Kelsey Hudson - Academia.edu (original) (raw)

Papers by Kelsey Hudson

Research paper thumbnail of Positivity and Negativity in Interparental Conflict: Links with Children’s Evaluations and Appraisals

Journal of Child and Family Studies, Apr 20, 2019

Research paper thumbnail of Positivity and Negativity in Interparental Conflict

Swiss Journal of Psychology, 2016

Research paper thumbnail of Intensive Cognitive-Behavioral Therapy for Anxiety Disorders in Adolescents: A Case Study

Clinical Case Studies, Aug 23, 2022

Anxiety disorders are one of the most common psychiatric conditions in youth and can contribute t... more Anxiety disorders are one of the most common psychiatric conditions in youth and can contribute to impairment in social, academic, and family functioning. Cognitive-behavioral therapy (CBT) has been shown to be efficacious in treating youth anxiety disorders; however, for a multitude of reasons, fewer than 20% of adolescents with anxiety disorders receive services for anxiety-related problems. Intensive treatments, which rely on the same traditional components of CBT but are delivered over a shorter period of time or in a fewer number of sessions, may be particularly helpful for anxiety disorders and can offer a number of advantages over standard CBT. Despite emerging evidence supporting the advantages of the intensive approach, there are few established intensive treatment programs for youth with anxiety disorders. Further, no treatment to date has comprehensively targeted the entire spectrum of comorbid adolescent anxiety disorders in a combined intensive and transdiagnostic format, even though non-intensive (i.e., weekly delivered) CBT has been tested using a transdiagnostic approach. We developed an intensive, six-session intervention based on Angelosante and colleagues’ 2009 The Adolescent Panic Control Treatment with In-Vivo Exposures (Angelosante et al., 2009) and other empirically-supported treatments for youth to target all anxiety disorders in adolescents. We present a case study on an adolescent with multiple comorbid anxiety and related disorders who received intensive CBT treatment as a way to illustrate the clinical benefit and utility of an intensive, transdiagnostic approach. Findings support the acceptability and feasibility of transdiagnostic treatment of youth anxiety.

Research paper thumbnail of 23.3 Empowering and Supporting Young People with Climate Distress: Clinical Applications

Journal of the American Academy of Child and Adolescent Psychiatry, Oct 1, 2022

Research paper thumbnail of Caretaking Behaviors and Stress Reactivity in Adolescents of Depressed Parents

This study was designed to explore the correlates of stress reactivity and caretaking behaviors i... more This study was designed to explore the correlates of stress reactivity and caretaking behaviors in an at-risk sample of children living with a parent who has experienced at least one episode of major depressive disorder during the lifetime of his or her child. This thesis was written to satisfy the requirements of PSY 2990: Honors Psychology Research under Craig Smith.

Research paper thumbnail of 40. Neural Correlates of Adolescent Irritability and Its Comorbidity

Biological Psychiatry, May 1, 2017

Conclusions: Brain morphology estimated from T1 weighted volume and thickness measures were not a... more Conclusions: Brain morphology estimated from T1 weighted volume and thickness measures were not able to significantly explain variation in trait irritability. This study poses questions on whether volumetric and thickness differences among subjects can help in explaining the pathophysiology of irritability in children. It also reinforces the importance of other imaging modalities as a way to advance the understanding the pathophysiology of irritability.

Research paper thumbnail of 23.3 Empowering and Supporting Young People with Climate Distress: Clinical Applications

Journal of the American Academy of Child & Adolescent Psychiatry

Research paper thumbnail of Evidence of amygdala hypersensitivity to signals of threat

Cannabis use in adolescence may be characterized by differences in the neural basis of affective ... more Cannabis use in adolescence may be characterized by differences in the neural basis of affective processing. In this study, we used an fMRI affective face processing task to compare a large group (n = 70) of 14-year olds with a history of cannabis use to a group (n = 70) of never-using controls matched on numerous characteristics including IQ, SES, alcohol and cigarette use. The task contained short movies displaying angry and neutral faces. Results indicated that cannabis users had greater reactivity in the bilateral amygdalae to angry faces than neutral faces, an effect that was not observed in their abstinent peers. In contrast, activity levels in the cannabis users in cortical areas including the right temporal-parietal junction and bilateral dorsolateral prefrontal cortex did not discriminate between the two face conditions, but did differ in controls. Results did not change after excluding subjects with any psychiatric symptomology. Given the high density of cannabinoid recept...

Research paper thumbnail of Cannabis use in early adolescence

Cannabis use in adolescence may be characterized by differences in the neural basis of affective ... more Cannabis use in adolescence may be characterized by differences in the neural basis of affective processing. In this study, we used an fMRI affective face processing task to compare a large group (n = 70) of 14-year olds with a history of cannabis use to a group (n = 70) of never-using controls matched on numerous characteristics including IQ, SES, alcohol and cigarette use. The task contained short movies displaying angry and neutral faces. Results indicated that cannabis users had greater reactivity in the bilateral amygdalae to angry faces than neutral faces, an effect that was not observed in their abstinent peers. In contrast, activity levels in the cannabis users in cortical areas including the right temporal-parietal junction and bilateral dorsolateral prefrontal cortex did not discriminate between the two face conditions, but did differ in controls. Results did not change after excluding subjects with any psychiatric symptomology. Given the high density of cannabinoid recept...

Research paper thumbnail of The Neural Basis of Response Inhibition and Substance Abuse

The Wiley Handbook of Cognitive Control, 2017

Research paper thumbnail of Caretaking Behaviors and Stress Reactivity in Adolescents of Depressed Parents

This study was designed to explore the correlates of stress reactivity and caretaking behaviors i... more This study was designed to explore the correlates of stress reactivity and caretaking behaviors in an at-risk sample of children living with a parent who has experienced at least one episode of major depressive disorder during the lifetime of his or her child. This thesis was written to satisfy the requirements of PSY 2990: Honors Psychology Research under Craig Smith.

Research paper thumbnail of Risk profiles for adolescent internalizing problems

Objective: Internalizing problems are commonly diagnosed during adolescence, and are associated w... more Objective: Internalizing problems are commonly diagnosed during adolescence, and are associated with distress, impairment, and negative mental health outcomes in adulthood. Thus, there is a critical need to characterize adolescents who are at the highest risk for escalating to clinical levels of internalizing problems while extending current literature and incorporating both biological and environmental predictors. This study aimed to characterized risk profiles for fourteen-year-old adolescents who developed clinical levels of internalizing (High Internalizing [HI]) problems by age nineteen, using brain, genetic, personality, cognitive, life history, psychopathology, and demographic measures. The study also examined whether there were functional and structural brain differences in three groups of adolescents on select regions of interest (ROIs) on the Faces Task, Stop Signal Task, and Modified Incentive Delay Task. Method: Participants were 91 adolescents who met clinical criteria ...

Research paper thumbnail of Title : Low smoking-exposure , the adolescent brain , and the modulating role of CHRNA 5 polymorphisms

CHRNA5 polymorphisms Authors: Bader Chaarani , Kees-Jan Kan , Scott Mackey , Philip A. Spechler ,... more CHRNA5 polymorphisms Authors: Bader Chaarani , Kees-Jan Kan , Scott Mackey , Philip A. Spechler , Alexandra Potter , Catherine Orr , Nicholas D’Alberto , Kelsey E. Hudson , Tobias Banaschewski , Arun L.W. Bokde , Uli Bromberg , Christian Büchel , Anna Cattrell , Patricia J.Conrod , Sylvane Desrivières , Herta Flor , Vincent Frouin , Jürgen Gallinat , Penny Gowland , Andreas Heinz , Bernd Ittermann , Jean-Luc Martinot , Frauke Nees , Dimitri Papadopoulos-Orfanos , Tomáš Paus , Luise Poustka , Michael N. Smolka , Henrik Walter , Robert Whelan , Stephen T. Higgins , Gunter Schumann , Robert R. Althoff , Elliot A. Stein , Hugh Garavan , & the IMAGEN Consortium. Affiliations: Vermont Center on Behavior and Health, Departments of Psychiatry and Psychology, University of Vermont, 05405 Burlington, Vermont, USA. Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159 Mannheim, Germ...

Research paper thumbnail of Cross-Disorder Cognitive Impairments in Youth Referred for Neuropsychiatric Evaluation

Journal of the International Neuropsychological Society : JINS, Jan 4, 2017

Studies suggest that impairments in some of the same domains of cognition occur in different neur... more Studies suggest that impairments in some of the same domains of cognition occur in different neuropsychiatric conditions, including those known to share genetic liability. Yet, direct, multi-disorder cognitive comparisons are limited, and it remains unclear whether overlapping deficits are due to comorbidity. We aimed to extend the literature by examining cognition across different neuropsychiatric conditions and addressing comorbidity. Subjects were 486 youth consecutively referred for neuropsychiatric evaluation and enrolled in the Longitudinal Study of Genetic Influences on Cognition. First, we assessed general ability, reaction time variability (RTV), and aspects of executive functions (EFs) in youth with non-comorbid forms of attention-deficit/hyperactivity disorder (ADHD), mood disorders and autism spectrum disorder (ASD), as well as in youth with psychosis. Second, we determined the impact of comorbid ADHD on cognition in youth with ASD and mood disorders. For EFs (working me...

Research paper thumbnail of Response inhibition and addiction medicine: from use to abstinence

Progress in brain research, 2016

Historically, neuroscientific research into addiction has emphasized affective and reinforcement ... more Historically, neuroscientific research into addiction has emphasized affective and reinforcement mechanisms as the essential elements underlying the pursuit of drugs, their abuse, and difficulties associated with abstinence. However, research over the last decade or so has shown that cognitive control systems, associated largely but not exclusively with the frontal lobes, are also important contributors to drug use behaviors. Here, we focus on inhibitory control and its contribution to both current use and abstinence. A body of evidence points to impaired inhibitory abilities across a range of drugs of abuse. Typically, studies suggest that substance-abusing individuals are characterized by relative hypoactivity in brain systems underlying inhibitory control. In contrast, abstinent users tend to show either normal or supernormal levels of activity in the same systems attesting to the importance of inhibitory control in suppressing the drug use urges that plague attempts at abstinenc...

Research paper thumbnail of Observed parental responsiveness/warmth and children’s coping: Cross-sectional and prospective relations in a family depression preventive intervention

Journal of Family Psychology, 2014

The current study examined concurrent and prospective relations between observed parenting behavi... more The current study examined concurrent and prospective relations between observed parenting behaviors and children's coping strategies in the context of a preventive intervention designed to change both parenting and children's use of secondary control coping. Questionnaires and direct observations were obtained from parents with a history of depression (N = 180) and their children (ages 9-15 years) at baseline, 6-month (after completion of the intervention), and 18-month follow-up assessments. Cross-sectional analyses indicate that baseline observed parental responsiveness/warmth was significantly associated with composite parent/child reports of children's baseline primary control, secondary control, and disengagement coping. Using a mixed effects model, prospective mediational analyses indicate that intervention-driven improvements in observed parental responsiveness/warmth from baseline to 6-months significantly accounted for increases in children's use of secondary control coping strategies from baseline to the 18-month follow-up assessment. No significant mediation effects emerged for primary control coping or disengagement coping. The present findings suggest that it may be possible to improve children's

Research paper thumbnail of Mental Health and Well-Being for Patients and Clinicians

Journal of Occupational & Environmental Medicine

Research paper thumbnail of The Effects of Climate Change on Child and Adolescent Mental Health: Clinical Considerations

Current Psychiatry Reports, 2021

We review recent literature on the effects of climate change on child and adolescent mental healt... more We review recent literature on the effects of climate change on child and adolescent mental health and discuss treatment and engagement by clinicians. Climate change affects child and adolescent mental health in many intersecting ways, including as a social and ecological determinant of health, a threat amplifier, and a source of trauma and distress. Single extreme weather events contribute to significant negative mental health consequences; however, subacute and chronic climate events also have mental health sequelae. Furthermore, awareness of the climate crisis is associated with emotional distress. Young people with pre-existing mental illness and lacking social support may be at elevated risk for climate change-related mental health effects. Climate activism is associated with resilience and positive development, but may also be a source of increased stress, particularly for marginalized youths. Climate change can affect the mental health of children and adolescents in complex and diverse ways. Sources of coping and resilience also vary greatly between individuals. Mental health clinicians must respond to this existential crisis by addressing research gaps in this area, obtaining relevant clinical training, educating their communities, and joining and supporting young people in their advocacy efforts.

Research paper thumbnail of Positivity and Negativity in Interparental Conflict: Links with Children’s Evaluations and Appraisals

Journal of Child and Family Studies, Apr 20, 2019

Research paper thumbnail of Positivity and Negativity in Interparental Conflict

Swiss Journal of Psychology, 2016

Research paper thumbnail of Intensive Cognitive-Behavioral Therapy for Anxiety Disorders in Adolescents: A Case Study

Clinical Case Studies, Aug 23, 2022

Anxiety disorders are one of the most common psychiatric conditions in youth and can contribute t... more Anxiety disorders are one of the most common psychiatric conditions in youth and can contribute to impairment in social, academic, and family functioning. Cognitive-behavioral therapy (CBT) has been shown to be efficacious in treating youth anxiety disorders; however, for a multitude of reasons, fewer than 20% of adolescents with anxiety disorders receive services for anxiety-related problems. Intensive treatments, which rely on the same traditional components of CBT but are delivered over a shorter period of time or in a fewer number of sessions, may be particularly helpful for anxiety disorders and can offer a number of advantages over standard CBT. Despite emerging evidence supporting the advantages of the intensive approach, there are few established intensive treatment programs for youth with anxiety disorders. Further, no treatment to date has comprehensively targeted the entire spectrum of comorbid adolescent anxiety disorders in a combined intensive and transdiagnostic format, even though non-intensive (i.e., weekly delivered) CBT has been tested using a transdiagnostic approach. We developed an intensive, six-session intervention based on Angelosante and colleagues’ 2009 The Adolescent Panic Control Treatment with In-Vivo Exposures (Angelosante et al., 2009) and other empirically-supported treatments for youth to target all anxiety disorders in adolescents. We present a case study on an adolescent with multiple comorbid anxiety and related disorders who received intensive CBT treatment as a way to illustrate the clinical benefit and utility of an intensive, transdiagnostic approach. Findings support the acceptability and feasibility of transdiagnostic treatment of youth anxiety.

Research paper thumbnail of 23.3 Empowering and Supporting Young People with Climate Distress: Clinical Applications

Journal of the American Academy of Child and Adolescent Psychiatry, Oct 1, 2022

Research paper thumbnail of Caretaking Behaviors and Stress Reactivity in Adolescents of Depressed Parents

This study was designed to explore the correlates of stress reactivity and caretaking behaviors i... more This study was designed to explore the correlates of stress reactivity and caretaking behaviors in an at-risk sample of children living with a parent who has experienced at least one episode of major depressive disorder during the lifetime of his or her child. This thesis was written to satisfy the requirements of PSY 2990: Honors Psychology Research under Craig Smith.

Research paper thumbnail of 40. Neural Correlates of Adolescent Irritability and Its Comorbidity

Biological Psychiatry, May 1, 2017

Conclusions: Brain morphology estimated from T1 weighted volume and thickness measures were not a... more Conclusions: Brain morphology estimated from T1 weighted volume and thickness measures were not able to significantly explain variation in trait irritability. This study poses questions on whether volumetric and thickness differences among subjects can help in explaining the pathophysiology of irritability in children. It also reinforces the importance of other imaging modalities as a way to advance the understanding the pathophysiology of irritability.

Research paper thumbnail of 23.3 Empowering and Supporting Young People with Climate Distress: Clinical Applications

Journal of the American Academy of Child & Adolescent Psychiatry

Research paper thumbnail of Evidence of amygdala hypersensitivity to signals of threat

Cannabis use in adolescence may be characterized by differences in the neural basis of affective ... more Cannabis use in adolescence may be characterized by differences in the neural basis of affective processing. In this study, we used an fMRI affective face processing task to compare a large group (n = 70) of 14-year olds with a history of cannabis use to a group (n = 70) of never-using controls matched on numerous characteristics including IQ, SES, alcohol and cigarette use. The task contained short movies displaying angry and neutral faces. Results indicated that cannabis users had greater reactivity in the bilateral amygdalae to angry faces than neutral faces, an effect that was not observed in their abstinent peers. In contrast, activity levels in the cannabis users in cortical areas including the right temporal-parietal junction and bilateral dorsolateral prefrontal cortex did not discriminate between the two face conditions, but did differ in controls. Results did not change after excluding subjects with any psychiatric symptomology. Given the high density of cannabinoid recept...

Research paper thumbnail of Cannabis use in early adolescence

Cannabis use in adolescence may be characterized by differences in the neural basis of affective ... more Cannabis use in adolescence may be characterized by differences in the neural basis of affective processing. In this study, we used an fMRI affective face processing task to compare a large group (n = 70) of 14-year olds with a history of cannabis use to a group (n = 70) of never-using controls matched on numerous characteristics including IQ, SES, alcohol and cigarette use. The task contained short movies displaying angry and neutral faces. Results indicated that cannabis users had greater reactivity in the bilateral amygdalae to angry faces than neutral faces, an effect that was not observed in their abstinent peers. In contrast, activity levels in the cannabis users in cortical areas including the right temporal-parietal junction and bilateral dorsolateral prefrontal cortex did not discriminate between the two face conditions, but did differ in controls. Results did not change after excluding subjects with any psychiatric symptomology. Given the high density of cannabinoid recept...

Research paper thumbnail of The Neural Basis of Response Inhibition and Substance Abuse

The Wiley Handbook of Cognitive Control, 2017

Research paper thumbnail of Caretaking Behaviors and Stress Reactivity in Adolescents of Depressed Parents

This study was designed to explore the correlates of stress reactivity and caretaking behaviors i... more This study was designed to explore the correlates of stress reactivity and caretaking behaviors in an at-risk sample of children living with a parent who has experienced at least one episode of major depressive disorder during the lifetime of his or her child. This thesis was written to satisfy the requirements of PSY 2990: Honors Psychology Research under Craig Smith.

Research paper thumbnail of Risk profiles for adolescent internalizing problems

Objective: Internalizing problems are commonly diagnosed during adolescence, and are associated w... more Objective: Internalizing problems are commonly diagnosed during adolescence, and are associated with distress, impairment, and negative mental health outcomes in adulthood. Thus, there is a critical need to characterize adolescents who are at the highest risk for escalating to clinical levels of internalizing problems while extending current literature and incorporating both biological and environmental predictors. This study aimed to characterized risk profiles for fourteen-year-old adolescents who developed clinical levels of internalizing (High Internalizing [HI]) problems by age nineteen, using brain, genetic, personality, cognitive, life history, psychopathology, and demographic measures. The study also examined whether there were functional and structural brain differences in three groups of adolescents on select regions of interest (ROIs) on the Faces Task, Stop Signal Task, and Modified Incentive Delay Task. Method: Participants were 91 adolescents who met clinical criteria ...

Research paper thumbnail of Title : Low smoking-exposure , the adolescent brain , and the modulating role of CHRNA 5 polymorphisms

CHRNA5 polymorphisms Authors: Bader Chaarani , Kees-Jan Kan , Scott Mackey , Philip A. Spechler ,... more CHRNA5 polymorphisms Authors: Bader Chaarani , Kees-Jan Kan , Scott Mackey , Philip A. Spechler , Alexandra Potter , Catherine Orr , Nicholas D’Alberto , Kelsey E. Hudson , Tobias Banaschewski , Arun L.W. Bokde , Uli Bromberg , Christian Büchel , Anna Cattrell , Patricia J.Conrod , Sylvane Desrivières , Herta Flor , Vincent Frouin , Jürgen Gallinat , Penny Gowland , Andreas Heinz , Bernd Ittermann , Jean-Luc Martinot , Frauke Nees , Dimitri Papadopoulos-Orfanos , Tomáš Paus , Luise Poustka , Michael N. Smolka , Henrik Walter , Robert Whelan , Stephen T. Higgins , Gunter Schumann , Robert R. Althoff , Elliot A. Stein , Hugh Garavan , & the IMAGEN Consortium. Affiliations: Vermont Center on Behavior and Health, Departments of Psychiatry and Psychology, University of Vermont, 05405 Burlington, Vermont, USA. Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159 Mannheim, Germ...

Research paper thumbnail of Cross-Disorder Cognitive Impairments in Youth Referred for Neuropsychiatric Evaluation

Journal of the International Neuropsychological Society : JINS, Jan 4, 2017

Studies suggest that impairments in some of the same domains of cognition occur in different neur... more Studies suggest that impairments in some of the same domains of cognition occur in different neuropsychiatric conditions, including those known to share genetic liability. Yet, direct, multi-disorder cognitive comparisons are limited, and it remains unclear whether overlapping deficits are due to comorbidity. We aimed to extend the literature by examining cognition across different neuropsychiatric conditions and addressing comorbidity. Subjects were 486 youth consecutively referred for neuropsychiatric evaluation and enrolled in the Longitudinal Study of Genetic Influences on Cognition. First, we assessed general ability, reaction time variability (RTV), and aspects of executive functions (EFs) in youth with non-comorbid forms of attention-deficit/hyperactivity disorder (ADHD), mood disorders and autism spectrum disorder (ASD), as well as in youth with psychosis. Second, we determined the impact of comorbid ADHD on cognition in youth with ASD and mood disorders. For EFs (working me...

Research paper thumbnail of Response inhibition and addiction medicine: from use to abstinence

Progress in brain research, 2016

Historically, neuroscientific research into addiction has emphasized affective and reinforcement ... more Historically, neuroscientific research into addiction has emphasized affective and reinforcement mechanisms as the essential elements underlying the pursuit of drugs, their abuse, and difficulties associated with abstinence. However, research over the last decade or so has shown that cognitive control systems, associated largely but not exclusively with the frontal lobes, are also important contributors to drug use behaviors. Here, we focus on inhibitory control and its contribution to both current use and abstinence. A body of evidence points to impaired inhibitory abilities across a range of drugs of abuse. Typically, studies suggest that substance-abusing individuals are characterized by relative hypoactivity in brain systems underlying inhibitory control. In contrast, abstinent users tend to show either normal or supernormal levels of activity in the same systems attesting to the importance of inhibitory control in suppressing the drug use urges that plague attempts at abstinenc...

Research paper thumbnail of Observed parental responsiveness/warmth and children’s coping: Cross-sectional and prospective relations in a family depression preventive intervention

Journal of Family Psychology, 2014

The current study examined concurrent and prospective relations between observed parenting behavi... more The current study examined concurrent and prospective relations between observed parenting behaviors and children's coping strategies in the context of a preventive intervention designed to change both parenting and children's use of secondary control coping. Questionnaires and direct observations were obtained from parents with a history of depression (N = 180) and their children (ages 9-15 years) at baseline, 6-month (after completion of the intervention), and 18-month follow-up assessments. Cross-sectional analyses indicate that baseline observed parental responsiveness/warmth was significantly associated with composite parent/child reports of children's baseline primary control, secondary control, and disengagement coping. Using a mixed effects model, prospective mediational analyses indicate that intervention-driven improvements in observed parental responsiveness/warmth from baseline to 6-months significantly accounted for increases in children's use of secondary control coping strategies from baseline to the 18-month follow-up assessment. No significant mediation effects emerged for primary control coping or disengagement coping. The present findings suggest that it may be possible to improve children's

Research paper thumbnail of Mental Health and Well-Being for Patients and Clinicians

Journal of Occupational & Environmental Medicine

Research paper thumbnail of The Effects of Climate Change on Child and Adolescent Mental Health: Clinical Considerations

Current Psychiatry Reports, 2021

We review recent literature on the effects of climate change on child and adolescent mental healt... more We review recent literature on the effects of climate change on child and adolescent mental health and discuss treatment and engagement by clinicians. Climate change affects child and adolescent mental health in many intersecting ways, including as a social and ecological determinant of health, a threat amplifier, and a source of trauma and distress. Single extreme weather events contribute to significant negative mental health consequences; however, subacute and chronic climate events also have mental health sequelae. Furthermore, awareness of the climate crisis is associated with emotional distress. Young people with pre-existing mental illness and lacking social support may be at elevated risk for climate change-related mental health effects. Climate activism is associated with resilience and positive development, but may also be a source of increased stress, particularly for marginalized youths. Climate change can affect the mental health of children and adolescents in complex and diverse ways. Sources of coping and resilience also vary greatly between individuals. Mental health clinicians must respond to this existential crisis by addressing research gaps in this area, obtaining relevant clinical training, educating their communities, and joining and supporting young people in their advocacy efforts.