Kazim Karaaslan - Academia.edu (original) (raw)

Papers by Kazim Karaaslan

Research paper thumbnail of Düşük akımlı anestezide izofluran ve desfluran ile vücut ağırlığına göre uygulanan taze gaz akımlarının karşılaştırılması

Türk anestezi ve reanimasyon dergisi, 2004

Research paper thumbnail of Recommendation for Resuming Elective Surgery during the Normalising Period in COVID-19 Pandemic

Turkish journal of anaesthesiology and reanimation, Feb 3, 2021

Zerrin Sungur1 , Jülide Ergil2 , Kazım Karaaslan3 , Yakup Tomak4 , Namigar Turgut5 , Ömer Kurtipe... more Zerrin Sungur1 , Jülide Ergil2 , Kazım Karaaslan3 , Yakup Tomak4 , Namigar Turgut5 , Ömer Kurtipek6 1Department of Anaesthesiology and Reanimation, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey 2Department of Anaesthesiology and Reanimation, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey 3Department of Anaesthesiology and Reanimation, Bezmialem Vakif University, İstanbul, Turkey 4Department of Anaesthesiology and Reanimation, Sakarya Training and Research Hospital, Sakarya, Turkey 5Department of Anaesthesiology and Reanimation, Prof. Dr. Cemil Taşçıoğlu Hospital, İstanbul, Turkey 6Department of Anaesthesiology and Reanimation, Gazi University Faculty of Medicine, Ankara, Turkey

Research paper thumbnail of Özofagus Duplikasyon Kisti: Çocuklarda Solunum Sıkıntısının Farklı Bir Nedeni

DergiPark (Istanbul University), Dec 1, 2008

Özofagus duplikasyon kistleri, çocuklarda görülen enterik kaynaklı nadir konjenital anomalilerden... more Özofagus duplikasyon kistleri, çocuklarda görülen enterik kaynaklı nadir konjenital anomalilerdendir. Gastrointestinal sistemin anormal kanalizasyonu sonucu oluşurlar. Klinik semptomlar genellikle kistin büyüklüğüne ve lokalizasyonuna bağlıdır. Forgut duplikasyon kistli bulunan çocuklar en sık solunum ile ilgili semptomlarla başvururlar. Bu çalışmada, solunum sıkıntısı bulunan iki forgut kisti olgusu sunulmuştur.

Research paper thumbnail of The successful management of an elderly Covid-19 infected patient by plasmapheresis

Transfusion and Apheresis Science, 2020

Research paper thumbnail of Anaesthesia and orphan disease

European Journal of Anaesthesiology, Dec 1, 2012

Research paper thumbnail of Esmolol Administration for the Treatment of Refractory Ventricular Fibrillation

Bezmialem science, Nov 2, 2016

Ventricular fibrillation (VF) after releasing an aortic cross clamp in patients undergoing open h... more Ventricular fibrillation (VF) after releasing an aortic cross clamp in patients undergoing open heart surgery procedures is not rare. Ischemia-reperfusion injury after release of the aortic clamp, increased adrenergic tone, and insufficient protection of the myocardium are the possible causes. Amiodarone, lidocaine, and beta blockers have been added to the cardioplegia solutions as a preventive measure for reperfusion VF. We report a case of life-threatening, shock-resistant VF during the weaning period of a cardiopulmonary bypass (CPB) in a 61-year-old male who underwent a mitral valve repair surgery for mitral valve regurgitation. After several defibrillation attempts, refractory VF was turned to normal sinus rhythm shortly after ultra-short acting, beta blocking agent esmolol administration. CPB was terminated successfully following this. In conclusion, VF is still a major problem for clinicians and the treatment of refractory VF is not well defined. In contrast with the absence of the sufficient randomized controlled human studies, theoretically beta blockers could be a choice alternative for shock refractory VF.

Research paper thumbnail of A new technique at insertion of laryngeal mask airway

European Journal of Anaesthesiology, Jun 1, 2013

Research paper thumbnail of Does smoking increase the anesthetic requirement?

Turkish Journal of Medical Sciences, Oct 24, 2019

Background/aim: To examine the effects of active and passive smoking on perioperative anesthetic ... more Background/aim: To examine the effects of active and passive smoking on perioperative anesthetic and analgesic consumption. Materials and methods: Patients were divided into three groups: group S, smokers; group PS, passive smokers; and group NS, individuals who did not have a history of smoking and were not exposed to smoke. All patients underwent the standard total intravenous anesthesia method. The primary endpoint of this study was determination of the total amount of propofol and remifentanil consumed. Results: The amount of propofol used in induction of anesthesia was significantly higher in group S compared to groups PS and NS. Moreover, the total consumption of propofol was significantly higher in group S compared to groups PS and NS. The total propofol consumption of group PS was significantly higher than that of group NS (P = 0.00). Analysis of total remifentanil consumption showed that remifentanil use was significantly higher in group S compared to group NS (P = 0.00). Conclusion: The amount of the anesthetic required to ensure equal anesthetic depth in similar surgeries was higher in active smokers and passive smokers compared to nonsmokers.

Research paper thumbnail of Anesthetic Management for a Patient With Transcatheter Mitral Valve Implantation

Journal of Cardiothoracic and Vascular Anesthesia, Feb 1, 2014

Research paper thumbnail of Tek taraflı akciğer ventilasyonunda ETViewTM trakeoskopik ventilasyon tüpü kullanımı

Türk Göğüs Kalp Damar Cerrahisi Dergisi, 2014

Research paper thumbnail of Paradoxal Air Embolism Occuring During Sitting Position in a Patient Without an Intracardiac Defect

Journal of Cardio-Vascular-Thoracic Anaesthesia and Intensive Care Society, 2015

Sitting position is widely used in neurosurgery. One disadvantage of this position is a negative ... more Sitting position is widely used in neurosurgery. One disadvantage of this position is a negative pressure in cranial veins in the sitting position that leads to air embolism. The most common cause is intracardiac shunting induced by patent foramen ovale, and it can be determined by transesophageal echocardiography (TEE). However, rarely, paradoxical air embolism (PAE) can occur through intrapulmonary functional arteriovenous anastomoses developing during anesthesia. The aim of this paper is to increase awareness about development of PAE which can occur through intrapulmonary shunt aggravated by hypoxia in cases with high incidencerates of VAE (venous air embolism).

Research paper thumbnail of A new maneuver for classical laryngeal mask airway insertion: Prospective randomized study

Journal of Surgery and Medicine

Background/Aim: Laryngeal mask airway (LMA) has been frequently used for airway management. But t... more Background/Aim: Laryngeal mask airway (LMA) has been frequently used for airway management. But the satisfaction of the insertion and trauma at insertion remain problems. We present a new insertion maneuver for classical LMA (cLMA) with a partially inflated cuff and examine its success and complication rate. Methods: In 4 months, 158 patients who were classified as ASA I–III and older than 18 years old and were planned for LMA were included in this study consecutively (according to the study design, one patient was excluded during the study). Emergency cases, patients with any contraindications with LMA, patients who were expected to undergo surgery for more than 2 h, patients with preoperative respiratory tract infection or sore throat, patients undergoing oral or nasal surgery, and patients with aspirated oropharyngeal secretions after removal of LMA was excluded from the study. Age, gender, height, weight, ASA scores, comorbidities, and the duration of anesthesia and surgery of t...

Research paper thumbnail of Anesteziyoloji ve COVID-19 - 2020

Research paper thumbnail of Salivary Duct Carcinoma of the Parotid Gland: A Case Report

Tükürük bezi duktal karsinomu yaygın servikal lenf nodu tutulumu ve uzak metastaz ile karakterize... more Tükürük bezi duktal karsinomu yaygın servikal lenf nodu tutulumu ve uzak metastaz ile karakterize oldukça agresif bir tümördür. Hastaların büyük çoğunluğunu 50 yaş veya üzeri erkek olgular oluşturur. Genellikle fasiyal paralizinin eşlik ettiği, hızlı büyüyen, ağrılı sert bir kitle olarak ortaya çıkan duktal karsinomun tedavisi cerrahidir. Total parotidektomi, boyun diseksiyonu ve postoperatif radyoterapi bu tümörün lokal ve bölgesel kontrolünde uygun bir tedavi seçeneği olarak görülmektedir. Agresif tedaviye rağmen prognoz çok kötüdür. Uzak metastaz oranı % 46 ile % 66, ölüm oranı ise % 60 ile % 75 arasında değişmektedir. Bu yazıda 67 yaşında erkek hastada parotis bezi duktal karsinomu olgusu sunulmuştur. Hastalığın hem ayırıcı tanısı hem de cerrahi tedavi seçenekleri sunulmuş ve literatür gözden geçirilmiştir.

Research paper thumbnail of COVID-19 Hastaları İçin Yoğun Bakım Organizasyonu, Kabul Kriterleri ve Çalışan Güvenliği

Türkiye Klinikleri COVID - 19, 2020

Research paper thumbnail of Comparison of serratus plane block alone and in combination with pectoral type 1 block for breast cancer surgery: a randomized controlled study

PubMed, 2021

Background/aim: Concurrent application of ultrasound-guided pectoral type 1 (PECS I) and serratus... more Background/aim: Concurrent application of ultrasound-guided pectoral type 1 (PECS I) and serratus plane block (SPB) is one of the most appropriate multimodal analgesic strategies for reducing acute post-mastectomy pain. The purpose of the present study was to compare the analgesic efficacy of SPB alone, or in combination with PECS I block for post-mastectomy pain following breast cancer surgery. Materials and methods: Sixty participants undergoing breast cancer surgery were randomly assigned to two groups. After anesthesia induction, group S (n =30) received SPB alone, whereas the SPECS group (n =30) received a combination of PECS I and SPB. Pain scores at 0, 1, 2, 6, 12, 24 h postoperatively, intra-operative fentanyl consumption, postoperative time to first rescue analgesia, nausea, vomiting, patient satisfaction, and anesthesia-related complications were recorded. Results: Pain scores in the SPECS group were significantly lower than group S throughout the follow-up period (p <0.001). A significant reduction in postoperative rescue morphine consumption (p =0.01, median difference 7 mg, 95 % confidence interval: 5.1-7.9 mg) and intraoperative fentanyl consumption (p =0.01) in the SPECS group compared with group S. Moreover, postoperative nausea and vomiting were lower, and patient satisfaction was higher in the SPECS group compared with that of the group S. Conclusions: These results suggest that SPB application and PECS I provide more effective and reliable perioperative analgesia and increase patient satisfaction in breast cancer surgery. HIPPOKRATIA 2021, 25 (1):8-14. Trial registration number: NCT03899545.

Research paper thumbnail of Giant Mucocele of the Maxillary Sinus: A Case Report

KBB-Forum: Elektronik Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi, Apr 1, 2008

Research paper thumbnail of Abstract PR412

Anesthesia & Analgesia, Sep 1, 2016

Background & Objectives: Fluid and electrolyte imbalances are extremely common problems in th... more Background & Objectives: Fluid and electrolyte imbalances are extremely common problems in the perioperative period. Intraoperative goal directed fluid therapy has been shown to reduce the mortality, duration of hospitalization and intensive care unit requirement. The goal directed fluid therapy is critical for the improvement of outcome of the management in the postoperative period.Several static and dynamic measurements are used to assess the intravascular volume status. Dynamic measurements are known to be more sensitive for predicting fluid responsiveness especially patients under mechanical ventilation whereas static measurements are known to be low predictive. In this study we aimed to identify which methods are more predictable to determine the intravascular volume status.

Research paper thumbnail of Comparison of ultrasound-guided transversus abdominis plane block, quadratus lumborum block, and caudal epidural block for perioperative analgesia in pediatric lower abdominal surgery

Turkish Journal of Medical Sciences, Oct 24, 2019

Introduction Recently, regional anesthesia techniques have been replaced by peripheral nerve bloc... more Introduction Recently, regional anesthesia techniques have been replaced by peripheral nerve blocks in the management of perioperative pain. Because of the widespread use of ultrasonography, it has been reported that peripheral nerve blocks showed similar analgesic efficacy with favorable rates of side effects when compared to central blocks. Central nerve blocks are often used in combination with general anesthesia for pediatric surgery in order to reduce general anesthetic requirements, opioid use, postoperative pain, nausea and vomiting, and risk of anesthetic neurotoxicity, particularly in young patients [1-4]. Caudal epidural block (CEB) is a well-established and commonly performed neuraxial technique for providing intraoperative and postoperative analgesia in pediatric patients scheduled for lower abdominal perineal surgical interventions [5-6]. Although the efficacy and safety of CEB are fairly high [7], the associated complications such as inadvertent dural puncture, unwarranted motor blockade of lower limbs, and disturbance of bladder function [8] might limit its use. Undoubtedly, introduction of ultrasonography into anesthesia practice has led to an increase in practice of peripheral nerve blocks. Ultrasonography guidance has significantly facilitated the practice of regional nerve blockades [9]. There has been a growing interest in ultrasound-guided transversus abdominis plane (TAP) block as an alternative and valid postoperative analgesic method in pediatric patients undergoing lower abdominal surgery [10]. Quadratus lumborum block (QL block) is a new abdominal and truncal block used for providing somatic Background/aim: Despite different regional anesthesia techniques used to provide intraoperative and postoperative analgesia in pediatric patients, the analgesic effectiveness of peripheral nerve blockades with minimal side effect profiles have not yet been fully determined. We aimed to compare the efficacy of ultrasound-guided transversus abdominis plane (TAP) block, quadratus lumborum (QL) block, and caudal epidural block on perioperative analgesia in pediatric patients aged between 6 months and 14 years who underwent elective unilateral lower abdominal wall surgery. Materials and methods: Ninety-four patients classified under the American Society of Anesthesiologists physical status classification system as ASA I or ASA II were randomly divided into 3 equal groups to perform TAP, QL or Caudal epidural block using 0.25% of bupivacaine solution (0.5 ml kg −1). Results: Postoperative analgesic consumption was highest in the TAP block group (P < 0.05). In the QL block group, Pediatric Objective Pain Scale (POAS) scores were statistically significantly lower after 2 and 4 h (P < 0.05). The length of hospital stay was significantly longer in the caudal block group than the QL block group (P < 0.05). Conclusion: We suggest that analgesia with ultrasound-guided QL block should be considered as an option for perioperative analgesia in pediatric patients undergoing lower abdominal surgery if the expertise and equipment are available.

Research paper thumbnail of Comparison of dexmedetomidine and midazolam for monitored anesthesia care combined with tramadol via patient-controlled analgesia in endoscopic nasal surgery: A prospective, randomized, double-blind, clinical study

Current Therapeutic Research-clinical and Experimental, Mar 1, 2007

Background: Monitored anesthesia care (MAC) may be applied for septoplasty or endoscopic sinus su... more Background: Monitored anesthesia care (MAC) may be applied for septoplasty or endoscopic sinus surgery in which an adequate sedation and analgesia without respiratory depression are desired for comfort of both the patient and the surgeon. Several combinations with different agents have been used for this purpose in these patients. However, analgesic properties for these agents have not been reported. Objective: The aim of this study was to investigate the analgesic and sedative effects of dexmedetomidine or midazolam infusion combined with tramadol that was used via patient-controlled analgesia (PCA), and to document the effects of these drugs on early cognitive functions. Methods: This prospective, randomized, double-blind, clinical study enrolled patients undergoing septoplasty or endoscopic sinus surgery at the

Research paper thumbnail of Düşük akımlı anestezide izofluran ve desfluran ile vücut ağırlığına göre uygulanan taze gaz akımlarının karşılaştırılması

Türk anestezi ve reanimasyon dergisi, 2004

Research paper thumbnail of Recommendation for Resuming Elective Surgery during the Normalising Period in COVID-19 Pandemic

Turkish journal of anaesthesiology and reanimation, Feb 3, 2021

Zerrin Sungur1 , Jülide Ergil2 , Kazım Karaaslan3 , Yakup Tomak4 , Namigar Turgut5 , Ömer Kurtipe... more Zerrin Sungur1 , Jülide Ergil2 , Kazım Karaaslan3 , Yakup Tomak4 , Namigar Turgut5 , Ömer Kurtipek6 1Department of Anaesthesiology and Reanimation, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey 2Department of Anaesthesiology and Reanimation, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey 3Department of Anaesthesiology and Reanimation, Bezmialem Vakif University, İstanbul, Turkey 4Department of Anaesthesiology and Reanimation, Sakarya Training and Research Hospital, Sakarya, Turkey 5Department of Anaesthesiology and Reanimation, Prof. Dr. Cemil Taşçıoğlu Hospital, İstanbul, Turkey 6Department of Anaesthesiology and Reanimation, Gazi University Faculty of Medicine, Ankara, Turkey

Research paper thumbnail of Özofagus Duplikasyon Kisti: Çocuklarda Solunum Sıkıntısının Farklı Bir Nedeni

DergiPark (Istanbul University), Dec 1, 2008

Özofagus duplikasyon kistleri, çocuklarda görülen enterik kaynaklı nadir konjenital anomalilerden... more Özofagus duplikasyon kistleri, çocuklarda görülen enterik kaynaklı nadir konjenital anomalilerdendir. Gastrointestinal sistemin anormal kanalizasyonu sonucu oluşurlar. Klinik semptomlar genellikle kistin büyüklüğüne ve lokalizasyonuna bağlıdır. Forgut duplikasyon kistli bulunan çocuklar en sık solunum ile ilgili semptomlarla başvururlar. Bu çalışmada, solunum sıkıntısı bulunan iki forgut kisti olgusu sunulmuştur.

Research paper thumbnail of The successful management of an elderly Covid-19 infected patient by plasmapheresis

Transfusion and Apheresis Science, 2020

Research paper thumbnail of Anaesthesia and orphan disease

European Journal of Anaesthesiology, Dec 1, 2012

Research paper thumbnail of Esmolol Administration for the Treatment of Refractory Ventricular Fibrillation

Bezmialem science, Nov 2, 2016

Ventricular fibrillation (VF) after releasing an aortic cross clamp in patients undergoing open h... more Ventricular fibrillation (VF) after releasing an aortic cross clamp in patients undergoing open heart surgery procedures is not rare. Ischemia-reperfusion injury after release of the aortic clamp, increased adrenergic tone, and insufficient protection of the myocardium are the possible causes. Amiodarone, lidocaine, and beta blockers have been added to the cardioplegia solutions as a preventive measure for reperfusion VF. We report a case of life-threatening, shock-resistant VF during the weaning period of a cardiopulmonary bypass (CPB) in a 61-year-old male who underwent a mitral valve repair surgery for mitral valve regurgitation. After several defibrillation attempts, refractory VF was turned to normal sinus rhythm shortly after ultra-short acting, beta blocking agent esmolol administration. CPB was terminated successfully following this. In conclusion, VF is still a major problem for clinicians and the treatment of refractory VF is not well defined. In contrast with the absence of the sufficient randomized controlled human studies, theoretically beta blockers could be a choice alternative for shock refractory VF.

Research paper thumbnail of A new technique at insertion of laryngeal mask airway

European Journal of Anaesthesiology, Jun 1, 2013

Research paper thumbnail of Does smoking increase the anesthetic requirement?

Turkish Journal of Medical Sciences, Oct 24, 2019

Background/aim: To examine the effects of active and passive smoking on perioperative anesthetic ... more Background/aim: To examine the effects of active and passive smoking on perioperative anesthetic and analgesic consumption. Materials and methods: Patients were divided into three groups: group S, smokers; group PS, passive smokers; and group NS, individuals who did not have a history of smoking and were not exposed to smoke. All patients underwent the standard total intravenous anesthesia method. The primary endpoint of this study was determination of the total amount of propofol and remifentanil consumed. Results: The amount of propofol used in induction of anesthesia was significantly higher in group S compared to groups PS and NS. Moreover, the total consumption of propofol was significantly higher in group S compared to groups PS and NS. The total propofol consumption of group PS was significantly higher than that of group NS (P = 0.00). Analysis of total remifentanil consumption showed that remifentanil use was significantly higher in group S compared to group NS (P = 0.00). Conclusion: The amount of the anesthetic required to ensure equal anesthetic depth in similar surgeries was higher in active smokers and passive smokers compared to nonsmokers.

Research paper thumbnail of Anesthetic Management for a Patient With Transcatheter Mitral Valve Implantation

Journal of Cardiothoracic and Vascular Anesthesia, Feb 1, 2014

Research paper thumbnail of Tek taraflı akciğer ventilasyonunda ETViewTM trakeoskopik ventilasyon tüpü kullanımı

Türk Göğüs Kalp Damar Cerrahisi Dergisi, 2014

Research paper thumbnail of Paradoxal Air Embolism Occuring During Sitting Position in a Patient Without an Intracardiac Defect

Journal of Cardio-Vascular-Thoracic Anaesthesia and Intensive Care Society, 2015

Sitting position is widely used in neurosurgery. One disadvantage of this position is a negative ... more Sitting position is widely used in neurosurgery. One disadvantage of this position is a negative pressure in cranial veins in the sitting position that leads to air embolism. The most common cause is intracardiac shunting induced by patent foramen ovale, and it can be determined by transesophageal echocardiography (TEE). However, rarely, paradoxical air embolism (PAE) can occur through intrapulmonary functional arteriovenous anastomoses developing during anesthesia. The aim of this paper is to increase awareness about development of PAE which can occur through intrapulmonary shunt aggravated by hypoxia in cases with high incidencerates of VAE (venous air embolism).

Research paper thumbnail of A new maneuver for classical laryngeal mask airway insertion: Prospective randomized study

Journal of Surgery and Medicine

Background/Aim: Laryngeal mask airway (LMA) has been frequently used for airway management. But t... more Background/Aim: Laryngeal mask airway (LMA) has been frequently used for airway management. But the satisfaction of the insertion and trauma at insertion remain problems. We present a new insertion maneuver for classical LMA (cLMA) with a partially inflated cuff and examine its success and complication rate. Methods: In 4 months, 158 patients who were classified as ASA I–III and older than 18 years old and were planned for LMA were included in this study consecutively (according to the study design, one patient was excluded during the study). Emergency cases, patients with any contraindications with LMA, patients who were expected to undergo surgery for more than 2 h, patients with preoperative respiratory tract infection or sore throat, patients undergoing oral or nasal surgery, and patients with aspirated oropharyngeal secretions after removal of LMA was excluded from the study. Age, gender, height, weight, ASA scores, comorbidities, and the duration of anesthesia and surgery of t...

Research paper thumbnail of Anesteziyoloji ve COVID-19 - 2020

Research paper thumbnail of Salivary Duct Carcinoma of the Parotid Gland: A Case Report

Tükürük bezi duktal karsinomu yaygın servikal lenf nodu tutulumu ve uzak metastaz ile karakterize... more Tükürük bezi duktal karsinomu yaygın servikal lenf nodu tutulumu ve uzak metastaz ile karakterize oldukça agresif bir tümördür. Hastaların büyük çoğunluğunu 50 yaş veya üzeri erkek olgular oluşturur. Genellikle fasiyal paralizinin eşlik ettiği, hızlı büyüyen, ağrılı sert bir kitle olarak ortaya çıkan duktal karsinomun tedavisi cerrahidir. Total parotidektomi, boyun diseksiyonu ve postoperatif radyoterapi bu tümörün lokal ve bölgesel kontrolünde uygun bir tedavi seçeneği olarak görülmektedir. Agresif tedaviye rağmen prognoz çok kötüdür. Uzak metastaz oranı % 46 ile % 66, ölüm oranı ise % 60 ile % 75 arasında değişmektedir. Bu yazıda 67 yaşında erkek hastada parotis bezi duktal karsinomu olgusu sunulmuştur. Hastalığın hem ayırıcı tanısı hem de cerrahi tedavi seçenekleri sunulmuş ve literatür gözden geçirilmiştir.

Research paper thumbnail of COVID-19 Hastaları İçin Yoğun Bakım Organizasyonu, Kabul Kriterleri ve Çalışan Güvenliği

Türkiye Klinikleri COVID - 19, 2020

Research paper thumbnail of Comparison of serratus plane block alone and in combination with pectoral type 1 block for breast cancer surgery: a randomized controlled study

PubMed, 2021

Background/aim: Concurrent application of ultrasound-guided pectoral type 1 (PECS I) and serratus... more Background/aim: Concurrent application of ultrasound-guided pectoral type 1 (PECS I) and serratus plane block (SPB) is one of the most appropriate multimodal analgesic strategies for reducing acute post-mastectomy pain. The purpose of the present study was to compare the analgesic efficacy of SPB alone, or in combination with PECS I block for post-mastectomy pain following breast cancer surgery. Materials and methods: Sixty participants undergoing breast cancer surgery were randomly assigned to two groups. After anesthesia induction, group S (n =30) received SPB alone, whereas the SPECS group (n =30) received a combination of PECS I and SPB. Pain scores at 0, 1, 2, 6, 12, 24 h postoperatively, intra-operative fentanyl consumption, postoperative time to first rescue analgesia, nausea, vomiting, patient satisfaction, and anesthesia-related complications were recorded. Results: Pain scores in the SPECS group were significantly lower than group S throughout the follow-up period (p <0.001). A significant reduction in postoperative rescue morphine consumption (p =0.01, median difference 7 mg, 95 % confidence interval: 5.1-7.9 mg) and intraoperative fentanyl consumption (p =0.01) in the SPECS group compared with group S. Moreover, postoperative nausea and vomiting were lower, and patient satisfaction was higher in the SPECS group compared with that of the group S. Conclusions: These results suggest that SPB application and PECS I provide more effective and reliable perioperative analgesia and increase patient satisfaction in breast cancer surgery. HIPPOKRATIA 2021, 25 (1):8-14. Trial registration number: NCT03899545.

Research paper thumbnail of Giant Mucocele of the Maxillary Sinus: A Case Report

KBB-Forum: Elektronik Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi, Apr 1, 2008

Research paper thumbnail of Abstract PR412

Anesthesia & Analgesia, Sep 1, 2016

Background & Objectives: Fluid and electrolyte imbalances are extremely common problems in th... more Background & Objectives: Fluid and electrolyte imbalances are extremely common problems in the perioperative period. Intraoperative goal directed fluid therapy has been shown to reduce the mortality, duration of hospitalization and intensive care unit requirement. The goal directed fluid therapy is critical for the improvement of outcome of the management in the postoperative period.Several static and dynamic measurements are used to assess the intravascular volume status. Dynamic measurements are known to be more sensitive for predicting fluid responsiveness especially patients under mechanical ventilation whereas static measurements are known to be low predictive. In this study we aimed to identify which methods are more predictable to determine the intravascular volume status.

Research paper thumbnail of Comparison of ultrasound-guided transversus abdominis plane block, quadratus lumborum block, and caudal epidural block for perioperative analgesia in pediatric lower abdominal surgery

Turkish Journal of Medical Sciences, Oct 24, 2019

Introduction Recently, regional anesthesia techniques have been replaced by peripheral nerve bloc... more Introduction Recently, regional anesthesia techniques have been replaced by peripheral nerve blocks in the management of perioperative pain. Because of the widespread use of ultrasonography, it has been reported that peripheral nerve blocks showed similar analgesic efficacy with favorable rates of side effects when compared to central blocks. Central nerve blocks are often used in combination with general anesthesia for pediatric surgery in order to reduce general anesthetic requirements, opioid use, postoperative pain, nausea and vomiting, and risk of anesthetic neurotoxicity, particularly in young patients [1-4]. Caudal epidural block (CEB) is a well-established and commonly performed neuraxial technique for providing intraoperative and postoperative analgesia in pediatric patients scheduled for lower abdominal perineal surgical interventions [5-6]. Although the efficacy and safety of CEB are fairly high [7], the associated complications such as inadvertent dural puncture, unwarranted motor blockade of lower limbs, and disturbance of bladder function [8] might limit its use. Undoubtedly, introduction of ultrasonography into anesthesia practice has led to an increase in practice of peripheral nerve blocks. Ultrasonography guidance has significantly facilitated the practice of regional nerve blockades [9]. There has been a growing interest in ultrasound-guided transversus abdominis plane (TAP) block as an alternative and valid postoperative analgesic method in pediatric patients undergoing lower abdominal surgery [10]. Quadratus lumborum block (QL block) is a new abdominal and truncal block used for providing somatic Background/aim: Despite different regional anesthesia techniques used to provide intraoperative and postoperative analgesia in pediatric patients, the analgesic effectiveness of peripheral nerve blockades with minimal side effect profiles have not yet been fully determined. We aimed to compare the efficacy of ultrasound-guided transversus abdominis plane (TAP) block, quadratus lumborum (QL) block, and caudal epidural block on perioperative analgesia in pediatric patients aged between 6 months and 14 years who underwent elective unilateral lower abdominal wall surgery. Materials and methods: Ninety-four patients classified under the American Society of Anesthesiologists physical status classification system as ASA I or ASA II were randomly divided into 3 equal groups to perform TAP, QL or Caudal epidural block using 0.25% of bupivacaine solution (0.5 ml kg −1). Results: Postoperative analgesic consumption was highest in the TAP block group (P < 0.05). In the QL block group, Pediatric Objective Pain Scale (POAS) scores were statistically significantly lower after 2 and 4 h (P < 0.05). The length of hospital stay was significantly longer in the caudal block group than the QL block group (P < 0.05). Conclusion: We suggest that analgesia with ultrasound-guided QL block should be considered as an option for perioperative analgesia in pediatric patients undergoing lower abdominal surgery if the expertise and equipment are available.

Research paper thumbnail of Comparison of dexmedetomidine and midazolam for monitored anesthesia care combined with tramadol via patient-controlled analgesia in endoscopic nasal surgery: A prospective, randomized, double-blind, clinical study

Current Therapeutic Research-clinical and Experimental, Mar 1, 2007

Background: Monitored anesthesia care (MAC) may be applied for septoplasty or endoscopic sinus su... more Background: Monitored anesthesia care (MAC) may be applied for septoplasty or endoscopic sinus surgery in which an adequate sedation and analgesia without respiratory depression are desired for comfort of both the patient and the surgeon. Several combinations with different agents have been used for this purpose in these patients. However, analgesic properties for these agents have not been reported. Objective: The aim of this study was to investigate the analgesic and sedative effects of dexmedetomidine or midazolam infusion combined with tramadol that was used via patient-controlled analgesia (PCA), and to document the effects of these drugs on early cognitive functions. Methods: This prospective, randomized, double-blind, clinical study enrolled patients undergoing septoplasty or endoscopic sinus surgery at the