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Papers by Kavitha Jayavel

Journal of Pharmacy And Bioallied Sciences, 2020

Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients wit... more Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus (DM). Materials and Methods: The samples included in the study were divided into two groups: group A, comprises 50 patients with type 2 DM, and group B, comprises 30 subjects who were nondiabetic. A nonrandom consecutive sampling technique was used to enroll the subjects for the study. The χ2 test was used to examine the characteristics of the samples. Results: The results found that there is a significant difference in saliva and swab for Candida growth between patients with type 2 DM and normal healthy individuals. Swab had shown slightly more Candida growth than saliva in group A (type 2 DM). No significant variation in Candida growth was found. Candida krusei was seen in normal healthy individuals alone. In antifungal susceptibility pattern to various antifungal agents, Candida tropicalis has shown a significant result for various antifungal agents whereas Candida albicans and Candida dubliniensis did not show any significant result for various antifungal agents used in group A (patients with type 2 DM). Conclusion: Diabetic individuals who are prone to a hyperglycemic state favors the growth and establishment of Candida species. Although a smaller percentage of multidrug-resistant Candida species has been observed in the saliva of patients with type 2 DM.

International journal of orofacial biology, 2019

Nanotechnology is a rapidly growing field, focused on the creation of functional materials, devic... more Nanotechnology is a rapidly growing field, focused on the creation of functional materials, devices, and systems by controlling matter on a nanometer scale, and the utilization of novel phenomena and properties at that length scale. The application of nanotechnology in periodontology holds promise for the maintenance of comprehensive health care by using nanomaterials, including tissue engineering and nanorobots. A literature review was carried out on Google Scholar and PubMed about nanotechnology in periodontics, and the data have been taken from the selected articles and reviewed. This review gives an up-to-date view on nanotechnology, their role in diagnosis and management of periodontal diseases.

Archives Of Pharmacy Practice

Clinical Cancer Investigation Journal

Oral cancer is one of the most common types of cancer, and it is a big health issue, especially i... more Oral cancer is one of the most common types of cancer, and it is a big health issue, especially in developing countries. Even though science has come a long way in various ways, it is still one of the leading causes of death. In many developing countries, smoking and drinking alcohol seem to be the main things that cause oral cancer. Oral cancer (OC) is the most common type of cancer in India. It causes 50-70% of all cancer deaths and has the highest rate of occurrence among Asian countries. Most of the time, oral cancer affects the front of the tongue, the cheek, the floor of the mouth, the gums, or any other part of the mouth, including the palate, the lip, and the floor of the mouth. There are a lot of differences in how often oral cancer happens around the world. The biggest cause of oral disease-related deaths worldwide is estimated to be oral cancer, which is a serious health concern.

Medicine and Pharmacy Reports, 2022

The relationship between periodontitis (or periodontal disease) with Alzheimer’s disease has been... more The relationship between periodontitis (or periodontal disease) with Alzheimer’s disease has been reported by various primary sources in the past decade, but not with a solid secondary research statement. A systematic review and meta-analysis was conducted in accordance with the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and registered (Reference number: CRD42020185264) with PROSPERO (International prospective register for systematic reviews). A literature search was conducted on specific databases for suitable articles in English language. Out of 612 studies selected, 41 underwent full-text analysis; five studies were eligible for systematic review, and 3 for meta-analysis. Meta-analysis was performed with tests for sensitivity and statistical heterogeneity followed by calculation of summary effect measures in terms of odds ratio (OR) and 95% confidence interval (CI). The results of this review showed a significant associ...

International Journal of Orofacial Biology

One of the most common esthetic concern associated with the periodontal tissues is gingival reces... more One of the most common esthetic concern associated with the periodontal tissues is gingival recession. Gingival recession is the exposure of root surfaces due to apical migration of the gingival tissue margins; gingival margin migrates apical to the cementoenamel junction. Although it rarely results in tooth loss, marginal tissue recession is associated with thermal and tactile sensitivity, esthetic complaints, and a tendency toward root caries. This paper views the etiology, consequences, and the available surgical procedures for the coverage of exposed root surfaces, including two case reports.

Exophytic gingival lesions are frequently encountered in our day-to-day clinical practice. Of whi... more Exophytic gingival lesions are frequently encountered in our day-to-day clinical practice. Of which, Pyogenic granuloma is a relatively common, benign mucocutaneous lesion. The exact etiopathogenesis is unclear. Trauma, chronic inflammation, pregnancy are considered to be the possible etiological factors. The term ‘pyogenic granuloma’ is said to be a misnomer, because it is neither associated with pus formation nor a granulomatous lesion. Treatment consists of surgical excision along with eradicating the causative agents. Recurrence of the lesion can be prevented by complete excision of the lesion and by following proper oral hygiene measures. This article describe a case of pyogoenic granuloma in a 16year old female which have been successfully managed and maintained.

Dental Research Journal, 2010

Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem ... more Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem in anterior part of mouth because it will result in an unaesthetic pontic on a narrow hollowed out alveolar ridge. Yet, another problem is gingival recession and root exposure in adjacent teeth which represent a therapeutic problem to the clinician.Use of acellular dermal matrix graft is an appropriate solution to obtain root coverage in areas with localized or generalized soft tissue recessions, particularly if the recessions create aesthetic concern or root sensitivity or shallow root caries lesions. This case report describes a surgical technique using acellular dermal matrix graft on a class III ridge defect and Millers grade II gingival recessions.There was a gain in both bucco-lingual and apico-coronal dimensions of the ridge, in both height and width directions, when compared to baseline and after 3 months. Recession was also covered compared to the baseline condition.

The aim of this study was to clinically evaluate the treatment of Class I gingival recessions ass... more The aim of this study was to clinically evaluate the treatment of Class I gingival recessions associated with non carious cervical lesion by Coronally positioned flap alone and in combination with Resin Modified Glass Ionomer cement restoration. Twelve patients (24 sites) with bilateral Miller Class I gingival recessions were selected. The defects were randomly assigned to one of the treatments: Coronally positioned flap alone (control site) or Coronally positioned flap along with Resin Modified Glass Ionomer cement restoration (test site). The clinical parameters included were Width of the defect (WD), Depth of the defect (DD), Relative clinical attachment level (RCAL), Relative Gingival Recession (RGR), Height of Keratinized Tissue (HKT), Thickness of Keratinized Tissue (TKT), Plaque Index(PlI), Gingival Index (GI), Probing Depth (PD), Cervical lesion height in root surface (CLH R) and Dentin Sensitivity (DS). The measurements were taken before the surgery and first, third and six...

Dental Research Journal, 2010

Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem ... more Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem in anterior part of mouth because it will result in an unaesthetic pontic on a narrow hollowed out alveolar ridge. Yet, another problem is gingival recession and root exposure in adjacent teeth which represent a therapeutic problem to the clinician. Use of acellular dermal matrix graft is an appropriate solution to obtain root coverage in areas with localized or generalized soft tissue recessions, particularly if the recessions create aesthetic concern or root sensitivity or shallow root caries lesions. This case report describes a surgical technique using acellular dermal matrix graft on a class III ridge defect and Millers grade II gingival recessions. There was a gain in both bucco-lingual and apico-coronal dimensions of the ridge, in both height and width directions, when compared to baseline and after 3 months. Recession was also covered compared to the baseline condition.

Dental Research Journal, Mar 19, 2011

Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem ... more Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem in anterior part of mouth because it will result in an unaesthetic pontic on a narrow hollowed out alveolar ridge. Yet, another problem is gingival recession and root exposure in adjacent teeth which represent a therapeutic problem to the clinician. Use of acellular dermal matrix graft is an appropriate solution to obtain root coverage in areas with localized or generalized soft tissue recessions, particularly if the recessions create aesthetic concern or root sensitivity or shallow root caries lesions. This case report describes a surgical technique using acellular dermal matrix graft on a class III ridge defect and Millers grade II gingival recessions. There was a gain in both bucco-lingual and apico-coronal dimensions of the ridge, in both height and width directions, when compared to baseline and after 3 months. Recession was also covered compared to the baseline condition.

Journal of Pharmacy And Bioallied Sciences, 2020

Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients wit... more Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus (DM). Materials and Methods: The samples included in the study were divided into two groups: group A, comprises 50 patients with type 2 DM, and group B, comprises 30 subjects who were nondiabetic. A nonrandom consecutive sampling technique was used to enroll the subjects for the study. The χ2 test was used to examine the characteristics of the samples. Results: The results found that there is a significant difference in saliva and swab for Candida growth between patients with type 2 DM and normal healthy individuals. Swab had shown slightly more Candida growth than saliva in group A (type 2 DM). No significant variation in Candida growth was found. Candida krusei was seen in normal healthy individuals alone. In antifungal susceptibility pattern to various antifungal agents, Candida tropicalis has shown a significant result for various antifungal agents whereas Candida albicans and Candida dubliniensis did not show any significant result for various antifungal agents used in group A (patients with type 2 DM). Conclusion: Diabetic individuals who are prone to a hyperglycemic state favors the growth and establishment of Candida species. Although a smaller percentage of multidrug-resistant Candida species has been observed in the saliva of patients with type 2 DM.

International journal of orofacial biology, 2019

Nanotechnology is a rapidly growing field, focused on the creation of functional materials, devic... more Nanotechnology is a rapidly growing field, focused on the creation of functional materials, devices, and systems by controlling matter on a nanometer scale, and the utilization of novel phenomena and properties at that length scale. The application of nanotechnology in periodontology holds promise for the maintenance of comprehensive health care by using nanomaterials, including tissue engineering and nanorobots. A literature review was carried out on Google Scholar and PubMed about nanotechnology in periodontics, and the data have been taken from the selected articles and reviewed. This review gives an up-to-date view on nanotechnology, their role in diagnosis and management of periodontal diseases.

Archives Of Pharmacy Practice

Clinical Cancer Investigation Journal

Oral cancer is one of the most common types of cancer, and it is a big health issue, especially i... more Oral cancer is one of the most common types of cancer, and it is a big health issue, especially in developing countries. Even though science has come a long way in various ways, it is still one of the leading causes of death. In many developing countries, smoking and drinking alcohol seem to be the main things that cause oral cancer. Oral cancer (OC) is the most common type of cancer in India. It causes 50-70% of all cancer deaths and has the highest rate of occurrence among Asian countries. Most of the time, oral cancer affects the front of the tongue, the cheek, the floor of the mouth, the gums, or any other part of the mouth, including the palate, the lip, and the floor of the mouth. There are a lot of differences in how often oral cancer happens around the world. The biggest cause of oral disease-related deaths worldwide is estimated to be oral cancer, which is a serious health concern.

Medicine and Pharmacy Reports, 2022

The relationship between periodontitis (or periodontal disease) with Alzheimer’s disease has been... more The relationship between periodontitis (or periodontal disease) with Alzheimer’s disease has been reported by various primary sources in the past decade, but not with a solid secondary research statement. A systematic review and meta-analysis was conducted in accordance with the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and registered (Reference number: CRD42020185264) with PROSPERO (International prospective register for systematic reviews). A literature search was conducted on specific databases for suitable articles in English language. Out of 612 studies selected, 41 underwent full-text analysis; five studies were eligible for systematic review, and 3 for meta-analysis. Meta-analysis was performed with tests for sensitivity and statistical heterogeneity followed by calculation of summary effect measures in terms of odds ratio (OR) and 95% confidence interval (CI). The results of this review showed a significant associ...

International Journal of Orofacial Biology

One of the most common esthetic concern associated with the periodontal tissues is gingival reces... more One of the most common esthetic concern associated with the periodontal tissues is gingival recession. Gingival recession is the exposure of root surfaces due to apical migration of the gingival tissue margins; gingival margin migrates apical to the cementoenamel junction. Although it rarely results in tooth loss, marginal tissue recession is associated with thermal and tactile sensitivity, esthetic complaints, and a tendency toward root caries. This paper views the etiology, consequences, and the available surgical procedures for the coverage of exposed root surfaces, including two case reports.

Exophytic gingival lesions are frequently encountered in our day-to-day clinical practice. Of whi... more Exophytic gingival lesions are frequently encountered in our day-to-day clinical practice. Of which, Pyogenic granuloma is a relatively common, benign mucocutaneous lesion. The exact etiopathogenesis is unclear. Trauma, chronic inflammation, pregnancy are considered to be the possible etiological factors. The term ‘pyogenic granuloma’ is said to be a misnomer, because it is neither associated with pus formation nor a granulomatous lesion. Treatment consists of surgical excision along with eradicating the causative agents. Recurrence of the lesion can be prevented by complete excision of the lesion and by following proper oral hygiene measures. This article describe a case of pyogoenic granuloma in a 16year old female which have been successfully managed and maintained.

Dental Research Journal, 2010

Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem ... more Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem in anterior part of mouth because it will result in an unaesthetic pontic on a narrow hollowed out alveolar ridge. Yet, another problem is gingival recession and root exposure in adjacent teeth which represent a therapeutic problem to the clinician.Use of acellular dermal matrix graft is an appropriate solution to obtain root coverage in areas with localized or generalized soft tissue recessions, particularly if the recessions create aesthetic concern or root sensitivity or shallow root caries lesions. This case report describes a surgical technique using acellular dermal matrix graft on a class III ridge defect and Millers grade II gingival recessions.There was a gain in both bucco-lingual and apico-coronal dimensions of the ridge, in both height and width directions, when compared to baseline and after 3 months. Recession was also covered compared to the baseline condition.

The aim of this study was to clinically evaluate the treatment of Class I gingival recessions ass... more The aim of this study was to clinically evaluate the treatment of Class I gingival recessions associated with non carious cervical lesion by Coronally positioned flap alone and in combination with Resin Modified Glass Ionomer cement restoration. Twelve patients (24 sites) with bilateral Miller Class I gingival recessions were selected. The defects were randomly assigned to one of the treatments: Coronally positioned flap alone (control site) or Coronally positioned flap along with Resin Modified Glass Ionomer cement restoration (test site). The clinical parameters included were Width of the defect (WD), Depth of the defect (DD), Relative clinical attachment level (RCAL), Relative Gingival Recession (RGR), Height of Keratinized Tissue (HKT), Thickness of Keratinized Tissue (TKT), Plaque Index(PlI), Gingival Index (GI), Probing Depth (PD), Cervical lesion height in root surface (CLH R) and Dentin Sensitivity (DS). The measurements were taken before the surgery and first, third and six...

Dental Research Journal, 2010

Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem ... more Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem in anterior part of mouth because it will result in an unaesthetic pontic on a narrow hollowed out alveolar ridge. Yet, another problem is gingival recession and root exposure in adjacent teeth which represent a therapeutic problem to the clinician. Use of acellular dermal matrix graft is an appropriate solution to obtain root coverage in areas with localized or generalized soft tissue recessions, particularly if the recessions create aesthetic concern or root sensitivity or shallow root caries lesions. This case report describes a surgical technique using acellular dermal matrix graft on a class III ridge defect and Millers grade II gingival recessions. There was a gain in both bucco-lingual and apico-coronal dimensions of the ridge, in both height and width directions, when compared to baseline and after 3 months. Recession was also covered compared to the baseline condition.

Dental Research Journal, Mar 19, 2011

Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem ... more Excessive alveolar bone resorption is commonly found when teeth are extracted. This is a problem in anterior part of mouth because it will result in an unaesthetic pontic on a narrow hollowed out alveolar ridge. Yet, another problem is gingival recession and root exposure in adjacent teeth which represent a therapeutic problem to the clinician. Use of acellular dermal matrix graft is an appropriate solution to obtain root coverage in areas with localized or generalized soft tissue recessions, particularly if the recessions create aesthetic concern or root sensitivity or shallow root caries lesions. This case report describes a surgical technique using acellular dermal matrix graft on a class III ridge defect and Millers grade II gingival recessions. There was a gain in both bucco-lingual and apico-coronal dimensions of the ridge, in both height and width directions, when compared to baseline and after 3 months. Recession was also covered compared to the baseline condition.