Kasim Abul-kasim - Academia.edu (original) (raw)

Papers by Kasim Abul-kasim

Acta Neurologica Belgica, 2011

Data concerning the persistent reduction of flow velocities measured by transcranial color-coded ... more Data concerning the persistent reduction of flow velocities measured by transcranial color-coded sonography (TCCS) in relation to the clinical and radiological outcome among patients with ischemic events in middle cerebral artery (MCA) territory is scarce. Patients with > or = 50% reduction of peak systolic velocities (PSV-MCA) as compared to the contralateral MCA were prospectively included in follow-up by TCCS (mean 404 days). Out of 849 patients with stroke admitted to our stroke unit, 25 patients showed reduced PSV-MCA and included in the analyses of this study. Ten (40%) survivors showed persistent reduction of PSV-MCA. None of the patients with normalized PSV-MCA suffered an ischemic event compared with three patients with persistent reduction of PSV-MCA (all had ipsilateral occlusion of the internal carotid artery caused by dissection). Patients with persistently reduced PSV-MCA exhibited significantly (Mann-Whitney test, p = 0.02) larger infarct volumes on CT (mean +/- SD...

Advanced radiological work-up as an adjunct to decision in early reconstructive surgery in brachi... more Advanced radiological work-up as an adjunct to decision in early reconstructive surgery in brachial plexus injuries

Background: To assess the reliability and to determine the sensitivity and specificity of Diffusi... more Background: To assess the reliability and to determine the sensitivity and specificity of Diffusion Weighted Images (DWI) in detection of acute infarcts in patients whose initial CT and conventional MR-sequences did not explain the patients stroke symptoms. The second aim was to find out if DWI provides additional information when it was performed within 2 days of onset of symptoms. Patients and methods: MRI and DWI of 59 consecutive patients [66 % were male; aged 60 ± 14 year (Mean ± SD)] admitted with stroke and stroke like episodes were retrospectively analyzed. The images were independently evaluated by two neuroradiologists. Results: DWI showed acute infarct in 25 patients (42 %). Hemiplegia and dizziness were the most common symptoms in patients with positive and negative DWI, respectively. Lacunar infarcts near the motor cortex were the most common type of infarcts detected by DWI. DWI provided additional information in 89 % of patients when performed within 2 days of ictus c...

Results, Line 10: "1 patients" -> "1 patient"

Spinal cord injury can be classified as traumatic and non-traumatic. The traumatic spinal cord in... more Spinal cord injury can be classified as traumatic and non-traumatic. The traumatic spinal cord injuries (SCI) are caused by motor vehicle accidents (56 %), falls (14 %), firearm and violence-related (16.6 %) and sports injuries (7 %) [1]. Injuries after falls and minor trauma are more commonly seen in elderly patients as they more often have spondylosis and osteoporosis. Violence is more common in urban populations while sports injuries are common in young individuals. About 68 % of children involved in spinal cord injuries caused by motor vehicle accidents were not wearing a seatbelt. Almost 80% of patients with spinal cord injury had multiple injuries [2]. Associated injuries include other bone fractures(29.3 %) and brain injury (11.5 %) [3]. Other causes of spinal cord injuries are non-traumatic and include the following: vascular disorders, degenerative disorders, spinal tumors, infectious and inflammatory conditions of the vertebral column with secondary SCI as well as iatrogen...

Purpose:To find out differences in cerebral blood volume (CBV) maps derived from dynamic suscepti... more Purpose:To find out differences in cerebral blood volume (CBV) maps derived from dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSCE-MRI) in glioblastomas and cerebral metastases. The main purpose was to compare CBV maps between metastases with different primary malignancies. Furthermore the metastasis group was compared with the glioblastoma group.Method:Conventional imaging and DSCE-MRI using 3T MRI system was performed in 114 patients, 38 glioblastomas and 76 metastases, 32 lung, 12 breast, 12 melanoma, 10 gastrointestinal (GI), and 10 other. CBV values were measured in the solid tumor area, peritumoral edema, area adjacent to peritumoral edema, and in normal apparent white matter in contralateral semioval center. The four subgroups of metastases were compared with one-way ANOVA to determine differences in CBV of significance. CBV values in glioblastomas and metastases were then statistically compared using paired t-test. Receiver -operating characteristic a...

Knowledge of interrater reliability in the evaluation of perfusion computed tomography (CTP) stud... more Knowledge of interrater reliability in the evaluation of perfusion computed tomography (CTP) studies is very limited even though the method is widely used in the workup of acute stroke. The aims of this study were to estimate the inter- and intraobserver agreement in the evaluation of CTP data and to evaluate the feasibility of the method. The CTP data of 20 consecutive patients (50% were females) aged 68+/-11 years with different categories of acute ischemic stroke were included in this retrospective analysis. Perfusion studies were evaluated independently by six radiologists on two different occasions. The overall inter- and intraobserver agreement was substantial, showing a capital KA, Cyrillic value of 0.65 (95% confidence interval 0.39-0.91). The time required for the post-processing and interpretation ranged from 37 to 460 seconds. Evaluation of manually post-processed CTP data according to the maximum slope model appears to be reliable. Experience and also a short training pe...

American Journal of Roentgenology

M. Söderberg was an application training consultant to Siemens Healthcare from 2013 through 2016.... more M. Söderberg was an application training consultant to Siemens Healthcare from 2013 through 2016. K. Lång receives travel grants and speaker fees from Siemens Healthcare. OBJECTIVE. Previous studies have shown the possibility to reduce radiation dose in abdominal CT by 25-50% without negatively affecting detection of liver lesions. How radiation dose reduction affects characterization of liver metastases is not as well known. The objective of this study was to investigate how different levels of simulated dose reduction affect the detection and characterization of liver lesions, primarily hypovascular metastases. A secondary objective was to analyze the relationship between the lesion size and contrast-to-noise ratio (CNR) and the detection rate. MATERIALS AND METHODS. Thirty-nine patients (19 with metastases and 20 without) were retrospectively selected. The following radiation dose levels (DLs) were simulated: 100% (reference level), 75%, 50%, and 25%. Five readers were asked to mark liver lesions and rate the probability of malignancy on a 5-grade Likert scale. Noninferiority analysis using the jackknife free-response ROC (JAFROC) method was performed as well as direct comparison of detection rates and grades. RESULTS. JAFROC analysis showed noninferior detection and characterization of metastases at DL75 as compared with DL100. However, the number of benign lesions and falsepositive localizations rated as "suspected malignancy" was significantly higher at DL75. CONCLUSION. Radiation dose can be reduced by 25% without negatively affecting diagnosis of hypovascular liver metastases. Characterization of benign lesions, however, is impaired at DL75, which may lead to unnecessary follow-up examinations. Finally, increased image noise seems to affect the detection of small lesions to a degree that cannot be explained solely by the reduction in CNR.

European Stroke Journal

Introduction While the relationship between hypertension and incident intracerebral haemorrhage i... more Introduction While the relationship between hypertension and incident intracerebral haemorrhage is well established, other risk factors are less clear. This study examined risk factors for primary intracerebral haemorrhage, separately for lobar and non-lobar intracerebral haemorrhage. Patients and methods Incidence of intracerebral haemorrhage was studied among 28,416 individuals from the population-based Malmö Diet and Cancer cohort. Intracerebral haemorrhage cases were ascertained using the Swedish Hospital Discharge Register and the Stroke Register of Malmö, validated by review of hospital records and images, and classified by location by a neuroradiologist. Multivariable Cox regression was used. Results Three hundred and thirty-three intracerebral haemorrhages occurred, mean follow-up time was 18.4 years. Systolic blood pressure (hazard ratio per 10 mmHg 1.19 [95% confidence interval 1.13–1.26], diastolic blood pressure (hazard ratio 1.42 [1.27–1.59]), oral anticoagulants (hazar...

Acta Radiologica

Background Residual tumor volume (RTV) and extent of resection (EOR) have previously been shown t... more Background Residual tumor volume (RTV) and extent of resection (EOR) have previously been shown to affect survival in glioblastoma (GB) patients. Quantitative radiological assessment (QRA) of these factors could potentially affect clinical decision-making in the postoperative period. Purpose The first aim was to evaluate the reproducibility of different volume estimation methods of RTV and EOR by comparing QRA with subjective visual estimation and with objective volume estimations. The second aim was to clarify whether QRA of RTV and EOR would provide accuracy in predicting progression-free survival (PFS) and overall survival (OS) in GB patients. Material and Methods Seventy GB patients were studied retrospectively. Reproducibility of QRA was compared to conventional visual analysis. Intra-rater agreement between two repeated measurements of 25 patients was calculated. QRA for RTV and EOR was made for the entire study population. Survival analysis was performed by multivariate cox-r...

Stroke, Oct 22, 2017

Raised plasma concentrations of tumor necrosis factor receptors (TNFR) have been linked to arteri... more Raised plasma concentrations of tumor necrosis factor receptors (TNFR) have been linked to arterial stiffness, cerebral microbleeds, and vascular events. The aim of this study was to investigate the association of circulating levels of TNFR1 and TNFR2 with risk for future intracerebral hemorrhage (ICH). The population-based MDCS cohort (Malmö Diet and Cancer Study; n=28 449) was conducted in 1991 to 1996. A nested case-control study was performed in the MDCS, including 220 cases who experienced ICH during the follow-up period (mean age at inclusion 62 years, 48% men) and 244 matched controls. Of the 220 ICH cases, 68 died within 28 days. Conditional logistic regression was used to study the association between plasma levels of TNFR1 and TNFR2 and incident ICH, adjusting for known ICH risk factors. Concentrations of both TNFR1 and TNFR2 were significantly higher in subjects who developed ICH during the follow-up. The associations remained after adjustment for ICH risk factors (TNFR1:...

Acta neurologica Belgica, 2010

7-year-old girl presented with a one-week history of diplopia. On examination, left abducens nerv... more 7-year-old girl presented with a one-week history of diplopia. On examination, left abducens nerve palsy was found. There was no clinical evidence of meningitis or of involvement of cranial nerves other than the abducens nerve. C-reactive protein and white blood cell count were normal. Magnetic resonance imaging (MRI) showed enhancement of 3 rd , 5 th , 6 th , and 12 th cranial nerves (Fig. 1); there were no focal brain lesions. Lumbar puncture showed monocytic pleocytosis and increased protein. CSF-Polymerase chain reaction was positive for Borrelia burgdorferi and negative for herpes simplex, varicella zoster, enterovirus and Epstein-Barr virus. Clinical improvement occurred after two weeks of intravenous treatment with Ceftriaxone 2 g per day. To our knowledge, there is no previous report on involvement of 6th and 12th cranial nerves in neuro borreliosis. Neuroborreliosis usually involves 3 rd , 5 th and 7 th cranial nerves (Hildenbrand et al., 2009); erythema migrans is present in 89 % of children (Sood et al., 2006). Our take home message is the following: as neuroborreliosis is a potentially treatable condition, this diagnosis should be considered whenever MRI shows multiple cranial nerve involve ment, despite the absence of clinical or labora tory evidence of active infection and despite involvement of some of the unusually involved cranial nerves.

Journal of oral & facial pain and headache, 2014

To examine (1) the occurrence of magnetic resonance imaging (MRI) signal changes in the painful r... more To examine (1) the occurrence of magnetic resonance imaging (MRI) signal changes in the painful regions of patients with atypical odontalgia (AO) and (2) the correlation of such findings to periapical bone defects detected with a comprehensive radiographic examination including cone beam computed tomography (CBCT). A total of 20 patients (mean age 52 years, range 34 to 65) diagnosed with AO participated. Mean pain intensity (± standard deviation) was 5.6 ± 1.8 on a 0-10 numerical rating scale, and mean pain duration was 4.3 ± 5.2 years. The inclusion criterion was chronic pain (> 6 months) located in a region with no clear pathologic cause identified clinically or in periapical radiographs. In addition to a clinical examination and a self-report questionnaire, the assessments included radiographic examinations (panoramic, periapical, and CBCT images), and an MRI examination. Changes in MRI signal in the painful region were recorded. Spearman's rank correlation between radiogr...

Background: Different diagnostic modalities to investigate atherosclerotic carotid artery disease... more Background: Different diagnostic modalities to investigate atherosclerotic carotid artery disease (ACAD) are nowadays available. The aim of this study was to test the concordance of the findings of the two most widely used diagnostic modalities namely computed tomography angiography (CTA) and doppler ultrasonography (DUS). Material and methods: 29 patients with acute ischemic stroke were subjected to CTA and DUS and included in this analysis; 17 patients were males (59 %). The mean age was 70.5 ± 8 years (Mean ± SD). The correlation and the degree of concordance between the findings of CTA and DUS were tested. The associations between the occurrence of ACAD and the degree of severity of stenosis with the age, the gender and the side of stenosis were also tested. The statistical significance was set to < 0.05. Results: This study showed almost perfect agreement between CTA and DUS in detection of stenosis with kappa value of 0.92 (95 % CI 0.82–1.02). Intraclass correlation coeffic...

Continuous implementation of new operative methods for correction and stabilization of spinal def... more Continuous implementation of new operative methods for correction and stabilization of spinal deformities in young patients with AIS demands a detailed morphological analysis of the vertebral column. CT spine according to protocols available in daily clinical practice means high radiation dose to these young individuals. All examinations included in this thesis were performed on a 16-slice CT scanner. Examination of the chest phantom in paper I showed that the radiation dose of the spine (including 15 vertebrae) was 20 times lower than that of routinely used protocols for CT examination of the spine in children (0.38 mSv vs 7.76 mSv). In paper II the radiation dose and the impact of dose reduction on image quality were evaluated in 113 consecutive examinations with low-dose spine CT and compared with that of 127 CTs after trauma and 15 CTs performed according to a previously used ANV-protocol of a limited part of the vertebral column. The effective dose of the low-dose spine CT (0.0...

Radiation Protection Dosimetry, 2010

Spinal deformities affect young individuals predominantly girls who are usually subjected to regu... more Spinal deformities affect young individuals predominantly girls who are usually subjected to regular and intensive radiological investigation especially before and after corrective surgery. Optimisation of spine computed tomography (CT) and the implementation of the low-dose CT in the work-up of spinal deformities were presented. The presented low-dose CT here means providing the operating surgeons with essential information about 15 vertebral bodies (almost 36-cm long region of the vertebral column). The mean effective dose of the low-dose CT was 0.37 mSv without any negative impact on image quality with regard to answering the clinical questions at issue. Tube current modulation (angular and longitudinal) has contributed to 19 % of the total dose reduction and soft tissue algorithm has helped to reduce the artefacts from the metal implants in the postoperative CTs.

Journal of orthopaedic surgery (Hong Kong)

To determine if the curve length, curve form, and location of the lower-end vertebra can identify... more To determine if the curve length, curve form, and location of the lower-end vertebra can identify the type of scoliosis. Methods. Standing posteroanterior and lateral radiographs of 78 women and 27 men with scoliosis aged 8 to 32 years were retrospectively analysed. Parameters measured were (1) the curve length (the number of vertebrae in the main curve), (2) the curve form (C-form, inverted C-form, or S-form), (3) the curve apex (the vertebral body at the apex of each curve), (4) the site of the scoliosis (thoracic, thoracolumbar, or lumbar), and (5) the location of the lower-end vertebra.

Acta neurologica Belgica

The Neuroradiology Journal, 2008