Lívia Fagundes - Academia.edu (original) (raw)
Papers by Lívia Fagundes
Applied Cancer …, 2006
... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Ra... more ... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Radiat Oncol Biol Phys 1995;32:317-23. 11 Valicenti RK, Gomella LG, Ismail M et al. ... J Urol 2000;163:845-50. 16 Liauw SL, Webster WS, Pistenmaa DA, Roehrborn CG. ...
Brazilian Journal of Oncology, 2018
Over the past decade, significant progress has been achieved for clinical management of lung canc... more Over the past decade, significant progress has been achieved for clinical management of lung cancers, including screening strategies, use of immunotherapy-based approaches to treat locally advanced and metastatic disease, and development of novel targeted agents for molecularly defined subgroups. In this review, we summarize the studies published/presented in 2018 that form the basis for new standard-of-care management options for lung cancers. These practice-changing studies exemplify the importance of multidisciplinary, evidence-based care to improve outcomes for lung cancer patients.
Radiation oncology (London, England), Jan 22, 2007
To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted ... more To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted to radical prostatectomy (RP) who have achieved complete PSA response and who have never been treated with hormonal therapy (HT).To present the results of biochemical control, a period free from hormonal therapy and factors related to its prognosis. from August 2002 to December 2004, 43 prostate cancer patients submitted to RP presented biochemical failure after achieving a PSA < 0.2 ng/ml. They have never received HT and were submitted to salvage 3DC-EBRT. Median age was 62 years, median preoperative PSA was 8.8 ng/ml, median Gleason Score was 7. Any PSA rise above 0.2 was defined as biochemical failure after surgery. Median 3DC-EBRT dose was 70 Gy, biochemical failure after EBRT was defined as 3 consecutive rises in PSA or a single rise enough to trigger HT. 3-year biochemical non-evidence of disease (BNED) was 71%. PSA doubling time lower than 4 months (p = 0.01) and time from recu...
International Journal of Radiation Oncology*Biology*Physics, 2007
analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification a... more analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification and results were correlated with clinically assessed radiation response. Results: PCA of spectra of 2 nd-fraction-of-radiotherapy tissues gave three clusters corresponding to complete response (CR), partial response (PR) and no response (NR), (Figure 1a). In this analysis we could discriminate no response and partial response conditions but there exists an overlap between complete and partial response conditions. We are also pursued predictive studies using tissues collected after 5 th fraction of EBRT in order to explore better discrimination between PR and CR conditions. The available results so for show good correlation with clinical response (Figure 1b). Conclusions: The findings of the study thus suggest the feasibility of Raman spectroscopic prediction of tumor response to radiotherapy.
Revista Brasileira de Oncologia Clínica, 2018
Over the past decade, significant progress has been achieved for clinical management of lung canc... more Over the past decade, significant progress has been achieved for clinical management of lung cancers, including screening strategies, use of immunotherapy-based approaches to treat locally advanced and metastatic disease, and development of novel targeted agents for molecularly defined subgroups. In this review, we summarize the studies published/presented in 2018 that form the basis for new standard-of-care management options for lung cancers. These practice-changing studies exemplify the importance of multidisciplinary, evidence-based care to improve outcomes for lung cancer patients.
Radiation oncology (London, England), 2007
To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted ... more To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted to radical prostatectomy (RP) who have achieved complete PSA response and who have never been treated with hormonal therapy (HT).To present the results of biochemical control, a period free from hormonal therapy and factors related to its prognosis. from August 2002 to December 2004, 43 prostate cancer patients submitted to RP presented biochemical failure after achieving a PSA < 0.2 ng/ml. They have never received HT and were submitted to salvage 3DC-EBRT. Median age was 62 years, median preoperative PSA was 8.8 ng/ml, median Gleason Score was 7. Any PSA rise above 0.2 was defined as biochemical failure after surgery. Median 3DC-EBRT dose was 70 Gy, biochemical failure after EBRT was defined as 3 consecutive rises in PSA or a single rise enough to trigger HT. 3-year biochemical non-evidence of disease (BNED) was 71%. PSA doubling time lower than 4 months (p = 0.01) and time from recu...
Ultrasound in Obstetrics and Gynecology, 2004
Objective The purpose of this study was to assess the accuracy of prenatal ultrasound measurement... more Objective The purpose of this study was to assess the accuracy of prenatal ultrasound measurement of anteroposterior renal pelvis diameter (APD) to discriminate between significant uropathy and idiopathic renal pelvis dilatation.
Pediatric Radiology, 2004
vention, the calculated AUC was 0.976 (95% CI=0.940-0.993). A cutoff of 15 mm showed the best dia... more vention, the calculated AUC was 0.976 (95% CI=0.940-0.993). A cutoff of 15 mm showed the best diagnostic performance for identifying the renal units requiring pyeloplasty (sensitivity, 100%; specificity, 92.5%). Conclusion: Our results suggest that postnatal APD is an excellent test for identifying fetuses with significant uropathy, as well as those requiring postnatal intervention.
Applied Cancer …, 2006
... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Ra... more ... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Radiat Oncol Biol Phys 1995;32:317-23. 11 Valicenti RK, Gomella LG, Ismail M et al. ... J Urol 2000;163:845-50. 16 Liauw SL, Webster WS, Pistenmaa DA, Roehrborn CG. ...
International Journal of Radiation Oncology*Biology*Physics, 2007
analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification a... more analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification and results were correlated with clinically assessed radiation response. Results: PCA of spectra of 2 nd -fraction-of-radiotherapy tissues gave three clusters corresponding to complete response (CR), partial response (PR) and no response (NR), ). In this analysis we could discriminate no response and partial response conditions but there exists an overlap between complete and partial response conditions. We are also pursued predictive studies using tissues collected after 5 th fraction of EBRT in order to explore better discrimination between PR and CR conditions. The available results so for show good correlation with clinical response . Conclusions: The findings of the study thus suggest the feasibility of Raman spectroscopic prediction of tumor response to radiotherapy.
Applied Cancer …, 2006
... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Ra... more ... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Radiat Oncol Biol Phys 1995;32:317-23. 11 Valicenti RK, Gomella LG, Ismail M et al. ... J Urol 2000;163:845-50. 16 Liauw SL, Webster WS, Pistenmaa DA, Roehrborn CG. ...
Brazilian Journal of Oncology, 2018
Over the past decade, significant progress has been achieved for clinical management of lung canc... more Over the past decade, significant progress has been achieved for clinical management of lung cancers, including screening strategies, use of immunotherapy-based approaches to treat locally advanced and metastatic disease, and development of novel targeted agents for molecularly defined subgroups. In this review, we summarize the studies published/presented in 2018 that form the basis for new standard-of-care management options for lung cancers. These practice-changing studies exemplify the importance of multidisciplinary, evidence-based care to improve outcomes for lung cancer patients.
Radiation oncology (London, England), Jan 22, 2007
To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted ... more To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted to radical prostatectomy (RP) who have achieved complete PSA response and who have never been treated with hormonal therapy (HT).To present the results of biochemical control, a period free from hormonal therapy and factors related to its prognosis. from August 2002 to December 2004, 43 prostate cancer patients submitted to RP presented biochemical failure after achieving a PSA < 0.2 ng/ml. They have never received HT and were submitted to salvage 3DC-EBRT. Median age was 62 years, median preoperative PSA was 8.8 ng/ml, median Gleason Score was 7. Any PSA rise above 0.2 was defined as biochemical failure after surgery. Median 3DC-EBRT dose was 70 Gy, biochemical failure after EBRT was defined as 3 consecutive rises in PSA or a single rise enough to trigger HT. 3-year biochemical non-evidence of disease (BNED) was 71%. PSA doubling time lower than 4 months (p = 0.01) and time from recu...
International Journal of Radiation Oncology*Biology*Physics, 2007
analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification a... more analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification and results were correlated with clinically assessed radiation response. Results: PCA of spectra of 2 nd-fraction-of-radiotherapy tissues gave three clusters corresponding to complete response (CR), partial response (PR) and no response (NR), (Figure 1a). In this analysis we could discriminate no response and partial response conditions but there exists an overlap between complete and partial response conditions. We are also pursued predictive studies using tissues collected after 5 th fraction of EBRT in order to explore better discrimination between PR and CR conditions. The available results so for show good correlation with clinical response (Figure 1b). Conclusions: The findings of the study thus suggest the feasibility of Raman spectroscopic prediction of tumor response to radiotherapy.
Revista Brasileira de Oncologia Clínica, 2018
Over the past decade, significant progress has been achieved for clinical management of lung canc... more Over the past decade, significant progress has been achieved for clinical management of lung cancers, including screening strategies, use of immunotherapy-based approaches to treat locally advanced and metastatic disease, and development of novel targeted agents for molecularly defined subgroups. In this review, we summarize the studies published/presented in 2018 that form the basis for new standard-of-care management options for lung cancers. These practice-changing studies exemplify the importance of multidisciplinary, evidence-based care to improve outcomes for lung cancer patients.
Radiation oncology (London, England), 2007
To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted ... more To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted to radical prostatectomy (RP) who have achieved complete PSA response and who have never been treated with hormonal therapy (HT).To present the results of biochemical control, a period free from hormonal therapy and factors related to its prognosis. from August 2002 to December 2004, 43 prostate cancer patients submitted to RP presented biochemical failure after achieving a PSA < 0.2 ng/ml. They have never received HT and were submitted to salvage 3DC-EBRT. Median age was 62 years, median preoperative PSA was 8.8 ng/ml, median Gleason Score was 7. Any PSA rise above 0.2 was defined as biochemical failure after surgery. Median 3DC-EBRT dose was 70 Gy, biochemical failure after EBRT was defined as 3 consecutive rises in PSA or a single rise enough to trigger HT. 3-year biochemical non-evidence of disease (BNED) was 71%. PSA doubling time lower than 4 months (p = 0.01) and time from recu...
Ultrasound in Obstetrics and Gynecology, 2004
Objective The purpose of this study was to assess the accuracy of prenatal ultrasound measurement... more Objective The purpose of this study was to assess the accuracy of prenatal ultrasound measurement of anteroposterior renal pelvis diameter (APD) to discriminate between significant uropathy and idiopathic renal pelvis dilatation.
Pediatric Radiology, 2004
vention, the calculated AUC was 0.976 (95% CI=0.940-0.993). A cutoff of 15 mm showed the best dia... more vention, the calculated AUC was 0.976 (95% CI=0.940-0.993). A cutoff of 15 mm showed the best diagnostic performance for identifying the renal units requiring pyeloplasty (sensitivity, 100%; specificity, 92.5%). Conclusion: Our results suggest that postnatal APD is an excellent test for identifying fetuses with significant uropathy, as well as those requiring postnatal intervention.
Applied Cancer …, 2006
... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Ra... more ... Maria Aparecida Conte Maia,2 Maria Letícia Gobo Silva,2 Ricardo César Fogaroli,2 ... Int J Radiat Oncol Biol Phys 1995;32:317-23. 11 Valicenti RK, Gomella LG, Ismail M et al. ... J Urol 2000;163:845-50. 16 Liauw SL, Webster WS, Pistenmaa DA, Roehrborn CG. ...
International Journal of Radiation Oncology*Biology*Physics, 2007
analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification a... more analyzed by Principle Component Analysis (PCA). Scores for factors were used for classification and results were correlated with clinically assessed radiation response. Results: PCA of spectra of 2 nd -fraction-of-radiotherapy tissues gave three clusters corresponding to complete response (CR), partial response (PR) and no response (NR), ). In this analysis we could discriminate no response and partial response conditions but there exists an overlap between complete and partial response conditions. We are also pursued predictive studies using tissues collected after 5 th fraction of EBRT in order to explore better discrimination between PR and CR conditions. The available results so for show good correlation with clinical response . Conclusions: The findings of the study thus suggest the feasibility of Raman spectroscopic prediction of tumor response to radiotherapy.