Klaus Bergander - Academia.edu (original) (raw)
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Papers by Klaus Bergander
ELECTROPHORESIS, 2002
Twenty-three cationic chiral analytes were resolved in capillary electrophoresis using native b-c... more Twenty-three cationic chiral analytes were resolved in capillary electrophoresis using native b-cyclodextrin and single isomer heptakis-(2-O-methyl-3,6-di-O-sulfo)-b-cyclodextrin as chiral selectors. For 12 of 16 chiral analytes resolved with both chiral selectors the enantiomer migration order was opposite. In selected cases the structure of cyclodextrin-analyte complexes in aqueous solution was investigated using onedimensional transverse rotating frame nuclear Overhauser and exchange spectroscopy. It was found that in contrast to mainly inclusion-type complexes between chiral analytes and b-cyclodextrin, external complexes are formed between the chiral analytes and structurally crowded, highly charged heptakis-(2-O-methyl-3,6-di-O-sulfo)b-cyclodextrin.
ELECTROPHORESIS, 2002
Twenty-three cationic chiral analytes were resolved in capillary electrophoresis using native b-c... more Twenty-three cationic chiral analytes were resolved in capillary electrophoresis using native b-cyclodextrin and single isomer heptakis-(2-O-methyl-3,6-di-O-sulfo)-b-cyclodextrin as chiral selectors. For 12 of 16 chiral analytes resolved with both chiral selectors the enantiomer migration order was opposite. In selected cases the structure of cyclodextrin-analyte complexes in aqueous solution was investigated using onedimensional transverse rotating frame nuclear Overhauser and exchange spectroscopy. It was found that in contrast to mainly inclusion-type complexes between chiral analytes and b-cyclodextrin, external complexes are formed between the chiral analytes and structurally crowded, highly charged heptakis-(2-O-methyl-3,6-di-O-sulfo)b-cyclodextrin.