Ayhan Karabulut - Academia.edu (original) (raw)
Papers by Ayhan Karabulut
DergiPark (Istanbul University), Dec 3, 2019
Mesane taşı oluşumunda birçok etiyolojik sebep yer alabilir. Mesane içerisinde yabancı cisim varl... more Mesane taşı oluşumunda birçok etiyolojik sebep yer alabilir. Mesane içerisinde yabancı cisim varlığı bu nedenlerden biridir. Bu yazıda, daha önce çıkartılamayan bir üretral foley kateterin, balonunun patlatılarak çıkartılması neticesinde mesanede kalan artık bir lateks fragman üzerinde meydana gelmiş mesane taşlı bir olguyu sunuyoruz.
The New Journal of Urology, Oct 1, 2017
Kist hidatik, ekinokokkus granulosus'a bağlı olarak oluşan ve hayvancılıkla uğraşan toplumlar... more Kist hidatik, ekinokokkus granulosus'a bağlı olarak oluşan ve hayvancılıkla uğraşan toplumlarda sık görülen, genellikle karaciğer ve akciğer yerleşimli kistik bir hastalıktır. Bu hastalık seyrek olarak diğer organlar ve vücut boşluklarında da görülebilir. Biz bu yazıda izole retroperitoneal kist hidatikli bir olguyu sunuyoruzHydatid cyst is a cystic disease usually associated with liver and lung, which is common in societies engaged in animal husbandry due to echinococcus granulosus. This disease is rarely seen in other organs and body cavities. In this article we present a case of isolated retroperitoneal hydatid cys
Archivos espanoles de urologia, 2019
Archivos españoles de urología, 2019
Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologi... more Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologies. In this article, we report a a post- cesarean vesicouteri fistula with review of the literature.
Squamous cell carcinoma of the urinary tract is a very rarely encountered tumor. It is more frequ... more Squamous cell carcinoma of the urinary tract is a very rarely encountered tumor. It is more frequently reported in bladder and male urethra than in renal pelvis. With the addition of new cases in the literature, the impact of its features, such as the location and the stage of the tumor, on the outcome will be highlighted. Here, we present a case with renal squamous cell carcinoma located in the upper caliceal system and discuss it in the light of current literature. (Turk J Cancer 2002;32(1):20-24)
OZ Mesane tasi olusumunda bircok etiyolojik sebep yer alabilir. Mesane icerisinde yabanci cisim v... more OZ Mesane tasi olusumunda bircok etiyolojik sebep yer alabilir. Mesane icerisinde yabanci cisim varligi bu nedenlerden biridir. Bu yazida, daha once cikartilamayan bir uretral foley kateterin, balonunun patlatilarak cikartilmasi neticesinde mesanede kalan artik bir lateks fragman uzerinde meydana gelmis mesane tasli bir olguyu sunuyoruz.
Urolithiasis, 2016
the stones closer than 2 cm to the UPJ was 23.1 % for the pneumatic group versus 64 % for the las... more the stones closer than 2 cm to the UPJ was 23.1 % for the pneumatic group versus 64 % for the laser group (p < 0.01). Lithotripsy time was significantly longer in group-2 (16.48 ± 4.74 min) than group-1 (12.24 ± 3.95 min) (p < 0.01). Ho:YAG laser lithotripsy is more successful than pneumatic lithotripsy for upper ureteral stones and a retropulsion prevention device does not equalize the surgical success of Ho:YAG laser and pneumatic lithotripters for upper ureteral stones on the first postoperative day and one month after surgery. Although the success rate of the first month after surgery is higher in group-2, the difference is not statistically significant.
Turkiye Klinikleri Journal of Urology, 2014
In geriatric female patients with urinary incontinence, pelvic organ prolapse (POP) can also be r... more In geriatric female patients with urinary incontinence, pelvic organ prolapse (POP) can also be recognized during physical examination. Sometimes obliterative surgery may prefered instead of reconstructive surgical techniques in patients with serious comorbidities. We are reporting a 74-years-old patient with hemiplegia and stage 4 pelvic organ proplapse (POP-Q) who underwent colpocleisis as the surgical treatment. LeFort Colpocleisis technique can be used for POP teratment in geriatric patient groups and has high success rates. In this article, benefits and complications of this technique is disscussed under the light of literature.
European Urology Supplements, 2011
Materials & Methods: EFS was performed on phenylephrine (PhE) pre-contracted penile corpus cavern... more Materials & Methods: EFS was performed on phenylephrine (PhE) pre-contracted penile corpus cavernosum smooth muscle from male New Zealand White rabbits. The intrinsic nerves were field-stimulated electrically (voltage, 30 V; pulse duration, 1 ms; trains of pulses, 10 seconds; train interval, 3-5 min; frequency, 0.5-32 Hz). We also investigated the penile tracing elicited by EFS (voltage, 30 V; pulse duration, 1 ms; frequency, 8 Hz) on guanethidine (Guan), tetrodotoxin (TTX), Nω nitro-L-arginine-methyl ester (L-NAME), atropine or eserine pre-incubated tissues. results: We obtained consilient results from both models. Phase I was abolished by L-NAME. Phase II was significantly decreased by eserine and Guan but increased by L-NAME. Phase III was abolished by atropine but enhanced by eserine and Guan. TTX diminished all the three phases. Conclusions: The results indicated that EFS stimulated adrenergic, cholinergic, and NANC neuroeffector systems simultaneously. Phase I was related to the NO pathway. Phase II was multiply affected by self-recovery property, adrenergic nerve and cholinergic nerve. Phase III was related to cholinergic nerve.
British Journal of Urology, 1996
To investigate the effects of pentoxifylline on penile blood flow and potency in patients with er... more To investigate the effects of pentoxifylline on penile blood flow and potency in patients with erectile dysfunction due to borderline arterial insufficiency. Following a routine diagnostic evaluation, 36 patients with borderline arterial disease diagnosed using penile duplex ultrasonography were included in the study. Of these patients, 20 (mean age 54 years, range 40-66) received 1.2 g of pentoxifylline daily, divided into three doses orally, for 2 months and 16 (mean age 54 years, range 34-65) received a placebo. Peak systolic velocities (PSVs) before and after the treatment were compared with those in patients receiving a placebo. The clinical improvement in erectile function was also evaluated. Twelve of 20 patients receiving pentoxifylline had an increase in PSV at the end of the treatment period. The mean change in PSV achieved by pentoxifylline treatment (6.25 cm/s) was significantly higher than that achieved by the placebo (0.38 cm/s). Seven patients had a positive response (successful coitus achieved after treatment with pentoxifylline). No serious side-effects occurred. Pentoxifylline was well tolerated and could increase penile arterial inflow, shown objectively as an increase in PSV on penile duplex ultrasonography. These findings should encourage further studies of the efficacy of pentoxifylline in the treatment of impotence.
Urologia Internationalis, 2010
Objective: The aim of this study was to investigate the impact of thioglycolic acid on normal ure... more Objective: The aim of this study was to investigate the impact of thioglycolic acid on normal urethral mucosa. Methods: Twenty-four rats were used. Three control and three study groups were formed each consisting of 4 rats. Controls groups were given 0.9% NaCl and study groups received thioglycolic acid instillation. The groups were allocated according to the time of urethral resection and the number of thioglycolic acid instillations (2, 4 or 8 instillations). The urethras of the rats were resected and examined under a light microscope in control and study groups 1, 2 and 3 on days 15, 30 and 60. Results: There was no difference in the urethral mucosa of rats in the study or control groups, and no differences were found when the study groups were compared to each of the other groups at the microscopic level. Conclusion: The application of thioglycolic acid is an easy and inexpensive way of clearing urethral hair and does not cause pathological changes in the normal urethral mucosa.
European Urology Supplements, 2009
The Journal of Trauma: Injury, Infection, and Critical Care, 1997
Urologic lesions accompanying pelvic fractures is a well-known entity, and reports on the correla... more Urologic lesions accompanying pelvic fractures is a well-known entity, and reports on the correlation of pediatric pelvic fracture type with lower urinary tract injury are few in the literature. We have reviewed 27 records and x-ray films of male pediatric patients who required urologic intervention after trauma to see which type of fracture, classified according to Tile, has a higher predilection of urologic injury. Most of the fractures that were considered to be mechanically stable and mainly localized to the anterior pelvic arch had urologic lesions that were generally confined to the bulbomembranous urethra (48%).
European Urology Supplements, 2010
the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have... more the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have maintained their penile length. conclusions: Prolonged ischemic priapism results in cavernosal fibrosis and a subsequent loss of penile length. The immediate insertion of a penile prosthesis in this situation is simple and maintains penile length. The complication rate is low and the subsequent outcome excellent.
Türk Üroloji Dergisi/Turkish Journal of Urology, 2014
Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologi... more Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologies. In this article, we report a a post-cesarean vesicouteri fistula with review of the literature.
Urologia Internationalis, 2006
Proteus syndrome is a rare hamartomatous disorder comprising a broad spectrum of congenital malfo... more Proteus syndrome is a rare hamartomatous disorder comprising a broad spectrum of congenital malformations and overgrowth of multiple tissues. Some rare urogenital malformations have been reported before. This case is unique for the presence of multiple genitourinary anomalies including retroperitoneal cystic mass, intra-abdominal testicle with hematoma and ureterovesical stricture apart from common clinic findings of proteus syndrome.
Urology, 2011
OBJECTIVES To assess the long-term results and efficiency of open reconstruction techniques for p... more OBJECTIVES To assess the long-term results and efficiency of open reconstruction techniques for pediatric and adolescent post-traumatic urethral strictures. METHODS A total of 75 patients who had undergone open reconstructive urethroplasty for post-traumatic bulbous or posterior urethral obliterative strictures resulting from pelvic fracture urethral injuries were retrospectively analyzed. The mean patient age was 12.3 years (range 6-17). Of the 75 patients, 38 had a bulbar stricture and 37 had posterior urethral obliteration. Perineal end-to-end anastomotic repair, urethral pull-through, and ureteral tube graft urethroplasty were performed in 54, 20, and 1 patient, respectively. All patients were followed up by medical history and a urinary flow rate evaluation at 6 and 12 months postoperatively. RESULTS The patients were followed up for 12-94 months (mean 43.2). The urethral strictures were successfully treated with end-to-end anastomotic urethroplasty in 37 (68.5%) of 54 patients, urethral pull-through urethroplasty in 14 (70%) of 20 patients, and ureteral tube graft in 1 patient. The total primary success rate was 69.3% (52 of 75 patients). Recurrent stricture developed in 23 patients. Of these 23 patients, 7 and 11 were successfully treated with secondary end-to-end anastomosis and direct vision internal urethrotomy, respectively. The overall success rate was 93.3% (70 of 75 patients). Five patients with treatment failure were still in follow-up, with direct vision urethrotomy performed, as needed. No penile curvature, penile shortening, or urethral diverticula developed. CONCLUSIONS The results of our study have shown that open urethral reconstruction techniques are effective for primary and secondary surgical interventions in pediatric and adolescent patients with post-traumatic urethral strictures in experienced centers. These techniques provide excellent long-term results with minimal morbidity. UROLOGY 77: 706-710, 2011.
Urology, 2007
OBJECTIVES To determine the role of the fistula characteristics on the outcomes of repair in uret... more OBJECTIVES To determine the role of the fistula characteristics on the outcomes of repair in urethrocutaneous fistulas that develop after hypospadias surgery. METHODS A total of 160 patients who had undergone urethrocutaneous fistula repair after hypospadias surgery were enrolled in this study. The prognostic significance of the site, size, and number of fistulas, number of the previous operations, and the techniques applied were analyzed by the appropriate statistical methods as the parameters of the study. RESULTS The fistulas were localized at the distal, mid, or proximal penile region in 69 (43.2%), 60 (37.5%), and 31 (19.2%) patients, respectively. No statistically significant relation was found between the fistula site and the success rate (P Ͼ0.05). The fistula size (2 mm or less versus greater than 2 mm) and the number of fistula repairs (single versus two or more) also did not affect the outcome (P Ͼ0.05, Pearson chi-square and Fisher's exact tests). CONCLUSIONS The site, size, and number of the fistula repair seemed to have no impact on the success rate. Well-known aspects of the modern hypospadias surgery (eg, delicate tissue handling, instruments, point coagulation, and vascularity of the tissues) probably play a role in the outcome. UROLOGY 69: 366-368, 2007.
Journal of Pediatric Urology, 2008
To determine the effect of Mathieu and tubularized incised plate (TIP) urethroplasty techniques o... more To determine the effect of Mathieu and tubularized incised plate (TIP) urethroplasty techniques on the outcome of repair in recurrent hypospadias. Material and methods: A total of 78 patients who had undergone surgical correction by either Mathieu or TIP urethroplasty after unsuccessful hypospadias surgery were enrolled in this study. Cases were divided into two groups according to the operation technique performed. Surgical success rate of the techniques and the prognostic significance of age, type of diversion used, caliber and length of new urethra, and the number of previous operations were analyzed statistically. Results: Mathieu and TIP urethroplasties were performed in 57 and 21 patients, respectively. No statistically significant relation was found between the groups for age, length of new urethra created, caliber of the urethra, urinary diversion used, mean operation success rates and number of previous operations. From within-group analysis, Mathieu urethroplasty was found to have a statistically significant relationship with the number of previous operations (P Z 0.025, ManneWhitney U-test). Conclusions: Age, length and caliber of new urethra, and diversion type used seem to have no effect on the success rate of Mathieu and TIP urethroplasty in recurrent hypospadias restoration. The success of the Mathieu operation diminished proportionally to the number of previous failed surgeries.
DergiPark (Istanbul University), Dec 3, 2019
Mesane taşı oluşumunda birçok etiyolojik sebep yer alabilir. Mesane içerisinde yabancı cisim varl... more Mesane taşı oluşumunda birçok etiyolojik sebep yer alabilir. Mesane içerisinde yabancı cisim varlığı bu nedenlerden biridir. Bu yazıda, daha önce çıkartılamayan bir üretral foley kateterin, balonunun patlatılarak çıkartılması neticesinde mesanede kalan artık bir lateks fragman üzerinde meydana gelmiş mesane taşlı bir olguyu sunuyoruz.
The New Journal of Urology, Oct 1, 2017
Kist hidatik, ekinokokkus granulosus'a bağlı olarak oluşan ve hayvancılıkla uğraşan toplumlar... more Kist hidatik, ekinokokkus granulosus'a bağlı olarak oluşan ve hayvancılıkla uğraşan toplumlarda sık görülen, genellikle karaciğer ve akciğer yerleşimli kistik bir hastalıktır. Bu hastalık seyrek olarak diğer organlar ve vücut boşluklarında da görülebilir. Biz bu yazıda izole retroperitoneal kist hidatikli bir olguyu sunuyoruzHydatid cyst is a cystic disease usually associated with liver and lung, which is common in societies engaged in animal husbandry due to echinococcus granulosus. This disease is rarely seen in other organs and body cavities. In this article we present a case of isolated retroperitoneal hydatid cys
Archivos espanoles de urologia, 2019
Archivos españoles de urología, 2019
Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologi... more Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologies. In this article, we report a a post- cesarean vesicouteri fistula with review of the literature.
Squamous cell carcinoma of the urinary tract is a very rarely encountered tumor. It is more frequ... more Squamous cell carcinoma of the urinary tract is a very rarely encountered tumor. It is more frequently reported in bladder and male urethra than in renal pelvis. With the addition of new cases in the literature, the impact of its features, such as the location and the stage of the tumor, on the outcome will be highlighted. Here, we present a case with renal squamous cell carcinoma located in the upper caliceal system and discuss it in the light of current literature. (Turk J Cancer 2002;32(1):20-24)
OZ Mesane tasi olusumunda bircok etiyolojik sebep yer alabilir. Mesane icerisinde yabanci cisim v... more OZ Mesane tasi olusumunda bircok etiyolojik sebep yer alabilir. Mesane icerisinde yabanci cisim varligi bu nedenlerden biridir. Bu yazida, daha once cikartilamayan bir uretral foley kateterin, balonunun patlatilarak cikartilmasi neticesinde mesanede kalan artik bir lateks fragman uzerinde meydana gelmis mesane tasli bir olguyu sunuyoruz.
Urolithiasis, 2016
the stones closer than 2 cm to the UPJ was 23.1 % for the pneumatic group versus 64 % for the las... more the stones closer than 2 cm to the UPJ was 23.1 % for the pneumatic group versus 64 % for the laser group (p < 0.01). Lithotripsy time was significantly longer in group-2 (16.48 ± 4.74 min) than group-1 (12.24 ± 3.95 min) (p < 0.01). Ho:YAG laser lithotripsy is more successful than pneumatic lithotripsy for upper ureteral stones and a retropulsion prevention device does not equalize the surgical success of Ho:YAG laser and pneumatic lithotripters for upper ureteral stones on the first postoperative day and one month after surgery. Although the success rate of the first month after surgery is higher in group-2, the difference is not statistically significant.
Turkiye Klinikleri Journal of Urology, 2014
In geriatric female patients with urinary incontinence, pelvic organ prolapse (POP) can also be r... more In geriatric female patients with urinary incontinence, pelvic organ prolapse (POP) can also be recognized during physical examination. Sometimes obliterative surgery may prefered instead of reconstructive surgical techniques in patients with serious comorbidities. We are reporting a 74-years-old patient with hemiplegia and stage 4 pelvic organ proplapse (POP-Q) who underwent colpocleisis as the surgical treatment. LeFort Colpocleisis technique can be used for POP teratment in geriatric patient groups and has high success rates. In this article, benefits and complications of this technique is disscussed under the light of literature.
European Urology Supplements, 2011
Materials & Methods: EFS was performed on phenylephrine (PhE) pre-contracted penile corpus cavern... more Materials & Methods: EFS was performed on phenylephrine (PhE) pre-contracted penile corpus cavernosum smooth muscle from male New Zealand White rabbits. The intrinsic nerves were field-stimulated electrically (voltage, 30 V; pulse duration, 1 ms; trains of pulses, 10 seconds; train interval, 3-5 min; frequency, 0.5-32 Hz). We also investigated the penile tracing elicited by EFS (voltage, 30 V; pulse duration, 1 ms; frequency, 8 Hz) on guanethidine (Guan), tetrodotoxin (TTX), Nω nitro-L-arginine-methyl ester (L-NAME), atropine or eserine pre-incubated tissues. results: We obtained consilient results from both models. Phase I was abolished by L-NAME. Phase II was significantly decreased by eserine and Guan but increased by L-NAME. Phase III was abolished by atropine but enhanced by eserine and Guan. TTX diminished all the three phases. Conclusions: The results indicated that EFS stimulated adrenergic, cholinergic, and NANC neuroeffector systems simultaneously. Phase I was related to the NO pathway. Phase II was multiply affected by self-recovery property, adrenergic nerve and cholinergic nerve. Phase III was related to cholinergic nerve.
British Journal of Urology, 1996
To investigate the effects of pentoxifylline on penile blood flow and potency in patients with er... more To investigate the effects of pentoxifylline on penile blood flow and potency in patients with erectile dysfunction due to borderline arterial insufficiency. Following a routine diagnostic evaluation, 36 patients with borderline arterial disease diagnosed using penile duplex ultrasonography were included in the study. Of these patients, 20 (mean age 54 years, range 40-66) received 1.2 g of pentoxifylline daily, divided into three doses orally, for 2 months and 16 (mean age 54 years, range 34-65) received a placebo. Peak systolic velocities (PSVs) before and after the treatment were compared with those in patients receiving a placebo. The clinical improvement in erectile function was also evaluated. Twelve of 20 patients receiving pentoxifylline had an increase in PSV at the end of the treatment period. The mean change in PSV achieved by pentoxifylline treatment (6.25 cm/s) was significantly higher than that achieved by the placebo (0.38 cm/s). Seven patients had a positive response (successful coitus achieved after treatment with pentoxifylline). No serious side-effects occurred. Pentoxifylline was well tolerated and could increase penile arterial inflow, shown objectively as an increase in PSV on penile duplex ultrasonography. These findings should encourage further studies of the efficacy of pentoxifylline in the treatment of impotence.
Urologia Internationalis, 2010
Objective: The aim of this study was to investigate the impact of thioglycolic acid on normal ure... more Objective: The aim of this study was to investigate the impact of thioglycolic acid on normal urethral mucosa. Methods: Twenty-four rats were used. Three control and three study groups were formed each consisting of 4 rats. Controls groups were given 0.9% NaCl and study groups received thioglycolic acid instillation. The groups were allocated according to the time of urethral resection and the number of thioglycolic acid instillations (2, 4 or 8 instillations). The urethras of the rats were resected and examined under a light microscope in control and study groups 1, 2 and 3 on days 15, 30 and 60. Results: There was no difference in the urethral mucosa of rats in the study or control groups, and no differences were found when the study groups were compared to each of the other groups at the microscopic level. Conclusion: The application of thioglycolic acid is an easy and inexpensive way of clearing urethral hair and does not cause pathological changes in the normal urethral mucosa.
European Urology Supplements, 2009
The Journal of Trauma: Injury, Infection, and Critical Care, 1997
Urologic lesions accompanying pelvic fractures is a well-known entity, and reports on the correla... more Urologic lesions accompanying pelvic fractures is a well-known entity, and reports on the correlation of pediatric pelvic fracture type with lower urinary tract injury are few in the literature. We have reviewed 27 records and x-ray films of male pediatric patients who required urologic intervention after trauma to see which type of fracture, classified according to Tile, has a higher predilection of urologic injury. Most of the fractures that were considered to be mechanically stable and mainly localized to the anterior pelvic arch had urologic lesions that were generally confined to the bulbomembranous urethra (48%).
European Urology Supplements, 2010
the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have... more the results of the surgery. 9 patients engaged in sexual intercourse regularly. All patients have maintained their penile length. conclusions: Prolonged ischemic priapism results in cavernosal fibrosis and a subsequent loss of penile length. The immediate insertion of a penile prosthesis in this situation is simple and maintains penile length. The complication rate is low and the subsequent outcome excellent.
Türk Üroloji Dergisi/Turkish Journal of Urology, 2014
Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologi... more Uterovesical fistulas are rare genitourinary fistulas developing secondary to iatrogenic etiologies. In this article, we report a a post-cesarean vesicouteri fistula with review of the literature.
Urologia Internationalis, 2006
Proteus syndrome is a rare hamartomatous disorder comprising a broad spectrum of congenital malfo... more Proteus syndrome is a rare hamartomatous disorder comprising a broad spectrum of congenital malformations and overgrowth of multiple tissues. Some rare urogenital malformations have been reported before. This case is unique for the presence of multiple genitourinary anomalies including retroperitoneal cystic mass, intra-abdominal testicle with hematoma and ureterovesical stricture apart from common clinic findings of proteus syndrome.
Urology, 2011
OBJECTIVES To assess the long-term results and efficiency of open reconstruction techniques for p... more OBJECTIVES To assess the long-term results and efficiency of open reconstruction techniques for pediatric and adolescent post-traumatic urethral strictures. METHODS A total of 75 patients who had undergone open reconstructive urethroplasty for post-traumatic bulbous or posterior urethral obliterative strictures resulting from pelvic fracture urethral injuries were retrospectively analyzed. The mean patient age was 12.3 years (range 6-17). Of the 75 patients, 38 had a bulbar stricture and 37 had posterior urethral obliteration. Perineal end-to-end anastomotic repair, urethral pull-through, and ureteral tube graft urethroplasty were performed in 54, 20, and 1 patient, respectively. All patients were followed up by medical history and a urinary flow rate evaluation at 6 and 12 months postoperatively. RESULTS The patients were followed up for 12-94 months (mean 43.2). The urethral strictures were successfully treated with end-to-end anastomotic urethroplasty in 37 (68.5%) of 54 patients, urethral pull-through urethroplasty in 14 (70%) of 20 patients, and ureteral tube graft in 1 patient. The total primary success rate was 69.3% (52 of 75 patients). Recurrent stricture developed in 23 patients. Of these 23 patients, 7 and 11 were successfully treated with secondary end-to-end anastomosis and direct vision internal urethrotomy, respectively. The overall success rate was 93.3% (70 of 75 patients). Five patients with treatment failure were still in follow-up, with direct vision urethrotomy performed, as needed. No penile curvature, penile shortening, or urethral diverticula developed. CONCLUSIONS The results of our study have shown that open urethral reconstruction techniques are effective for primary and secondary surgical interventions in pediatric and adolescent patients with post-traumatic urethral strictures in experienced centers. These techniques provide excellent long-term results with minimal morbidity. UROLOGY 77: 706-710, 2011.
Urology, 2007
OBJECTIVES To determine the role of the fistula characteristics on the outcomes of repair in uret... more OBJECTIVES To determine the role of the fistula characteristics on the outcomes of repair in urethrocutaneous fistulas that develop after hypospadias surgery. METHODS A total of 160 patients who had undergone urethrocutaneous fistula repair after hypospadias surgery were enrolled in this study. The prognostic significance of the site, size, and number of fistulas, number of the previous operations, and the techniques applied were analyzed by the appropriate statistical methods as the parameters of the study. RESULTS The fistulas were localized at the distal, mid, or proximal penile region in 69 (43.2%), 60 (37.5%), and 31 (19.2%) patients, respectively. No statistically significant relation was found between the fistula site and the success rate (P Ͼ0.05). The fistula size (2 mm or less versus greater than 2 mm) and the number of fistula repairs (single versus two or more) also did not affect the outcome (P Ͼ0.05, Pearson chi-square and Fisher's exact tests). CONCLUSIONS The site, size, and number of the fistula repair seemed to have no impact on the success rate. Well-known aspects of the modern hypospadias surgery (eg, delicate tissue handling, instruments, point coagulation, and vascularity of the tissues) probably play a role in the outcome. UROLOGY 69: 366-368, 2007.
Journal of Pediatric Urology, 2008
To determine the effect of Mathieu and tubularized incised plate (TIP) urethroplasty techniques o... more To determine the effect of Mathieu and tubularized incised plate (TIP) urethroplasty techniques on the outcome of repair in recurrent hypospadias. Material and methods: A total of 78 patients who had undergone surgical correction by either Mathieu or TIP urethroplasty after unsuccessful hypospadias surgery were enrolled in this study. Cases were divided into two groups according to the operation technique performed. Surgical success rate of the techniques and the prognostic significance of age, type of diversion used, caliber and length of new urethra, and the number of previous operations were analyzed statistically. Results: Mathieu and TIP urethroplasties were performed in 57 and 21 patients, respectively. No statistically significant relation was found between the groups for age, length of new urethra created, caliber of the urethra, urinary diversion used, mean operation success rates and number of previous operations. From within-group analysis, Mathieu urethroplasty was found to have a statistically significant relationship with the number of previous operations (P Z 0.025, ManneWhitney U-test). Conclusions: Age, length and caliber of new urethra, and diversion type used seem to have no effect on the success rate of Mathieu and TIP urethroplasty in recurrent hypospadias restoration. The success of the Mathieu operation diminished proportionally to the number of previous failed surgeries.