Knc Murthy - Academia.edu (original) (raw)

Papers by Knc Murthy

International Journal of Food Sciences and Nutrition, 2007

The composition of polar, neutral and glycolipid fractions of two halotolerant algae, Dunaliella ... more The composition of polar, neutral and glycolipid fractions of two halotolerant algae, Dunaliella salina and Dunaliella bardawil, which are exclusively used for the production of beta-carotene was determined in modified medium. In D. salina the glycolipid fraction accounted to 28%, in comparison with 40% of D. bardawil. However, in D. salina the polar lipid was 42% compared with D. bardawil at 24%. The glycolipid fraction of D. bardawil was rich in linolenic acid (81%). In both the species we could find elongation in the fatty acids from C(16) to C(20) to C(22) and the percentage was higher than the earlier reports (>3%). The polar lipid fraction was composed of (in descending order) phosphatidyl glycerol, phosphatidic acid, phosphatidic ethanolamine, phosphatidyl choline and phosphatidyl glycerol and the neutral lipid fraction, which was rich in monoglycerides and diglycerides and diacylglycero-trimethylhomoserine.

Journal of Agricultural and Food Chemistry, 2006

The present study reports the antioxidant activity of flaxseed as measured by feeding weanling al... more The present study reports the antioxidant activity of flaxseed as measured by feeding weanling albino rats with 5.0% and 10.0% of flaxseed (constituting approximately 0.75 and 1.5 g kg-1) for 14 days followed by challenging animals with 2.0 g kg-1 b.w. CCl 4 as toxin. Activity was assessed by measuring hepatic marker enzymes like catalase, superoxide dismutase (SOD), and peroxidase and comparing with those from the normal group and from a group receiving toxin without flaxseed. Treatment of CCl 4 at dose of 2.0 g kg-1 b.w. decreased the activities of various antioxidant enzymes such as catalase, superoxide dismutase (SOD), and peroxidase by 35.6%, 47.76%, and 53.0%, respectively, compared to the control group, and the lipid peroxidation value increased nearly 1.2-fold compared to that of the group treated with toxin without flaxseed. Pretreatment of rats with 5.0% flaxseed followed by CCl 4 treatment caused restoration of catalase, SOD, and peroxidase by 39.7%, 181.42%, and 123.7%, respectively, as compared to control. The group treated with 10.0% flaxseed has shown the restoration of 95.02%, 182.31%, and 136.0% of catalase, SOD, and peroxidase. In the case of the group treated with toxin without flaxseed, the level of superoxide dismutase and the catalse value decreased 91.4% and 55.33%, respectively, in comparison with the control group. These results clearly indicate the beneficial effect of flaxseed components as an antioxidant as seen by restoration of hepatic enzymes, which were varied from normal to one due to toxicity induced by toxin (CCl 4). Owing to this property, the flaxseed known for its functional properties can be further extended to exploit its possible application for various health benefits as nutraceuticals and food ingredient.

International Journal of Food Sciences and Nutrition, 2007

The composition of polar, neutral and glycolipid fractions of two halotolerant algae, Dunaliella ... more The composition of polar, neutral and glycolipid fractions of two halotolerant algae, Dunaliella salina and Dunaliella bardawil, which are exclusively used for the production of beta-carotene was determined in modified medium. In D. salina the glycolipid fraction accounted to 28%, in comparison with 40% of D. bardawil. However, in D. salina the polar lipid was 42% compared with D. bardawil at 24%. The glycolipid fraction of D. bardawil was rich in linolenic acid (81%). In both the species we could find elongation in the fatty acids from C(16) to C(20) to C(22) and the percentage was higher than the earlier reports (>3%). The polar lipid fraction was composed of (in descending order) phosphatidyl glycerol, phosphatidic acid, phosphatidic ethanolamine, phosphatidyl choline and phosphatidyl glycerol and the neutral lipid fraction, which was rich in monoglycerides and diglycerides and diacylglycero-trimethylhomoserine.

Journal of Agricultural and Food Chemistry, 2006

The present study reports the antioxidant activity of flaxseed as measured by feeding weanling al... more The present study reports the antioxidant activity of flaxseed as measured by feeding weanling albino rats with 5.0% and 10.0% of flaxseed (constituting approximately 0.75 and 1.5 g kg-1) for 14 days followed by challenging animals with 2.0 g kg-1 b.w. CCl 4 as toxin. Activity was assessed by measuring hepatic marker enzymes like catalase, superoxide dismutase (SOD), and peroxidase and comparing with those from the normal group and from a group receiving toxin without flaxseed. Treatment of CCl 4 at dose of 2.0 g kg-1 b.w. decreased the activities of various antioxidant enzymes such as catalase, superoxide dismutase (SOD), and peroxidase by 35.6%, 47.76%, and 53.0%, respectively, compared to the control group, and the lipid peroxidation value increased nearly 1.2-fold compared to that of the group treated with toxin without flaxseed. Pretreatment of rats with 5.0% flaxseed followed by CCl 4 treatment caused restoration of catalase, SOD, and peroxidase by 39.7%, 181.42%, and 123.7%, respectively, as compared to control. The group treated with 10.0% flaxseed has shown the restoration of 95.02%, 182.31%, and 136.0% of catalase, SOD, and peroxidase. In the case of the group treated with toxin without flaxseed, the level of superoxide dismutase and the catalse value decreased 91.4% and 55.33%, respectively, in comparison with the control group. These results clearly indicate the beneficial effect of flaxseed components as an antioxidant as seen by restoration of hepatic enzymes, which were varied from normal to one due to toxicity induced by toxin (CCl 4). Owing to this property, the flaxseed known for its functional properties can be further extended to exploit its possible application for various health benefits as nutraceuticals and food ingredient.