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Papers by K. Tiisma

Research paper thumbnail of Stochastic Control of Growth in Fed-Batch Culture of Bacteria

Proceedings of the Academy of Sciences of the Estonian SSR. Physics. Mathematics, 1988

STOCHASTIC CONTROL OF GROWTH IN FED-BATCH CULTURE OF BACTERIA (Presented by E. Lippmaa) Using the... more STOCHASTIC CONTROL OF GROWTH IN FED-BATCH CULTURE OF BACTERIA (Presented by E. Lippmaa) Using the stoichiometric equation of growth and Monod type kinetic equation, a deterministic model of growth of microorganisms in fed-batch culture was built. A stochastic model of the process was developed on the basis of the deterministic description. A stochastic control algorithm which is using filtered data was developed.

Research paper thumbnail of Glucose‐Limited fed‐batch cultivation of Escherichia coli with computer‐controlled fixed growth rate

Biotechnology and Bioengineering, 1990

Research paper thumbnail of Glucose-Limited fed-batch cultivation ofEscherichia coli with computer-controlled fixed growth rate

Biotechnology and Bioengineering, 1990

Growth cessation of Escherichia coli in nondialysis fedbatch culture at biomass densities over 30... more Growth cessation of Escherichia coli in nondialysis fedbatch culture at biomass densities over 30-40 g/L has been shown to be the result of the accumulation of acetate, lactate, pyruvate, succinate, propionate, and isobutyrate in the culture broth.' This conclusion was supported by the fact that high cell concentrations (140 g/L) and cellular yields were achieved in dialysis fed-batch culture of E. coli.

Research paper thumbnail of Stochastic Control of Growth in Fed-Batch Culture of Bacteria

Proceedings of the Academy of Sciences of the Estonian SSR. Physics. Mathematics, 1988

STOCHASTIC CONTROL OF GROWTH IN FED-BATCH CULTURE OF BACTERIA (Presented by E. Lippmaa) Using the... more STOCHASTIC CONTROL OF GROWTH IN FED-BATCH CULTURE OF BACTERIA (Presented by E. Lippmaa) Using the stoichiometric equation of growth and Monod type kinetic equation, a deterministic model of growth of microorganisms in fed-batch culture was built. A stochastic model of the process was developed on the basis of the deterministic description. A stochastic control algorithm which is using filtered data was developed.

Research paper thumbnail of Glucose‐Limited fed‐batch cultivation of Escherichia coli with computer‐controlled fixed growth rate

Biotechnology and Bioengineering, 1990

Research paper thumbnail of Glucose-Limited fed-batch cultivation ofEscherichia coli with computer-controlled fixed growth rate

Biotechnology and Bioengineering, 1990

Growth cessation of Escherichia coli in nondialysis fedbatch culture at biomass densities over 30... more Growth cessation of Escherichia coli in nondialysis fedbatch culture at biomass densities over 30-40 g/L has been shown to be the result of the accumulation of acetate, lactate, pyruvate, succinate, propionate, and isobutyrate in the culture broth.' This conclusion was supported by the fact that high cell concentrations (140 g/L) and cellular yields were achieved in dialysis fed-batch culture of E. coli.

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