Kamini Gupta - Academia.edu (original) (raw)
Papers by Kamini Gupta
Introduction: The aim of this paper was to evaluate the thoracic manifestations associated with t... more Introduction: The aim of this paper was to evaluate the thoracic manifestations associated with the Connective tissue disorders, with an emphasis on interstitial and airway disease pattern on the High Resolution computed tomography (HRCT) findings. Material and methods: The present study was conducted for a period of one year. A total of 70 patients with various connective tissue disorders having respiratory complaints were evaluated. Results: During the study period 70 patients (58 females and 12 males) underwent evaluation. Cough and dyspnea were the most common presenting symptoms. Variety of thoracic abnormalities were in detected in 67 (95%) cases. Most common abnormality detected on HRCT was interstitial fibrosis/interstitial lung disease present in 42(60%) cases. Most common parenchymal abnormalities seen were reticulations (61.4%), ground glass opacification (40%), mosaic attenuation (32.8%) and honeycombing (24.3%). Airway abnormalities seen were bronchiectasis (48.5%), emp...
Oman Medical Journal, 2015
assive hemoptysis is the most serious medical emergency and warrants swift and comprehensive eval... more assive hemoptysis is the most serious medical emergency and warrants swift and comprehensive evaluation of the lung parenchyma, airways, and thoracic vasculature. Anomalies of thoracic vasculature constitute an important and uncommon category as causes of hemoptysis. Multidetector computed tomography (MDCT) is the optimal imaging modality for evaluating hemoptysis. In addition to showing the lung parenchyma and airways, it allows the evaluation of the integrity of pulmonary, bronchial, and non-bronchial systemic arteries within the chest. 1,2 Various congenital and acquired anomalies affect the pulmonary vasculature. Awareness of the radiologic manifestations of the disease entities and potential complications secondary to infection, vasculitis, or collateralization may aid early diagnosis. We report the cases of three patients who presented with hemoptysis. The right pulmonary artery was affected in all three, either due to a congenital or acquired cause, and led to systemic collateralization, which resulted in hemoptysis.
Surgical neurology international, Jan 20, 2010
Tuberculosis is endemic in many counteries like India. It can infect any site in the central nerv... more Tuberculosis is endemic in many counteries like India. It can infect any site in the central nervous system. However, islolated involvement of the sellar and suprasellar region is rare. Sellar tuberculoma with hemorrhage is even more rare. We present magnetic resonance (MR) findings in case of sellar and suprasellar tuberculoma with hemorrhage. A 40-year-old female patient presented with a 1-month history of persistent headache and blurred vision on the left side. A contrast-enhanced MR study revealed peripherally enhancing sellar and suprasellar mass with hemorrhage with compression of the left half of the optic chiasma. There was also evidence of infundibular thickening and enhancement of the adjacent dura. The mass was approached through a transphenoidal approach and was partially resected. Subsequent histopathology was suggestive of tuberculosis. The patient was put on anti-tubercular therapy. Patient reported significant improvement in symptoms. Follow-up MR done 8 months later...
Journal of clinical and diagnostic research : JCDR, 2014
Spinal trauma is relatively more common in young active individuals. Although its mortality is lo... more Spinal trauma is relatively more common in young active individuals. Although its mortality is low, it is an important cause of long term disability. Magnetic resonance imaging (MRI) can accurately depict presence and extent of spinal cord injury (SCI) in these patients. This study was aimed to look for various qualitative and quantitative MRI findings which are predictive of initial neurological deficit in patients with spinal trauma and final outcome on follow-up. The present study was conducted on 50 patients with suspected acute cervical or dorsal spinal trauma presenting for MRI study. American Spinal Injury Association (ASIA) motor score was used for assessing neurological status at the time of presentation, at the time of discharge/2weeks and at 3-6 months follow up. Various MRI qualitative and quantitative parameters were evaluated for correlation with severity of spinal injury. Normal baseline MRI (pattern 0) was seen in 12 subjects and was associated with incomplete SCI in...
Pan African Medical Journal, 2015
Tuberous sclerosis complex (TSC) manifests predominantly as a neurocutaneous disorder. Lymphangio... more Tuberous sclerosis complex (TSC) manifests predominantly as a neurocutaneous disorder. Lymphangioleiomyomatosis (LAM) is a rare pulmonary manifestation of TSC. Imaging evaluation plays an important role in the assessment of patients with tuberous sclerosis complex. In newly diagnosed patients, it helps not only to confirm the diagnosis of TSC, but also helps in identifying clinically significant complications.We describe the radiological findings in lungs and other organs in a middle aged female with TSC.
Pan African Medical Journal, 2014
Splenosis is a benign condition among patients with a history of splenic trauma or surgery. Most ... more Splenosis is a benign condition among patients with a history of splenic trauma or surgery. Most cases of splenosis are intra abdominal due to direct seeding of surrounding structures, although these heterotopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. The increased prevalence of abdominal trauma due to road accidents and the growing armamentarium of available imaging modalities suggest that abdominal splenosis may be expected more often than ever. We, in this article emphasize the crucial role of taking a thorough patient's medical history concerning splenic trauma in the past and the use of novel non invasive diagnostics modalities that allow accurate diagnosis.
Annals of African Medicine, 2014
Journal of Pulmonary & Respiratory Medicine, 2012
International Journal of Anatomy Radiology and Surgery, 2018
Introduction: MRI plays a significant role in diagnosing viral encephalitis. It aids the diagnosi... more Introduction: MRI plays a significant role in diagnosing viral encephalitis. It aids the diagnosis of causative agent, conditions mimicking the disease, identification of complications and hence prognostication of the patient. The present study analysed the MRI spectrum of different types of viral encephalitis and its role in diagnosing the causative virus. Aim: To study MRI findings of viral encephalitis and their correlation with CSF/biochemical/histopathological microbiological analysis. Materials and Methods: All patients suspected or previously diagnosed of CNS infections and referred to the department of Radiodiagnosis at Dayanand medical college and hospital, Ludhiana for imaging over a period of one and a half years were included in this study. Results: Most of the patients presented with fever and altered sensorium. CSF showed mildly raised proteins and pleocytosis. Asymmetric involvement of medial temporal lobes, cingulated gyri and insular cortices in herpes simplex infec...
Indian Journal of Case Reports, 2020
Endometriosis is a common gynecologic disorder that presents with chronic pelvic pain or infertil... more Endometriosis is a common gynecologic disorder that presents with chronic pelvic pain or infertility. It is the presence of endometrial tissue outside the uterus. It is typically present in the pelvis, such as on the ovaries and pelvic peritoneum. It may also involve the bowel, ureter or bladder, and the neurovascular bundle in the leg. We, hereby, report that the case of a lady who presented to us with catamenial leg pain on her right side was diagnosed to have lumbosacral plexopathy with underlying etiology as endometriosis on evaluation, an unusual presentation of a disease.
Journal of Radiation and Cancer Research, 2016
Second malignant neoplasm is a rare but dreaded late sequelae of the treated primary childhood ma... more Second malignant neoplasm is a rare but dreaded late sequelae of the treated primary childhood malignancies. Surgical excision combined with radiochemotherapy represents the gold standard of therapy for medulloblastoma. The effectiveness of such a combined treatment has encouraged the use of radiotherapy even in young pediatric patients, in spite of the increased risk of a second radio-induced malignancy. Irradiation is the well-known risk factor for the development of benign and malignant thyroid tumors. Children are more exposed to this risk because their thyroid gland is more sensitive to the carcinogenic effect of ionizing radiation. We report the case of a 20-year-old male who initially presented at the age of 2 years with a medulloblastoma and was treated with surgery and radiotherapy. The patient again presented 18 years after radiotherapy with bilateral neck masses which proved to be lymphadenopathy secondary to papillary carcinoma of the thyroid. The patient also had multiple bilateral metastatic pulmonary nodules. Radio-induced thyroid tumors are well-recognized nosographic entities due to the particular sensitivity of this gland to ionizing radiations. However, only a few papers on radio-induced thyroid neoplasms after the central nervous system (CNS) irradiation have been published in the literature. We report an additional case of thyroid neoplasm following childhood CNS irradiation for the treatment of posterior fossa medulloblastoma and emphasize that clinicians should judiciously use the radiotherapy for treatment of childhood malignancies and also radiologists should be familiar with the long-term complications of antineoplastic therapies to facilitate early diagnosis and treatment.
The Indian journal of radiology and imaging
Leiomyosarcoma of primary vascular origin is a rare tumor, which arises mainly from the inferior ... more Leiomyosarcoma of primary vascular origin is a rare tumor, which arises mainly from the inferior vena cava (IVC). The middle part of IVC is most often affected. There is a strong predilection for women. Clinical symptoms depend upon the size and location of tumor.
Muller Journal of Medical Sciences and Research, 2013
The diagnosis of yo-yo reflux in patients with partial collecting system duplications is difficul... more The diagnosis of yo-yo reflux in patients with partial collecting system duplications is difficult. We report a case of recurrent urinary tract infections due to partial duplication of the collecting system in which yo-yo reflux is demonstrated with color and pulse wave Doppler. Our aim is to highlight the fact that radiologists and clinicians should be aware of this noninvasive, inexpensive, and easily accessible modality so as to diagnose this phenomenon more frequently in future.
Journal of Orthopaedics and Allied Sciences, 2013
Objective: The purpose of this study was to correlate clinical, MRI, and arthroscopic findings in... more Objective: The purpose of this study was to correlate clinical, MRI, and arthroscopic findings in diagnosing ligament and meniscus tears in knee joint injuries. Materials and Methods: Our study included 20 patients in the age range of 11-60 years who were referred to radiology department for MRI of knee joint following injury to the knee. Prior to MRI, a detailed history, clinical, and local examination was done in all the subjects. MRI was carried out on 1.5 Tesla MR Machine and the standard protocol consisted of fat-suppressed PD (TE 45, TR 2800) in axial, sagittal, and coronal planes, T2W (TE 80, TR 4000) in sagittal plane and T1W (TE 11, TR 495) in sagittal plane. All the patients underwent arthroscopy by an orthopedic surgeon. Results: MR had 100% sensitivity and NPV of diagnosing ACL tears in this study. Clinical examination had sensitivity of 88% and NPV 75% in diagnosing ACL injuries. There was high NPV of MR examination (96%) in diagnosing meniscus tear while the PPV of MR examination was low (71%). These values were low in case of clinical examination. Conclusions: MRI is a useful non-invasive modality having high diagnostic accuracy, sensitivity, and negative predictive value making it a very reliable screening test for diagnosing internal derangements.
Journal of Mahatma Gandhi Institute of Medical Sciences, 2013
Journal of Child Neurology, 2011
Magnetic resonance imaging findings in Reye syndrome have been reported only infrequently. A prev... more Magnetic resonance imaging findings in Reye syndrome have been reported only infrequently. A previously well 8-year-old boy presented with repeated episodes of vomiting and abdominal pain followed by altered sensorium and tonic spasms. This occurred 5 days after upper respiratory tract infection. His laboratory data revealed elevated liver enzymes, prolonged prothrombin time, and high blood ammonia levels. Magnetic resonance imaging of the brain done on the day of admission revealed diffuse cerebral edema and signal alterations in brainstem, bilateral thalami, medial temporal lobes, parasagittal cortex, and cerebellar and subcortical white matter. Diffusion restriction was seen in thalami, midbrain, cerebellar white matter, subcortical white matter, and parasaggital cortex in the watershed territory. The patient made a full recovery. Follow-up magnetic resonance imaging after a week revealed complete resolution of all except thalamic lesions. Although diffusion restriction in thalam...
Indian Journal of Radiology and Imaging, 2010
Acute calcific discitis is a rare but well-known condition of unknown etiology. In symptomatic ca... more Acute calcific discitis is a rare but well-known condition of unknown etiology. In symptomatic cases, the most common site is the cervical spine. We describe the CT scan and MRI findings in a symptomatic patient, with a lesion in the dorsolumbar spine.
Indian Journal of Surgical Oncology, 2011
Introduction: The aim of this paper was to evaluate the thoracic manifestations associated with t... more Introduction: The aim of this paper was to evaluate the thoracic manifestations associated with the Connective tissue disorders, with an emphasis on interstitial and airway disease pattern on the High Resolution computed tomography (HRCT) findings. Material and methods: The present study was conducted for a period of one year. A total of 70 patients with various connective tissue disorders having respiratory complaints were evaluated. Results: During the study period 70 patients (58 females and 12 males) underwent evaluation. Cough and dyspnea were the most common presenting symptoms. Variety of thoracic abnormalities were in detected in 67 (95%) cases. Most common abnormality detected on HRCT was interstitial fibrosis/interstitial lung disease present in 42(60%) cases. Most common parenchymal abnormalities seen were reticulations (61.4%), ground glass opacification (40%), mosaic attenuation (32.8%) and honeycombing (24.3%). Airway abnormalities seen were bronchiectasis (48.5%), emp...
Oman Medical Journal, 2015
assive hemoptysis is the most serious medical emergency and warrants swift and comprehensive eval... more assive hemoptysis is the most serious medical emergency and warrants swift and comprehensive evaluation of the lung parenchyma, airways, and thoracic vasculature. Anomalies of thoracic vasculature constitute an important and uncommon category as causes of hemoptysis. Multidetector computed tomography (MDCT) is the optimal imaging modality for evaluating hemoptysis. In addition to showing the lung parenchyma and airways, it allows the evaluation of the integrity of pulmonary, bronchial, and non-bronchial systemic arteries within the chest. 1,2 Various congenital and acquired anomalies affect the pulmonary vasculature. Awareness of the radiologic manifestations of the disease entities and potential complications secondary to infection, vasculitis, or collateralization may aid early diagnosis. We report the cases of three patients who presented with hemoptysis. The right pulmonary artery was affected in all three, either due to a congenital or acquired cause, and led to systemic collateralization, which resulted in hemoptysis.
Surgical neurology international, Jan 20, 2010
Tuberculosis is endemic in many counteries like India. It can infect any site in the central nerv... more Tuberculosis is endemic in many counteries like India. It can infect any site in the central nervous system. However, islolated involvement of the sellar and suprasellar region is rare. Sellar tuberculoma with hemorrhage is even more rare. We present magnetic resonance (MR) findings in case of sellar and suprasellar tuberculoma with hemorrhage. A 40-year-old female patient presented with a 1-month history of persistent headache and blurred vision on the left side. A contrast-enhanced MR study revealed peripherally enhancing sellar and suprasellar mass with hemorrhage with compression of the left half of the optic chiasma. There was also evidence of infundibular thickening and enhancement of the adjacent dura. The mass was approached through a transphenoidal approach and was partially resected. Subsequent histopathology was suggestive of tuberculosis. The patient was put on anti-tubercular therapy. Patient reported significant improvement in symptoms. Follow-up MR done 8 months later...
Journal of clinical and diagnostic research : JCDR, 2014
Spinal trauma is relatively more common in young active individuals. Although its mortality is lo... more Spinal trauma is relatively more common in young active individuals. Although its mortality is low, it is an important cause of long term disability. Magnetic resonance imaging (MRI) can accurately depict presence and extent of spinal cord injury (SCI) in these patients. This study was aimed to look for various qualitative and quantitative MRI findings which are predictive of initial neurological deficit in patients with spinal trauma and final outcome on follow-up. The present study was conducted on 50 patients with suspected acute cervical or dorsal spinal trauma presenting for MRI study. American Spinal Injury Association (ASIA) motor score was used for assessing neurological status at the time of presentation, at the time of discharge/2weeks and at 3-6 months follow up. Various MRI qualitative and quantitative parameters were evaluated for correlation with severity of spinal injury. Normal baseline MRI (pattern 0) was seen in 12 subjects and was associated with incomplete SCI in...
Pan African Medical Journal, 2015
Tuberous sclerosis complex (TSC) manifests predominantly as a neurocutaneous disorder. Lymphangio... more Tuberous sclerosis complex (TSC) manifests predominantly as a neurocutaneous disorder. Lymphangioleiomyomatosis (LAM) is a rare pulmonary manifestation of TSC. Imaging evaluation plays an important role in the assessment of patients with tuberous sclerosis complex. In newly diagnosed patients, it helps not only to confirm the diagnosis of TSC, but also helps in identifying clinically significant complications.We describe the radiological findings in lungs and other organs in a middle aged female with TSC.
Pan African Medical Journal, 2014
Splenosis is a benign condition among patients with a history of splenic trauma or surgery. Most ... more Splenosis is a benign condition among patients with a history of splenic trauma or surgery. Most cases of splenosis are intra abdominal due to direct seeding of surrounding structures, although these heterotopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. The increased prevalence of abdominal trauma due to road accidents and the growing armamentarium of available imaging modalities suggest that abdominal splenosis may be expected more often than ever. We, in this article emphasize the crucial role of taking a thorough patient's medical history concerning splenic trauma in the past and the use of novel non invasive diagnostics modalities that allow accurate diagnosis.
Annals of African Medicine, 2014
Journal of Pulmonary & Respiratory Medicine, 2012
International Journal of Anatomy Radiology and Surgery, 2018
Introduction: MRI plays a significant role in diagnosing viral encephalitis. It aids the diagnosi... more Introduction: MRI plays a significant role in diagnosing viral encephalitis. It aids the diagnosis of causative agent, conditions mimicking the disease, identification of complications and hence prognostication of the patient. The present study analysed the MRI spectrum of different types of viral encephalitis and its role in diagnosing the causative virus. Aim: To study MRI findings of viral encephalitis and their correlation with CSF/biochemical/histopathological microbiological analysis. Materials and Methods: All patients suspected or previously diagnosed of CNS infections and referred to the department of Radiodiagnosis at Dayanand medical college and hospital, Ludhiana for imaging over a period of one and a half years were included in this study. Results: Most of the patients presented with fever and altered sensorium. CSF showed mildly raised proteins and pleocytosis. Asymmetric involvement of medial temporal lobes, cingulated gyri and insular cortices in herpes simplex infec...
Indian Journal of Case Reports, 2020
Endometriosis is a common gynecologic disorder that presents with chronic pelvic pain or infertil... more Endometriosis is a common gynecologic disorder that presents with chronic pelvic pain or infertility. It is the presence of endometrial tissue outside the uterus. It is typically present in the pelvis, such as on the ovaries and pelvic peritoneum. It may also involve the bowel, ureter or bladder, and the neurovascular bundle in the leg. We, hereby, report that the case of a lady who presented to us with catamenial leg pain on her right side was diagnosed to have lumbosacral plexopathy with underlying etiology as endometriosis on evaluation, an unusual presentation of a disease.
Journal of Radiation and Cancer Research, 2016
Second malignant neoplasm is a rare but dreaded late sequelae of the treated primary childhood ma... more Second malignant neoplasm is a rare but dreaded late sequelae of the treated primary childhood malignancies. Surgical excision combined with radiochemotherapy represents the gold standard of therapy for medulloblastoma. The effectiveness of such a combined treatment has encouraged the use of radiotherapy even in young pediatric patients, in spite of the increased risk of a second radio-induced malignancy. Irradiation is the well-known risk factor for the development of benign and malignant thyroid tumors. Children are more exposed to this risk because their thyroid gland is more sensitive to the carcinogenic effect of ionizing radiation. We report the case of a 20-year-old male who initially presented at the age of 2 years with a medulloblastoma and was treated with surgery and radiotherapy. The patient again presented 18 years after radiotherapy with bilateral neck masses which proved to be lymphadenopathy secondary to papillary carcinoma of the thyroid. The patient also had multiple bilateral metastatic pulmonary nodules. Radio-induced thyroid tumors are well-recognized nosographic entities due to the particular sensitivity of this gland to ionizing radiations. However, only a few papers on radio-induced thyroid neoplasms after the central nervous system (CNS) irradiation have been published in the literature. We report an additional case of thyroid neoplasm following childhood CNS irradiation for the treatment of posterior fossa medulloblastoma and emphasize that clinicians should judiciously use the radiotherapy for treatment of childhood malignancies and also radiologists should be familiar with the long-term complications of antineoplastic therapies to facilitate early diagnosis and treatment.
The Indian journal of radiology and imaging
Leiomyosarcoma of primary vascular origin is a rare tumor, which arises mainly from the inferior ... more Leiomyosarcoma of primary vascular origin is a rare tumor, which arises mainly from the inferior vena cava (IVC). The middle part of IVC is most often affected. There is a strong predilection for women. Clinical symptoms depend upon the size and location of tumor.
Muller Journal of Medical Sciences and Research, 2013
The diagnosis of yo-yo reflux in patients with partial collecting system duplications is difficul... more The diagnosis of yo-yo reflux in patients with partial collecting system duplications is difficult. We report a case of recurrent urinary tract infections due to partial duplication of the collecting system in which yo-yo reflux is demonstrated with color and pulse wave Doppler. Our aim is to highlight the fact that radiologists and clinicians should be aware of this noninvasive, inexpensive, and easily accessible modality so as to diagnose this phenomenon more frequently in future.
Journal of Orthopaedics and Allied Sciences, 2013
Objective: The purpose of this study was to correlate clinical, MRI, and arthroscopic findings in... more Objective: The purpose of this study was to correlate clinical, MRI, and arthroscopic findings in diagnosing ligament and meniscus tears in knee joint injuries. Materials and Methods: Our study included 20 patients in the age range of 11-60 years who were referred to radiology department for MRI of knee joint following injury to the knee. Prior to MRI, a detailed history, clinical, and local examination was done in all the subjects. MRI was carried out on 1.5 Tesla MR Machine and the standard protocol consisted of fat-suppressed PD (TE 45, TR 2800) in axial, sagittal, and coronal planes, T2W (TE 80, TR 4000) in sagittal plane and T1W (TE 11, TR 495) in sagittal plane. All the patients underwent arthroscopy by an orthopedic surgeon. Results: MR had 100% sensitivity and NPV of diagnosing ACL tears in this study. Clinical examination had sensitivity of 88% and NPV 75% in diagnosing ACL injuries. There was high NPV of MR examination (96%) in diagnosing meniscus tear while the PPV of MR examination was low (71%). These values were low in case of clinical examination. Conclusions: MRI is a useful non-invasive modality having high diagnostic accuracy, sensitivity, and negative predictive value making it a very reliable screening test for diagnosing internal derangements.
Journal of Mahatma Gandhi Institute of Medical Sciences, 2013
Journal of Child Neurology, 2011
Magnetic resonance imaging findings in Reye syndrome have been reported only infrequently. A prev... more Magnetic resonance imaging findings in Reye syndrome have been reported only infrequently. A previously well 8-year-old boy presented with repeated episodes of vomiting and abdominal pain followed by altered sensorium and tonic spasms. This occurred 5 days after upper respiratory tract infection. His laboratory data revealed elevated liver enzymes, prolonged prothrombin time, and high blood ammonia levels. Magnetic resonance imaging of the brain done on the day of admission revealed diffuse cerebral edema and signal alterations in brainstem, bilateral thalami, medial temporal lobes, parasagittal cortex, and cerebellar and subcortical white matter. Diffusion restriction was seen in thalami, midbrain, cerebellar white matter, subcortical white matter, and parasaggital cortex in the watershed territory. The patient made a full recovery. Follow-up magnetic resonance imaging after a week revealed complete resolution of all except thalamic lesions. Although diffusion restriction in thalam...
Indian Journal of Radiology and Imaging, 2010
Acute calcific discitis is a rare but well-known condition of unknown etiology. In symptomatic ca... more Acute calcific discitis is a rare but well-known condition of unknown etiology. In symptomatic cases, the most common site is the cervical spine. We describe the CT scan and MRI findings in a symptomatic patient, with a lesion in the dorsolumbar spine.
Indian Journal of Surgical Oncology, 2011