Water-sharing in a river basin by different users as well as between different stakeholders along the river basin has been a serious problem and becomes more complex when there is an acute shortage of supply in the river basin. Many negotiations and interactions take place ...