B Ramesh Kumar - Academia.edu (original) (raw)
Papers by B Ramesh Kumar
Journal of Pharmaceutical Analysis, 2017
Diets containing high proportions of fruits and vegetables reduce the risk of onset of chronic di... more Diets containing high proportions of fruits and vegetables reduce the risk of onset of chronic diseases. The role of herbal medicines in improving human health is gaining popularity over the years, which also increases the need for safety and efficiency of these products. Green leafy vegetables (GLVs) are the richest source of phenolic compounds with excellent antioxidant properties. Increased consumption of diets containing phenolic compounds may give positive and better results to human health and significantly improves the immune system. Highly selective, susceptible and versatile analytical techniques are necessary for extraction, identification, and quantification of phenolic compounds from plant extracts, which helps to utilize their important biological properties. Recent advances in the pre-treatment procedures, separation techniques and spectrometry methods are used for qualitative and quantitative analysis of phenolic compounds. The online coupling of liquid chromatography with mass spectrometry (LC-MS) has become a useful tool in the metabolic profiling of plant samples. In this review, the separation and identification of phenolic acids and flavonoids from GLVs by LC-MS have been discussed along with the general extraction procedures and other sources of mass spectrometer used. The review is devoted to the understanding of the structural configuration, nature and accumulation pattern of phenolic acids and flavonoids in plants and to highlighting the recent developments in the chemical investigation of these compounds by chromatographic and spectroscopic techniques. It concludes with the advantages of the combination of these two methods and prospects.
Renewable and Sustainable Energy Reviews, 2021
Abstract Algae have long been investigated as a plausible reserve of several biofuel and bioactiv... more Abstract Algae have long been investigated as a plausible reserve of several biofuel and bioactive compounds attributed to their fast-growing characteristics, shorter doubling time, and capability of accumulating lipids. Compounds extracted from algae are being studied in various sectors namely, pharmaceutical, cosmetics, cancer biology, nanoscience, food industry, etc. In view of the rich potentials of algae, this present review is aimed to highlight the significance of different cultivation aspects of microalgae like open pond and photobioreactor and advantages and disadvantages thereof. This state-of-the-art review provides the limitations of energy (biodiesel, bioethanol, biohydrogen, biomethane) products obtained from the algae in a perspective of shifting lab-scale into a field scale. In addition to the cultivation systems and biofuels, several non-energy products or value-added products obtained from algae were critically compared and presented. Data from plethora literatures discussing the advanced methods for the extraction of omega-3, omega-6 fatty acids, vitamins and nanoparticles from algae have been discussed extensively. Further, bioactive compounds extracted from several algal strains were listed. Considering the health benefits, anti-angiogenic, and anti–cancer properties of algal bioactive compounds were described along with other industrial applications. Overall, this comprehensive review will help in understanding status of algal biofuel, cultivation systems, metabolites and their application for the betterment of the human society.
Biocatalysis and Agricultural Biotechnology, 2019
Microalgae are rich source of poly unsaturated fatty acids and therefore, extraction and purifica... more Microalgae are rich source of poly unsaturated fatty acids and therefore, extraction and purification of poly unsaturated fatty acids from algal strains are emerging steeply to nourish the nutritional needs of the population. Recently, various cost-effective and efficient approaches are being explored to increase the poly unsaturated fatty acids yield in algae. In this juncture, this article attempted to connect extraction of lipid using different methods, and accumulation of lipid under various stress conditions, and accumulation of poly unsaturated fatty acids under various stress conditions. Initially, extraction of lipid from various algal strains using different techniques was discussed in detail. Then, accumulation of lipid in microalgae under the influence of various stimuli has been critically flagged, in order to enable researchers to choose an optimal lipid induction condition for food and fuel production. Later, impact of various factors or culture condition on the poly unsaturated fatty acids accumulation in algae has been extensively assessed and presented in the perspective of increasing its production for food supplement. Finally, recent literature pertaining to the lipid and poly unsaturated fatty acids production in microalgae is reviewed, and summarized.
Journal of Cleaner Production, 2021
Abstract The rapid increase of the usage of plastic products in the modern era and lack of adequa... more Abstract The rapid increase of the usage of plastic products in the modern era and lack of adequate waste management policies has led to their accumulation in the rivers beds and oceans posing severe threat to wildlife and human food chain. Bay of Bengal is the largest marine ecosystem with rich fauna of marine inhabitants and is hugely exploited by the plastic litter draining through the rivers Ganga-Brahmaputra-Meghna flowing through both India and Bangladesh. The question to be answered in this region is how to tackle the issue of marine plastic pollution with the aid of apt scientific findings and policy frameworks. Possible answers to these questions are being attempted in the present work by reviewing and evaluating the existing knowledge in science and law in both the countries to curb the menace of plastic in the Gangetic Bay of Bengal region. The review critically analyses the ill-effects of plastics on marine organisms globally and individuals residing on the coastal areas adjoining Bay of Bengal region. Further, the study finds that implementation of stringent laws and strengthening legal measures, in-depth understanding of the marine litter (plastics), robust waste management strategies, and spontaneous public involvement are mandatory to minimize the adverse effects of land-based plastics in this region of both the countries. The study hints out at a number of probable opportunities for the policy makers, environmentalists and marine biologists to work on for solving the plastic litter problem by adopting a holistic approach. The review finally concludes with the extensive research efforts needs to be carried out by an interdisciplinary approach and implications towards consumer driven changes which can create a safer environment for human race and marine organisms to survive.
Journal of Pharmaceutical Analysis, 2017
Diets containing high proportions of fruits and vegetables reduce the risk of onset of chronic di... more Diets containing high proportions of fruits and vegetables reduce the risk of onset of chronic diseases. The role of herbal medicines in improving human health is gaining popularity over the years, which also increases the need for safety and efficiency of these products. Green leafy vegetables (GLVs) are the richest source of phenolic compounds with excellent antioxidant properties. Increased consumption of diets containing phenolic compounds may give positive and better results to human health and significantly improves the immune system. Highly selective, susceptible and versatile analytical techniques are necessary for extraction, identification, and quantification of phenolic compounds from plant extracts, which helps to utilize their important biological properties. Recent advances in the pre-treatment procedures, separation techniques and spectrometry methods are used for qualitative and quantitative analysis of phenolic compounds. The online coupling of liquid chromatography with mass spectrometry (LC-MS) has become a useful tool in the metabolic profiling of plant samples. In this review, the separation and identification of phenolic acids and flavonoids from GLVs by LC-MS have been discussed along with the general extraction procedures and other sources of mass spectrometer used. The review is devoted to the understanding of the structural configuration, nature and accumulation pattern of phenolic acids and flavonoids in plants and to highlighting the recent developments in the chemical investigation of these compounds by chromatographic and spectroscopic techniques. It concludes with the advantages of the combination of these two methods and prospects.
Renewable and Sustainable Energy Reviews, 2021
Abstract Algae have long been investigated as a plausible reserve of several biofuel and bioactiv... more Abstract Algae have long been investigated as a plausible reserve of several biofuel and bioactive compounds attributed to their fast-growing characteristics, shorter doubling time, and capability of accumulating lipids. Compounds extracted from algae are being studied in various sectors namely, pharmaceutical, cosmetics, cancer biology, nanoscience, food industry, etc. In view of the rich potentials of algae, this present review is aimed to highlight the significance of different cultivation aspects of microalgae like open pond and photobioreactor and advantages and disadvantages thereof. This state-of-the-art review provides the limitations of energy (biodiesel, bioethanol, biohydrogen, biomethane) products obtained from the algae in a perspective of shifting lab-scale into a field scale. In addition to the cultivation systems and biofuels, several non-energy products or value-added products obtained from algae were critically compared and presented. Data from plethora literatures discussing the advanced methods for the extraction of omega-3, omega-6 fatty acids, vitamins and nanoparticles from algae have been discussed extensively. Further, bioactive compounds extracted from several algal strains were listed. Considering the health benefits, anti-angiogenic, and anti–cancer properties of algal bioactive compounds were described along with other industrial applications. Overall, this comprehensive review will help in understanding status of algal biofuel, cultivation systems, metabolites and their application for the betterment of the human society.
Biocatalysis and Agricultural Biotechnology, 2019
Microalgae are rich source of poly unsaturated fatty acids and therefore, extraction and purifica... more Microalgae are rich source of poly unsaturated fatty acids and therefore, extraction and purification of poly unsaturated fatty acids from algal strains are emerging steeply to nourish the nutritional needs of the population. Recently, various cost-effective and efficient approaches are being explored to increase the poly unsaturated fatty acids yield in algae. In this juncture, this article attempted to connect extraction of lipid using different methods, and accumulation of lipid under various stress conditions, and accumulation of poly unsaturated fatty acids under various stress conditions. Initially, extraction of lipid from various algal strains using different techniques was discussed in detail. Then, accumulation of lipid in microalgae under the influence of various stimuli has been critically flagged, in order to enable researchers to choose an optimal lipid induction condition for food and fuel production. Later, impact of various factors or culture condition on the poly unsaturated fatty acids accumulation in algae has been extensively assessed and presented in the perspective of increasing its production for food supplement. Finally, recent literature pertaining to the lipid and poly unsaturated fatty acids production in microalgae is reviewed, and summarized.
Journal of Cleaner Production, 2021
Abstract The rapid increase of the usage of plastic products in the modern era and lack of adequa... more Abstract The rapid increase of the usage of plastic products in the modern era and lack of adequate waste management policies has led to their accumulation in the rivers beds and oceans posing severe threat to wildlife and human food chain. Bay of Bengal is the largest marine ecosystem with rich fauna of marine inhabitants and is hugely exploited by the plastic litter draining through the rivers Ganga-Brahmaputra-Meghna flowing through both India and Bangladesh. The question to be answered in this region is how to tackle the issue of marine plastic pollution with the aid of apt scientific findings and policy frameworks. Possible answers to these questions are being attempted in the present work by reviewing and evaluating the existing knowledge in science and law in both the countries to curb the menace of plastic in the Gangetic Bay of Bengal region. The review critically analyses the ill-effects of plastics on marine organisms globally and individuals residing on the coastal areas adjoining Bay of Bengal region. Further, the study finds that implementation of stringent laws and strengthening legal measures, in-depth understanding of the marine litter (plastics), robust waste management strategies, and spontaneous public involvement are mandatory to minimize the adverse effects of land-based plastics in this region of both the countries. The study hints out at a number of probable opportunities for the policy makers, environmentalists and marine biologists to work on for solving the plastic litter problem by adopting a holistic approach. The review finally concludes with the extensive research efforts needs to be carried out by an interdisciplinary approach and implications towards consumer driven changes which can create a safer environment for human race and marine organisms to survive.