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Papers by Kun Wang
Frontiers in plant science, 2013
Rice is one of the most important model crop plants whose heterosis has been well-exploited in co... more Rice is one of the most important model crop plants whose heterosis has been well-exploited in commercial hybrid seed production via a variety of types of male-sterile lines. Hybrid rice cultivation area is steadily expanding around the world, especially in Southern Asia. Characterization of genes and proteins related to male sterility aims to understand how and why the male sterility occurs, and which proteins are the key players for microspores abortion. Recently, a series of genes and proteins related to cytoplasmic male sterility (CMS), photoperiod-sensitive male sterility, self-incompatibility, and other types of microspores deterioration have been characterized through genetics or proteomics. Especially the latter, offers us a powerful and high throughput approach to discern the novel proteins involving in male-sterile pathways which may help us to breed artificial male-sterile system. This represents an alternative tool to meet the critical challenge of further development of...
Journal of Genetics and Genomics, 2012
Zebrafish is a powerful model for the investigation of hematopoiesis. In order to isolate novel m... more Zebrafish is a powerful model for the investigation of hematopoiesis. In order to isolate novel mutants with hematopoietic defects, large-scale mutagenesis screening of zebrafish was performed. By scoring specific hematopoietic markers, 52 mutants were identified and then classified into four types based on specific phenotypic traits. Each mutant represented a putative mutation of a gene regulating the relevant aspect of hematopoiesis, including early macrophage development, early granulopoiesis, embryonic myelopoiesis, and definitive erythropoiesis/lymphopoiesis. Our method should be applicable for other types of genetic screening in zebrafish. In addition, further study of the mutants we identified may help to unveil the molecular basis of hematopoiesis.
Information Computing and Automation, 2008
2008 IEEE Conference on Cybernetics and Intelligent Systems, 2008
the spanning tree-based Genetic Algorithm (ST-GA) is an effective method to solve the multi-objec... more the spanning tree-based Genetic Algorithm (ST-GA) is an effective method to solve the multi-objective transportation optimization problem. The performance of this algorithm is definitely superior to the typical matrix-based GA. A new fuzzy-GA is proposed in this paper. At first, it adopts the Pareto method, so that the problem that the non-convex solutions are difficult to be found through common aggregation function method could be avoided; Moreover, the theory of fuzzy rules which can easily express explicit knowledge is introduced and merged in the ST-GA. Better Pareto front and Pareto optimal solutions are found in applications. Therefore, it displays that the new algorithm not only has better practicability but also has stronger intelligence. From the example, It can be found that the new algorithm is better then the ST-GA in performance.
Frontiers in plant science, 2013
Rice is one of the most important model crop plants whose heterosis has been well-exploited in co... more Rice is one of the most important model crop plants whose heterosis has been well-exploited in commercial hybrid seed production via a variety of types of male-sterile lines. Hybrid rice cultivation area is steadily expanding around the world, especially in Southern Asia. Characterization of genes and proteins related to male sterility aims to understand how and why the male sterility occurs, and which proteins are the key players for microspores abortion. Recently, a series of genes and proteins related to cytoplasmic male sterility (CMS), photoperiod-sensitive male sterility, self-incompatibility, and other types of microspores deterioration have been characterized through genetics or proteomics. Especially the latter, offers us a powerful and high throughput approach to discern the novel proteins involving in male-sterile pathways which may help us to breed artificial male-sterile system. This represents an alternative tool to meet the critical challenge of further development of...
Journal of Genetics and Genomics, 2012
Zebrafish is a powerful model for the investigation of hematopoiesis. In order to isolate novel m... more Zebrafish is a powerful model for the investigation of hematopoiesis. In order to isolate novel mutants with hematopoietic defects, large-scale mutagenesis screening of zebrafish was performed. By scoring specific hematopoietic markers, 52 mutants were identified and then classified into four types based on specific phenotypic traits. Each mutant represented a putative mutation of a gene regulating the relevant aspect of hematopoiesis, including early macrophage development, early granulopoiesis, embryonic myelopoiesis, and definitive erythropoiesis/lymphopoiesis. Our method should be applicable for other types of genetic screening in zebrafish. In addition, further study of the mutants we identified may help to unveil the molecular basis of hematopoiesis.
Information Computing and Automation, 2008
2008 IEEE Conference on Cybernetics and Intelligent Systems, 2008
the spanning tree-based Genetic Algorithm (ST-GA) is an effective method to solve the multi-objec... more the spanning tree-based Genetic Algorithm (ST-GA) is an effective method to solve the multi-objective transportation optimization problem. The performance of this algorithm is definitely superior to the typical matrix-based GA. A new fuzzy-GA is proposed in this paper. At first, it adopts the Pareto method, so that the problem that the non-convex solutions are difficult to be found through common aggregation function method could be avoided; Moreover, the theory of fuzzy rules which can easily express explicit knowledge is introduced and merged in the ST-GA. Better Pareto front and Pareto optimal solutions are found in applications. Therefore, it displays that the new algorithm not only has better practicability but also has stronger intelligence. From the example, It can be found that the new algorithm is better then the ST-GA in performance.