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Papers by Kirti Prabhu

Research paper thumbnail of A HPTLC densitometric method for the determination of aloeverose in Aloe vera gel

Fitoterapia, 2010

Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcar... more Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcare and cosmetic products. As to date there are no documented reports on the standardization of A. vera gel and the following study is an attempt in this direction. A. vera gel was evaluated for its aloeverose content for the first time. Aloeverose, was separated on a thin-layer of silica gel by isocratic gradient elution technique was determined by using HPTLC-photodensitometry. The proposed method is simple and sensitive and can be used for the routine assay of aloeverose in phytomedicines containing A. vera gel.

Research paper thumbnail of Curcuma zedoaria Rosc. (white turmeric): a review of its chemical, pharmacological and ethnomedicinal properties

Journal of Pharmacy and Pharmacology, 2009

Objectives Curcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, ... more Objectives Curcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, Japan and Thailand. Various parts of this plant are used in Ayurveda and other folk medicines for the treatment of different ailments such as diarrhoea, cancer, flatulence and dyspepsia. This study is an attempt to compile an up-to-date and comprehensive review of C. zedoaria that covers its traditional and folk medicinal uses, phytochemistry and pharmacology. Key findings Research carried out using different in-vitro and in-vivo techniques of biological evaluation supports most of the claims. Summary This review presents the botany, chemistry, traditional uses and pharmacological data of the plant.

Research paper thumbnail of Antidiabetic properties of the alcoholic extract of Sphaeranthus indicus in streptozotocin-nicotinamide diabetic rats

Journal of Pharmacy and Pharmacology, 2008

We have investigated the possible antihyperglycaemic effects of Sphaeranthus indicus extract in r... more We have investigated the possible antihyperglycaemic effects of Sphaeranthus indicus extract in rats rendered diabetic by nicotinamide (120 mgkg−1 i.p.) and streptozotocin (STZ) (60 mgkg−1 i.p). Fasting plasma glucose levels, serum insulin levels, serum lipid profiles, magnesium levels, glycosylated haemoglobin, changes in body weight and liver glycogen levels were evaluated in normal and diabetic rats. Oral administration of S. indicus for 15 days resulted in significant decrease in blood glucose levels and increases in hepatic glycogen and plasma insulin levels. Fasting normal rats treated with the alcoholic extract of S. indicus showed significant improvement in oral glucose tolerance test. Glibenclamide was used as a reference standard. The findings demonstrate that the alcoholic S. indicus extract may be useful in the treatment of diabetes.

Research paper thumbnail of Curcuma zedoaria Rosc. (white turmeric): a review of its chemical, pharmacological and ethnomedicinal properties

Journal of Pharmacy and Pharmacology, 2009

ObjectivesCurcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, J... more ObjectivesCurcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, Japan and Thailand. Various parts of this plant are used in Ayurveda and other folk medicines for the treatment of different ailments such as diarrhoea, cancer, flatulence and dyspepsia. This study is an attempt to compile an up-to-date and comprehensive review of C. zedoaria that covers its traditional and folk medicinal uses, phytochemistry and pharmacology.Key findings Research carried out using different in-vitro and in-vivo techniques of biological evaluation supports most of the claims.Summary This review presents the botany, chemistry, traditional uses and pharmacological data of the plant.

Research paper thumbnail of A HPTLC densitometric method for the determination of aloeverose in Aloe vera gel

Fitoterapia, 2010

Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcar... more Aloe vera gel is a familiar ingredient in a range of widely available and advertisement healthcare and cosmetic products. As to date there are no documented reports on the standardization of A. vera gel and the following study is an attempt in this direction. A. vera gel was evaluated for its aloeverose content for the first time. Aloeverose, was separated on a thin-layer of silica gel by isocratic gradient elution technique was determined by using HPTLC-photodensitometry. The proposed method is simple and sensitive and can be used for the routine assay of aloeverose in phytomedicines containing A. vera gel.

Research paper thumbnail of Curcuma zedoaria Rosc. (white turmeric): a review of its chemical, pharmacological and ethnomedicinal properties

Journal of Pharmacy and Pharmacology, 2009

Objectives Curcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, ... more Objectives Curcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, Japan and Thailand. Various parts of this plant are used in Ayurveda and other folk medicines for the treatment of different ailments such as diarrhoea, cancer, flatulence and dyspepsia. This study is an attempt to compile an up-to-date and comprehensive review of C. zedoaria that covers its traditional and folk medicinal uses, phytochemistry and pharmacology. Key findings Research carried out using different in-vitro and in-vivo techniques of biological evaluation supports most of the claims. Summary This review presents the botany, chemistry, traditional uses and pharmacological data of the plant.

Research paper thumbnail of Antidiabetic properties of the alcoholic extract of Sphaeranthus indicus in streptozotocin-nicotinamide diabetic rats

Journal of Pharmacy and Pharmacology, 2008

We have investigated the possible antihyperglycaemic effects of Sphaeranthus indicus extract in r... more We have investigated the possible antihyperglycaemic effects of Sphaeranthus indicus extract in rats rendered diabetic by nicotinamide (120 mgkg−1 i.p.) and streptozotocin (STZ) (60 mgkg−1 i.p). Fasting plasma glucose levels, serum insulin levels, serum lipid profiles, magnesium levels, glycosylated haemoglobin, changes in body weight and liver glycogen levels were evaluated in normal and diabetic rats. Oral administration of S. indicus for 15 days resulted in significant decrease in blood glucose levels and increases in hepatic glycogen and plasma insulin levels. Fasting normal rats treated with the alcoholic extract of S. indicus showed significant improvement in oral glucose tolerance test. Glibenclamide was used as a reference standard. The findings demonstrate that the alcoholic S. indicus extract may be useful in the treatment of diabetes.

Research paper thumbnail of Curcuma zedoaria Rosc. (white turmeric): a review of its chemical, pharmacological and ethnomedicinal properties

Journal of Pharmacy and Pharmacology, 2009

ObjectivesCurcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, J... more ObjectivesCurcuma zedoaria Rosc is a perennial herb found in tropical countries, such as India, Japan and Thailand. Various parts of this plant are used in Ayurveda and other folk medicines for the treatment of different ailments such as diarrhoea, cancer, flatulence and dyspepsia. This study is an attempt to compile an up-to-date and comprehensive review of C. zedoaria that covers its traditional and folk medicinal uses, phytochemistry and pharmacology.Key findings Research carried out using different in-vitro and in-vivo techniques of biological evaluation supports most of the claims.Summary This review presents the botany, chemistry, traditional uses and pharmacological data of the plant.

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